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Mayo Clinic Talks

Mayo Clinic Talks

Stay on top of your practice with podcasts from colleagues at Mayo Clinic.

All Episodes

Headache Edition: Migraine Advocacy & Special Considerations in Women

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Amaal J. Starling, M.D. (@AmaalStarlingMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Migraine is four-times more common in women than men and because of migraine predominance in females, it is a significant women’s health issue. Migraine commonly results in loss of productivity and this has a significant economic burden. According to a recent report from the Society for Women’s Health Research, it’s estimated that migraine costs the United States is an estimated $78 billion per year, with women accounting for approximately 80% of the direct medical and lost labor costs.  This podcast will continue our series on headaches and will concentrate on migraine in women. Our guest for this topic is Amaal J. Starling, M.D., a neurologist at the Mayo Clinic in Scottsdale, Arizona. We’ll discuss why migraine is more common in females, how the prevalence changes throughout a woman’s lifetime and specific treatment recommendations for women with migraine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 30, 2022
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Cannabidiol (CBD): Discussing Benefits and Risks with Patients

Guest: Thomas P. Pittelkow, D.O., M.P.H. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Cannabidiol (CBD) is a popular natural remedy used for a variety of common ailments and is one of more than 100 chemical compounds called cannabinoids derived from the cannabis plant. Tetrahydrocannabinol (THC) is the main psychoactive cannabinoid found in cannabis. However, unlike THC, CBD does not have psychoactive properties. There are claims this compound treats not only pain, but a variety of mental health issues, symptoms of malignancy and may even have some cardiovascular benefits. Are all these claims true? What’s been proven? What do we know about the safety of this product? We’ll get the answers to these questions as we discuss Cannabidiol (CBD) with Thomas P. Pittelkow, D.O., M.P.H., an anesthesiologist and pain medicine specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 28, 2022
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Headache Edition: Interdisciplinary Pain Rehabilitation Treatment for Chronic Headache

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Christopher D. Sletten, Ph.D., L.P. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Chronic headache is one of the more challenging medical conditions primary care providers commonly face. Whereas the traditional medical model views pain as a problem to be treated and relieved, this model often fails when dealing with patients experiencing chronic headaches. On the other hand, the bio-psychosocial model fits patients with chronic headache much better and when this model is used in the management, patients often have a much better outcome. This podcast is another in our series of headaches and will address the use of a cognitive-behavioral approach with an interdisciplinary team in the evaluation and management of patients with chronic headaches. Our guest Christopher D. Sletten, Ph.D., L.P., a psychologist at the Mayo Clinic in Jacksonville, Florida. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 23, 2022
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COVID-19 Update

This episode is shared from Mayo Clinic Q&A and was recorded in June 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) As immunity wanes for many vaccinated adults and omicron and its subvariants continue to circulate, it seems that just about everyone knows someone with a case of COVID-19. The steady increase in COVID-19 infections is due to changing, highly contagious variants, explains Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. Dr. Poland says it’s still important to take the precaution of mask-wearing in public areas, even if you have been vaccