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Mayo Clinic Talks

Mayo Clinic Talks

Stay on top of your practice with podcasts from colleagues at Mayo Clinic.

All Episodes

Testosterone Supplementation in Men: Risks, Benefits & Best Practices

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Nahid Punjani, M.D., M.P.H Testosterone has a variety of health benefits. It helps maintain bone density, muscle mass, red blood cell production and sexual function. Testosterone levels in men tend to peak between age 30 to 40 then gradually decline and it’s not unusual to find low testosterone levels in men over the age of 50. It’s also known that in men with hypogonadism, testosterone supplementation can improve libido, bone density and muscle mass. Should we be checking testosterone levels in our middle-age male patients? How do we determine who should receive testosterone supplementation and finally what are the risks of supplementation? In this podcast, these are all questions I’ll be asking our guest, Nahid Punjani, M.D., M.P.H, a urologist at the Mayo Clinic as we discuss “Testosterone Supplementation in Men”. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 6, 2023
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Celiac Disease & Gluten Sensitivity: “No Loafing Matter”

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Amy S. Oxentenko, M.D. It’s estimated that less than 1/3 of individuals with celiac disease have been properly diagnosed. When those with celiac disease ingest gluten, an immune response develops which attacks the small intestine leading to inadequate absorption of nutrients. If left untreated, celiac disease can lead to a variety of nutritional deficiencies as well as other serious consequences. Those with celiac disease are also at increased risk for coronary disease and small bowel cancers. In this podcast we’ll review celiac disease and gluten sensitivity with our guest, Amy S. Oxentenko, M.D., a gastroenterologist at the Mayo Clinic. We’ll discuss the symptoms of celiac disease, how to diagnose the condition and how patients with celiac disease should be managed. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 30, 2023
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Sleep Medicine Edition | Violent Dreams, Sleepwalking & Other Strange Nighttime Events

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guests: Robin M. Lloyd, M.D., & Michael Silber, M.B. Ch.B. In most people, sleep is a peaceful activity. Dreaming is a normal component of our sleep and represents activity of the brain at a time the rest of our body is inactive. However, for some individuals sleep is not a peaceful activity. Some can experience very violent dreams, often associated with physical movements. Sleepwalking is another nighttime activity which some experience.  Violent dreams and sleepwalking can place the patient as well as others at risk for injury. How common are these behaviors? What causes them and how can these patients be treated. In this podcast, we’ll discuss violent dreams, sleep walking and other strange nighttime events with Mayo Clinic sleep specialists, Robin M. Lloyd, M.D., from the Department of Pediatrics and Adolescent Medicine and Michael Silber, M.B. Ch.B., from the Department of Neurology. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 25, 2023
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Food Allergy: Common Causes, Diagnosis & Treatment

Host: Darryl S. Chutka, M.D. @ChutkaMD Guest: Gerald W. Volcheck, M.D. Food allergy is an immune reaction that develops following ingestion of sometimes even a very small amount of the offending food product. It’s thought to occur in up to 4% of adults and is not to be confused with a food intolerance, which is much more common. It’s important to recognize patients who develop a food allergy as they can develop not only relatively benign problems such as GI symptoms or hives, but also more severe and potentially life-threatening conditions such as bronchospasm or even anaphylaxis. What are the most common foods that produce allergies? How should these patients be evaluated and how do we manage them? Our topic for this podcast is “Food Allergy” and these are some of the questions I’ll be asking our guest, Gerald W. Volcheck, M.D., from the Division of Allergic Diseases at the Mayo Clinic. https://www.usdairy.com/about-us/national-dairy-council Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 23, 2023
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Sleep Medicine Edition | Restless Leg Syndrome (RLS)

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Michael Silber, M.B. Ch.B. It’s estimated that up to 10% of the U.S. population has restless leg syndrome, with most patients middle aged or older. Since it tends to occur in the latter part of the day, it commonly interferes with an individual’s ability to sleep and is one of several known sleep disorders. Unfortunately, there is no cure, however there are a variety of treatment options available. The topic for this podcast is restless leg syndrome and my guest is sleep specialist and neurologist, Michael Silber, M.B. Ch.B., from the Mayo Clinic. We’ll discuss the symptoms and pathophysiology of restless leg syndrome, other medical conditions often confused with it as well as the various treatment options. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 18, 2023
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Women in Medicine

Hosts: Dawn Marie R. Davis, M.D. and Sanjeev (Sanj) Kakar, M.D. Guest: Erin K. O'Brien, M.D. Guest: Bobbi S. Pritt, M.D. Guest: Sandhya Pruthi, M.D. Our society is changing with women assuming more prominent roles. We have a female Vice President and recent books by Sheryl Sandberg (Lean In) and Michelle Obama (The Light We Carry), have highlighted the importance in inequities women have, and continue to have, on a daily basis. Mayo Clinic continues to evolve and lead this change in healthcare with female leaders incorporated throughout the practice. To celebrate this, we invited three dynamic physicians at Mayo Clinic’s Rochester campus, Erin K. O’Brien, M.D., Bobbi S. Pritt, M.D., and Sandhya Pruthi, M.D., to share their stories and perspectives in this week’s podcast. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 16, 2023
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Sleep Medicine Edition | Medications for Insomnia: What Works?

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Bhanuprakash (Bhanu) Kolla, M.D. A common question we get from patients is “What can you give me to help me sleep?”. Explaining how our sleep changes with age; becoming less efficient, more fragmented with multiple reasons for nighttime awakenings is met with understanding from the patient but is always followed by the question “So, what are you going to give me to help me sleep?”.  How does sleep change with aging? Why do we often have difficulty falling and staying asleep, and does the ideal pharmacologic agent exist that can be taken nightly, helps us fall asleep, remain asleep throughout the night and allow us to wake up feeling refreshed in the morning? In this podcast, we’ll discuss these questions with our guest, Bhanuprakash (Bhanu) Kolla, M.D., a psychiatrist from the Department of Psychiatry and Psychology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 11, 2023
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The Tick Talk of Lyme Disease: How to Diagnose & When to Treat

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Elitza S. Theel, Ph.D. Lyme disease is quite common with more than 400,000 new cases per year in the United States alone. It’s associated with a constellation of typical symptoms, but it can also produce symptoms which are very unusual and vague. As a result, it can mimic a variety of other diseases. An accurate diagnosis of Lyme disease can be challenging, often resulting in a delay or even lack of treatment. In this podcast, we’ll discuss the typical presentation of Lyme disease as well as some of its more unusual presenting symptoms. We’ll also cover how to establish a diagnosis and its current treatment recommendations. Our guest is Elitza S. Theel, Ph.D., a clinical microbiologist from the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 9, 2023
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Sleep Medicine Edition | Cognitive Behavioral Therapy for Treatment of Insomnia

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Michael H. Silber, M.B.Ch.B. Difficulty initiating and maintaining sleep is a common problem for many patients. Over-the-counter sleeping aids are used by many and we commonly get asked for prescription medications to help with their sleep. Unfortunately, the ideal sleeping medication doesn’t exist and many have potentially worrisome adverse effects, some produce daytime somnolence and others may have the potential to produce dependence. Cognitive behavioral therapy is an alternative treatment option to pharmacologic therapy and is safe, can be easily taught, and offers an alternative to the many with chronic insomnia. In this podcast, we’ll discuss this innovative treatment option with sleep expert, Michael H. Silber, M.B.Ch.B., a neurologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 4, 2023
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Seasonal Allergies: It’s Not Easy To Be Sneezy

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Mansi J. Kanuga, M.D. Millions of Americans suffer from seasonal allergies causing a variety of symptoms which often force them to stay indoors and limit their activities. Allergic rhinitis carries a significant economic burden accounting for an estimated 2 million lost school days, and 6 million lost workdays per year. Fortunately, there are numerous treatment options available. The topic for today’s podcast is seasonal allergies and our guest is Mansi J. Kanuga, M.D., an allergist at the Mayo Clinic. We’ll discuss how to use the patient’s history to determine the patient’s allergies, when allergy tests are indicated and management of seasonal allergies. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 2, 2023
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Sleep Medicine Edition | Sleep Apnea & its Complications

Host: Darryl S. Chutka, M.D., [@chutkaMD] Guest: Timothy I. Morgenthaler, M.D. It’s estimated that about 30 million people in the U.S. have sleep apnea and most don’t even know they have it. Only 20% of those with sleep apnea have been diagnosed with the condition. Sleep apnea becomes more common with advancing age and is thought to be present in up to 80% of men over the age of 80. With an increased prevalence of obesity in our population, the numbers of those with sleep apnea has increased dramatically. We’re all aware of the daytime drowsiness that is so common in patients who are untreated, but there are other numerous and potentially serious complications that can also occur. In today’s podcast, we’ll discuss the common presenting symptoms of sleep apnea, how to diagnose the condition, and the potential consequences in those who remain untreated. Our guest is Timothy I. Morgenthaler, M.D., a sleep specialist from the Division of Pulmonary and Critical Care Medicine at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 27, 2023
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Benign Scrotal Masses & Testicular Cancer Screening

Host: Darryl S. Chutka, M.D., [@chutkaMD] Guest: Bradley C. Liebovich, M.D. Testicular cancer accounts for only around 1% of all cancers in men and is most common in males from age 15 to 35. Around 10,000 new cases are diagnosed per year resulting in about 400 deaths. While testicular cancer is relatively uncommon, other abnormalities occur in the scrotum which are quite common and fortunately, relatively benign. Most of these conditions present as a scrotal mass and can be quite frightening to the patient if they discover them.  In today’s podcast, we’ll discuss scrotal masses including testicular cancer with our guest, Bradley C. Liebovich, M.D., from the Department of Urology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 25, 2023
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Sleep Medicine Edition | The Patient Who Cannot Tolerate CPAP: Alternative Approaches to Obstructive Sleep Apnea

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Eric J. Olson, M.D. It’s estimated that about 30 million people in the U.S. have sleep apnea and the worldwide prevalence is approaching 1 billion. The traditional treatment is continuous positive airway pressure or CPAP which is quite effective and used to enhance ventilation. Unfortunately, there are a significant number of patients with sleep apnea who can’t tolerate CPAP. This may result in an untreated patient, increasing their risks to a variety of potentially serious complications. How do we manage the CPAP-intolerant patient? What else is available for the patient with sleep apnea? Which patients are candidates for these alternative treatments and how effective are they? In this podcast, we’ll discuss these questions and more with our guest, sleep expert Eric J. Olson, M.D., from the Division of Pulmonary and Critical Care at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 20, 2023
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Sleep Medicine Edition | The Sleepy or Fatigued Patient: Yawning for Relief

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Michael H. Silber, M.B., Ch.B. Depending on the patient, a complaint of feeling tired, fatigued or sleepy may all mean the same thing. In others they may not feel that sleepiness is the same as fatigue or tiredness. Once we sort out what the patient is actually describing, how do we evaluate the sleepy patient? How much sleep do we need per night and what’s an inadequate amount of sleep? How do we evaluate the quality of a patient’s sleep and what role does age play in the evaluation of a patient’s sleep? These are questions we’ll discuss with our guest for this podcast, Michael H. Silber, M.B., Ch.B., a neurologist and sleep expert at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 18, 2023
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Liver Transplant Selection Criteria

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Michael D. Leise, M.D. The liver is the second-most transplanted organ; nearly 10,000 patients received a liver transplant in 2021. The major factor, which has limited the transplants performed, has been the availability of the donated organs and some patients have waited several years before an acceptable organ becomes available. Transplants can be performed for a variety of end-stage liver diseases, usually giving patients years of additional life. Who’s a candidate for a liver transplant and what criteria for selection are required? Our topic for this podcast is “Liver Transplant Selection Criteria” and we’ll discuss this topic with our guest, Michael D. Leise, M.D., from the Division of Gastroenterology and Hepatology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 11, 2023
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Post-Kidney Transplant Care for Primary Care Providers

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Samy M. Riad, M.D. Kidney transplants are quite common; over 20,000 transplants will have been performed by the end of 2022 and there are currently just under 90,000 individuals on the national transplant waiting list. They’ve been remarkably successful in giving patients with renal failure an improved quality of life. However, patients who have had kidney transplants have unique medical needs. Since most transplant patients will return to their primary care providers for the majority of their ongoing care, what important information do we need to successfully care for these patients? What unique medical needs do they have? And what potential health problems are more commonly seen in transplant patients? In this podcast, our guest, Samy M. Riad, M.D., a nephrologist at the Mayo Clinic will answer these questions and more as we discuss the management of the post-renal transplant patient. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 4, 2023
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Prostate Cancer & Men’s Health Edition | Primary Care Management of the Post-Prostate Cancer Patient

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Scott M. Cheney, M.D. Except for skin cancer, prostate cancer is the most common malignancy in males. 1 in 8 men will be diagnosed with prostate cancer during his lifetime, most over the age of 65. If diagnosed early, treatment is quite effective and results in a very favorable survival rate. Several very effective treatment options are now available for patients. In this podcast, we’ll discuss the various treatments and what patients can expect following each option. We’ll review how a post-prostate cancer patient should be followed by their primary care provider and when there might be reason for concern of a recurrence. The guest for this podcast is Scott M. Cheney, M.D., a urologist from the Mayo Clinic in Phoenix, Arizona. This episode is brought to you by: Astellas Oncology | https://astellasoncology.com/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 31, 2023
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Prostate Cancer & Men’s Health Edition | Updates in Advanced Prostate Cancer

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Alan H. Bryce, M.D. Prostate cancer is the second most common malignancy in men, second only to skin cancer and due to increased efforts in screening, most prostate cancers are found very early, and these men have an excellent survival rate. Unfortunately, a percentage of men develop an advanced prostate cancer and the disease becomes much more aggressive with significantly lower survival rates. Who’s at risk for advanced prostate cancer? How does the survival rate change with metastatic disease? Finally, what are the various treatment options and how effective are they? In this podcast, we’ll discuss these questions with our guest, Alan H. Bryce, M.D., from the Division of Hematology and Oncology at the Mayo Clinic. This episode is brought to you by: Astellas Oncology | https://astellasoncology.com/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 29, 2023
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Prostate Cancer & Men’s Health Edition | Prostate Cancer & Sexual Health

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Nahid Punjani, M.D., M.P.H. Issues related to the prostate can play a significant role in a man’s sexual function. We commonly use medications for benign prostate problems such as BPH which can produce adverse effects. It’s also very common for the treatment of prostate cancer, whether we use radiation therapy, surgical prostatectomy, or hormonal therapy to cause sexual dysfunction. In this podcast, we’ll review the important role the prostate plays in sexual function as we discuss the “Prostate and Sexual Health” with our guest, Nahid Punjani, M.D., M.P.H., a urologist at the Mayo Clinic. This episode is brought to you by: Astellas Oncology | https://astellasoncology.com/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 27, 2023
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Prostate Cancer & Men’s Health Edition | Treatment of Prostate Cancer

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: R. Jeffrey Karnes, M.D. Prostate cancer is the most common solid organ malignancy in males, and it’s estimated that 1 in 8 men will develop prostate cancer during their lifetime.  When diagnosed early, it has an excellent survival rate with a variety of very effective treatment options. What are the advantages and disadvantages of each?  Why would one option be chosen over another and how do the adverse effects of the various treatments differ? In this podcast, I’ll be discussing these questions with our guest, R. Jeffrey Karnes, M.D., a urologist at the Mayo Clinic. This episode is brought to you by: Astellas Oncology | https://astellasoncology.com/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 24, 2023
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Prostate Cancer & Men’s Health Edition | Screening for Prostate Cancer

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Daniel M. Frendl, M.D., Ph.D. Prostate cancer is one of the most common malignancies in men, second only to skin cancer. It’s estimated that 1 in 8 men will develop prostate cancer during their lifetime. The predominant screening test for prostate cancer has been the prostate specific antigen or PSA.  However, there has been some controversy surrounding the use of PSA. It’s an easily administered test, it’s relatively inexpensive and it’s capable of identifying men with possible prostate cancer. So, what’s the controversy? Is the PSA an effective screening test? Who should be tested and how have urologists modified their practice to manage patients with an elevated PSA? We’ll discuss these questions in today’s podcast on “Screening for Prostate Cancer” with our guest, Daniel M. Frendl, M.D., Ph.D., a urologist at the Mayo Clinic. This episode is brought to you by: Astellas Oncology | https://astellasoncology.com/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.   
March 22, 2023
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Prostate Cancer & Men’s Health Edition | Benign Prostatic Hyperplasia (BPH)

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Mitchell R. Humphreys, M.D. Benign prostatic hyperplasia or BPH is quite common in middle-age and older men. It’s estimated that up to 70% of men over age 60 have symptoms from BPH. While BPH is not a life-threatening condition, it does produce symptoms which can negatively affect the lifestyle of our patients. Since most of the patients with BPH are managed by primary care providers, we should be comfortable with the variety of treatment options available. When should treatment be initiated? What’s available pharmacologically? And when should a urologist be consulted to consider a surgical option? In this podcast, we’ll discuss these questions and more with Mitchell R. Humphreys, M.D., from the Department of Urology at the Mayo Clinic.  This episode is brought to you by: Astellas Oncology | https://astellasoncology.com/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.   
March 20, 2023
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Healthcare Professional Burnout: Contributors, Consequences & Solutions

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Colin P. West, M.D., Ph.D. The practice of medicine is often stressful and at times, even frustrating. Sometimes the stress and frustration can get out of hand and lead us to feeling overwhelmed and hopeless. This has been described as burnout. There’s good evidence to suggest that well over half of all physicians practicing in the U.S. have exhibited some symptoms of burnout at some time during their career. Healthcare professional burnout not only has negative consequences for the clinician, but also for patients, as patient care can often suffer. What are the symptoms of burnout, can we prevent them and how can we manage those who are experiencing professional burnout? We’ll discuss these questions and more with Colin P. West, M.D., Ph.D., an internist in the Division of General Internal Medicine at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 14, 2023
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Nutrition History Taking: A Practical Approach

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Tara Schmidt, MEd, RDN, LD Nutrition is so important to our health. What and how much we eat can help keep us healthy or increase our risk of developing a number of health problems including cardiovascular disease, diabetes, malignancy or a variety of degenerative health conditions. Unfortunately, many of our patients obtain their information regarding nutrition from the media which is often very inaccurate. It’s our responsibility as primary care providers to assess our patients’ nutritional status and give them accurate recommendations regarding dietary changes they should make in order to remain healthy. This starts with a nutritional history. Yet very few of us have had any formal education in nutrition. How do we take a nutritional history? What are the important questions to ask? We’ll discuss this and other nutritional issues with our guest for this podcast, Tara Schmidt, MEd, RDN, LD, a registered dietician at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 7, 2023
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THE BEST OF SEASON 1: Varicose Veins & Venous Insufficiency

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Thom W. Rooke, M.D. Today, we’re excited to bring back a special lecture by popular demand from Season 1 of Mayo Clinic Talks Podcast. We’ll be discussing varicose veins and venous insufficiency with Thom W. Rooke, M.D., from Cardiovascular Medicine at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
February 28, 2023
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Multiple Sclerosis: A Primary Care Perspective

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Eoin Flanagan, M.B., B.Ch. Nearly 1 million individuals in the U.S. have multiple sclerosis. Most acquire the disease between the ages of 20 and 50. It’s often difficult to establish a diagnosis as the symptoms can be vague and often vary significantly from one individual to another.  The disease can be very frightening, often debilitating, and progressive; up until recently, we’ve had very little to offer patients in the way of treatment.  However, in the past few years there have been numerous advances in treatment options which have given hope to the many patients with MS. We’ll be discussing multiple sclerosis in this podcast. Our guest is Eoin Flanagan, M.B., B.Ch., a neurologist from the Department of Neurology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
February 21, 2023
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Determining the Source of GI Blood Loss

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Andrew C. Storm, M.D. Determining the source of GI blood loss can be a challenging dilemma. On occasion, we have clues regarding where we should start looking, but in some cases, no such clues exist. It’s best to use a stepwise approach to determining the source and in most cases, this will give us the answer we need. When a cause is found, most tend to be from an upper GI source rather than the colon. Whereas an upper endoscopy and colonoscopy will determine the source in the majority, in some cases, more aggressive techniques are required. In this podcast, we’ll be discussing GI blood loss, and which approach we should use to determine the source. Our guest is Andrew C. Storm, M.D., a gastroenterologist from the Division of Gastroenterology and Hepatology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
February 14, 2023
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Year 3 of COVID-19: Harsh Truths, Brutal Realities & Glimmers of Hope

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Greg A. Poland, M.D. [@drgregpoland] Severe acute respiratory syndrome coronavirus 2, also known as COVID-19, is a novel virus with a rapidly changing genotype. It’s responsible for over a million deaths so far. One of every 300 Americans have died as a result of the virus and infection with COVID-19, and it has been responsible for a reduction in life expectancy in the U.S. for both 2021 and 2022. There are 4 widely available, approved vaccines in the United States, yet an inadequate number of individuals have been immunized and very few are still wearing protective masks. The consequences of this include continued excess morbidity and mortality as well as the development of a variety of new variants of the virus. Our guest for this podcast is Greg A. Poland, M.D., an internist, and the director of vaccine research at the Mayo Clinic. He’s also the lead author of an article published in Mayo Clinic Proceedings in December 2022. The article is entitled “Year 3 of COVID-19: Harsh Truths, Brutal Realities and Glimmers of Hope”. We’ll be discussing some of the key points from this article. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
February 7, 2023
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THE BEST OF SEASON 1: Effective Communication Skills for a Time Strapped Practice

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Daniel L. Hurley, M.D. Today we’re excited to bring back a special lecture by popular demand from Season 1 of Mayo Clinic Talks Podcast. Today we’re joined by Daniel L. Hurley, M.D., a Mayo Clinic Endocrinologist and heavily awarded educator and practitioner. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 31, 2023
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How to Use Pulmonary Function Tests Effectively

Host: Darryl S. Chutka, M.D.  [@chutkaMD;] Guest: Alexander S. Niven, M.D. Pulmonary function tests are extremely useful in both diagnosing and managing patients with respiratory disease. In addition to a medical history, physical exam and imaging studies, they give us a great deal of information of the pulmonary physiology and help us understand why patients have various respiratory symptoms. However, there are quite a number of pulmonary function tests available to us and which tests we should order can be confusing. Do we know when spirometry, lung volumes or diffusion capacity will be useful for evaluating the various pulmonary conditions? Our guest for this podcast is Alexander S. Niven, M.D., from the Division of Pulmonary and Critical Care Medicine at the Mayo Clinic and he’ll provide answers to these questions and more as we discuss “How to Use Pulmonary Function Tests Effectively”. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 24, 2023
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Obesity Update in Women

Guest: Ekta Kapoor, M.B.B.S. Host: Darryl S. Chutka, M.D. [@chutkaMD] Obesity is becoming a serious epidemic in the United States, and it’s estimated that if current trends continue, by 2030 nearly half of all adults in the U.S. will be obese. Prevalence rates of obesity are steadily increasing in both men and women and some of the highest rates are seen in post-menopausal women. Obesity carries an increased risk for a variety of medical conditions and death rates of several types of cancer increase in obese women. The topic for this podcast is obesity in women and our guest is women’s health expert, Ekta Kapoor, M.B.B.S., from the Mayo Clinic. We’ll discuss reasons women tend to develop obesity in middle age, the risks associated with the type of obesity that occurs following menopause and effective strategies to manage weight gain with aging in women. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 17, 2023
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THE BEST OF SEASON 1: The Risks & Benefits of Coffee

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Donald D. Hensrud, M.D., M.S. Today we’re excited to bring back a special lecture by popular demand from Season 1 of the Mayo Clinic Talks Podcast. Darryl S. Chutka, M.D., a general internist at Mayo Clinic in Rochester, Minnesota, and Donald D. Hensrud, M.D., M.S., a physician in Preventative Medicine & the Medical Director for the Mayo Clinic Healthy Living Program discusses the risks and benefits of drinking coffee. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 10, 2023
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Sudden Cardiac Arrest in Athletes

Host: Sanjeev (Sanj) Kakar, M.D., [@sanjkakar] Guest: Michael J. Ackerman, M.D., Ph.D. Guest: Thomas M. Munger, M.D. Much attention has been paid to sudden cardiac arrest in athletes. Did you know the likelihood of sudden cardiac arrest in high school athletes is between 1 in 50,000 to 1 in 80,000 and for college-aged players, the risk is estimated at 1 in 13,426. Among National Collegiate Athletic Association (NCAA) athletes, there is an increased risk in those who are male, of black race and play basketball. In this podcast, we discuss what the causes of sudden cardiac arrest are, the role of screening protocols and what can be done in patients who experience this event with cardiology experts Tom M. Munger, M.D., and Michael J. Ackerman, M.D., Ph.D. SPECIAL EPISODE: https://ce.mayo.edu/content/mayo-clinic-talks-podcasts-special-episode-sudden-cardiac-arrest-athletes Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 9, 2023
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Management of Patients with Late-Stage Dementia: A Caring Hand

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Mairead M. Bartley, M.B., B.Ch., B.A.O. Dementia is a devastating health condition for patients, their families, and a challenging disease for primary care providers. Whereas the diagnosis is usually straightforward to establish, the pharmacologic treatment options have been, at best, disappointing. With little to nothing to offer our patients which would improve their cognitive status; our responsibility for their management doesn’t end there. We still have a responsibility to provide ongoing care to these patients as well as their caregivers as they progress into the later stages of dementia. This brings up numerous management challenges including maintaining our patient’s independence, as well as numerous safety and nutrition issues. This podcast will review the management of the patient with later stage dementia with our guest is Mairead M. Bartley, M.B., B.Ch., B.A.O., a geriatrician and internist in the Division of Community Medicine at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 3, 2023
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Alternative Therapies for Hyperlipidemia: The Lipid-ome of Lowering Cholesterol

Host: Darryl S. Chutka, M.D. [@ChutkaMD] Guest: Stephen Kopecky, M.D. [@DrSteveKopecky] Hyperlipidemia is extremely common in the U.S., and we have a variety of pharmacologic agents which are very effective in treating this condition and improving our patients’ lipid profile. Yet there are patients who have elevated lipids but may not meet the criteria for pharmacologic therapy and other patients who don’t tolerate the medications we commonly prescribe. What are the alternative treatments available for managing hyperlipidemia and how effective are they?  How do they compare with pharmacologic therapy? We’ll discuss these issues and more in this podcast with our guest, preventive cardiologist Stephen Kopecky, M.D., from the Mayo Clinic.  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
December 27, 2022
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Hand & Wrist Disorders: Lend Me a Hand (& Wrist)

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Sanjeev (Sanj) Kakar, M.D. [@sanjkakar] The hand and wrist are very complex parts of our anatomy and composed of multiple tendons, muscles, and nerves. The hand also contains over 30 bones. Hand or wrist complaints are some of the more common reasons patients come to their primary care provider, and at times, the cause can be quite elusive. We need to be able to accurately assess the patient’s symptoms, diagnose the various disorders and determine which ones need to be referred for specialty care and which ones we can manage on our own. In this podcast, we’ll discuss some of the most common hand and wrist disorders with Sanjeev Kakar, M.D., a hand specialist from the Department of Orthopedics at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
December 20, 2022
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Chronic Kidney Disease: What Primary Care Providers Need to Know

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Mira T. Keddis, M.D. [@keddis_mira] Chronic kidney disease can have a major impact on a patient’s quality of life; reducing their energy level, impacting their diet and may limit medications or alter medication dosages we prescribe. It’s estimated that kidney disease affects nearly 40 million people in the U.S. or 15% of the population, and two out of five adults with severe kidney disease don’t even know they have it. As primary care providers, we need to know how to prevent kidney disease, how we assess renal function and how to manage those with moderate to severe renal impairment. Our guest for today’s podcast is Mira T. Keddis, M.D., a nephrologist at the Mayo Clinic in Scottsdale, Arizona. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
December 13, 2022
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Glaucoma: Not So Easy on the Eyes

Guest: Cheryl L. Khanna, M.D. Host: Darryl S. Chutka, M.D.  [@chutkaMD] Glaucoma is a very common eye disease affecting more than 70 million people worldwide and it’s a leading cause of blindness, accounting for over 12% of blindness around the world. While it tends to be more common in older individuals, it can occur in younger patients as well. There are a variety of types of glaucoma as well as several new treatment options available. In this podcast, we’ll discuss the various types of glaucoma, its treatment options and what we should do as primary care providers to help patients get a proper diagnosis and prevent the vision loss which can be associated with glaucoma. Our guest is Cheryl L. Khanna, M.D., an ophthalmologic surgeon at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
December 6, 2022
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Abortion: What the Primary Care Provider Should Know

Guest: Regan N. Theiler, M.D., Ph.D. Host: Darryl S. Chutka, M.D. @chutkaMD Abortion is a common procedure. three out of ten pregnancies and six out of ten unintended pregnancies end with an induced abortion. Overall, about one in four women in the U.S. will have an abortion by the age of 45 years. The U.S. Supreme Court’s June 2022 ruling to overturn Roe vs. Wade has shifted the legal battle over abortion to the states, resulting in some states prohibiting abortion and others moving to safeguard it. The topic for this podcast is abortion and what the primary care provider should know. Our guest is Regan N. Theiler, M.D., Ph.D., from the Department of Obstetrics and Gynecology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. Faculty Twitter:  [@chutkaMD; https://twitter.com/ChutkaMD] 
November 29, 2022
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Vaccine Recommendations: 2022 Important Updates

Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Robert M. Jacobson, M.D. [@RobertJMD] Immunizations are one of the greatest success stories in modern medicine and it’s estimated that they’ve saved more lives and prevented more disabilities than any other medical intervention. They’re probably responsible, more than any other medical advance, in contributing to our increased longevity as a population. They’re also extremely cost-effective and their benefits far outweigh the very small risks they carry. This podcast will review new information regarding immunizations and how we as clinicians can increase our patients’ immunization rates. Our guest is Robert M. Jacobson, M.D., a pediatrician, and expert in immunizations from the Department of Pediatrics at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  Faculty Twitter:  [@chutkaMD; https://twitter.com/ChutkaMD]  [@RobertJMD; https://twitter.com/robertjmd]
November 22, 2022
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What To Know About Home Genetic Testing

Guest: Matthew J. Ferber, Ph.D. Host: Darryl S. Chutka, M.D. [@chutkaMD] Over the past decade or so, we’ve learned a great deal about the human genome, and this has allowed us to determine which medical conditions our patients are at an increased risk of developing and which medications may be best suited for their medical problems. In addition to the clinical genetic tests we use in our practice, direct to consumer home genetic testing has become extremely popular. This podcast will review home genetic testing and what information patients can expect with these tests, whether the information they receive is accurate and how home genetic testing differs from the genetic tests we order. Our guest is Matthew J. Ferber, Ph.D., a clinical molecular geneticist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
November 15, 2022
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Evaluation & Management of Osteoporosis: Make No Bones About It

Host: Darryl S. Chutka, M.D. (@chutkaMD) https://twitter.com/ChutkaMD Guest: Kurt A. Kennel, M.D. Hip fractures have had a major impact on our healthcare system with an economic burden estimated to be over $20 billion per year. Due to the increasing age of our population, they’ll have an even greater impact in the future. In addition to the economic burden, hip fractures often result in major changes to one’s lifestyle. As a result, the detection, prevention and management of osteoporosis becomes an important health strategy. The topic for this podcast is osteoporosis and our guest is Kurt A. Kennel, MD., a Mayo Clinic Endocrinologist, and specialist in bone metabolism. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
November 8, 2022
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Reducing Medical Supply Chain Vulnerability: Now You See It, Now You Don’t

Guest: Pritish K. Tosh, M.D. (@DrPritishTosh) Host: Darryl S. Chutka, M.D. (@chutkaMD) The COVID-19 pandemic exposed the vulnerability of the medical product supply chain and its impact on providing optimal healthcare. The spread of the disease was accompanied by not only shortages of personal protective equipment but also medications and many other products we depend on every day in our clinical practice. We’ve learned that we cannot provide adequate or timely health care when there are shortages of important products. As a result, the health of our patients and healthcare providers has been endangered. It’s also resulted in a rationing of care and an increased risk of error as we’re forced to use sub-standard or replacement products. It’s caused us to look for new solutions to reduce our medical supply chain vulnerabilities. Our guest for this podcast is Pritish K. Tosh, M.D., an infectious disease specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  Twitter Handles: (@chutkaMD); https://twitter.com/ChutkaMD  (@DrPritishTosh); https://twitter.com/drpritishtosh
November 1, 2022
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Colon Polyps: A Real Bum-mer

Guest: John B. Kisiel, M.D. (@DrJohnKisiel) Host: Darryl S. Chutka, M.D. (@chutkaMD) Colon polyps are relatively common in our population and, in most cases, are relatively easily found and removed, thereby reducing one's risk of developing colorectal cancer. What are the various types of colon polyps and which polyps have a greater tendency to become malignant? How long does it take a polyp to develop into colon cancer and how often does colonoscopy miss polyps?  These are just some of the topics we’ll discuss in today’s podcast. Our guest is John B. Kisiel, M.D., a gastroenterologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 25, 2022
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Genes & Your Health Edition: Precision Medicine for Obesity: From Phenotypes to Multi Omics

Host: Denise M. Dupras, M.D., Ph.D. Guest: Andres J. Acosta, M.D., Ph.D. (@dr_aac) The obesity epidemic continues to escalate in the United States and obesity rates are increasing around the world. It is estimated that by 2030, 50% of adults and 25% of children worldwide will be obese. Patients are the interaction of their genetics and environment; this episode explores the importance of understanding the mechanisms behind food intake regulation and weight to develop individualized therapies to treat obesity. Our guest for this episode is Andres J. Acosta, M.D., Ph.D., a physician-scientist at Mayo Clinic in Rochester, Minnesota. He is also an assistant professor of medicine at Mayo Clinic College of Medicine and Science, and principal investigator of the Precision Medicine for Obesity Laboratory.
October 20, 2022
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Uterine Fibroids: Under Pressure

Guest: Elizabeth (Ebbie) A. Stewart, M.D. Host: Darryl S. Chutka, M.D. Uterine fibroids are the most common tumor of the female reproductive tract and women who are approaching menopause are at greatest risk for having them. In most cases, they don’t produce symptoms and only a minority of women require treatment. The topic for this podcast is uterine fibroids and we’ll discuss how fibroids can be diagnosed, their most common symptoms, who requires treatment and some of the latest treatment options with our guest, Elizabeth A. Stewart, M.D., from the Department of Obstetrics and Gynecology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 18, 2022
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Genes & Your Health Edition: Epigenomics Research – Understanding Genetics of Treatment Resistance

Guest:   Alexandre Gaspar Maia, Ph.D. (@gasparma1a) Host: Denise M. Dupras, M.D., Ph.D. Epigenomics is a fascinating field in which researchers chart the locations and understand the functions of all chemical tags that mark the genome. The epigenome is the first boundary from the exterior world to our DNA sequence, and it can change dramatically. This episode discusses the state of the art of epigenomics analysis and the epigenome in the context of specific cells. Additionally, it explores the future of epigenomics for individualized medicine and in better understanding genetics of treatment resistance. The guest for this episode is Alexandre Gaspar Maia, Ph.D., an assistant professor in the Functional Genomics Laboratory at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 13, 2022
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Scoliosis: Around The Bend

Host: Edward R. Laskowski, M.D Guest: Anthony A. Stans, M.D. The evaluation and treatment of scoliosis is an area that has created some controversy over the years.  Should we be screening kids in school?  When do we brace kids with scoliosis?  And what are the indications for surgery? To help us answer these questions and more, I am delighted to welcome Anthony A. Stans, M.D., a consultant in the Division of Pediatric Orthopedic Surgery with special interest in the treatment of spinal deformity.  He is past Chair of the Mayo Clinic Division of Pediatric Orthopedic Surgery and past Surgeon in Chief for the Mayo Clinic Children’s Center. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 11, 2022
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Genes & Your Health Edition: Neurodegenerative Brain Disease

Guest: Bradley F. Boeve, M.D. Host: Denise M. Dupras, M.D., Ph.D. Family history is so important in deciphering genetic causes for neurodegenerative disorders. As we study polygenetic situations, we are learning that often it is not just one gene, but the contribution of multiple genes that lead to the presentation of a patient with cognitive or brain function deterioration that occurs at a variable rate. In this episode, we discuss genes and neurodegenerative brain disease, and our guest is Bradley F. Boeve, M.D., a consultant in the Department of Neurology and the Center for Sleep Medicine, as well as a professor of neurology at the Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 6, 2022
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Psoriasis: Let’s Talk Rash-tionally

Host: Darryl S. Chutka, M.D. @chutkaMD Guest: Jason C. Sluzevich, M.D. Psoriasis is a somewhat atypical dermatologic condition which can come and go over time. In many, there may be seasonal effects and in some, psoriasis can have an associated arthritis. It has a characteristic distribution and while it has no cure, there are a variety of established and new treatment options. In this podcast, we’ll review how to diagnose psoriasis, its characteristic appearance, its associated arthritis, and management strategies with Jason C. Sluzevich, M.D., a dermatologist from the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 4, 2022
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Genes & Your Health Edition: Breast Cancer & SNPs- What Are They & What Do We Know?

Guests: Sandhya Pruthi, M.D. (@DrSandhyaPruthi) Host: Denise M. Dupras, M.D., Ph.D. What is precision prevention? As providers, what can we do to best determine who is at high risk for breast cancer, and when to make appropriate decisions about interventions to reduce an individual’s risk for getting breast cancer? In this episode of our Genes & Your Health edition from the Center for Individualized Medicine, we will learn more about breast cancer, breast cancer genes and the role of single nucleotide polymorphisms (SNPs) in breast cancer risk assessment. Our guest is Sandhya Pruthi, M.D., a Mayo Clinic physician in breast disease and a consultant and Professor of Medicine in the Department of General Internal Medicine in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 29, 2022
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Helping Your Patients Live Younger Longer

Host: Darryl S. Chutka, M.D.  @ChutkaMD Guest: Stephen Kopecky, M.D. Most of us want to live longer, but we want to live a healthy life and avoid the many health problems associated with growing older. Many of the health issues associated with aging have significant morbidity and have the potential to significantly affect our quality of life. Do we know how to avoid these health problems and stay healthy into our older ages? What should we be advising our patients to help them live younger longer? We’ll discuss these questions with our guest today, Stephen Kopecky, M.D., a preventive cardiologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 27, 2022
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Genes & Your Health Edition: Polycystic Kidney Disease & Genetic Testing – Aiming for Accurate Diagnosis

Guest: Fouad T. Chebib, M.D. Host: Denise M. Dupras, M.D., Ph.D. What is polycystic kidney disease? Is it all genetic? As providers, what should we be considering and what patients should we think about screening with genetic testing? Join this episode of our Genes & Your Health edition from the Center for Individualized Medicine to learn more about the role of genes in polycystic kidney disease. This episode features Fouad T. Chebib, M.D., a Mayo Clinic nephrologist from Jacksonville, Florida, whose specialty is in polycystic kidney disease. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 22, 2022
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Genes & Your Health Edition: Exposomics – The Next Frontier

Guest: Konstantinos N. Lazaridis, M.D. Host: Denise M. Dupras, M.D., Ph.D. What does the exposome mean? In this episode, we will define the exposome and explore how assessing exposures in an organized fashion will help us better understand the gene environment interaction. The guest for this episode of our Genes & Your Health edition from the Center for Individualized Medicine is Konstantinos N. Lazaridis, M.D., a Mayo Clinic physician in the Division of Gastroenterology and Hematology, as well as the Bernard and Edith Waterman Director, Microbiome Program, Center for Individualized Medicine and Carlson and Nelson Endowed Director, Center for Individualized Medicine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 20, 2022
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Monoclonal Gammopathy of Undetermined Significance (MGUS)

Host: Darryl S. Chutka, M.D. (@ChutkaMD) Guest: Wilson I. Gonsalves, M.D. Monoclonal gammopathies represent abnormal proteins produced by plasma cells. The most common monoclonal gammopathy is monoclonal gammopathy of undetermined significance or MGUS. While MGUS itself is not a malignancy and doesn’t require treatment, patients with MGUS have an increased risk of developing a variety of hematologic malignancies and therefore do require surveillance. The topic for today’s podcast is monoclonal gammopathy of undetermined significance and our guest is Wilson I. Gonsalves, M.D., a hematologist and oncologist from the Division of Hematology at the Mayo Clinic. We’ll discuss how to diagnose MGUS, who is more likely to develop this condition and how patients with it should be followed.  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 13, 2022
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Mayo Clinic Q&A: Updated COVID-19 boosters target omicron variants

This episode is shared from Mayo Clinic Q&A and was recorded on August 31, 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The first significant change to COVID-19 vaccines since their rollout came this week as the Food and Drug Administration granted emergency use authorization for updated Moderna and Pfizer COVID-19 boosters aimed at the omicron variants. The Centers for Disease Control and Prevention (CDC) also signed off on the recommendation, clearing the way for the new COVID-19 booster to be administered. The new boosters are bivalent vaccines, meaning they target more than one strain of the virus. The new formulation targets the BA.4 and BA.5 omicron variants, in addition to the original coronavirus strain. BA.5 is responsible for nearly 90% of all new COVID-19 cases in the U.S., according to the CDC. The Pfizer bivalent booster is approved for people 12 and up if they have already received their primary COVID-19 vaccine series and it has been at least two months since their last vaccine dose. The Moderna bivalent booster is available on the same timeline to people 18 and up. "This booster recommendation is in anticipation that there will be yet another surge as college students, grade school and high school students are gathering back together," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "We're also preparing for cooler weather, meaning more indoor activities, family gatherings and the holidays — often without masks, unfortunately. We still need to take COVID seriously." Another big concern for vaccine experts is the upcoming flu season. The Southern Hemisphere is often an indicator of what's to come for the U.S. Australia's flu season exceeded its five-year average, particularly affecting children under age 5, according to a recent report. Experts worry that the relaxing of masking and social distancing recommendations that were in place for COVID-19 purposes the past two winters will be a factor. These measures also protected people from the flu. "When cold weather moves us indoors, a high viral circulation occurs in schools and other indoor settings. I think we are very likely to see a bad flu year," says Dr. Poland. "Now I know we've been predicting that for two years, but for the most part, people wore masks and it didn't happen. I don't think that'll be the case this year. People are not wearing masks, and we are very likely to get hit hard by influenza." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news and touches on other news, including monkeypox, polio and the upcoming flu season.  
September 6, 2022
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Plantar Fasciitis: Best Step Forward

Host: Joshua D. Luciew, P.A.-C. Guest: Arthur J. De Luigi, D.O., M.H.A. (@DrDeLuigi, https://twitter.com/drdeluigi) Heel and foot pain can be a burdensome symptom for our patients, as discomfort can be experienced with each step they take, hindering locomotion. Many different patient populations are required to be on their feet for their job or for various wellness goals, which can exacerbate their painful heel and foot or deter them from exercise. In this episode, we will explore the most common cause of heel and foot pain: plantar fasciitis. Listeners will learn from a Mayo Clinic specialist in Physical Medicine and Rehabilitation how plantar fasciitis develops, how it is properly diagnosed, and learn the best approaches for treatments of this condition to help patients resume their previous physical activities, pain-free. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 6, 2022
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Peripheral Neuropathies: On Pins and Needles

Host: Darryl S. Chutka, M.D. (@ChutkaMD) Guest: Julie A. Khoury, M.D. Peripheral neuropathy is a relatively common neurologic condition we frequently see in primary care. Some patients may describe the symptoms as paresthesias and they represent a minor nuisance, however others may have very painful dysesthesias. Since some peripheral neuropathies are reversible, we need to know when to suspect a peripheral neuropathy, how to evaluate patients who have them and the possible treatment options. We’ll discuss peripheral neuropathies in this podcast with Julie A. Khoury, M.D., a neurologist at the Mayo Clinic in Phoenix, Arizona. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 30, 2022
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Kidney Stones: This Too Shall Pass

Host: Darryl S. Chutka, M.D. (@ChutkaMD) Guest: Ivan E. Porter, II M.D. Kidney stones are quite common and represent one of the most common disorders of the urinary system. When symptomatic, stones are relatively easy to diagnose as they tend to cause a very characteristic clinical presentation. While most stones will pass through the urinary system, others will require a variety of treatment options. The topic for today’s podcast is kidney stones and we’ll discuss the diagnosis, management, and prevention of stones with Ivan E. Porter, II M.D., a nephrologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 23, 2022
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Managing Hypertension in the Elderly

Guest: Sandra J. Taler, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) It’s estimated that over 70% of those 65 and older have hypertension and there’s good evidence to show that less than half of these elderly individuals are adequately controlled. While there are many similarities between hypertension in the elderly and the general population, there are also some important differences. The elderly are more likely to have systolic hypertension, take multiple medications and they’re more likely to experience more frequent and serious adverse drug reactions. In this podcast, we’ll learn more about hypertension in the elderly from Sandra J. Taler, M.D., a nephrologist and hypertension specialist at the Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 16, 2022
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Treating Sacroiliac (SI Joint) vs. Chronic Lower Back Pain

Host: Sanjeev (Sanj) Kakar, M.D. (sanjkakar) Guest: William W. Cross, III, M.D. (@WilliamCross3MD) Did you know the lifetime prevalence of generalized low back pain is estimated at 60% to 70% in industrialized countries? Often overlooked, the sacroiliac or SI joint can cause approximately one third of these cases. How do you determine the difference between the two? In this week’s podcast, we discuss the diagnosis of SI joint dysfunction and the different modalities for treatment, including non-operative and surgical management with William W. Cross, M.D., an Associate Professor in the Department of Orthopedic Surgery at Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  Resource:   Sacroiliac Joint Clinic in Minnesota - Overview - Mayo Clinic
August 9, 2022
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Headache Edition: Status Migrainosus and Headache in the ER

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Mark A. Whealy, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Headache disorders are extremely common, and patients frequently seek our help in the outpatient setting regarding management of their headaches. On occasion, they may present to the emergency department for more severe or prolonged headaches. With this podcast, we will continue our series on headaches as we discuss intractable migraine, also known as status migrainosus. We’ll also discuss other headaches commonly seen in the emergency department. How serious is status migrainosus? How should patients with these headaches be evaluated and what are the most effective management strategies? We’ll discuss these questions with Mark A. Whealy, M.D., a neurologist and headache specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 4, 2022
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Endometriosis: An Issue with Tissue

Guest: Tatnai L. Burnett, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Endometriosis affects approximately one in ten women during their reproductive age and can result in chronic abdominal symptoms, including pelvic pain and at times infertility. It can produce a variety of vague symptoms which commonly causes a delay in establishing a diagnosis. Since women commonly present to their primary care providers, we need to consider endometriosis as a cause of their symptoms. While there is no cure, this chronic condition can be effectively managed. The topic for this podcast is endometriosis and our guest is Tatnai L. Burnett, M.D., from the Department of Obstetrics and Gynecology at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 2, 2022
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Headache Edition: Pediatric Headaches

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Juliana H. VanderPluym, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Headaches in children are relatively common and although there are many similarities to headaches in adults, there are some differences as well. Symptoms can be slightly different, and these differences can make it more difficult to establish a specific diagnosis in a child. This podcast will continue our series on headaches and the topic will be “Headaches in Children”. We’ll cover such topics as: Do infants get headaches? How often are headaches in children serious? And is the management of headaches in children any different than in adults? Our guest for this topic is Juliana H. VanderPluym, M.D., a neurologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 28, 2022
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Elevated Triglycerides: Implications for Cardiovascular Health

Host: Joshua D. Luciew, MPAS, P.A.-C. Guest: Abigail K. Stockland, APRN, C.N.P., M.S.N. Guest: Michaeleen M. Burroughs, M.S., RDN, LD A fasting lipid panel is part of a patient’s routine health maintenance visit. This common laboratory test has many values on it including total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides. This test helps clinicians calculate a patient’s 10-year atherosclerotic cardiovascular disease risk (ASCVD risk) to help guide treatments. If a patient's risk is determined to be high, statin medications can be considered. However, despite using statin therapy and addressing modifiable risk factors, some patients still have elevated triglycerides.  What role do triglycerides play in a patient's health?  Does hypertriglyceridemia contribute to cardiovascular disease? Tune in to this episode to find out more from our panel discussion. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
July 26, 2022
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Headache Edition: Serious Secondary Headaches

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Chia-Chun Chiang, M.D. (@chiachunchiang) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Headaches have a variety of causes and for most they are a minor nuisance. Fortunately, most have a benign cause. However, there are some headaches which are associated with a serious health problem. Since many of these patients will present to their primary care providers with their headaches, we need to recognize clues they may describe that allow us to suspect their headache may not be benign. In this podcast, we’ll continue our series on headaches and discuss serious, secondary headaches with Chia-Chun Chiang, M.D., a neurologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 21, 2022
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The Outs and Ins of Vitamins

Guest: Donald D. Hensrud, M.D., M.S. Host: Edward (Edward R.) R. Laskowski, M.D. (@DrEdSportsMed) A recent Harris poll found that 86% of people take some sort of vitamin or supplement, and a recent research study found that approximately 60% of people report using dietary supplements in the past 30 days.  Multiple claims are made regarding the benefits of vitamins. How do we know which are true?  How do we sift through all the hype? When should we consider taking vitamins or recommending them for our patients? This episode features Donald D. Hensrud, M.D., M.S., an Associate Professor of Nutrition and Preventive Medicine at Mayo Clinic Rochester, Director of the Mayo Clinic Healthy Living Program, and editor of multiple books on healthy eating and living a healthy lifestyle, including The Mayo Clinic Diet and The New Mayo Clinic cookbook. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 19, 2022
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Mayo Clinic Q&A: BA.5 omicron variant fueling latest COVID-19 surge

This episode is shared from Mayo Clinic Q&A and was recorded in July 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Danielle (DeeDee) J. Stiepan The BA.5 omicron variant is now the dominant strain in the U.S., and it is leading to a new wave of COVID-19 infections. BA.5 was responsible for nearly 54% of COVID-19 cases in the U.S., and BA.4, a similar variant, accounted for another 17%, according to the latest data from the Centers for Disease Control and Prevention.  Experts are concerned because this particular variant appears to be good at evading the immune system.  "This BA.5 variant is hypercontagious, and right behind it, new variants are coming," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "We will continue to generate these variants until people are masked and immunized."  Dr. Poland explains that the transmissibility of BA.5 represents the evolution of the virus to become more contagious and able to evade immune protection from previous infection or vaccination.  "Whether you've been vaccinated, whether you've been previously infected, whether you've been previously infected and vaccinated, you have very little protection against BA.5 in terms of getting infected or having mild to moderate infection," says Dr. Poland. "Thankfully, you still do have good protection against dying, being hospitalized or ending up on a ventilator if you are up to date on your vaccinations."  Due to the consequences of reinfection, including the possibility of long COVID-19, Dr. Poland urges people to continue to take precautions to protect themselves. "The reality is, it's important to be up to date on the COVID-19 vaccinations that are recommended for your age group, health condition, etc.," says Dr. Poland. "Sometime this fall, we may well have a variant-focused vaccine, so get it when it becomes available. And wear a proper mask properly when you are indoors around people who are not your family or in a crowded outdoor venue." On the Mayo Clinic Q&A podcast, Dr. Poland shares the latest COVID-19 news and answers listener questions.
July 18, 2022
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Headache Edition: Unusual Headaches

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Narayan R. Kissoon, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Headaches are quite common and essentially everyone has experienced them; some have more than others. While most headaches are merely an annoyance, others can be quite debilitating and result in missed work and lost productivity. While tension headaches are the most common overall, migraines are the type most often seen by healthcare providers. While tension and migraines represent the majority of headaches, it’s important for healthcare providers to recognize when a headache falls into the unusual category. This podcast will continue our series on headaches with our guest, Narayan R. Kissoon, M.D., a neurologist and headache specialist at the Mayo Clinic as we discuss unusual headaches. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 14, 2022
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Selection Criteria for Kidney Transplantation

Guest: Carrie A. Schinstock, M.D. (@caschinstock) Host: Darryl S. Chutka (@ChutkaMD) Kidney transplants were initially performed in the early 1950’s; however, most of these early transplants failed due to immune system rejection. Successful transplants were generally limited to those performed in identical twins. With the discovery of immunosuppressant therapy, organ rejection became less of an issue and successful kidney transplants have become more common. Currently, in the U.S. over 20,000 kidney transplants are performed annually. Who is a candidate for a kidney transplant? What is the current success rate and what is the optimal timing for a transplant in patients with end stage renal disease? We’ll discuss these questions in this podcast on kidney transplantation with our guest, Carrie A. Schinstock, M.D., a nephrologist from the Division of Nephrology and Hypertension at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
July 12, 2022
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Headache Edition: Chronic Daily Headaches

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Rashmi B. Halker Singh, M.D. (@rashmihalker) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Essentially everyone has an occasional headache and it is usually nothing more than a minor nuisance. However, there are individuals who have very frequent headaches, and they can have a significant influence on that person’s lifestyle and quality of life. The topic for this podcast is chronic daily headache, which represents a description of a variety of both primary and secondary headaches that occur frequently. Our guest is Rashmi Halker Singh, M.D., a neurologist, and specialist in headache medicine at the Mayo Clinic in Scottsdale, Arizona. We’ll discuss what types of headaches patients with chronic daily headache tend to have, how this syndrome develops, and how you should evaluate and manage these patients. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 7, 2022
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Cervical Cancer Screening

Host: Darryl S. Chutka, M.D. (@ChutkaMD) Guest: Kathy L. MacLaughlin, M.D. Worldwide, cervical cancer is a very common malignancy for women, although the number of new cases in the U.S. has been declining. The overwhelming majority of cases are caused by infection with the human papilloma virus and due to a combination of HPV immunization and early detection with cervical cancer screening, advanced cervical cancer should be preventable. If it does occur, cervical cancer is one of the more treatable malignancies when detected early. If you perform cervical cancer screening for your patients, you know the guidelines have become a bit more complicated than in the past. To help us sort out who is a candidate for cervical cancer screening, when screening should start, how often it should be performed and when it can stop, we have as our guest for this podcast, Kathy L. MacLaughlin, M.D., a family physician in the Department of Family Medicine at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd
July 5, 2022
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Headache Edition: Migraine Advocacy & Special Considerations in Women

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Amaal J. Starling, M.D. (@AmaalStarlingMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Migraine is four-times more common in women than men and because of migraine predominance in females, it is a significant women’s health issue. Migraine commonly results in loss of productivity and this has a significant economic burden. According to a recent report from the Society for Women’s Health Research, it’s estimated that migraine costs the United States is an estimated $78 billion per year, with women accounting for approximately 80% of the direct medical and lost labor costs.  This podcast will continue our series on headaches and will concentrate on migraine in women. Our guest for this topic is Amaal J. Starling, M.D., a neurologist at the Mayo Clinic in Scottsdale, Arizona. We’ll discuss why migraine is more common in females, how the prevalence changes throughout a woman’s lifetime and specific treatment recommendations for women with migraine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 30, 2022
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Cannabidiol (CBD): Discussing Benefits and Risks with Patients

Guest: Thomas P. Pittelkow, D.O., M.P.H. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Cannabidiol (CBD) is a popular natural remedy used for a variety of common ailments and is one of more than 100 chemical compounds called cannabinoids derived from the cannabis plant. Tetrahydrocannabinol (THC) is the main psychoactive cannabinoid found in cannabis. However, unlike THC, CBD does not have psychoactive properties. There are claims this compound treats not only pain, but a variety of mental health issues, symptoms of malignancy and may even have some cardiovascular benefits. Are all these claims true? What’s been proven? What do we know about the safety of this product? We’ll get the answers to these questions as we discuss Cannabidiol (CBD) with Thomas P. Pittelkow, D.O., M.P.H., an anesthesiologist and pain medicine specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 28, 2022
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Headache Edition: Interdisciplinary Pain Rehabilitation Treatment for Chronic Headache

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Christopher D. Sletten, Ph.D., L.P. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Chronic headache is one of the more challenging medical conditions primary care providers commonly face. Whereas the traditional medical model views pain as a problem to be treated and relieved, this model often fails when dealing with patients experiencing chronic headaches. On the other hand, the bio-psychosocial model fits patients with chronic headache much better and when this model is used in the management, patients often have a much better outcome. This podcast is another in our series of headaches and will address the use of a cognitive-behavioral approach with an interdisciplinary team in the evaluation and management of patients with chronic headaches. Our guest Christopher D. Sletten, Ph.D., L.P., a psychologist at the Mayo Clinic in Jacksonville, Florida. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 23, 2022
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COVID-19 Update

This episode is shared from Mayo Clinic Q&A and was recorded in June 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) As immunity wanes for many vaccinated adults and omicron and its subvariants continue to circulate, it seems that just about everyone knows someone with a case of COVID-19. The steady increase in COVID-19 infections is due to changing, highly contagious variants, explains Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. Dr. Poland says it’s still important to take the precaution of mask-wearing in public areas, even if you have been vaccinated and have received your boosters. "I can’t say it enough. This is so hypercontagious that, regardless of having had three or four doses of vaccine or of having previous COVID-19, you still run an appreciable chance of getting COVID," explains Dr. Poland. "The risk in that case is not of death or hospitalization, but of the complications and long-haul symptoms of COVID-19. And that’s what we’re trying to prevent in people."  For parents, there is positive news this week, as the Food and Drug Administration (FDA) advisory panel voted unanimously to authorize emergency use of the Pfizer and Moderna COVID-19 vaccines for children under 5. For this age group, the Pfizer vaccine will be given in three doses while the Moderna vaccine will be given in two doses. The FDA panel's recommendation now goes to the Advisory Committee on Immunization Practices (ACIP) at the Centers for Disease Control and Prevention for approval before shots can be administered, possibly beginning as early as next week. On the Mayo Clinic Q&A podcast, Dr. Poland shares the latest COVID-19 news, answers listener questions, and discusses another infectious disease outbreak: monkeypox.  
June 22, 2022
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Assessing and Supporting Patients with Alcohol Use Disorder

Guest: Terry D. Schneekloth, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Unhealthy use of alcohol has the potential to affect not only the individual who consumes the alcohol, but a variety of others as well. Alcohol is the most used addictive substance, with an estimated prevalence of 7% of the United States population. Excessive alcohol use has the potential to cause damage to essentially every organ system and is thought to reduce one’s life expectance by approximately 10 years. Whereas treatment is available and has the potential to be very successful, it often requires an ongoing, lifetime of therapy. Our guest for this podcast is Terry D. Schneekloth, M.D., a psychiatrist and addiction medicine specialist at the Mayo Clinic in Scottsdale, Arizona. This podcast discusses when you should suspect alcoholism in your patients, how to make a diagnosis and which management techniques have been shown to be effective. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 21, 2022
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Headache Edition: Migraine Treatment

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Fred (Michael) M. Cutrer, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) It is estimated that nearly 40 million individuals in the United States have migraines and they’re responsible for a significant amount of lost productivity and healthcare costs. The estimates of the economic impact of migraines in the United States alone approaches $36 billion per year. Many of our patients struggle with adequate management of their migraines; healthcare providers are often confused about the many treatment options now available. This podcast will review and clarify the various treatments for migraines, both for abortive therapy as well as prevention. Our guest is Fred (Michael) M. Cutrer, M.D., a neurologist and headache specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 16, 2022
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Managing Patients with Lynch Syndrome

Guest: Eric J. Dozois, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) In the mid-1960’s Dr. Henry Lynch first described a condition characterized as the “cancer family syndrome” in which members of families demonstrated an increased risk of a variety of malignancies. This eventually became known as “Lynch Syndrome”. Lynch Syndrome is a genetic disorder and can be the underlying cause of premature colon cancer as well as other malignancies. There are some clues to its presence and specific recommendations for managing patients with the condition. The topic for this podcast is Lynch Syndrome and we’ll learn more about the disorder from our guest, Eric J. Dozois, M.D., a colorectal surgeon at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 14, 2022
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Headache Edition: Migraine

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Carrie (Beth) E. Robertson, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Migraine represents a major public health problem and is relatively common affecting an estimated 36 million individuals per year. It is much more likely to affect females and typically accounts for up to four million visits to the Emergency Department and over four million outpatient office visits per year. Migraines are most common in women of childbearing age and are associated with a significant loss of productivity, resulting in a major economic impact. In this podcast, we’ll continue our series on headache and will focus on migraine. We’ll review the diagnosis, what’s happening in the brain during a migraine attack and the benefits of lifestyle changes in the management of migraine. Our guest for this episode is Carrie (Beth) E. Robertson, M.D., a neurologist at the Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 9, 2022
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Headache Edition: Approach to the Evaluation of Headache

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Jerry W. Swanson, M.D., M.H.P.E. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Everyone has experienced a headache and for most of us, they are just a minor inconvenience. Unfortunately for some, headaches represent a major health problem. The pain can be intense and may result in major lifestyle changes including sudden change in plans, loss of productivity, and strained relationships. As primary care providers, patients with chronic, recurrent headaches can represent some of the most challenging patients we see. Fortunately, only rarely do headaches represent a serious threat to one’s life, but one still needs to be alert to potential clues indicating the possibility of the headaches representing a serious medical condition. There have also been numerous new treatments available for the management of migraines. This will be the first in a series of podcasts dedicated to the topic of headache. We’re also going to honor one of the Mayo Clinic’s most prestigious physicians in the field of headache. Jerry W. Swanson, M.D., M.H.P.E. has been a neurologist at Mayo for 39 years and has been a specialist in the evaluation and management of patients with headaches. He brings experience and a wealth of knowledge to this topic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 7, 2022
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Pediatric Topics: Evaluation of a Suspected Inborn Error of Metabolism

Guest: Brendan C. Lanpher, M.D. Host: David J. Sas, D.O. (@davidsas1) Inborn errors of metabolism can present in a variety of ways depending on the specific type of disease.  The most critical presentation to identify occurs in the neonatal period when more severe diseases can cause acute decompensation.  These patients require appropriate evaluation and timely, expert management for good outcomes.  Diagnostic testing, including newborn screening, is advancing rapidly as are innovative treatment methods, making this an exciting field for clinicians. The guest for this episode is Brendan C. Lanpher, M.D., a board-certified geneticist at the Mayo Clinic Children’s Center in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 2, 2022
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Women and Depression

Host: Joshua D. Luciew, MPAS, P.A.-C.    Guest: Neeta Jain, M.D. Depression is a common condition that we see in our practices. It is a multifactorial disease that can affect patients of all ages. In this episode, we discuss women and depression, as women are twice as likely as men to receive this diagnosis. We will explore how this condition is diagnosed, depression subtypes, what effect hormones have on a woman’s mental health, and how we can help treat this condition for our patients through various parts of their life. The guest for today’s episode is Neeta Jain, M.D., Mayo Clinic Board Certified Psychiatrist at Mayo Clinic in Arizona. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 31, 2022
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Pediatric Topics: Undescended Testicles – Evaluation and Management

Guest: Candace F. Granberg, M.D. (@candacegranberg) Host: David J. Sas, D.O. (@davidsas1) Detection and management of undescended testicles (cryptorchidism) is a common issue for newborn and infant boys.  This episode discusses proper diagnostic techniques for cryptorchidism, including how to distinguish between a retractile testicle and a truly undescended testicle, as well as when to refer infants to a pediatric urologist for further evaluation and management.  Further, we identify the indications for surgical correction and what parents and pediatricians should expect from this surgery. The guest for this episode is Candace F. Granberg, M.D., a board-certified pediatric urologist at the Mayo Clinic Children’s Center in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 26, 2022
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Adrenal Insufficiency: Investigation and Management

Guest: Irina Bancos, M.D. (@IrinaBancos) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Fatigue, weakness, and loss of appetite are very vague and non-specific symptoms, and unfortunately relatively common complaints our patients describe to us. However, they may also be the presenting symptoms of adrenal insufficiency. If untreated, serious complications can develop, the most serious being an adrenal crisis. Adrenal insufficiency is relatively uncommon and unless we think about it, we’re likely to either make a delayed diagnosis or possibly miss the disorder altogether. The topic for this podcast is adrenal insufficiency. We’ll review its symptoms, the recommended evaluation and management with Irina Bancos, M.D., an endocrinologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 24, 2022
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Mayo Clinic Q&A: COVID-19 news update

This episode is shared from Mayo Clinic Q&A and was recorded in May 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The widespread availability of at-home COVID-19 tests have made it easier for people to know if they have the virus, and to take measures to protect themselves and others. But there is a downside. Because the majority of tests are now done at home and often not reported, the official counts on COVID-19 infection rates are not as accurate as they have been in past waves of the virus.  "Because the majority of testing is being done at home, we can no longer tell you accurately about the positivity rate for a given community for a given state like we used to be able to," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "And this is problematic. It means that we lose our ability to understand what's called genetic epidemiology — the ability to trace how these variants are moving, how fast they're moving, and whether they're changing and evolving into yet different subvariants or new variants. We've lost that ability now." The most recent omicron subvariant, BA 2.12.1, has cases on the rise again and the U.S. passed a tragic milestone last week, reaching 1 million COVID-19 deaths in the country. In an effort to capture a more accurate picture, the latest tool being used by public health officials to track COVID-19 infection rates is wastewater surveillance. By looking for the presence of the COVID-19 virus shed by people, wastewater surveillance can give a more accurate picture of how much virus is in the community. This detects virus not only from those who test at home, but also from people who are asymptomatic and, therefore, didn't get tested. On the Mayo Clinic Q&A podcast, Dr. Poland discusses the current state of COVID-19 in the U.S., including what we know about the latest subvariants.
May 19, 2022
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Evaluating Adrenal Incidentalomas

Guest: Irina Bancos, M.D. (@IrinaBancos) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The widespread use of CT and MRI scans has resulted in frequent serendipitous findings, including adrenal nodules. When these nodules are found, two questions need to be answered. Is the nodule malignant and is this nodule metabolically active? This podcast will address these incidentally found adrenal nodules, also known as adrenal incidentalomas. We’ll review when these nodules should be investigated, the likelihood they represent a malignancy and how to assess if they’re metabolically active. Our guest for this podcast is Irina Bancos, M.D., an endocrinologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 17, 2022
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Eating Disorders Edition: Adult Eating Disorders

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest(s):   Scott Crow, M.D.; Carol B. Peterson, Ph.D., L.P. Host:  Jocelyn R. Lebow, Ph.D., L.P. While eating disorders are often thought of as disorders of adolescence, they impact adult patients across their lifespan. While many of the characteristics of these disorders are similar for pediatric vs. adult patients, there are important differences in how a primary care provider should assess and treat these illnesses in adults. As with younger patients, most adults report presenting initially to their primary care provider with their eating concerns, and many never seek additional care. This episode focuses on best practices for primary care providers in assessing and treating adult patients with eating disorders. Our guests are Scott Crow, M.D., Adjunct Professor of Psychiatry at the University of Minnesota and Vice President of Psychiatry at Accanto Health, and Carol B. Peterson, Ph.D., L.P., Clinical Psychologist and Professor in the Department of Psychiatry and Behavioral Sciences at the University of Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 12, 2022
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The Role of Monoclonal Antibodies in the Treatment of COVID-19

Guest: Raymund R. Razonable, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Monoclonal antibodies are laboratory-synthesized and mimic our immune system in fighting harmful pathogens. In addition to convalescent plasma and anti-viral medication, monoclonal antibodies have played an important role in the treatment of infections due to COVID-19. The use of monoclonal antibodies has been shown to shorten the duration of symptoms as well as reduce the risk of hospitalization and mortality due to COVID-19. This podcast will focus on monoclonal antibodies and our guest is Raymund R. Razonable, M.D., from the Division of Infectious Disease at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. Resource: O’Horo J, Challener DW, Anderson RJ, Arndt RF, Ausman SE, Hall ST, Heyliger A, Kennedy BD, Sweeten PW, Ganesh R, Razonable RR, Rates of Severe Outcomes After Bamlanivimab-Etesevimab and Casirivimab-Imdevimab Treatment of High-Risk Patients With Mild to Moderate Coronavirus Disease-2019, Mayo Clinic Proceedings (2022), doi: https://doi.org/10.1016/j.mayocp.2022.02.009.
May 10, 2022
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Mayo Clinic Q&A: COVID-19 news update

This episode is shared from Mayo Clinic Q&A and was recorded in April 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) An estimated 3 out of 4 U.S. children and more than half of all adults have been infected with COVID-19, according to a report released on Tuesday, April 26 by the Centers for Disease Control and Prevention. But a Mayo Clinic expert says more information is needed to get the complete picture. "This was a convenient sample. In other words, people who were having blood drawn for other reasons were tested,"explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "That does not reflect the full population or differences by race or geographic location. And the detection of antibodies does not necessarily mean that you are protected from infection. So, there's a lot of nuance around understanding that headline." The research study looked at more than 200,000 blood samples and found that signs of past infection rose dramatically during the omicron surge between December 2021 and February. Other COVID-19 news this week includes a push to make treatments more available, the rising incidence of new omicron subvariants, and changes in mask recommendations. Dr. Poland cautions that COVID-19 is still present and encourages wearing a mask in crowded spaces, even when there isn't a requirement to do so. "If only one of us is wearing a mask and the other one isn't and is infected, you still have pretty high protection — but not the same level of protection as if both of us wearing one," says Dr. Poland. "So, it's it is not futile to be the only one wearing a mask. In fact, I think it sends a message." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news and answers listener questions.
May 6, 2022
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Eating Disorders Edition: Case Discussions

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guests:  Angela C. Mattke, M.D. (@DrAngelaMattke); Paige I. Partain, M.D. Host:  Jocelyn R. Lebow, Ph.D., L.P. Though the Diagnostic and Statistical Manual of Mental Disorders (DSM–5) is clear in classifying eating disorders, clinicians understand it is rare to be presented with a straightforward case. Patients present with comorbidities and family circumstances that muddy the clinical picture and the treatment plan. This case-based episode focuses on how primary care providers can treat children with eating disorders. This episode will examine complicated eating disorder cases, featuring guests Angela C. Mattke, M.D. and Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatricians, and colleagues and collaborators in the primary care child and adolescent eating disorder clinic at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 5, 2022
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Fragility Fractures

Guest: Ann E. Kearns, M.D., Ph.D.          Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) It is estimated that worldwide, one in three women, and one in five men over the age of 50 will experience osteoporosis fractures during their lifetimes. In this podcast, we discuss risk factors and management of fragility fractures and bone health with Ann E. Kearns, M.D., Ph.D., a Consultant Endocrinologist and Associate Professor within the Department of Medicine at Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 3, 2022
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Eating Disorders Edition: Basic Principles of Treatment for the Primary Care Provider

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guests:  Angela C. Mattke, M.D. (@DrAngelaMattke); Paige I. Partain, M.D. Host:  Jocelyn R. Lebow, Ph.D., L.P. We understand eating disorders are serious and evidence-based Family Based Treatment (FBT) is scarce but effective. This episode will discuss strategies informed by evidence based FBT principles that can be used by providers in primary care settings to address eating disorder symptoms. Though typically the responsibilities of primary care providers in eating disorder treatment are limited to case identification, referral, and medical management, these providers have vast experience empowering caregivers to help their children change behavior.  Equipping primary care providers to deliver evidence-based treatment for restrictive eating disorders has the potential to expand access to early intervention and improve outcomes. Our guests for this episode are Angela C. Mattke, M.D. and Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatricians, and colleagues and collaborators in the primary care child and adolescent eating disorder clinic at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
April 28, 2022
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The Use of Race in Clinical Algorithms

Guest: Ramla N. Kasozi, M.B., Ch.B., M.P.H. Host: Darryl S. Chutka, M.D. (@ChutkaMD) There is currently a debate regarding the use of race and ethnic categories in clinical decision-making. There are numerous studies which claim data from race is a factor and should be considered when designing practice guidelines and clinical algorithms. Some feel that any benefit is small compared to the potential harm that could occur regarding the past abuse of race used in medicine. Unfortunately, many questions remain unanswered. Is race a reliable proxy for genetic differences? Are there genetic differences which explain the basis behind race-based algorithms? And what are the potential dangers of using race-adjusted algorithms? This podcast reviews these topics with Ramla N. Kasozi, M.B., Ch.B., M.P.H., a family physician at the Mayo Clinic in Jacksonville, Florida. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 26, 2022
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Eating Disorders Edition: Treatment for Eating Disorders

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest(s):  Jocelyn R. Lebow, Ph.D., L.P. Host:  Angela C. Mattke, M.D. (@DrAngelaMattke) Eating disorders impact an estimated 3-15% of adolescents and, if left untreated, or only partially treated, can become chronic conditions. Relapse is also common in eating disorders with over 40% of patients reporting at least one relapse in some studies. Despite these sobering statistics, when adolescent patients complete a course of good, evidence-based treatment, they can expect to make and maintain a full recovery from their symptoms. Primary care providers play a critical role in helping patients and their families find care and determine whether the care they’re getting is having the right effect. This episode will concentrate on different types of eating disorder treatment: what’s out there and what the evidence says works best. Our guest is Jocelyn R. Lebow, Ph.D., L.P., a Mayo Clinic child and adolescent psychologist and collaborator in the Mayo Clinic primary care child and adolescent eating disorder clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 21, 2022
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Secondary Hypertension: Identifying Clues in Patients

Guest: Sandra J. Taler, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD)  Nearly half of all adults in the United States have some degree of hypertension and it’s one of the most common reasons patients are seen in an outpatient practice. The vast majority have essential or primary hypertension and they usually respond to a combination of lifestyle changes and often pharmacologic therapy. A small percentage of these cases have secondary hypertension and often do not respond to treatment unless the underlying cause is found and corrected. At times, it can be difficult to identify the cause of secondary hypertension as the clues may be quite subtle or even non-existent. Our guest for today’s podcast is Sandra J. Taler, M.D. from the Division of Nephrology and a hypertension specialist from the Mayo Clinic. We’ll discuss when you should suspect secondary hypertension, the clues the patient may give us regarding its cause and its management. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 19, 2022
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Eating Disorders Edition: Medical Management of Eating Disorders in Primary Care

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guests:  Marcie L. Billings, M.D.; Paige I. Partain, M.D. Host:  Angela C. Mattke, M.D. (@DrAngelaMattke) The medical evaluation for eating disorders is very important. It is the primary care provider’s role to rule out other causes of weight loss, especially when eating disorder signs might not be as apparent at the beginning or the patient isn’t entirely forthcoming. Additionally, the patient and their family have an inherent trust in a primary care provider as their long-term medical provider. This episode will focus on the medical evaluation and management of eating disorders – what vital signs are significant, what labs are necessary including how often they should be performed, how frequently patients need to be seen in collaboration with their therapist, and how to determine if a patient is medically unstable and needing immediate admission for monitoring and treatment. The guests for this episode are Marcie L. Billings, M.D. and Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatricians, and colleagues and collaborators in the primary care child and adolescent eating disorder clinic at Mayo Clinic.  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 14, 2022
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Treating Hypertension: Doing What’s Best for Your Patient

Guest: Ivan E. Porter, II M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Nearly half of all adults in the United States have hypertension and it’s one of the most common reasons for an outpatient visit. Despite this, it’s estimated that only about a fourth of those diagnosed with hypertension are adequately controlled and about 20% of adults with hypertension are unaware that they even have it. Since uncontrolled hypertension can increase the risk of cerebral, cardiac and renal events, it’s important to make an accurate diagnosis and appropriately manage patients with the condition. The topic for this podcast is hypertension and we’ll discuss the changes in blood pressure with aging, the definition of hypertension, the proper technique of checking blood pressure and helpful management techniques with today’s guest, Ivan E. Porter, II M.D., a nephrologist and hypertension specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 12, 2022
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Eating Disorders Edition: Identification and Assessment of Eating Disorders for the Primary Care Provider

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest:  Paige I. Partain, M.D. Host:  Jocelyn R. Lebow, Ph.D., L.P. Child and adolescent eating disorders are serious diseases, characterized by a range of physical and psychological consequences. They are often associated with a chronic course and numerous relapses. This episode focuses on how primary care providers can assess for and identify eating disorders in child and adolescent patients. We will discuss high yield assessment questions and tools that you can use in your primary care practice when you suspect a young patient may meet the criteria for an eating disorder. Our guest is Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatrician and collaborator in the primary care child and adolescent eating disorder clinic at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 7, 2022
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Eating Disorders Edition: Eating Disorders 101: Background and Debunking Myths

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest:  Jocelyn R. Lebow, Ph.D., L.P. Host:  Angela C. Mattke, M.D. (@DrAngelaMattke) Eating disorders are a huge problem in our country. Whether realizing it or not, primary care providers who treat teenagers are likely caring for patients with eating disorders.  Though estimates vary, approximately 3-15% of adolescents will experience an eating disorder. Along with the numerous physical and psychological consequences of these illnesses, eating disorders also have the second-highest mortality rate of any mental illness: one in five patients will die from complications related to their eating disorder.  This episode is the first episode in our Eating Disorders edition, which focuses on how primary care providers may treat children with eating disorders. This episode will concentrate on the basics: what are eating disorders, what do they do to our patients, and what myths and misunderstandings exist that hinder effective identification and treatment. Our guest is Jocelyn R. Lebow, Ph.D., L.P., a Mayo Clinic child and adolescent psychologist, and collaborator in the Mayo Clinic primary care child and adolescent eating disorder clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 5, 2022
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Mayo Clinic Q&A: COVID-19 metrics improve, expert still urges caution

This episode is shared from Mayo Clinic Q&A and was recorded in March 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Hospitalizations and deaths due to COVID-19 continue to decline, leading to some optimism about the way forward from pandemic to endemic. But experts still urge caution as the omicron subvariant, named BA.2, has quickly become the dominant strain in the U.S. "When you look around the nation, all of the metrics, with the exception of BA.2, have fallen precipitously," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "But we need to be very cautious about pretending that the pandemic is over." Dr. Poland explains that each time there has been a waning number of COVID-19 infections, people have let down their guard and relaxed precautions, which has led to another surge. Dr. Poland still recommends masking in crowded indoor settings and urges people to be fully vaccinated and boosted against COVID-19 to reduce the chance of infection. "We're just coming down into a quiet period," says Dr. Poland. "But every time we've seen this set of markers in the past, we've had a new variant that's caused a surge. The question is, will it be BA.2, one of the newer variants that have been identified, or something completely unexpected? We just don't know." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news including potential changes to booster recommendations, data on vaccine protection for pregnant women, and the latest information on COVID-19 vaccines for children under 5.  
March 31, 2022
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Colorectal Cancer – Screening Guidelines Updates

Guest: John B. Kisiel, M.D. (@DrJohnKisiel) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Colorectal cancer is the third most commonly occurring cancer for both men and women and ranks second to lung cancer as a cause of cancer mortality. Yet it’s estimated that up to one quarter of eligible adults in the United States have never been screened for colorectal cancer and nearly one third are not up to date with their screening. We now have a variety of accepted screening tests for colorectal cancer and each carries its own risks and benefits. This podcast will review colorectal cancer screening, including when we should start screening, the various available screening tests, as well as their advantages and limitations. Our guest for this episode is gastroenterologist, Dr. John Kisiel from the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 29, 2022
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Post COVID Syndrome

Guest: Greg Vanichkachorn, M.D., M.P.H. (@DoctorGregVan) Host: Darryl S. Chutka, M.D. (@ChutkaMD) While most patients who have COVID-19 completely recover within a few weeks, there are some patients who continue to experience symptoms that can last for months. These patients may require our care for an extended period of time.  Although much has been learned about COVID-19 over the past couple of years, there is still a great deal that’s not known. The topic for this podcast is post-COVID syndrome and our guest is Greg Vanichkachorn, M.D., M.P.H., a preventive medicine physician and specialist in Public Health. We’ll discuss the typical symptoms, duration of symptoms, and who is most likely to develop post-COVID syndrome. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 22, 2022
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Mayo Clinic Q&A: COVID-19 Update

This episode is shared from Mayo Clinic Q&A and was recorded in March 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Last week marked two years since the World Health Organization declared COVID-19 to be a pandemic. While infection rates and hospitalizations in the U.S. continue to decline, there are some areas of concern globally. "China, Hong Kong, Ireland, the U.K. and Denmark are seeing surges back up again," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "These countries, many of us experts believe, prematurely dropped mask-wearing and nonpharmaceutical interventions, and really have stopped pushing and encouraging people to get vaccinated. I think that's a mistake." Dr. Poland explains that public health measures — and vaccination and boosters — are still the best way to protect yourself from COVID-19. "What can I say but what we have said all along," implores Dr. Poland. "Hands, face, space and vaccines. It works." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news, including a study on the true death toll of COVID-19, an update on the BA.2 variant and the latest on vaccines for children under 5.
March 17, 2022
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Skin Cancer and Skin Lesions: What to Look For

Guest: Dawn Marie R. Davis, M.D. Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) Did you know that skin cancer is the number one cancer in the United States, with an estimated 3.5 million cases a year? In fact, your lifetime incidence is 1 in 5, or 20%. In this week’s podcast, Dawn Marie R. Davis, M.D., a Pediatric and Adult Dermatologist at Mayo Clinic in Rochester, Minnesota, discusses all things skin cancer. She provides tips and tricks in the management of common forms of skin cancer that providers need to be aware of when patients present with skin lesions. Dr. Davis also discusses the role of skin-protecting creams and their applicability to persons of all skin colors. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
March 15, 2022
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Mild Cognitive Impairment, Dementia, and Alzheimer’s Disease

Guest: Ronald C. Petersen, M.D., Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Nearly six million people in the United States age 65 and older have Alzheimer’s Disease; of these about 80% are 75 years old and older. It is a devastating disease, not only for the patient, but also for the family of the patient involved. Unfortunately, currently available treatment for Alzheimer’s has been disappointing. Cure or even stability of the cognitive loss is not possible. The topics for today’s podcast include mild cognitive impairment and dementia, focusing on Alzheimer’s Disease, and our guest is Ronald C. Petersen, M.D., a Mayo Clinic neurologist and specialist in Alzheimer’s Disease and other dementias. We’ll discuss the evaluation, the current available treatment as well as what might be on the horizon in the management of this disease. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 8, 2022
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Heart Disease in Women

Guest: Sharonne N. Hayes, M.D. (@SharonneHayes) Host: Darryl S. Chutka, M.D. (@ChutkaMD)   Cardiovascular disease remains the leading cause of death for individuals in the United States. Many assume this is primarily a disease of men, but it also continues to be the leading cause of mortality in women, accounting for one of every three female deaths. There’s also evidence that symptoms of cardiovascular disease may be somewhat different than in males. As a result, women are often given a different evaluation and may receive different treatment than males. To help us sort this out, our guest for this podcast is Sharonne N. Hayes, M.D., a cardiologist and specialist in women’s heart disease from the Mayo Clinic. We’ll discuss the misconceptions of cardiovascular disease in women, the variety of symptoms they may develop and treatment considerations that may be different than men typically receive. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
March 1, 2022
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Amyloidosis: Recognition, Diagnosis and Treatment

Guest: Eli Muchtar, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Amyloidosis is an uncommon disease, possibly even considered rare. It has a variety of presentations and some varieties tend to occur in association with other diseases. The presenting symptoms depend on the organ system involved. Unless we think of the condition, we may miss the opportunity to diagnose it early. As a result, many patients are diagnosed with amyloidosis at a rather advanced stage. The topic for this podcast is amyloidosis and our guest is Eli Muchtar, M.D., from the Division of Hematology at the Mayo Clinic. We’ll discuss the common organ systems affected by amyloidosis, how it’s diagnosed, the available treatment and the research currently taking place in amyloidosis. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 22, 2022
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Mayo Clinic Q&A: COVID-19 News Update

This episode is shared from Mayo Clinic Q&A and was recorded in February 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) As the U.S. moves beyond the omicron surge of the COVID-19 pandemic, key indicators are dropping. "Both the acute indicators — number of cases — and the lagging indicators — hospitalizations and then deaths — are all dropping slowly, but they're surely dropping," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.  Experts warn that caution is still needed to protect yourself in certain situations, including masking in crowded indoor settings and making sure you are up to date with your COVID-19 vaccinations and boosters. While the latest surge wanes, COVID-19 research continues.  On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news, including a new study on the long-term effects of COVID-19 on the heart and why Pfizer is delaying the request for emergency use authorization of its COVID-19 vaccine for children under 5.
February 17, 2022
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Infertility in Males

Guest: Sevann Helo, M.D. (@Helo_MD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Approximately one in seven couples is considered infertile. In a significant number of these couples, male infertility plays a role. Many of these couples will initially present to their primary care provider for help. Depending on our practice, we may not see all that many patients with this concern and, as a result, we might not be comfortable with the evaluation of the infertile couple. Today’s podcast will review infertility in males and hopefully give us a better understanding of the causes of infertility and how to evaluate the infertile male. Our guest for today’s podcast is Sevann Helo, M.D., a urologist at the Mayo Clinic. We’ll discuss what it takes for fertilization to take place, risk factors for infertility in males, the evaluation of the male for infertility, potential treatment options and effectiveness of treatment. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 15, 2022
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Dental Infections in the Primary Care Setting

Guest: Olivia (Liv) M. Muller, D.D.S. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Dental caries and periodontal disease are commonly seen by primary care providers in the outpatient setting. In fact, dental caries is the most common disease in the United States, both in children and adults. Up to 50% of children have dental caries, and most adults have at least one tooth with decay or have a filling. Gingivitis is also quite common in adults; it is present in up to half of all individuals between the ages of 35 and 45. Yet, unless we go into dentistry, healthcare providers don’t get much training in the evaluation of dental conditions. The topic of discussion for this podcast is dental care and dental infections. Our guest is Olivia (Liv) M. Muller, D.D.S., an Assistant Professor of Dentistry at the Mayo Clinic. We’ll discuss which dental problems we’re likely to encounter in our patients, recommendations we can give them to prevent dental infections and some of the more common complications of dental infections. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 8, 2022
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Mayo Clinic Q&A: Omicron wave wanes, new variant arises

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The number of new COVID-19 cases in the U.S. is dropping as the omicron wave wanes in many places, but some parts of the country lag behind. "As a nation, it looks like we've kind of gotten to the peak and are now starting on the decline, but it's very uneven," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "That's what's happening in the big Northeast cities, and maybe in L.A., for example. But if you look at the rest of the nation, it's not clear that they have peaked yet." And on the heels of the latest surge, a new omicron subvariant — BA.2 — is emerging. Early indications are that the new subvariant may be more transmissible, but it does not appear to cause more severe disease than the original omicron strain. Mayo experts, including Dr. Poland, continue to urge COVID-19 vaccinations and boosters as the best defense against the latest variants.  "By getting two doses of vaccine and a booster, or a dose of Johnson & Johnson and a booster, you move yourself into a category of maximal protection such that if you have a normal immune system, you are probably going to have trivial or even asymptomatic disease if you get infected with COVID-19," explains Dr. Poland.  On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest information on COVID-19 and answers listener questions.
February 3, 2022
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Shining a Light on Seasonal Affective Disorder

Guest: Craig N. Sawchuk, Ph.D., L.P. Host: Darryl S. Chutka, M.D. (@ChutkaMD) It is quite common for individuals to go through periods where they feel somewhat sad and discouraged and often these mood changes tend to occur with the changes in seasons, especially during the winter months. In some cases, these mood changes become more serious and can result in depression. When people experience depressive episodes in the late fall and winter, this may represent Seasonal Affective Disorder. Our guest today is Craig N. Sawchuk, Ph.D., L.P., a psychologist in the Department of Psychiatry & Psychology at the Mayo Clinic. Our topic for this podcast is Seasonal Affective Disorder. We’ll discuss its frequency, how we can recognize it in our patients, and the available treatment options. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 1, 2022
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Mayo Clinic Q&A: COVID-19 testing scenarios — what test and when?

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Matthew J. Binnicker, Ph.D. (@DrMattBinnicker) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Testing for COVID-19 is a part of the strategy to end the pandemic. But understanding testing — different types of tests and how and when to use them — can be confusing. Lab-run polymerase chain reaction, or PCR, tests and at-home antigen tests each have a role. "PCR tests are really sensitive, meaning we can detect really low levels of the virus in a sample," explains Dr. Matthew Binnicker, director of Clinical Virology at Mayo Clinic. "They're very specific, meaning we shouldn't get many false positive results with PCR tests." At-home antigen tests use a nasal swab and can produce results in 15 minutes, but they also have an increased chance of false-negative results, depending on when you test.  "At-home rapid antigen tests look for a viral protein in the patient sample," says Dr. Binnicker. "So they're quick and easy, but they also have some important limitations." So if you're worried you might have COVID-19, what test should you take and when?  On the Q&A podcast, Dr. Binnicker walks through various scenarios and makes testing recommendations for what to do if: You think you’ve been exposed but I don’t have symptoms. You have symptoms of COVID-19. You had COVID-19 and want to know if you're “in the clear” to return to work, school or activities.
January 27, 2022
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Chiropractic Care for Back Pain

Guest: Benjamin (Ben) D. Holmes, D.C., Ph.D. Host: Edward R. Laskowski, M.D. (@DrEdSportsMed) Low back pain is one of the most common conditions that physicians see in their practices. Studies indicate that, by the age of 50 years old, approximately 80% of people will experience low back pain in their lives. Joining us today is Benjamin D. Holmes, D.C., Ph.D. a practicing chiropractor and one of the spine specialists in the Mayo Clinic Spine Center. Dr. Holmes will discuss various treatment interventions for back pain, as well as misconceptions and assumptions regarding chiropractic treatment. Additional Resources: Foster, N. E., Anema, J. R., Cherkin, D., Chou, R., Cohen, S. P., Gross, D. P., ... & Woolf, A. (2018). Prevention and treatment of low back pain: evidence, challenges, and promising directions. The Lancet, 391(10137), 2368-2383. Bialosky, J. E., George, S. Z., Horn, M. E., Price, D. D., Staud, R., & Robinson, M. E. (2014). Spinal manipulative therapy–specific changes in pain sensitivity in individuals with low back pain (NCT01168999). The Journal of Pain, 15(2), 136-148. Cook, C., Learman, K., Showalter, C., Kabbaz, V., & O'Halloran, B. (2013). Early use of thrust manipulation versus non-thrust manipulation: a randomized clinical trial. Manual Therapy, 18(3), 191-198. Chou, R., Fu, R., Carrino, J. A., & Deyo, R. A. (2009). Imaging strategies for low-back pain: systematic review and meta-analysis. The Lancet, 373(9662), 463-472. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 25, 2022
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Mayo Clinic Q&A: Why getting infected with COVID-19 is still a bad idea

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) With the highly transmissible omicron variant spread across the U.S., it may seem inevitable that most people will get infected with COVID-19. But Mayo Clinic experts explain why it is important to continue to be vigilant and take measures to avoid COVID-19 infection.  "One of the many negatives about saying, 'Well, I'll just go ahead and get infected and get it over with' is you can spread the virus to highly vulnerable people," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "Parents, grandparents, people too young to be immunized, and people whose immune systems might not be working well are all at risk of more severe disease. While your case may be mild, theirs may not."  Dr. Poland cautions that the sheer number of infections is stressing the health care system, and treatments for omicron are more limited than they were for the delta variant. "The role of testing and of getting boosted is critical to our response to this, and remember, even though you might have mild disease, every time this virus infects somebody, it is the opportunity for further mutation." says Dr. Poland.  Vaccination, boosting and masking are all necessary to prevent the spread of omicron. "Your best chance of protecting yourself is to be fully vaccinated, wear a proper mask properly when in public, and to avoid crowded indoor settings," says Dr. Poland. On the Mayo Clinic Q&A podcast, Dr. Poland discusses the omicron surge and answers listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 20, 2022
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Improving Medication Adherence

Guest: Kristina M. Thurber, Pharm.D., R.Ph. Host: Darryl S. Chutka, M.D. (@ChutkaMD) There are a variety of outstanding pharmaceutical products we use to treat the multiple health problems our patients develop and every year, clinical research has provided us with new and improved therapeutic options. When we prescribe a medication to a patient, we generally assume they’ll take it exactly as prescribed. Unfortunately, that’s not necessarily true. Non-adherence to chronic medications is surprisingly common and can account for up to half of all treatment failures. Our guest for this podcast is Kristina M. Thurber, Pharm.D., R.Ph., a medication therapy pharmacist at the Mayo Clinic. We’ll discuss the prevalence of medication adherence, its causes, how we can recognize it in our patients and management strategies to improve adherence. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 18, 2022
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All Age-Related Changes May Not Be Inevitable: Senescent Cells and Anti-Aging

Guest: Nathan K. LeBrasseur, Ph.D., M.S. (@NKLeBRASSEUR) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The effects of aging occur in all our organs. In muscles, there is a reduction in strength and stamina; the brain shows a decrease in cognitive function and the ability to learn new information. Aging causes a reduced ability of the liver to metabolize drugs and the kidney’s ability to eliminate various waste products. Our guest for this podcast is aging researcher Nathan K. LeBrasseur, Ph.D., M.S., the senior author of a study recently published in the journal “Aging Cell.” The authors described significant benefits from exercise on a cellular level which correlated with an improvement in physical changes related to aging. We’ll discuss cellular changes which occur with aging, the significance of senescent cells and how exercise can reduce the impact of aging on both a cellular level as well as clinically. Specific topics: The effects of aging on a cellular level Variability in the rate of aging in individuals Function of senescent cells Effects of exercise on senescent cells Clinical correlations resulting from the elimination of senescent cells Recommendations clinicians can give their patients to reduce the effects of aging
January 11, 2022
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Mayo Clinic Q&A: January Bringing an Omicron Surge

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The rapid spread of COVID-19 due to the omicron variant continues, and experts expect a January surge across the U.S.  "This is spreading unlike anything we've seen in the U.S.," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.  "Over the last seven days, we're now averaging about 400,000 or so new cases a day." While people who are fully vaccinated can get breakthrough infections and spread the virus to others, COVID-19 vaccines effectively prevent severe illness. Mayo Clinic experts urge people to protect themselves by getting vaccinated and wearing a mask. Being fully vaccinated, including getting a booster when eligible, offers the highest protection possible against COVID-19.  "The good news is, for those who are immunized and boosted, we are winning the battle," says Dr. Poland. "Getting immunized is basically a weapon against this virus." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the omicron surge and the importance of vaccines and boosters for COVID-19. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 6, 2022
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Temporal Arteritis

Guest: Andy Abril, M.D. (@andyabrilMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Temporal arteritis is a vasculitis involving medium-sized vessels and typically occurs in those over the age of 50. If diagnosed and treated early, there is an excellent likelihood of recovery. However, temporal arteritis often mimics other health problems and this commonly results in a delay in the diagnosis. If untreated, serious complications can occur, including permanent blindness or stroke. The topic for this podcast is temporal arteritis and our guest is Andy Abril, M.D., Chair of the Division of Rheumatology at the Mayo Clinic in Jacksonville, Florida. We’ll discuss the risk factors, presenting symptoms and complications of temporal arteritis, as well as the recommendations for establishing a diagnosis and initiating appropriate treatment. Specific topics discussed: Risk factors for temporal arteritis Presenting symptoms Complications of untreated temporal arteritis Extra-cranial artery involvement of patients with temporal arteritis Relationship of temporal arteritis and polymyalgia rheumatica Laboratory abnormalities in temporal arteritis Importance of an early temporal artery biopsy in establishing a diagnosis Treatment recommendations Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 4, 2022
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Nutritional Supplement Edition: Research and Regulation

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, PhD Host: Darryl S. Chutka, M.D. (@ChutkaMD) How can we tell if the claims made by nutritional supplement companies are factual?  In this episode we'll discuss the research currently being done in this field and whether the research findings are valid.  Finally, we’ll talk about regulation of nutritional supplements. Our guest for this podcast is Andrew R. Jagim, Ph.D., the director of Sports Medicine research at the Mayo Clinic. Specific topics: Importance of a foundation of good nutrition and exercise related to the benefits of nutritional supplements Amount and quality of research being done on nutritional supplements Regulation of nutritional supplements How healthcare providers and consumers can judge the many claims made by manufactures of nutritional supplements
December 30, 2021
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Lung Cancer Screening

Guest: Sebastian Fernandez-Bussy, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Lung cancer is the second most common malignancy in both men and women.  Survival rates depend on how early the cancer is discovered, with a survival rate much higher in localized disease than for patients with distant metastases. Therefore, an early diagnosis becomes extremely important. One of the problems with early diagnosis is that until recently, we’ve not had an effective screening test for lung cancer. In this podcast, we’ll be speaking with Sebastian Fernandez-Bussy, M.D., an Interventional Pulmonologist from the Division of Pulmonary and Critical Care at the Mayo Clinic in Jacksonville, Florida, and we’ll discuss proven techniques for lung cancer screening. Specific topics: Benefits in survival in finding lung cancer at an early stage Candidates for screening patients at an increased risk for lung cancer Evidence showing the benefits of lung cancer screening Differences in radiation for chest CT scans used for screening vs. a typical diagnostic chest CT scan Frequency of indeterminate pulmonary nodules found on chest CT Insurance and Medicare coverage for lung cancer screening Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 28, 2021
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Nutritional Supplements Edition: Family Medicine Case Studies

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guests: Andrew R. Jagim, Ph.D. Jakob R. Erickson, D.O. Host: Darryl S. Chutka, M.D. (@ChutkaMD) The care of athletes often requires special knowledge that many healthcare providers are less familiar with.  Athletes may have somewhat unique health problems related to their endurance or strength training.  They may also be taking a variety of nutritional supplements which could cause health issues.  This case-based podcast covers a couple different examples of health issues experienced by athletes. Featured guests include Andrew R. Jagim, Ph.D. and Jacob R. Erickson, D.O. from Sports Medicine at Mayo Clinic. We’ll discuss some of the medical issues often faced by athletes. Specific topics: Iron-deficiency anemia Relative Energy Deficiency in Sport Vitamin D deficiency and hypervitaminosis D Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 23, 2021
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Infertility in Females

Guest: Elizabeth A. Stewart, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Infertility can be related to health issues in the male, female or both. Whatever the reason, infertility can put a major strain on a couple’s relationship. To add to the stress, infertility often results in multiple exams, tests, injections and procedures for one or both of the couple. Fortunately, the cause of infertility can often be found and in some cases, treatment is effective, resulting in a successful pregnancy and birth. The topic of discussion for this podcast is infertility, specifically infertility in females. Our guest is Dr. Elizabeth (Ebbie) A. Stewart, a physician in the Department of Obstetrics and Gynecology and Division of Endocrinology and Infertility. We’ll review the prevalence of infertility in females, males and both, risk factors for infertility, the most common causes of infertility and the evaluation a primary care provider can perform. Specific topics discussed: Definition of infertility Prevalence of infertility Risk factors for infertility Recommended evaluation by primary care providers Specialized evaluation performed by an infertility expert Common causes of infertility in females Success of infertility treatment Invitro fertilization as a treatment alternative to infertility including cost, success rate and risk of multiple births Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 21, 2021
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Mayo Clinic Q&A: Experts urge COVID-19 boosters to fight omicron surge

This episode is shared from Mayo Clinic Q&A and was recorded in December 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) More Americans are now eligible for COVID-19 booster doses as the Centers for Disease Control and Prevention approved the Pfizer vaccine booster for 16- and 17-year-olds late last week. Previously, only those 18 and older were eligible. Early research suggests that a booster dose of the Pfizer COVID-19 vaccine improves protection against severe disease caused by the omicron variant, according to Pfizer. Mayo Clinic experts say, regardless of the variant, prevention of infection works. Getting a booster offers the highest protection possible against COVID-19. "Omicron infection rates are picking up rapidly," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "If we do not take the proper precaution over the holiday, we are going to see a January omicron surge." Dr. Poland explains that there are two threats — delta and omicron COVID-19 variants — but there is a solution. "Masking and boosting — those are key to protecting yourself and your family." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest on COVID-19 variants and shares advice on how to stay safe this holiday season. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 17, 2021
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Nutritional Supplement Edition: Weight Loss and Thermogenic Agents

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Are there supplements available that really assist with weight loss? How can you help your patients navigate the market? What is safe and what do they need to look out for? Andrew R. Jagim, Ph.D., the director for Sports Medicine research at the Mayo Clinic, answers these questions in this episode.  We discuss the importance of diet and exercise in weight loss and the benefits nutritional supplements may add.  We also discuss some of the more common supplements promoted to enhance thermogenesis and weight loss as well as their proposed mechanism of action. Specific topics: Popular nutritional supplements for enhancing weight loss Accuracy of claims for nutritional supplements Importance of diet and exercise in producing significant weight loss Potential benefits of a nutritional supplement in addition to exercise and diet in producing significant weight loss Common supplements promoted to enhance weight loss
December 16, 2021
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Influenza Vaccine 2021

Guest: Robert M. Jacobson, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Preventing influenza is important for a variety of reasons. Influenza is not a benign illness. In recent years, it’s accounted for up to 700,000 hospitalizations and over 50,000 deaths annually. The vaccine not only saves lives but also helps prevent hospitalizations as well as the need for the ICU. The occupancy rates of both have been severely stressed due to COVID. Despite the fact that the vaccine has been shown to be effective in all age groups, a significant percent of the population do not receive it. This podcast will discuss the influenza vaccine, it’s overall effectiveness in preventing the illness, the optimal time of year to receive the vaccine and tips on how to increase the likelihood that our patients will agree to receive it. Our guest is Dr. Robert M. Jacobson, a pediatrician and immunization expert at the Mayo Clinic. Specific topics: Possible impact on the susceptibility or severity of influenza for the 2021/2022 season given there was such a reduction in influenza cases last year The time of year the vaccine for the current influenza season is released The optimal time of year to receive the influenza vaccine The effectiveness of the influenza vaccine in preventing the illness The likelihood we’ll see testing for both COVID and influenza increase this winter Tips on increasing the number of patients who agree to receive the influenza vaccine Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 14, 2021
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Mayo Clinic Q&A: Post COVID-19 syndrome can be a long haul

This episode is shared from Mayo Clinic Q&A and was recorded in December 2021 Guest:  Greg Vanichkachorn, M.D., M.P.H. (@DoctorGregVan) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Most people who have COVID-19 recover completely within a few weeks. But some people — even those who had mild versions of the disease — continue to experience symptoms after their initial recovery.  Sometimes called “long haulers” or “long COVID," these patients can have fatigue, shortness of breath, brain fog and other symptoms long after the time of their infection. Post-COVID-19 syndrome conditions are generally considered to be effects of COVID-19 that persist for more than four weeks after you've been diagnosed with COVID-19 infection. A recent Mayo Clinic study on post-COVID-19 symptoms found that more women than men suffer long-term effects. Women predominantly showed symptoms of fatigue, followed by muscle pain and low blood pressure, while men primarily experienced shortness of breath. Research is also underway to better understand what may be causing post-COVID-19 syndrome. "We do have some research now that shows that some of the cells that are used to create immunity after an infection, they may be malfunctioning in this condition in patients with long-haul COVID," says  Dr. Greg Vanichkachorn, director of Mayo Clinic’s COVID Activity Rehabilitation Program. "We also now have some research that shows that patients with this condition can have antibodies against themselves, otherwise known as an auto-antibody. And this may be associated with the long-haul COVID state, so immune dysfunction and auto immunity, they may be at play here." The COVID Activity Rehabilitation Program at Mayo Clinic helps people experiencing post-COVID-19 syndrome by working with patients to decrease symptoms and improve overall functioning and quality of life.  On the Mayo Clinic Q&A podcast, Dr. Vanichkachorn discusses how treatment can help patients who suffer from post-COVID-19 syndrome. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 10, 2021
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Nutritional Supplements Edition: Strength, Power, and Performance

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Nutritional supplements are being promoted to enhance a variety of areas of physical fitness. This episode focuses on the impact on strength, power and overall performance. Our guest for this podcast is Andrew R. Jagim, Ph.D., the director of Sports Medicine research at Mayo Clinic. Specific topics: Activities that benefit from increased strength and performance Lifestyle strategies used to enhance strength and performance Common nutritional supplements used to increase strength and performance Safety concerns regarding the use of nutritional supplements Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 9, 2021
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Recommendation for Your Arthritic Patients – Keep Them Moving

Guest: Edward R. Laskowski, M.D. (@DrEdSportsMed)  Host: Darryl S. Chutka, M.D. (@ChutkaMD) Arthritis is one of the most common health conditions our patients have for eliminating exercise from their daily routine, yet the American College of Rheumatology feels that exercise should be one of the mainstays of treatment for those with arthritis. How do we convince our patients of the importance of continued exercise despite their arthritis? Are some types of exercise better than others? Can exercise make their arthritis worse? We’ll discuss these questions with Dr. Edward R. Laskowski, a Sports Medicine physician from the Department of Physical Medicine and Rehabilitation at Mayo Clinic. Specific topics: Benefits of exercise in patients who have arthritis Exercises that patients with arthritis should avoid What patients should do if they have increased joint pain after exercising Joint-friendly exercises that can be done by most patients Importance of performing resistance as well as aerobic exercise Recommended frequency and duration of exercise Exercises for the was with inflammatory arthritis Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 7, 2021
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Nutritional Supplement Edition: Exercise Endurance and Recovery

Guest: Andrew R. Jagim, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Can nutritional supplements help to increase exercise endurance? What types of supplements can help with short term – immediate improvements and which can assist with longer term recovery? Andrew R. Jagim, Ph.D., director of Sports Medicine research at Mayo Clinic joins us to discuss some of the claims that we can hear about nutritional supplements promoted to prove one's endurance, increase exercise economy, and improve tolerance of high-intensity exercise. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 2, 2021
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Mayo Clinic Q&A: Boosters reduce vulnerability to COVID-19 variants

This episode is shared from Mayo Clinic Q&A and was recorded in November, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Omicron, a new COVID-19 variant of concern, has been detected in all regions of the world, including North America. While research and clinical observations on the new strain are underway, it is not yet known what impact, if any, omicron will have on the immune response, transmissibility, or specific COVID-19 treatments. The emergence of omicron is a reminder to take important steps to protect yourself against COVID-19. "The answer is masking and boosters," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.  Dr. Poland is encouraged by vaccine booster rates in the U.S. "In a relatively short period of time, about 36% of adults who are eligible have indeed gotten a booster," says Dr. Poland. "There's plenty of vaccine available. So in the strongest possible terms, I would recommend getting that booster." Adults who are six months past completing their initial Moderna or Pfizer COVID-19 vaccination series are eligible to receive a booster dose, as are adults who are two months past completing their initial dose of the Johnson & Johnson vaccine. On the Mayo Clinic Q&A podcast, Dr. Poland discusses the omicron variant and COVID-19 boosters, and he answers some listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
December 1, 2021
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Nutritional Supplement Edition: A Critical Overview

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, PhD Host: Darryl S. Chutka, M.D. (@ChutkaMD) Imagine taking a supplement that increases muscle mass, improves strength and endurance, promotes weight loss, helps prevent injury from exercise and promotes healing. Do these supplements exist and are they safe? This episode discusses nutritional supplements. We will discuss proven benefits as well as risks. Our guest for this podcast is Andrew R. Jagim, Ph.D., the director of Sports Medicine research at Mayo Clinic. Specific topics: Definition of nutritional supplements Common reasons to take these products Accuracy of claims that nutritional supplements improve fitness and enhance performance Research conducted on nutritional supplements Regulation of the nutritional supplement industry Potential safety issues in taking nutritional supplements Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 30, 2021
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Racism in Pain Medicine

Guest: Natalie H. Strand, M.D. (@DrNatStrand) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Racial biases can influence diagnosis and treatment decisions. It is important to normalize implicit biases and be aware of our own biases to reduce disparities and improve health care for patients. Joining us today is Natalie Strand, M.D., a consultant in the Department of Anesthesiology and Perioperative Medicine at the Mayo Clinic Hospital in Phoenix, AZ. She will discuss the unique, relevant and timely topic of racism in pain medicine, including the occurrence of racism in medicine at all levels – from patient care, diagnoses and outcomes to professional development of physicians. She describes our responsibility and how, if we want to engage in anti-racism, we must do it at all levels in medicine. Additional Resources: Strand, N. H., Mariano, E. R., Goree, J. H., Narouze, S., Doshi, T. L., Freeman, J.A., Pearson, A. C. S. (2021). Racism in Pain Medicine: We Can and Should Do More. Mayo Clinic Proceedings, 96(6), 1394-1400. https://doi.org/10.1016/j.mayocp.2021.02.030 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 23, 2021
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Mayo Clinic Q&A: Travel trends and colder temperatures could mean a COVID-19 holiday surge

This episode is shared from Mayo Clinic Q&A and was recorded in November, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Cold weather, increased travel, waning immunity and the potential for new variants may serve up the perfect recipe for a holiday COVID-19 surge, according to Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.   "I have consistently said what's very likely to happen as we get to the cooler weather and see the trends in travel is that we will have another surge," says Dr. Poland. "We're in this unusual situation where the pandemic is actually getting worse because humans don't want to believe that the pandemic is just as important now as it was a year ago." In this Mayo Clinic Q&A podcast, Dr. Poland answers several listener questions and talks more about being vigilant against COVID-19 as the U.S. heads into a second winter with this coronavirus. He also addresses the recent news that wild deer have shown evidence of COVID-19 infection and what that might mean in the battle to eliminate the disease.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 22, 2021
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Genes and Your Health Series: Hot Topics in Phage Therapy

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Gina A. Suh, M.D. Host: Denise M. Dupras, M.D., Ph.D. What is Phage Therapy? When was it discovered? Where is it used? We know about antibiotics, antifungals, and antivirals, but this is a whole new world! Have no fear, this episode is here from the Genes & Your Health miniseries to help demystify all there is to know about Phages. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
November 18, 2021
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Hyperlipidemia

Guest: Monique A. Freund, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Hyperlipidemia is one of the major risk factors for cardiovascular disease. It’s known that a combination of lifestyle changes and pharmacologic therapy has proven effective in reducing the complications of cardiovascular disease. Despite this, it’s estimated that less than 35% of those patients with hyperlipidemia are adequately managed. Why aren’t we doing a better job at managing this major public health problem? In this podcast, we’ll be speaking with Monique A. Freund, M.D., a cardiologist at Mayo Clinic. We’ll discuss how to optimize management of hyperlipidemia, which lifestyle changes are beneficial, when to use pharmacologic therapy and how to manage patients with statin intolerance. Specific topics: Relative importance of elevated LDLc, low HDLc and elevated triglycerides Effective non-pharmacologic therapy for treating elevated LDLc, low HDLc and elevated triglycerides When to consider starting a patient on a statin Benefits of fish oil Mechanism of action of statins Statin intolerance When to use ezetimibe When to use one of the PCSK9-inhibitors Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 16, 2021
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Genes and Your Health Series: Predicting the Future: What Role is Artificial Intelligence Playing Today and What Can We Expect in the Future?

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Christopher (Chris) A. Aakre (@ChrisAakreMD), M.D.; Bradley J. Erickson, M.D., Ph.D. Host: Denise M. Dupras, M.D., Ph.D. Artificial Intelligence has begun being utilized in Radiology. In fact, it was boldly predicted that Radiology would become an obsolete profession as a result! How has it altered this practice? How will it alter our practices moving forward? Join this episode of our Genes & Your Health miniseries from the Center of Individualized Medicine to learn these answers and more! Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 11, 2021
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The Eyes Have It: Common External Eye Conditions

Guest: Amir R. Khan, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) External eye disorders are commonly seen in a primary care provider’s office, yet very few of us have ever had any formal training in ophthalmology. Fortunately, most of the external eye problems are relatively benign, though not all. It’s important to be able to recognize these conditions since some may be associated with a variety of systemic diseases. In this podcast, Amir Khan, M.D., an ophthalmologist at Mayo Clinic, joins Dr. Chutka to discuss how to recognize commonly seen external eye conditions. Links to specific topics below include additional information and images for most of the covered conditions. Specific topics: Viral versus bacterial conjunctivitis: https://www.mayoclinic.org/diseases-conditions/pink-eye/symptoms-causes/syc-20376355 Scleritis and episcleritis Blepharitis: https://www.mayoclinic.org/diseases-conditions/blepharitis/symptoms-causes/syc-20370141 Sty (Hordeolum): https://www.mayoclinic.org/diseases-conditions/sty/symptoms-causes/syc-20378017 Ectropion versus entropion: https://www.mayoclinic.org/diseases-conditions/ectropion/symptoms-causes/syc-20351164; https://www.mayoclinic.org/diseases-conditions/entropion/symptoms-causes/syc-20351125 Subconjunctival hemorrhage: https://www.mayoclinic.org/diseases-conditions/subconjunctival-hemorrhage/symptoms-causes/syc-20353826 Herpes zoster ophthalmicus Corneal abrasions: https://www.mayoclinic.org/first-aid/first-aid-corneal-abrasion/basics/art-20056659 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 9, 2021
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Mayo Clinic Q&A: Building a wall of immunity against COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in November  3, 2021 Guest:  Elie F. Berbari, M.D. Host: Halena M. Gazelka, M.D. (@hmgazelkamd) In anticipation of more COVID-19 vaccine approvals this week, Dr. Elie Berbari, chair of the Division of Infectious Diseases at Mayo Clinic, says it's good news that younger children will now have more protection against COVID-19. "It's important that we reach a very high level of vaccination rates to achieve kind of a wall of immunity that could prevent transmission and prevent us from these repeated peaks that we've been dealing with over the last year and a half during this pandemic," says Dr. Berbari.  In this Mayo Clinic Q&A podcast, Dr. Berbari also talks about the rare cases of myocarditis and how the Food and Drug Administration is monitoring those cases. Dr. Berbari also addresses additional COVID-19 vaccine doses for immunocompromised people, the importance of masking, even if vaccinated, and he answers a number of listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 5, 2021
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Genes & Your Health Edition – Preparing Your Practice for the Increased Use of Genomics

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Megan A. Allyse, Ph.D. (@MAllyse); Jennifer (Jenny) L. Anderson, M.S., CGC; Radhika Dhamija, M.B.B.S. (@NeurogenesDr) Host: Denise M. Dupras, M.D., Ph.D. Genetic testing is increasingly becoming mainstream. Not only is it first-line testing for many different indications, but we have begun seeing an increase in predictive genomics for healthy patients as well. How can your practice prepare for what is here and what is to come? Tune in to this episode of the Genes & Your Health miniseries from the Center for Individualized Medicine to find out. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 4, 2021
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Developing Equitable Care Models for Diabetic Patients

Guest: Rozalina G. McCoy, M.D., M.S. (@RozalinaMD) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Diabetic research starts with understanding contemporary treatment practices (overtreatment and undertreatment, misuse or underuse of glucose-lowering medications, comparative effectiveness of different diabetes medications), the resulting impact on patient health and the disparities in both treatment practices and outcomes. In this episode Rozalina McCoy, M.D., M.S., associate professor of medicine and consultant in the Division of Community Internal Medicine at Mayo Clinic’s Rochester campus, joins us to discuss developing care delivery models that support high-quality, evidence-based, patient-centered, and equitable diabetes care. Additional resources: McCoy RG, Galindo RJ, Swarna KS, et al. Sociodemographic, clinical, and treatment-related factors associated with hyperglycemic crises among adults with type 1 or type 2 diabetes in the US from 2014 to 2020. JAMA Netw Open. 2021;4(9):e2123471. doi:1001/jamanetworkopen.2021.23471 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 2, 2021
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Genes & Your Health Edition – Genomics for Cardiovascular Health in Primary Care

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guest: Iftikhar J. Kullo, M.D. (@iftikhar_kullo) Host: Denise M. Dupras, M.D., Ph.D. What is familial hypercholesterolemia? Who should be tested for it? Are there genetic variants that are associated with cardiovascular diseases? How young do we start screening? This installment of the Genes & Your Health miniseries from the Center for Individualized Medicine is here to help answer these questions and more! Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 28, 2021
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Preserving Sight with Macular Degeneration

Guest: Sophie J. Bakri, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Macular degeneration is the most common cause of vision loss in individuals over the age of 50. The loss of central vision from macular degeneration can result in significant lifestyle changes in patients. They may no longer be able to read, write or drive. In this podcast, we’ll discuss macular degeneration with Sophie Bakri, M.D., an ophthalmologist at Mayo Clinic. She’ll review the two types and pathology of macular degeneration, its presentation, risk factors and preventive strategies, and new treatments on the horizon. Specific topics: Pathologic changes in macular degeneration Vision loss associated with macular degeneration Possible causes of macular degeneration Risk factors Typical course of macular degeneration The difference between wet and dry macular degeneration Treatment strategies Preventive strategies Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 26, 2021
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Mayo Clinic Q&A: Changing COVID-19 recommendations means the science is working

This episode is shared from Mayo Clinic Q&A and was recorded in October, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) As continuing research guides medical recommendations, it seems that there are COVID-19 updates released daily. These recommendations cover a range of topics, including whether COVID-19 booster vaccinations are necessary to whether COVID-19 vaccines can be mixed and matched. "The fact that recommendations are changing is not evidence people don't know what they're doing," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "It's evidence that they do know what they're doing and are paying close attention to new data that's coming along. Then they're adjusting recommendations based on the latest data." Dr. Poland continues to urge people to get the latest COVID-19 news from credible sources.  In this Mayo Clinic Q&A podcast, Dr. Poland walks through the recent recommendations, corrects misperceptions and answers a number of listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 22, 2021
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Genes & Your Health Edition – Cell-Free DNA: Implications in Practice

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Minetta C. Liu, M.D.; Myra J. Wick, M.D., Ph.D. (@MyraWickMD) Host: Denise M. Dupras, M.D., Ph.D. What is cell-free DNA? How does this type of DNA interact with our body? How is it useful in the clinical setting? Advances in technologies has expanded our understanding of cell-free DNA and its implications. Where are we now and what can we look for in the future? Find out these answers and more in the seventh episode of the Genes & Your Health miniseries from the Center for Individualized Medicine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 21, 2021
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A Neurologist’s Take on Syncope

Guest: Paola Sandroni, M.D., Ph.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Syncope is defined as the sudden and transient loss of consciousness and postural tone due to global reduction of blood flow to the reticular activating system. Syncopal episodes are followed by a rapid and spontaneous recovery.  Joining us today is Paola Sandroni, M.D., Ph.D., a neurologist at Mayo Clinic’s Rochester Campus. She will help us sort through the complicated subject of syncope, including its main etiologies and how to distinguish which is affecting your patient. She also outlines the nuances of evidence-based evaluation of syncope, which is largely guided by the patient’s presentation. Additional resources: Thiruganasambandamoorthy V, Kwong K, Wells GA, Sivilotti MLA, Mukarram M, Rowe BH, Lang E, Perry JJ, Sheldon R, Stiell IG, Taljaard M. Development of the Canadian Syncope Risk Score to predict serious adverse events after emergency department assessment of syncope. CMAJ. 2016 Sep 6;188(12):E289-E298. doi: 1503/cmaj.151469. Epub 2016 Jul 4. PMID: 27378464; PMCID: PMC5008955 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 19, 2021
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Genes & Your Health Edition – Why Does It Matter? Genes, Hormones, and Women’s Health

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Stephanie S. Faubion, M.D., M.B.A. (@StephFaubionMD); Kejal Kantarci, M.D. (@KejalKantarciMD); Juliana (Jewel) M. Kling, M.D., M.P.H. (@DrJewelKling)Host: Denise M. Dupras, M.D., Ph.D. Is hormone therapy good or bad for women? What are the myths surrounding it? Is the varying experience of menopause genetic? Join the sixth episode of Mayo Clinic Center for Individualized Medicine’s Genes & Your Health Edition to dive into women’s health and hormones and what you need to know for your practice.   Additional resources:• USPSTF Recommendations Statement for Breast Cancer: Medication Use to Reduce Risk https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction • Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 14, 2021
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Using Artificial Intelligence to Combat COVID-19

Guest: Thomas Caulfield, Ph.D. Host: Amit K Ghosh, M.D., MBA (@AmitGhosh006) In this podcast, Dr. Thomas Caulfield from Mayo Clinic Florida describes a novel approach for SARS-CoV2 multi-drug targeting using artificial intelligence. Dr. Caulfield is leading a national team of investigators from Harvard, University of California, In Vivo Biosystems and Mayo Clinic to perform large-scale in silico and in vivo experiments on de novo drugs to better understand COVID-19 and halt its progression.  University of California hosts a live virus BSL3 facility for rapidly screening novel compounds that Dr. Caulfield's lab designs in silico and refines with feedback using machine learning techniques and data layering. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 12, 2021
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Genes & Your Health Edition – How Does Your Microbiome Impact Your Health?

To claim credit for this series, visit: Mayo Clinic Talks Podcast: Genes & Your HealthGuest: Purna C. Kashyap, M.B.B.S. (@KashyapPurna); Marina R. Walther-Antonio, Ph.D.Host: Denise M. Dupras, M.D., Ph.D. What is the microbiome? How does the microbiome interact with our body? How much of us is nurture, how much is nature? The whole concept of microbiome may be a new idea but have no fear this fifth episode of the Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine is here to help answer those questions and more! Additional resources: Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 7, 2021
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Mayo Clinic Q&A: Breaking Down COVID-19 Vaccine Booster Approvals

This episode is shared from Mayo Clinic Q&A and was recorded in September 29, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The path to approvals for a booster dose of the Pfizer COVID-19 vaccine has seemed complicated.  "This is a confusing set of recommendations," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "So let's look at the four groups approved for only the Pfizer booster, thus far. If you got a primary series of the Pfizer vaccine, you're 65 and older, and it's been six months or more, you are eligible for a booster. If you're 50–64 and you have medical conditions that place you at high risk, you are eligible for the booster. If you're 18–49, you may be able to get a booster based on a medical condition and if you talk with your health care provider to weigh risks and benefits. And, finally, for people 18–64 years old, who are health care providers in congregate living situations or who have occupations that place them at high risk for transmission, such as school teachers, they also may be eligible. That should happen very soon." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about the approval process for COVID-19 vaccine boosters, including for the Moderna and Johnson & Johnson COVID-19 vaccines. He also discusses the possibility that emergency use approval for children, down to age 5, could come before the end of October. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 6, 2021
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Breast Imaging for Patients with Dense Breast Tissue

Guest: Christina A. Dilaveri, M.D. (@CDilaveri) Host: Darryl S. Chutka, M.D. (@ChutkaMD)   Breast cancer is very treatable when detected early. Therefore, early detection becomes very important as it significantly reduces a patient’s risk of developing metastases and death. Breast imaging plays an extremely important role in the detection of early breast cancer, and we now have several modalities of breast imaging available, each with its advantages and disadvantages. Our guest for this podcast is Christina Dilaveri, M.D. a breast disease specialist, from Mayo Clinic’s Rochester Campus. We’ll discuss mammography, ultrasound, MRI, and molecular breast imaging, when they’re indicated, and the advantages of each. You’ll hear which patients should have more than a mammogram and how often it should be performed. Specific topics discussed: The various types of mammography available Indications for breast ultrasound Benefits of breast MRI When breast MRI should be performed Benefits of molecular breast imaging When molecular breast imaging should be performed Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 5, 2021
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Genes & Your Health Edition – Genomics and Cancer: Primary Care Impact and Research Advances

To claim credit for this series, visit: Mayo Clinic Talks Podcast: Genes & Your Health   Guest: Niloy Jewel J. Samadder, M.D. (@J_Samadder)  Host: Denise M. Dupras, M.D., Ph.D.   Can we find the cause of a patient’s cancer? Is it possible to provide targeted treatment to prevent future cancers by understanding what genetic predispositions a patient or their family members have? In a recently published study, nearly one in six to one in eight cancer patients, depending on which type of cancer they had, carried a genetic predisposition to the development of their cancer. How can we translate these findings into our practice for the benefit of our patients and their families? Tune in to episode four of our Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine. Additional resources: Samadder NJ, Riegert-Johnson D, Boardman L, et al. Comparison of universal genetic testing vs guideline-directed targeted testing for patients with hereditary cancer syndrome. JAMA Oncol. 2021;7(2):230–237. doi: 10.1001/jamaoncol.2020.6252 Uson, PLS. Riegert-Johnson, D. Boardman, L. Kisiel, J. et al. Germline cancer susceptibility gene testing in unselected patients with colorectal adenocarcinoma: a multicenter prospective study. Clin Gastroenterol Hepatol. 2021 April 20; doi: 10.1016/j.cgh.2021.04.013 Mayo Clinic’s Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 30, 2021
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The Evolution of COVID-19 Testing

Guest: Matthew J. Binnicker, Ph.D. (@DrMattBinnicker) Host: Amit K. Ghosh, M.D. (@AmitGhosh006)   In this podcast Matthew J. Binnicker, Ph.D. discusses the development of different types of testing available to diagnose SARS-CoV2 infection. Binnicker discusses the test characteristics of the rapid antigen tests and RT-PCR test and its variability based on the time when the test was performed. He also discusses the optimal timing of diagnostic testing (rapid testing, RT-PCR) and the role and limitations of antibody testing in COVID-19.   Additional resources: Shah AS, Tande AJ, Challener DW, O’Horo JC, Binnicker MJ, Berbari EF. Diagnostic stewardship: An essential element in a rapidly evolving COVID-19 pandemic. Mayo Clin Proc. 2020;95(9):S17-S19. DOI: https://doi.org/10.1016/j.mayocp.2020.05.039   Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 28, 2021
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Genes & Your Health Edition – Pharmacogenomics and its Value for Primary Care

To claim credit for this episode, visit: https://ce.mayo.edu/online-education/content/mayo-clinic-talks-podcast-genes-your-health#group-tabs-node-course-default1 Guest: Jessica A. Wright, Pharm.D., R.Ph. Host: Denise M. Dupras, M.D., Ph.D. Pharmacogenomics helps to identify how your patients’ DNA may affect their response to medications. But there's a lot of different genes! How do we get started? What resources are out there? Do we have to worry about every drug a patient is on? Find out these answers and more in episode three of the Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine. Additional resources: PharmGKB: pharmgkb.org Clinical Pharmacogenetics Implementation Consortium (CPIC®): cpicpgx.org Basic Pharmacogenomics Nomenclature: https://www.pharmgkb.org/page/glossary NIH’s National Human Genome Research Institute: Healthcare Provider Resources: https://www.genome.gov/For-Health-Professionals/Provider-Genomics-Education-Resources Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 23, 2021
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Regenerative Techniques for the Larynx

Guest: David G. Lott, M.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) About 60,000 Americans have had their vocal cords removed due to disease or trauma necessitating a laryngectomy. Post-laryngectomy, patients are unable to speak, are at risk for aspiration, and many suffer from significant anguish resulting in depression. Fortunately, there are several treatment options available, the first being laryngeal transplant. While laryngeal transplantation allows patients to smell, taste, swallow, and communicate, it has drawbacks. Currently only a small number of larynx transplants are done in the U.S., and only a select few patients with laryngectomy qualify for larynx transplant. In this episode, Dr. David Lott, division chair of laryngology at Mayo Clinic’s Arizona campus, discusses the role of regenerative medicine, which has shown promise in using 3D printing and a patient’s stem cells in creating a larynx. Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 21, 2021
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Genes & Your Health Edition – How Does Viral Genetics Influence Transmission, Diagnosis, and Severity of COVID-19?

To claim credit for this series, visit: https://ce.mayo.edu/online-education/content/mayo-clinic-talks-podcast-genes-your-health#group-tabs-node-course-default1 Guests: Andrew D. Badley, M.D. (@BadleyAndrew); Matthew J. Binnicker, Ph.D. (@DrMattBinnicker) Host: Denise M. Dupras, M.D., Ph.D. COVID-19. Variants. The future. Does one test fit all?  Will the vaccine continue to provide protection against future variants? What makes the Delta variant more transmissible? Join the second episode of our Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine to learn how viral genetics influence transmission, diagnosis, and severity of COVID-19. Additional resources: Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 16, 2021
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Genes & Your Health Edition – Genomics and Healthcare, Why Does it Matter?

To claim credit for this episode, visit: https://ce.mayo.edu/online-education/content/mayo-clinic-talks-podcast-genes-your-health#group-tabs-node-course-default1 Guests: Matthew J. Ferber, Ph.D. (@Matt_Ferber); Teresa M. Kruisselbrink, M.S., CGC (@T_Kruisselbrink); William C. Palmer, M.D. (@williampalmermd) Host: Denise M. Dupras, M.D., Ph.D. For so long we've heard Genetic Testing is coming. Well guess what, it’s here!  We have over 25 million people who have chosen to participate in direct-to-consumer testing alone. What does this mean for primary care, and does it matter? Find out in the first episode of our Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine. Additional resources: TAPESTRY Study: https://www.mayo.edu/research/clinical-trials/cls-20477323?_ga=2.268706548.460922620.1627479724-1519128218.1623079535 Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 14, 2021
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Variants, Virulence, and Vaccines, Oh My!

Guest: Elitza S. Theel, Ph.D. (@ElliTheelPhD) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Dr. Elitza Theel, Professor of Laboratory Medicine and Pathology and Director of Infectious Diseases Serology Laboratory at Mayo Clinic’s Rochester Campus, discusses our immune response to vaccination and natural infection and outlines the different types of antibody assays currently available. Dr. Theel also discusses the concept of herd immunity in the context of different circulating SARS-CoV-2 variants and the increased need to get higher rates of vaccination in the community as the infectivity and transmissibility of circulating SARS-CoV-2 variants changes. We also discuss the status of correlates of protective immunity against SARS-CoV-2 and the need for booster vaccine doses for immunocompromised individuals.  Additional resources: Interim Guidelines for COVID-19 Antibody Testing in Clinical and Public Health Settings https://www.cdc.gov/coronavirus/2019-ncov/lab/resources/antibody-tests-guidelines.html Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 7, 2021
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Evaluating Hematuria

Guest: Aaron M. Potretzke, M.D. (@potretzke) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Microscopic hematuria, and less commonly gross hematuria, are conditions commonly seen by the primary care provider. Malignancy is the most ominous cause of hematuria. Fortunately, other causes are much more likely. Since this is a relatively common health condition, when should we investigate hematuria and what should the evaluation consist of? How do we evaluate a patient’s risk for urinary tract malignancy? Dr. Aaron Potretzke, a urologist at Mayo Clinic joins us to discuss these questions. Specific topics: Definition of hematuria Benign causes of hematuria Risk of malignancy in low, medium, and high-risk patients Stratifying malignancy risk in patients for genitourinary malignancy Recommended evaluation for patients with hematuria How to manage patients with persistent hematuria despite a negative evaluation Role of urine cytology in the evaluation of hematuria Additional resources: American Urological Association hematuria guideline and algorithm: https://www.auanet.org/guidelines/guidelines/microhematuria Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 31, 2021
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Exercise is First-Line Treatment for Your Parkinson’s Patients

Guest: Edward R. Laskowski, M.D. (@DrEdSportsMed) Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) Daily exercise has so many health and emotional benefits – it can help decrease your blood pressure, promote cardiovascular wellbeing, alleviate stress, and assist with weight loss and blood sugar control. Parkinson’s disease is a condition that affects the central nervous system, and in particular the brain, that can lead to shakiness, poor balance, and frequent falls. Joining us in this episode is Edward Laskowski, M.D., a professor of physical medicine and rehabilitation and sports medicine specialist at Mayo Clinic’s Rochester Campus, to discuss why exercise is first-line treatment for your Parkinson’s patients. Additional resources: Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055 The Michael J. Fox Foundation for Parkinson’s Research: https://www.michaeljfox.org/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 24, 2021
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Parkinson’s Disease – It’s More Than Just a Tremor

Guest: Jeremy K. Cutsforth-Gregory, M.D. (@JCGneuro) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Parkinson’s Disease is one of the more common neurodegenerative diseases, in fact, patients with Parkinson’s outnumber those with multiple sclerosis, ALS, and muscular dystrophy combined. It tends to affect older patients, although on rare occasions it can be seen in those under the age of 50. It can have a devastating effect on an individual’s lifestyle as the physical symptoms of the disease tend to gradually progress over years. This podcast will feature Dr. Jeremy Cutsforth-Gregory, a neurologist at the Mayo Clinic, as we discuss the evaluation and management of Parkinson’s Disease. Specific topics: Pathophysiology of Parkinson’s Disease Common presenting symptoms of Parkinson’s Assessing patients with tremor Complications of advanced Parkinson’s Pharmacologic management of Parkinson’s Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 17, 2021
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Working from the Ground Up to Impact Gender Disparities in COVID-19

Guest: Carol L. Kuhle, D.O., M.P.H. (@clkejd) Host: Anjali Bhagra, M.D. (@anjalibhagramd) Anjali Bhagra, M.D., and Carol L. Kuhle, D.O., M.P.H., discuss the narrative they recently published in Mayo Clinic Proceedings, which outlines and highlights the further widening of preexisting gender disparities in response to the COVID-19 pandemic. What can we do to identify and mitigate these issues? Additional resources: Nordhues, HC. Bhagra, A. Stroud, NN. Vencill, JA. Kuhle, CL. COVID-19 gender disparities and mitigation recommendations: a narrative review. Mayo Clin Proc. 2021 April 20; 96(7): 1907-1920. doi: https://doi.org/10.1016/j.mayocp.2021.04.009 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 10, 2021
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Mayo Clinic Q&A: The COVID-19 Delta Variant has Changed Everything

This episode is shared from Mayo Clinic Q&A and was recorded August, 2021 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd)   A fourth COVID-19 surge is blanketing the U.S., and the delta variant is the culprit. "Where did this delta variant come from? It came from unvaccinated people getting infected in large numbers allowing the virus to continue mutating," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. In the past, a person with COVID-19 might infect two to four people. But with the delta variant, one person can infect nine people, according to Dr. Poland. He says if you want to protect yourself and your family, wear a mask, especially indoors, and get vaccinated with an appropriate series of one of the COVID-19 vaccines. "These are the most studied vaccines in the history of the world," Dr. Poland emphasizes. "There have never been this many people who have received this many doses of vaccines during this amount of time with as much scrutiny as these COVID-19 vaccines have had." In this Mayo Clinic Q&A podcast, Dr. Poland answers questions about a person's waning immunity and the likelihood of COVID-19 booster shots. He also explains the two phases of immunity and goes into detail about the extensive Federal Drug Administration license approval process for COVID-19 vaccines. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 6, 2021
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Will We Be Replaced by Computers? Artificial Intelligence and Medicine

Guest: Steve G. Peters, M.D. Host: Sanjeev Kakar, M.D. (@sanjkakar) No doubt you’ve heard the term “artificial intelligence,” by now; but what is it exactly? How can medicine use AI to improve patient care and outcomes? Will it one day replace doctors’ years of training? Steve Peters, M.D. a pulmonary and critical care medicine consultant, with a special interest in AI, at Mayo Clinic’s Rochester campus. Dr. Peters will help us take a look into the not-so-distant future as we explore AI and its role in medicine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 3, 2021
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Mayo Clinic Q&A: Stopping the Spiral of the COVID-19 Delta Variant

This episode is shared from Mayo Clinic Q&A and was recorded July, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    Transmission of the COVID-19 delta variant is increasing. "We're in this constant spiral, right now,” says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. “The delta variant is so highly contagious,” he says. “The number of delta viral particles in the upper respiratory system is reportedly 1,000 times higher than with the original COVID-19 virus. If we can't find ways to get people vaccinated, we are going to be in a world of hurt. And I don't say that to be alarmist. I say it to be a realist, based on what’s happening right in front of us.” But Dr. Poland says the spiral can be stopped by getting higher rates of immunization.  "Getting a COVID-19 vaccine will prevent the development of worse and worse variants. It will prevent severe cases of hospitalization and death, even in the face of a variant,” he says. "The alternative is to lose another 600,000-plus Americans. Only this time it will, unfortunately, involve younger people." Dr. Poland explains further, "Every time somebody gets infected with the delta variant, there's the opportunity for that virus to mutate and transmit to other people," says Dr. Poland. "This means that immunization rates to control herd immunity will probably have to be in the 85% to 95% range." In this Mayo Clinic Q&A podcast, Dr. Poland continues to talk about the delta variant, breakthrough infections, booster shots and much more. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 30, 2021
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What’s That Sound? Maybe It’s Stridor

Guest: Shelagh A. Cofer, M.D. (@ShelaghCoferMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Stridor is a musical sound due to disrupted airflow in an individual’s airway. In many instances it’s due to a benign cause but it can also represent a serious problem, possibly even life-threatening. In today’s podcast, we’ll learn about the various causes of stridor and when we need to be concerned that it represents a serious health issue. Our guest for this podcast is Dr. Shelagh Cofer, a pediatric otolaryngology specialist at the Mayo Clinic. We’ll discuss how stridor differs from wheezing, the most common causes of stridor in both children and adults and what symptoms we should be watching for that might suggest a serious cause for stridor. We’ll also cover the evaluation of patients with stridor, which imaging studies may be helpful and when an ENT consultation is warranted. Specific topics: Definition of stridor Difference between stridor, stertor, and wheezing Most common causes of stridor in both children and adults Croup as a form of stridor Important questions we should be asking our patients about stridor to identify those at risk for airway obstruction – including the SPECS-R mnemonic Tests and imaging studies which may be helpful in the evaluation of a patient with stridor Treatments for the more common causes of stridor Additional resources: Zoumalan, R; Maddalozzo, J; Holinger, LD. Etiology of stridor in infants. Ann Otol Rhinol Laryngol. 2007; 116(5):329-334. doi: 10.1.1896.429 https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.896.429&rep=rep1&type=pdf Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 27, 2021
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Mayo Clinic Q&A: On the Verge of Predicted COVID-19 Surge with Delta Variant

This episode is shared from Mayo Clinic Q&A and was recorded July, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    The delta variant is being blamed for hot spots in the U.S. where cases of COVID-19 are on the rise. These hot spots account for most cases in the U.S. They are also the geographical areas that tend to have the lowest vaccination rates.  "It's no surprise that the two go together," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "This (delta variant) is the bad actor that we predicted it would be," adds Dr. Poland. "Our seven-day average is getting up to 19,000 cases a day in the U.S. We were down to 3,000. So we're starting to see, just as we predicted, a surge as people took masks off and as restrictions were lifted before we had achieved high rates of immunization." In this Mayo Clinic Q&A podcast, Dr. Poland expands on how the highly transmissible delta variant continues to spread. He also talks about the possibility of COVID-19 vaccine boosters, explains how the Vaccine Adverse Event Reporting System works, and much more as he answers listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 22, 2021
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Multidisciplinary Approach to Pelvic Pain

Guest: Isabel C. Green, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Pelvic pain can be challenging. It can have a variety of presenting symptoms since it can originate from a variety of organ systems. When pelvic pain becomes chronic, it becomes even more challenging. It’s associated with significant direct medical costs as well as indirect costs as it frequently results in work absenteeism. Patients with chronic pelvic pain are often initially evaluated by primary care providers, but referral to specialists is quite common. Due to the variety of symptoms associated with chronic pelvic pain, multiple specialties often are asked to evaluate these patients. This frequently results in patients being passed back and forth between various medical specialties. It therefore becomes important for primary care providers to become comfortable evaluating and managing patients with pelvic pain. Our guest for this podcast is Dr. Isabel Green, a physician from the Department of Obstetrics and Gynecology at the Mayo Clinic. We’ll discuss how to effectively evaluate patients with pelvic pain, “red flag symptoms” to watch for, useful laboratory tests to order, and common imaging studies which can be helpful in establishing a cause for the pain. We’ll also discuss the benefits of a multi-disciplinary approach to pelvic pain. Specific topics: Categorization of pelvic pain Appropriate evaluation of pelvic pain including the clinical history, physical exam, laboratory tests and imaging studies Relationship of chronic pelvic pain with other symptoms such as anxiety, depression, insomnia, and work/relationship issues Chronic pelvic pain representing a form of centralized pain Advantages of a multi-disciplinary approach to evaluating and managing chronic pelvic pain Additional resources: Chronic pelvic pain: ACOG practice bulletin, number 218. Obstet Gynecol. 2020 Mar; 135(3):e98-e109. doi: 1097/AOG.0000000000003716. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 20, 2021
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Identifying and Treating Urinary Urge Incontinence

Guest: Brian J. Linder, M.D. (@brianjlinder) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Patients rarely mention urinary incontinence to us as a problem as many assume it’s a normal change of aging. However, it’s a major quality-of-life issue. Many with incontinence are reluctant to go out in public and those who do, usually know the location of all the nearby restrooms. Yet, with proper evaluation and treatment, essentially all patients can be helped, and in many cases, they can be cured. In this podcast, we’ll discuss urgency urinary incontinence, one of the most common forms of incontinence. We’ll cover the questions you should ask your patients to make a diagnosis, what evaluation you should do, and what treatment options are available. Our guest for this topic is Dr. Brian Linder, a urologist at the Mayo Clinic. Specific topics: The various types of urinary incontinence Important questions to ask patients to make a diagnosis Effective use of a voiding diary Physical exam recommendations Helpful laboratory tests When urodynamic studies are indicated Non-pharmacologic treatment options Medications useful in treating urgency incontinence Treatment options for the refractory patient Additional resource: https://www.auanet.org/guidelines/overactive-bladder-(oab)-guideline Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 13, 2021
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Mayo Clinic Q&A: Summer Travel and People Not in Your Bubble During COVID-19 Pandemic

This episode is shared from Mayo Clinic Q&A and was recorded June, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    "The reason we have the COVID-19 delta variant, the reason we have the delta plus variant is because of unimmunized people who get infected," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. He adds that 99.2% of the recorded COVID-19 deaths in the U.S. are in people not vaccinated against the virus.  This is why he cautions folks who may be traveling this Fourth of July holiday and throughout the summer.  "You don't know what variants people are carrying, how symptomatic they are, the health of their immune system, or if they've been vaccinated," says Dr. Poland. "When you are around groups of people indoors that are not in your bubble, so to speak, I think you should still wear a proper mask."  In this Mayo Clinic Q&A podcast, Dr. Poland explains why, even if you are fully vaccinated for COVID-19, you should still consider being masked in some situations. He also discusses breakthrough infections in certain subpopulations, and what that may mean for needing booster shots. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 7, 2021
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Postural Orthostatic Tachycardia Syndrome (POTS) in Adult Patients

Guest: Jeremy K. Cutsforth-Gregory, M.D. (@JCGneuro) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Postural Orthostatic Tachycardia Syndrome, or POTS, is a medical condition manifested by tachycardia that occurs after standing or prolonged sitting and is often associated with symptoms such as dizziness, fatigue, and occasionally syncope. POTS can be difficult to diagnose as patients often present with a variety of vague, and what seem like unrelated, symptoms. Management of patients with POTS can be equally difficult as there’s no one treatment which is effective in all patients. However, patients with POTS often have typical symptoms and objective findings on physical exam. Once a diagnosis is made, effective treatment is available and many patients with POTS can be helped with non-pharmacologic therapy. To help us understand POTS and its management, we’ll speak with Dr. Jeremy Cutsforth-Gregory, a neurologist at the Mayo Clinic. We’ll discuss the proposed theories regarding the cause of POTS, the different types of POTS, pathologic findings in patients with POTS, and the management of patient with POTS. Specific Topics: Typical symptoms of POTS Risk factors for POTS Theories regarding the cause of POTS Description of the varieties of POTS How to diagnose POTS Pathologic and pharmacologic abnormalities related to POTS Management of patients with POTS Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 6, 2021
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Regenerative Medicine Edition Ep.10: FDA Regulatory Process and Clinical Trials

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Drew M. Witter, CCRP Host: Darryl S. Chutka, M.D. (@ChutkaMD) “Stem Cell Clinics” throughout the U.S. promote stem cell therapy for a variety of health conditions including osteoarthritis, autism, macular degeneration, Parkinson’s Disease, Alzheimer’s Disease and most recently COVID-19 infections. How can our patients be assured that the regenerative medicine therapy effectively treats their health condition and the products they receive are safe? In this podcast, we discuss regulations regarding regenerative medicine, the process of obtaining FDA-approval and which regenerative medicine therapies are FDA-approved. Our guest will be Drew Witter, a Program Manager from the Office of Research and Regulatory Support at the Mayo Clinic. Specific topics discussed: Process of taking regenerative medicine from the research lab to the clinical practice How regulators ensure the safety and effectiveness of regenerative therapies The process of acquiring FDA-approval Regenerative medicine therapies that are FDA-approved How patients and clinicians learn of FDA-regulated regenerative medicine clinical trials Additional resources: Clinical Trials available at Mayo Clinic through the Center for Regenerative Medicine: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-trials U.S. National Library of Medicine: https://www.clinicaltrials.gov/ Center Watch: https://www.centerwatch.com/ Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 1, 2021
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Primary Care Management of the Post-Prostate Cancer Patient

Guest: Matthew K. Tollefson, M.D. (@MattTollefsonMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Other than skin cancer, prostate cancer is the most common cancer in men in the United States and will affect 1 in every 6 men 65 years and older. Fortunately, when detected early, it is very treatable. Long-term follow-up of patients with treated prostate cancer is usually performed by primary care providers. How often should these patients be seen? How much of an exam is recommended? Which tests should be ordered? When are imaging tests indicated and which studies are the most helpful? This podcast will address these questions and more as we discuss the primary care management of the post-prostate cancer patient with Dr. Matthew Tollefson, a urologist from the Mayo Clinic. Specific topics discussed: Current treatment options for prostate cancer Determinants for choosing one of the treatment options for prostate cancer When and how often patients should receive follow-up for prostate cancer Laboratory tests recommended for the follow-up of prostate cancer patients When a detectable PSA is concerning following prostate cancer treatment Imaging studies recommended for following prostate cancer patients and when they are indicated Treatment options for recurrent prostate cancer Future treatment options for prostate cancer which have potential Additional resources: https://www.auanet.org/guidelines/advanced-prostate-cancer https://www.mayoclinic.org/diseases-conditions/prostate-cancer/symptoms-causes/syc-20353087 https://www.mayoclinic.org/medical-professionals/urology Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 29, 2021
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Mayo Clinic Q&A: COVID-19 Vaccination Rates Stalling, Infections From the Delta Variant Rising

This episode is shared from Mayo Clinic Q&A and was recorded June 21, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    Summer and fall are going to be a dangerous time for people in the U.S. who have not been vaccinated for COVID-19, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.  "I really think this exponential rise in the number of sequences that are delta must be taken seriously," says Dr. Poland. "We are seeing a surge again, in hospitalizations in the UK, because of the delta variant in people who have not been vaccinated or who only got one dose of vaccine. This is a really critical message for the public to hear because in the U.S. we are stalled in vaccination rates." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about a possible COVID-19 surge and being emotionally ready for the pandemic to be over. He also answers listener questions about COVID-19 reinfection, the latest on antiviral development for COVID-19, and the latest news about COVID-19 vaccines affecting menstrual cycles and sperm quality. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 25, 2021
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Regenerative Medicine Edition Ep.9: Cardiac Regenerative Therapies

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Atta Behfar, M.D., Ph.D. (@AttaBehfar) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Traditional treatment of cardiac disease, especially advanced congestive heart failure has been limited. Transplantation has potential for benefit; however, organ shortage remains a barrier. It’s anticipated that regenerative medicine will help solve this unmet need with new treatment options to repair damaged heart tissue. This podcast will discuss regenerative medicine for cardiovascular disease with Dr. Atta Behfar, a Mayo Clinic cardiologist with expertise in advanced heart failure and transplantation. We’ll review the progress made in regenerative medicine in management of cardiovascular disease, what treatment options are currently available and the potential treatment options which will become available in the future. Specific topics discussed: Regenerative potential of the cardiovascular system Current challenges in management of patients with cardiovascular disease Progress in regenerative medicine for the cardiovascular system Limitations in regenerative cardiac therapy using regenerative medicine Future potential for regenerative medicine treatment of cardiovascular disease Patients who are candidates for cardiac regenerative therapies  Additional resources: Clinical Trials available at Mayo Clinic through the Center for Regenerative Medicine: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-trials U.S. National Library of Medicine: https://www.clinicaltrials.gov/ Center Watch: https://www.centerwatch.com/  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 24, 2021
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Mayo Clinic Q&A: Examining Reports of Heart Inflammation in Young People After Second COVID-19 Vaccine

This episode is shared from Mayo Clinic Q&A and was recorded June 14, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices is holding an emergency COVID-19 meeting this week to discuss COVID-19 vaccine safety as it relates to news that young people may develop myocarditis after receiving a second dose of a messenger RNA COVID-19 vaccine. Myocarditis, which is an inflammation of the heart muscle, is usually caused by a viral infection. But it can result from a reaction to a drug or be part of a more general inflammatory condition. Signs and symptoms include chest pain, fatigue, shortness of breath and arrhythmias. "There have been about 789 cases reported," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And that can happen for a whole variety of reasons."  In this Mayo Clinic Q&A podcast, Dr. Poland details the concerns about the myocarditis reports. He also discusses the latest news on the COVID-19 delta variant, and he explains what scientists are calling the "two-track pandemic." AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 23, 2021
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The Sobering Statistics of Alcohol Use Disorder

Guest: Terry D. Schneekloth, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) According to the 2019 National Survey on Drug Use and Health, nearly 26% of individuals 18 and older reported that they engaged in binge drinking and slightly over 6% engaged in heavy alcohol use within the past month. Binge drinkers were 70 to 90 times more likely to have an alcohol-related emergency department visit. Based on their data from this study, they estimated that nearly 15 million people ages 12 and older had alcohol use disorder. It’s also known that those with alcohol use disorder commonly seek care from primary care providers for alcohol-related medical problems. Our guest for this podcast is Terry Schneekloth, M.D., a psychiatrist and addiction specialist at Mayo Clinic. Specific topics discussed: Definition of alcohol use disorder Risk factors for alcohol use disorder Role of genetics Questions primary care providers should ask to explore the possibility of an alcohol use disorder in patients Physical exam or lab findings which could suggest an alcohol use disorder Available treatment options and their alcohol use disorder effectiveness Additional Resources: World Health Organization (WHO). Alcohol Use Disorders Identification Test (AUDIT). 2001 November 18; https://www.who.int/publications/i/item/audit-the-alcohol-use-disorders-identification-test-guidelines-for-use-in-primary-health-care National Institute on Alcohol Abuse and Alcoholism (NIAAA). National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study: https://www.niaaa.nih.gov/research/nesarc-iii Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 22, 2021
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Regenerative Medicine Edition Ep.8: Neuroregenerative Therapies

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Nathan Staff, M.D. (@NathanStaffMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The cells in our nervous system are extremely specialized, especially those in the brain. Unfortunately, nervous tissue does not have a great potential to regain function once it is lost. Exciting research is being done in the field of neuro-regenerative medicine which will give hope for improvement to those with chronic neurodegenerative disease or nerve damage from injury. Dr. Nathan Staff, a Mayo Clinic neurologist, joins us regarding the challenges with the current management of chronic neurodegenerative diseases and the future potential for treating such conditions as Parkinson’s Disease, Alzheimer’s Disease, ALS and other neurodegenerative disease with regenerative medicine therapies. Specific topics discussed: Current research in regenerative medicine treatment for chronic neurodegenerative disease Currently used regenerative medicine in neurologic conditions New treatment options on the horizon for chronic neurodegenerative disease using regenerative medicine therapy  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 17, 2021
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The Agony of Da Feet – Assessing Foot and Ankle Pain and Injury

Guest: Daniel B. Ryssman, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Generally, we take our feet for granted. It’s not unusual for a person to take 8- to 10-thousand steps per day. That translates to over 115,000 miles in a lifetime. By the time we reach 70 years old, the average person will have walked the equivalent of 4 times around the globe. Yet, we stop taking our feet for granted when they hurt, and it’s estimated that 75% of Americans will experience foot problems of varying degrees of severity during their lifetime. In this podcast, we’ll discuss foot and ankle pain with Daniel Ryssman, M.D., an orthopedist and sports medicine physician from Mayo Clinic. We’ll review some of the common injuries to the ankle such as sprains and fractures as well as common chronic conditions of the foot such as plantar fasciitis and bunions. Dr. Ryssman delves into the best ways to prevent, diagnose, and treat these conditions as well as what, if any, imaging to order. Specific topics discussed: Ankle sprains Ankle fractures Achilles’ tendon rupture Plantar fasciitis Bunions Metatarsalgia Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 15, 2021
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COVID-19 Miniseries Episode 75: Mayo Clinic Q&A – A Dangerous Phase of the COVID-19 Pandemic for Those who are Unvaccinated

This episode is shared from Mayo Clinic Q&A and was recorded June, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    If you've been vaccinated for COVID-19, you're able to go shopping, eat in restaurants and travel on airplanes without the same worry of becoming infected with COVID-19 that existed just months ago. But for those who are unvaccinated, getting infected with COVID-19 — even with just minor symptoms — should be a concern, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "For those who have been vaccinated, life is resuming back to a sense of normalcy," says Dr. Poland. "But for the unvaccinated, they now live in a dangerous phase of the pandemic, where we're seeing circulating variants that are much more transmissible and may cause worse cases of the disease than what happened last year at this time. I think the people who are unvaccinated may not realize that." In this Mayo Clinic Q&A podcast, Dr. Poland also offers information on more COVID-19 studies underway and he talks about COVID-19 vaccine research protocols that will be able to help scientists with other vaccine research, such as HIV vaccine research. Also, he answers listener questions, such as, "Does someone who has already been infected with COVID-19, really need to be fully vaccinated for COVID-19 or would just a booster be needed?" AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 11, 2021
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Regenerative Medicine Edition Ep.7: Preventing Osteoarthritis of the Knee

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Daniel Saris, M.D., Ph.D. (@sarisnl) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Osteoarthritis of the knee is extremely common, and it’s estimated that 1 in 2 people are likely to develop symptomatic knee osteoarthritis in their lifetime. Its known that damaged cartilage is the precursor to osteoarthritis. Many individuals have had partial or complete meniscectomies for meniscal tears in the past and those individuals were then likely to eventually develop knee osteoarthritis. What if damaged cartilage was repaired instead of surgically removed? Could that be an effective treatment recommendation we could give to our patients to help prevent or treat osteoarthritis? Our podcast guest today is Dr. Daniel Saris and he has some fascinating information related to cartilage damage and repair using regenerative medicine techniques. Specific topics discussed: How meniscal damage relates to osteoarthritis Ability of cartilage to repair itself when damaged Repairing a damaged meniscus instead of a partial or complete meniscectomy Specific techniques of repairing cartilage Success in treating patients with cartilage repair Future treatment options for osteoarthritis using regenerative medicine  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 10, 2021
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COVID-19 Miniseries Episode 74: The World is Flat – Addressing Anosmia in Post-COVID Patients

Guest: Erin K. O'Brien, M.D. (@ErinOBrienMD)  Host: Amit K. Ghosh, M.D. (@AmitGhosh006)  Erin O’Brien, M.D., division chair of Rhinology in Rochester, MN, joins us again to provide an evidence-based update on anosmia and its prevalence in post-COVID patients. She reviews the postulated mechanism by which anosmia occurs in this group of patients, and how this effects patients’ safety, mental health, and overall wellbeing. Dr. O’Brien also gives an overview of treatment options, such as various methods of olfactory training, and what physicians need to know when counseling their patients with post-COVID anosmia.  Additional resources:  Video on olfactory training: https://www.youtube.com/watch?v=Qrr0so6pFOs  Abscent – resources for patients with anosmia: https://abscent.org/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 8, 2021
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Regenerative Medicine Edition Ep.6: New Options for Treating Musculoskeletal Pain

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Shane A. Shapiro, M.D. (@ShaneShapiroMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Musculoskeletal pain is extremely common and when severe, patients often gain significant benefit from joint replacements. However, until our patients reach the point where surgery is an option, our efforts to help patients with the chronic joint pain often leave much to be desired. A relatively new treatment approach has appeared in the past decade, musculoskeletal regenerative medicine. But does the research back up the numerous claims of benefit? This podcast will review the current treatment options available and future potential of regenerative medicine for musculoskeletal problems with Dr. Shane Shapiro, a sports medicine physician in the Department of Orthopedics at the Mayo Clinic. We’ll discuss the current regenerative products and therapies available to optimize patient outcomes, potential adverse effects of the therapies and the numerous claims by many clinicians regarding the benefit potential for regenerative medicine in musculoskeletal disease.  Specific topics discussed: Challenges of currently available traditional treatment for musculoskeletal conditions Benefits of stem cell injections for osteoarthritis Potential adverse effects of stem cell injections Currently available regenerative medicine therapies that have shown benefit to patients Validity of the many claims made by clinicians regarding the benefits of stem cell injections  Additional educational opportunities from Mayo Clinic:  https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 3, 2021
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Watching Out for Loperamide Abuse

Guest: Tyler S. Oesterle, M.D., M.P.H. (@OesterleMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Opioid abuse remains a significant problem, and as law enforcement and regulatory agencies tighten access to prescription analgesics, individuals are seeking alternatives. It’s been discovered that when taken at very high doses, loperamide can produce similar effects to the opioid analgesics and the drug is inexpensive when compared to the price of both illicit and prescription opioids. As a result, loperamide abuse has become a significant problem. In this episode we discuss loperamide abuse with Tyler Oesterle, M.D., M.P.H., a psychiatrist at Mayo Clinic’s Rochester campus. We’ll review the typical central nervous system effects of high dose loperamide and the associated safety issues. Specific topics: Current status of the opioid crisis in the U.S. Effects of loperamide in both therapeutic and excessive doses Reasons behind taking high dose loperamide in excessive doses Safety issues associated with high dose loperamide Potential of high dose loperamide leading to drug dependence Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 1, 2021
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COVID-19 Miniseries Episode 73: Mayo Clinic Q&A – Dissecting COVID-19 Research and Putting Data in Perspective

This episode is shared from Mayo Clinic Q&A and was recorded May 24, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    The number of COVID-19 cases, hospitalizations and deaths in the U.S. continues to decline. However, cases of COVID-19 are increasing in younger populations.  "It's becoming a childhood disease," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Children have composed over 16,000 hospitalizations for COVID-19 and about 300 have died." Meanwhile, each day brings fresh research news, including updates on possible side effects of the COVID-19 vaccines.  "We're collecting information as we go and have data on about 4.5 million people now," says Dr. Poland. "That's larger than we would have for any other vaccine."  In this Mayo Clinic Q&A podcast, Dr. Poland expands on these latest news items and puts the data in perspective. He also discusses vaccination rates, the possibility of mixing and matching vaccines for COVID-19 boosters, vaccination rates, and much more. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 28, 2021
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Regenerative Medicine Edition Ep.5: The Mission for Fluency and Safeguarding Patients from Stem Cell Tourism

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Saranya Wyles, M.D. (@SWylesMDPhD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Much of regenerative medicine is relatively new and some of the future treatment capabilities have the potential to significantly change the way we practice medicine. How do you educate established clinicians as well as clinicians in training regarding this new practice? How do you educate the general public which has been misled by a variety of false claims regarding which medical conditions regenerative medicine can currently effectively treat? This podcast discusses how a relatively new medical field puts together an education program to inform others of its potential. Our guest is Saranya Wyles, M.D., a resident in the Department of Dermatology who has considerable experience in regenerative medicine education.  Specific topics discussed: Specific groups who need educating regarding the capabilities of regenerative medicine The importance in training the medical workforce regarding regenerative medicine What regenerative medicine means for the next generation of healthcare providers How to incorporate regenerative medicine concepts into an established medical school curriculum How to educate more advanced learn years such as residents and healthcare providers Obtaining an advanced degree in the field a regenerative medicine Additional resources: International Society for Stem Cell Research (ISSCR): https://www.isscr.org/ The ISSCR Patient Handbook on Stem Cell Therapies: https://www.closerlookatstemcells.org/patient-resources/ Regenerative medicine curriculum for next-generation physicians: https://www.nature.com/articles/s41536-019-0065-8 Digital regenerative medicine and surgery pedagogy for virtual learning in the time of COVID-19: https://www.futuremedicine.com/doi/full/10.2217/rme-2020-0106 Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 27, 2021
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COVID-19 Miniseries Episode 72: Mayo Clinic Q&A – Guidelines and Nuances of Wearing a Face Mask

This episode is shared from Mayo Clinic Q&A and was recorded in May, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    Recent COVID-19 masking guidelines announced by the Centers for Disease Control and Prevention, continue to generate a public conversation. "The decision about masking needs to be nuanced," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Wearing a mask should be based on the risk of infection, the percentage of the population vaccinated, a person's own immune system, and then the role of vaccine variants with the durability of our immune response." In this Mayo Clinic Q&A podcast, Dr. Poland discusses masking guidelines in further detail. Also, he offers an update on COVID-19 vaccine research for children, and he shares positive news about the decreasing numbers of COVID-19 cases and deaths. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 26, 2021
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The M.I.A.M.I. Approach to Deciphering Lymphadenopathy

Guest: Carrie A. Thompson, M.D. (@CaThompsonMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) It’s common for a patient to see their primary care provider after they’ve discovered an enlarged lymph node and they’re usually concerned that it represents a serious illness. Fortunately, in most cases it’s due to a benign cause and most patients can be reassured once we perform a careful history and physical examination. However, on occasion lymphadenopathy can represent serious disease. Carrie Thompson, M.D. a hematologist, at Mayo Clinic’s Rochester campus joins us to discuss how to tell when lymphadenopathy is due to a benign or serious cause. We’ll review the characteristics of both benign and malignant lymph nodes and the evaluation which should be done both for an enlarged solitary lymph node as well as generalized lymphadenopathy. Specific topics discussed: Prevalence of malignancy in patients who seek a medical evaluation for lymphadenopathy Categories of disease which can have associated lymphadenopathy Characteristics of benign and malignant lymph nodes Diagnostic approach for a solitary enlarged lymph node Diagnostic approach or multiple or generalized lymphadenopathy Fine needle aspirate vs. excisional biopsy for evaluation of lymphadenopathy Additional resources: Gaddey, HL. Riegel, AM. Unexplained lymphadenopathy: evaluation and differential diagnosis. Am Fam Physician.2016 December 1; 94(11): 896-903. https://www.aafp.org/afp/2016/1201/p896.html Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 25, 2021
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Regenerative Medicine Edition Ep.4: The Curative Potential of Immunotherapy

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Saad J. Kenderian, M.B., Ch.B. (@kenderian_ss) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Regenerative immunotherapy is a treatment that uses the power of our own immune system to fight malignancy. It can include targeted antibodies, cancer vaccines, or tumor infecting viruses to name a few. Some immunotherapy treatments use genetic engineering to enhance our immune cell’s cancer fighting properties and can be used in combination with more traditional treatments including surgery, chemotherapy, or radiation. It’s FDA-approved as a first line treatment of multiple cancers and may also be effective in the management of malignancies that have been resistant to more traditional therapy. This podcast will address regenerative immunotherapy with Dr. Saad Kenderian, a hematologist at the Mayo Clinic. We’ll review the relationship between cancer and our immune system, how we can use our immune system to treat malignancy and which malignancies which have shown the best responses to regenerative immunotherapy.  Specific topics discussed: Relationship between cancer and our immune system How we can use our body’s immune system to fight malignancy Malignancies which can be currently be effectively treated with regenerative immunotherapy Malignancies which have had the best responses to regenerative immunotherapy Limitations in regenerative immunotherapy  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
May 20, 2021
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Identifying Breast Cancer in Men

Guest: Kathryn J. Ruddy, M.D. (@KathrynRuddyMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Breast cancer in men is very uncommon, about 1/100th as common as in women. It’s expected that this year, just under 3000 men are likely to be diagnosed with it, and just over 500 men will die from breast cancer. Because it’s so uncommon, there are very few good studies which have been completed to educate us about this disease. Kathryn Ruddy, M.D., an oncologist at Mayo Clinic’s Rochester campus joins us to discuss breast cancer in men and what we should do as primary care clinicians to care for our male patients who may be at increased risk to develop it. We’ll cover how breast cancer in males differs from that in females, its risk factors, how it’s diagnosed, and the survival rates of men with a diagnosis of breast cancer. Specific topics: Prevalence of breast cancer How most breast cancers in men are found The recommended evaluation of a male patient with suspected breast cancer Risk factors for breast cancer in men Treatment for male breast cancer Survival rates for breast cancer in men Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 18, 2021
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Regenerative Medicine Edition Ep.3: Perspectives in Reconstructive Surgery

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Richard E. Hayden, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Currently reconstructive surgery involves taking the patient’s tissue from one area of their body and using it elsewhere to rebuild diseased or damaged tissue. Regenerative reconstructive surgery will allow the patient to grow their own replacement tissue from stem cells. This has incredible potential for allowing significantly better reconstructive surgical results. Currently regenerative reconstructive surgery is in its infancy, however in the next several years this should develop into a new standard of care for patients who need reconstructive surgery. This podcast features Dr. Richard Hayden, a reconstructive surgeon/otolaryngologist. We discuss the future of reconstructive surgery using regenerative medicine techniques, the difficulties in enabling patient access to regenerative therapies, the education that’s needed for not only providers but also for patients, and the future of regenerative reconstructive surgery. Specific topics discussed: Role regenerative medicine plays and reconstructive surgery Importance in adopting and delivering regenerative care Challenges in current standard of care approaches in reconstructive surgery Difficulties enabling patient access to regenerative therapies Educational needs in regenerative reconstructive surgery The future of regenerative reconstructive surgery Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 13, 2021
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What You Need to Know About Eustachian Tubes and Tonsils

Guest: Laura J. Orvidas, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Tonsils and eustachian tubes often get taken for granted until they cause problems. Eustachian tube dysfunction is quite common and usually resolves on its own, however some patients will develop recurrent eustachian tube dysfunction and it can result in recurrent episodes of otitis media, especially in children. Although recurrent tonsillitis used to be the most common indication for tonsillectomy, more children are having this procedure for disordered breathing conditions, such as obstructive sleep apnea. In this episode, we’ll discuss disorders of the eustachian tube and tonsils with Laura J. Orvidas, M.D., an otolaryngologist at the Mayo Clinic. Specific topics discussed: Purpose of the eustachian tube Definition of eustachian tube dysfunction Physical exam findings of eustachian tube dysfunction Recurrent eustachian tube dysfunction in children and potential for recurrent episodes of otitis media When pressure equalization tubes are indicated Relationship between pharyngitis and tonsillitis Viral versus bacterial causes of tonsillitis How to suspect a peritonsillar abscess Indications for tonsillectomy Management of tonsil stones Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 11, 2021
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COVID-19 Miniseries Episode 71: Mayo Clinic Q&A – Ramping up COVID-19 Vaccination Rate in Race Against Virus

This episode is shared from Mayo Clinic Q&A and was recorded in May 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: DeeDee Stiepan (@deedeestiepan) COVID-19 cases are falling in the U.S. because 245 million doses of one of the available COVID-19 vaccines have been administered, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "But at the same time, there are still people who need more information about the safety and the value of getting a COVID-19 vaccine," says Dr. Poland. While still hopeful, Dr. Poland says he's concerned herd immunity won't be reached in the U.S. through vaccination. And that will mean more tragic deaths due to COVID-19 infection. "My guess is, because we're such an interconnected global community until everybody's safe, none of us are safe. And we're going to likely see continued circulation of the virus, and that virus will seek out whoever is not immune," says Dr. Poland. In this Mayo Clinic Q&A podcast, Dr. Poland also addresses when we will need COVID-19 vaccine boosters will be needed and the latest on masking guidelines from the Center for Disease Control and Prevention. Plus, he will provide an update on COVID-19 treatments and how to handle those who want to visit a newborn baby. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 7, 2021
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Regenerative Medicine Edition Ep.2: Between Hype and Hope – What’s Really Possible?

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Dennis Wigle, M.D., Ph.D. (@DrWigle) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Regenerative Medicine has some amazing capabilities and in the near future, it’s likely to significantly change how we practice medicine. It faces some challenges in educating both the medical community as well as the general public regarding its current realistic capabilities. There are many unsubstantiated claims made by practitioners to the public regarding the benefits of regenerative medicine therapy. We’ll discuss how the true potential of regenerative medicine is conveyed to both clinicians and the public with Dr. Dennis Wigle, a thoracic surgeon and chair of the Division of General Thoracic Surgery at the Mayo Clinic. We’ll discuss some of the common misperceptions of regenerative medicine and how a consultation service can educate both the public and medical community regarding the benefits of regenerative medicine. Specific topics discussed: How to provide education to the public and the medical community When and why the regenerative consultation service was formed How the regenerative medicine consultation service works Common misperceptions community regarding the realistic benefits of regenerative medicine  Additional resources: For more information about Mayo Clinic’s Regenerative Medicine Consult Service, visit: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/regenerative-medicine-consult-service  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 6, 2021
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Regenerative Medicine Edition Ep.1: Transforming Care Towards Curative Solutions

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Fredric B. Meyer, M.D.; Andre Terzic, M.D., Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Imagine a patient who has suffered a massive myocardial infarction leaving a significant amount of damaged and non-functioning ventricular myocardium. Treatment for this patient’s subsequent congestive failure does not involve diuretics and beta blockers but rather an injection of the patient’s modified stem cells into surrounding viable ventricular myocardium resulting in the regeneration of new, functioning myocardial cells restoring the cardiac output. This is not science fiction but represents ongoing work by investigators in Regenerative Medicine. This week’s podcast will explore this amazing field of medicine which has the potential to change how medicine is practiced. We’ll discuss the origins of regenerative medicine, what currently be done in regenerative medicine as well as the potential for the future. Our guests today are Andre Terzic, M.D., Ph.D., director of the Mayo Clinic Center for Regenerative Medicine and Fredric B. Meyer, M.D., a neurosurgeon and the Executive Dean for Education at the Mayo Clinic.  Specific topics discussed: When the field of regenerative medicine began Which current medical conditions can currently be managed with regenerative medicine How to determine which patients have potential for regenerative medicine therapies Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 4, 2021
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Mayo Clinic Q&A: COVID-19 Vaccine Confidence and the Importance of That Second Dose

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  While the number of people being vaccinated for COVID-19 is dropping, the Centers for Disease Control and Prevention and other medical experts continue to strongly encourage people to get vaccinated for COVID-19. And that means that those who are being vaccinated with the Moderna and Pfizer COVID-19 vaccine should get their first and second doses on schedule. “About 8% of people who got their first dose have not returned for the second dose and this is concerning when you're getting close to 1 in 10," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "When you measure in the short term, one dose in a healthy person offers about 80% protection. But that's not 95% protection, like you get after two doses." In this Mayo Clinic Q&A podcast, Dr. Poland expands on why people need that second COVID-19 vaccine dose and he talks about whether people should mix and match the different COVID-19 vaccines for their second dose. He also speaks about the status of COVID-19 vaccines for young people, and he addresses listener questions about traveling, being together after vaccination, and the latest rise of additional COVID-19 variants. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 29, 2021
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Fact or Fiction: Erectile Dysfunction Treatments

Guest: Tobias S. Kohler, M.D., M.P.H. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Erectile dysfunction not only causes lifestyle changes, but it may also be the first symptom of peripheral vascular disease. Since many men are reluctant to mention erectile dysfunction to their healthcare provider, it’s important for us to ask our patients whether it is a problem and be knowledgeable in the appropriate evaluation of patients who have it. This reluctance may cause many to seek out readily available but ineffective treatments from questionable sources, even though there are a variety of proven, effective treatments that can be prescribed. Tobias S. Kohler, M.D., M.P.H., a Mayo Clinic Urologist, joins us to discuss the impact of erectile dysfunction, the currently available effective treatments, as well as the unproven, ineffective products currently being used. Specific topics discussed: The first historical appearance of treatments for erectile dysfunction Most common causes of dysfunction Appropriate evaluation of patients who present with erectile dysfunction Review of the currently available effective treatment options Reasons men are reluctant to mention the topic of erectile dysfunction to their provider Review of some ineffective treatments currently being promoted Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 27, 2021
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COVID-19 Miniseries Episode 70: Mayo Clinic Q&A – Breakthrough COVID-19 Infections and Booster Vaccines

This episode is shared from Mayo Clinic Q&A and was recorded on April 19, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group says COVID-19mutations and the virus spread are happening because of people who don't wear masks, who don't get vaccinated and who don't adhere to safety recommendations. "I believe that we should be radically transparent and honest," says Dr. Poland. "The more time this virus passes through one person after another, the more likely it continues to mutate. As a result of those mutations, two things are happening. Some of the mutations are making vaccines and plasma monoclonal antibodies less effective. The other thing is that the virus will likely become something that we have to live with for the rest of our lives." Dr. Poland reminds people that vaccine protection is not 100%. Breakthrough infections can occur. "Remember that in the clinical trials, 95% means that compared to unvaccinated people, your risk is reduced by 95% — not 100%," he says. "You might have a mild case of COVID-19,but you can still spread it to others, including those who are immune compromised, such as cancer patients. That's why we continue to wear masks until we get very widespread immunization." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about breakthrough infections and the Johnson & Johnson COVID-19 vaccine pause, and he answers listeners' questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 22, 2021
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Mayo Clinic Q&A: On the Verge of Another COVID-19 Surge

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    As spring break travelers return home and the highly transmissible U.K. COVID-19 variant is discovered in all 50 U.S. states, the country is on the verge of a fourth COVID-19 pandemic surge. That's according to a number of health experts, including Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.   However, Dr. Poland says there is some good news related to the transmission of COVID-19 on surfaces.  "Wisdom resides in changing your mind and your recommendations as new data and science becomes available," says Dr. Poland. "What the Centers for Disease Control and Prevention is doing is modifying those guidelines, saying that the risk of touching a contaminated surface and then getting infected is very low." In this Mayo Clinic Q&A podcast Dr. Poland explains more about the CDC guidelines and he addresses other COVID-19 topics in the news, including recent data that says men are more vaccine-hesitant than women. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 21, 2021
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Utilizing Artificial Intelligence to Evaluate Dizziness

Guest: Devin L. McCaslin, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Being dizzy means different things to different patients and most patients find dizziness difficult to describe. Providers find it difficult to evaluate patients with dizziness and also which specialties can be asked for help in managing the dizzy patient. Dr. Devin McCaslin is the Director of the Vestibular and Balance Laboratory at the Mayo Clinic and an expert in evaluating the dizzy patient. He will discuss such topics as the role of vestibular balance laboratory testing in assessing patients, the most common findings from these evaluations, the multi-disciplinary approach to evaluating patients with dizziness, and how artificial intelligence is being used in the evaluation of a patient complaining of dizziness. Specific Topics Discussed: The multi-disciplinary approach to evaluating patients complaining of dizziness. Most common findings in the evaluation of a patient with dizziness. The role of vestibular balance laboratory testing in assessing patients who are candidates for these tests. How artificial intelligence is being used in the evaluation of patients with dizziness. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 20, 2021
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Mayo Clinic Q&A: Vacation Travel, Vaccines for Teens and More COVID-19 News

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    If you're fully vaccinated for COVID-19 you can travel domestically and where travel is allowed internationally, according to new interim travel guidelines from the Centers for Disease Control and Prevention (CDC). Even with those recommendations the CDC continues to recommend not traveling unless it is essential. Regardless, the CDC strongly recommends people continue to wear a face mask, practice social distancing and sanitize their hands. Meanwhile, COVID-19 vaccine research is continuing in teenagers. "The early data show equal safety in young people aged 12 to 16," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "I think this is going to imply that, somewhere between this fall and Christmas, we're going to be able to offer the (COVID-19) vaccine to every age group." In this Mayo Clinic Q&A podcast, Dr. Poland answers a number of listener questions, including how long the COVID-19 vaccines are predicted to last and if the current transmission research still supports wiping down household items. Dr. Poland also explains why someone who has had COVID-19 should still get a COVID-19 vaccine. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 19, 2021
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This Podcast Will Make Your Head Spin

Guest: Scott D. Eggers, M.D. (@sdze) Host: Darryl S. Chutka, M.D. (@ChutkaMD)  The complaint of dizziness is a common symptom our patients experience. It has a variety of causes; fortunately, most of them are benign. Despite the fact we frequently see patients with this medical concern, we still struggle evaluating them. Part of the difficulty is that dizziness means different things to different people and the cause of dizziness can be caused by disorders in one of several organ systems. To help us evaluate dizziness, Dr. Scott Eggers, a neurologist at the Mayo Clinic, reviews why dizziness is so difficult to evaluate and how we should evaluate a patient who complains of dizziness. We also explore the most common causes of dizziness including benign positional vertigo and vestibular neuritis. Finally, Dr. Eggers reviews symptoms that are suspicious for an ominous cause of dizziness. Specific topics discussed: Why dizziness is difficult to evaluate How to evaluate the complaint of dizziness Most common causes of dizziness Dizziness symptoms which are ominous for serious disease Description of benign positional vertigo Description of vestibular neuritis Description of vestibular migraines Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 13, 2021
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COVID-19 Miniseries Episode 69: Post-Acute COVID-19 and Central Sensitization

Central sensitization (CS) describes pathophysiologic changes in the central nervous system, including alterations in neurochemistry, CNS receptors, endogenous opioid system hyperactivity, cytokine and HPA axis dysregulation, and sympathetic hyperactivity. Collectively, these changes result in amplification of pain and sensory signals, leading to widespread pain, fatigue and other sensory sensitivities. Fibromyalgia and Chronic Fatigue Syndrome are established diagnoses/manifestations of central sensitization. In the era of the COVID-19 pandemic, we continue to learn about Post-Acute COVID-19 Syndrome, a manifestation of central sensitization similar to other post-infectious forms of CS, which underlies the persistent symptoms that many people experience after initial recovery from COVID-19. Elizabeth C. Wight, M.D. joins us to talk about Mayo Clinic’s treatment approach to central sensitization, which is rooted in empowering patients with education and a framework for a self-management program. This includes stress management, moderation, positive thinking, decreasing focus on symptoms, sleep hygiene, and Cognitive Behavioral Therapy among others. Additional resources: Post-COVID Recovery on Mayo Clinic Connect: https://connect.mayoclinic.org/page/post-covid-recovery/ Mayo Clinic’s “A Systematic Approach to Medically Unexplained Symptoms 2021” course can be found at https://ce.mayo.edu/internal-medicine/content/systematic-approach-medically-unexplained-symptoms-2021#group-tabs-node-course-default1 Clauw DJ. Fibromyalgia: A clinical review. JAMA. 2014;311(15):1547-1555. doi:1001/jama.2014.3266 Clauw DJ. Fibromyalgia and related conditions. Mayo Clin Proc. 2015 May;90(5):680-92. https://doi.org/10.1016/j.mayocp.2015.03.014 Harte, SE, Harris, RE, Clauw, DJ. The neurobiology of central sensitization. J Appl Behav Res. 2018; 23(2): e12137. https://doi.org/10.1111/jabr.12137 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 6, 2021
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Your Patient Has a Thyroid Nodule – What Now?

Guest: Jan L. Kasperbauer, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Thyroid nodules are commonly found in patients by primary care providers, either by physical exam or incidentally by a variety of imaging studies. Fortunately, the vast majority of thyroid nodules are benign, however as primary care providers we need to be comfortable in evaluating them to rule out the possibility that they represent a thyroid cancer. Joining us is Dr. Jan Kasperbauer, an otolaryngologist at the Mayo Clinic. We discuss risk factors for thyroid cancer, how a primary care provider should evaluate and manage patients with thyroid nodules, various types of thyroid cancer, and treatment options as well as the recommended follow-up for patients with thyroid cancer. Specific topics discussed: Risk factors for thyroid cancer Detecting thyroid cancers How primary care provider should evaluate and manage patients with thyroid nodules Review of the various types of thyroid cancer Treatment options for thyroid cancer Recommendations for primary care providers in following patients with treated thyroid cancer Additional resources: Classification for risk stratification and follow up recommendations: Grant, EG, et al. Thyroid ultrasound reporting lexicon: white paper of the ACR thyroid imaging, reporting and data system (TIRADS) committee. J Am Coll Radiol. 2015 Dec; 12(12): 1272-1279. doi: https://doi.org/10.1016/j.jacr.2015.07.011 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 30, 2021
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Mayo Clinic Q&A: Viruses Cannot Mutate If They Cannot Replicate

This episode is shared from Mayo Clinic Q&A and was recorded in March, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  The COVID-19 virus mutates and replicates when people let down their guard and don't follow safety protocols, such as practicing social distancing and wearing a mask.  "I think most of us expect a major surge because of spring break travel and the relaxation of restrictions," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And the sort of COVID fatigue that all of us feel, in one way or another." In this Mayo Clinic Q&A podcast, Dr. Poland addresses the potential of a fourth COVID-19 surge, new information regarding the COVID-19 vaccines for pregnant women and he discusses research for next generation vaccines for COVID-19 variants. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 26, 2021
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COVID-19 Miniseries Episode 68: Skin Integrity in Patients with COVID-19

Guest: Jennifer L. Elmer, APRN, CNS, D.N.P.; Brianna M. Skrukrud, APRN, C.N.P. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Pressure injuries in bedridden patients present significant challenges​, which are compounded in the patient with a COVID-19 diagnosis. In this episode we discuss the problems encountered in preventing, diagnosing, and managing skin alterations in patients with COVID-19. Jennifer L. Elmer, APRN, CNS, D.N.P. and Brianna M. Skrukrud, APRN, C.N.P., two wound care experts at Mayo Clinic, discuss situations ​in which, despite best efforts, pressure injuries are unavoidable and why COVID-19 poses a great risk for skin alterations in hospitalized patients. They also discuss the 2020 position statement of National Pressure Injury Advisory Panel (NPIAP) on the management of skin alterations during the COVID-19 crisis. Additional resources: Unavoidable Pressure Injury during COVID-19 Pandemic: A Position Paper from the National Pressure Injury Advisory Panel https://cdn.ymaws.com/npiap.com/resource/resmgr/white_papers/Unavoidable_in_COVID_Pandemi.pdf Skin Manifestations with COVID-19: The Purple Skin and Toes that you are seeing may not be Deep Tissue Pressure Injury https://cdn.ymaws.com/npiap.com/resource/resmgr/white_papers/COVID_Skin_Manifestations_An.pdf Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 23, 2021
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Mayo Clinic Q&A: Rapid Pace of COVID-19 Vaccinations

This episode is shared from Mayo Clinic Q&A and was recorded in March 2021.  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: DeeDee Stiepan (@deedeestiepan)  Millions of people in the U.S. are being vaccinated for COVID-19. However, discussion is ongoing as to whether people who are immunocompromised, such as patients undergoing cancer treatment, or people who have autoimmune diseases, should be vaccinated for COVID-19.  "Both of those categories (of people) should be vaccinated," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Those are not contraindications. Those are indications to get the vaccine." He adds that research is ongoing, but current information demonstrates the benefits far outweigh the theoretical risks.  In this Mayo Clinic Q&A podcast, Dr. Poland talks about vaccine hesitancy, and patients who are immunocompromised or have autoimmune conditions. Also, he discusses next steps in the journey to vaccinate children for COVID-19. And he reviews recent guidance from the Centers for Disease Control and Prevention Control about in-person gatherings.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 19, 2021
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Can We Prevent Suicide?

* WARNING: This episode discusses suicide and suicidal ideation. * Guest: J. Michael Bostwick, M.D.(@DrBostwick) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) In this episode, professor of psychiatry and international authority on suicide risk and challenges in suicide prevention, J. Michael Bostwick, M.D.  from Mayo Clinic in Rochester joins us. He’ll discuss epidemiological-based research looking at the utilization patterns of medical care by individuals who have contemplated or committed suicide. Dr. Bostwick will describe the concept of suicide crisis including risk factors, current events/warning signs, and mental status/agitation. He’ll also explain self-agency, stigma of discussing mental illness, potential value-based societal approach to individuals in distress and despair, and potential solutions to the suicide prevention. Additional resources: Suicide Prevention in Primary Care Medicine; Huguet, Nathalie et al.; Mayo Clinic Proceedings, Volume 90, Issue 11, 1459 – 1461; https://doi.org/10.1016/j.mayocp.2015.09.011 Grappling With Suicide Risk; Sublette, M. Elizabeth; Mayo Clinic Proceedings, Volume 93, Issue 6, 682 – 683; https://doi.org/10.1016/j.mayocp.2018.04.006 Suicide Attempt as a Risk Factor for Completed Suicide: Even More Lethal Than We Knew; Bostwick, J. Michael et al.; Amer Journal of Psychiatry; Volume 173, Issue 11, November 01, 2016, 1094-1100; https://doi.org/10.1176/appi.ajp.2016.15070854 If you're feeling overwhelmed by thoughts of not wanting to live or you're having urges to attempt suicide, get help now. Call 911 or your local emergency number immediately. Call a suicide hotline. In the U.S., call the National Suicide Prevention Lifeline at 1-800-273-8255 any time of day — press "1" to reach the Veterans Crisis Line or use Lifeline Chat. For a list of suicide hotline numbers outside of the U.S., visit: https://www.opencounseling.com/suicide-hotlines Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 18, 2021
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Mayo Clinic Q&A: “Brain Fog” is a Lingering Condition for Many COVID-19 Long-Haulers

This episode is shared from Mayo Clinic Q&A and was recorded in March, 2021.  Guest:  Billie A. Schultz, M.D.  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  Fatigue and what's being called "brain fog" are turning out to be some of the most common issues for long-hauler patients recovering from COVID-19. The National Institutes of Health calls these and other symptoms, which can last for several months, post-acute sequelae of SARS-CoV-2, or PASC. Those suffering from brain fog may experience short-term memory loss, confusion, difficulty concentrating, or just feeling different than they did before they had COVID-19, even if it was a mild case of the infection.  And Dr. Billie Schultz, a Mayo Clinic physical medicine and rehabilitation expert, says, though older patients more often to have these symptoms more often, younger people are also showing up with brain fog. In this Mayo Clinic Q&A podcast, Dr. Schultz says brain fog seems to be more inflammatory than infection, but there are more questions than answers about this neurological concern. Meanwhile, efforts are underway to develop rehabilitation programs to help patients recover. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 17, 2021
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COVID-19 Miniseries Episode 67: Finding a Solution for Every Long-Hauler

Guest: Ravindra Ganesh, M.B.B.S., M.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) It has been estimated that as many as 10-30% of patients who have recovered from COVID-19 have an array of symptoms, ranging from minor to disabling, that persist more than four weeks post-COVID infection. These symptoms have not only been identified in patients who had severe symptoms of COVID-19 requiring intensive care unit treatment, but also those who only experienced mild-to-moderate symptoms. The exact cause of this state, most popularly called post-COVID long hauler syndrome, is still under investigation. The symptoms range from mild to disabling fatigue, body aches, atypical chest pain, loss of sense of taste and smell, brain fog, among others and many of these patients need additional evaluation and management to deal with their disabling symptoms. In this podcast Dr. Ravindra Ganesh, the consultant in General Internal Medicine who leads the COVID Frontline Care Team (CFCT) efforts, as well as the Post-COVID Clinic, at Mayo Clinic Rochester, discusses the array of symptoms, management strategies, and research possibilities, as well as opening of an upcoming clinic in Mayo Clinic Rochester that would address the concern of the patient's and deal with the post COVID long hauler symptoms Additional Resources: Post-COVID Syndrome on Ask Mayo Expert: https://askmayoexpert.mayoclinic.org/  To refer a patient to or request an appointment at Mayo Clinic, visit: https://www.mayoclinic.org/appointments  Post-COVID Recovery on Mayo Clinic Connect: https://connect.mayoclinic.org/page/post-covid-recovery/  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 16, 2021
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Clostridium Difficile Infection: You Want to Transplant What?!

Guest: Maria I. Vazquez Roque, M.D. (@MVazquezRoqueMD)  Host: Darryl S. Chutka, M.D. (@ChutkaMD)  Clostridium difficile is a toxin-producing bacterium that can result in a severe form of antibiotic-associated diarrhea known as clostridium difficile infection or CDI. Cases can vary from mild diarrhea to severe colitis that at times can be fatal. There’s been a dramatic increase in the number as well as severity of CDIs in the U.S. over the past 20 years. Although CDI typically occurs following the use of antibiotics, it can also be spread from one individual to another, especially in hospitals and skilled nursing facilities. Antibiotics have been the traditional treatment for patients with CDI, however recurrent symptoms have been a problem. There’s now a new treatment for CDI, felt to be effective in over 90% of patients with the illness. Our guest to discuss this topic is Dr. Maria Vazquez Roque, a gastroenterologist at the Mayo Clinic. We’ll review the common presenting symptoms, laboratory tests needed to establish a diagnosis, and the current recommendations for treatment including the latest of fecal transplantation.  Additional resources:  Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): https://doi.org/10.1093/cid/cix1085  Specific topics discussed: The typical presentation of C. difficile infection Patients who are at increased risk for a C. difficile infection Laboratory tests to order to confirm a case of C. difficile infection Treatment options for C. difficile infection including fecal transplantation Potential benefit of probiotics for preventing a C. difficile infection Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 9, 2021
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Mayo Q & A: COVID-19 Variants and the Evolving Science

This episode is shared from Mayo Clinic Q&A and was recorded in February, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    People may be curious, confused or critical of what seem to be changing messages related to the COVID-19 pandemic. Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, reminds folks that messages change because data changes and the science evolves. "As we learn new science, we use that science to modify our recommendations," says Dr. Poland. "It's not that scientists are flip-flopping. It is that new data allows us to begin expanding those recommendations." For instance, COVID-19 cases and deaths in the U.S. are currently declining. But, Dr. Poland says, there are new data predicting the possibility of another surge of COVID-19 infections in March because of U.K. variant transmission. In this Mayo Clinic Q&A podcast Dr. Poland talks about several issues, including the U.K. variant, vaccine development and the public’s COVID-19 fatigue. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 3, 2021
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COVID-19 Miniseries Episode 66: Monoclonal Antibody Treatment for COVID-19

Guest: Ravindra Ganesh, M.B.B.S., M.D. and Raymund R. Razonable, M.D.  Host: Amit K. Ghosh, M.D. (@AmitGhosh006)  In this episode, Ravindra Ganesh, M.B.B.S., M.D. and Raymund R. Razonable, M.D. join Amit K. Ghosh, M.D. to review the use of monoclonal antibody as a new antiviral agent in the treatment of COVID-19 infection.  Who is most likely to benefit from monoclonal antibody infusions? Drs. Ganesh and Razonable, discuss recent studies on monoclonal antibody infusions in patients with mild to moderate COVID-19 infections. Also discussed are the logistical challenges faced and the innovative solutions that were implemented while administering this therapy, particularly navigating the acceptance of treatment, its real and perceived side effects, and lack of awareness due to inequity and poverty. Research on the development of subcutaneous or intramuscular administration for prophylaxis against COVID-19 in patients at high risk for complications or at high risk for being exposed to SARS-CoV-2 is also discussed in this episode.  Additional resources:  AskMayoExpert COVID-19 Navigator: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Weinreich DM, Sivapalasingam S, Norton T, et al. REGN-COV2, a neutralizing antibody cocktail, in outpatients with Covid-19. N Engl J Med 2021;384:238-251.  Chen P, Nirula A, Heller B, et al. SARS-CoV-2 neutralizing antibody LY-CoV555 in outpatients with Covid-19. N Engl J Med 2021;384:229-237.  Gottlieb RL, Nirula A, Chen P, et al. Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial.JAMA. Published online January 21, 2021. doi:10.1001/jama.2021.0202  An EUA for Bamlanivimab—A Monoclonal Antibody for COVID-19. JAMA. Published online December 11, 2020. doi:10.1001/jama.2020.24415  Monoclonal Antibodies: Update on this COVID-19 Experimental Therapy  https://discoverysedge.mayo.edu/2021/02/17/monoclonal-antibodies-update-on-this-covid-19-experimental-therapy/  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 2, 2021
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COVID-19 Miniseries Episode 65: Restoring Function for Long-Haulers

Guest: Greg Vanichkachorn, M.D., M.P.H. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) For some patients who have had COVID-19, symptoms of the disease may last long after the infection is over. Long-haulers syndrome due to COVID-19 could include profound fatigue, shortness of breath, and long-term neurological complaints, including headache, dizziness, or weakness. Mayo Clinic has launched the COVID Activity Rehabilitation Program, or CARP, to help these patients return to daily life and work. CARP is not just for folks who are trying to get back to work, but for anyone trying to get back to their baseline life. In this episode, Dr. Greg Vanichkachorn, a Mayo Clinic preventive, occupational and aerospace medicine specialist who leads the CARP program, gives an overview of COVID long haulers and how post-COVID symptoms affects patients. He also shares the goals and results of Mayo Clinic CARP program. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 16, 2021
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Answers From the Lab: The Impact of COVID-19 Variants

This episode is shared from Answers from the Lab and was originally published February 2, 2021.  Guest: Matthew J. Binnicker, Ph.D. (@DrMattBinnicker) Host: William G. Morice, II M.D., Ph.D. (@moricemdphd) Matthew Binnicker, Ph.D., vice chair of practice for Mayo Clinic's Department of Laboratory Medicine and Pathology, joins William Morice II, M.D., Ph.D., president of Mayo Clinic Laboratories, for this week's "Answers From the Lab" leadership update. In this episode, Dr. Binnicker and Dr. Morice discuss the impact that emerging COVID-19 variants could have on virus testing, vaccine and spread. For more, follow the Mayo Clinic Labs on Twitter @mayocliniclabs or visit https://news.mayocliniclabs.com/podcast/answers-from-the-lab/ to check out all of their episodes.
February 9, 2021
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COVID-19 Miniseries Episode 64: Leveraging Community Care for Scalable Outpatient Management of COVID-19

Guest: Ravindra Ganesh, M.B.B.S., M.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) The Mayo Clinic COVID Frontline Healthcare Team (CFCT) is an integrated team comprised of doctors and support staff, including nurses, remote monitoring technicians, medical assistants, and desk staff. These teams are responsible for evidence-based management of all newly diagnosed COVID-19 patients. We’re joined by CFCT Codirector Ravindra Ganesh, M.B.B.S., M.D., to discuss the essential roles of CFCT’s during the pandemic. Topics include how they: Notify all patients who receive a COVID positive test result in Mayo/Mayo Clinic Health service in the Midwest region through phone call or portal messaging with attached questionnaire Conduct outpatient monitoring and follow-up as well as identify patient at high risk for decompensation Prevent COVID positive patients from coming to the Mayo Clinic facilities by remote monitoring and risk assessment Reinforce social isolation recommendations from public health to all COVID positive patients and assess safety to come off isolation Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 9, 2021
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COVID-19 Miniseries Episode 63: Mayo Clinic Q&A – #AskTheMayoMom about Sports Participation During COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in February, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  David B. Soma, M.D. (@DrDaveSoma); Talha Niaz, M.B.B.S. Host: Angela C. Mattke, M.D. (@DrAngelaMattke) There are many benefits to sports participation for children and adolescents. However, during the COVID-19 pandemic, activities such as youth sports have been put on hold or modified to decrease the spread of COVID-19. Also, the scientific community is learning about when it is safe to return to sports participation following COVID-19 infection.   On the Mayo Clinic Q&A podcast, "Ask the Mayo Mom" host and Mayo Clinic pediatrician, Dr. Angela Mattke is joined by Dr. David Soma, a pediatric sports medicine physician at Mayo Clinic Children's Center, to discuss sports participation during the COVID-19 pandemic and what you need to know about return to play after COVID-19 infection. Also joining Drs. Mattke and Soma is Dr. Talha Niaz, a pediatric cardiologist at Mayo Clinic.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
February 8, 2021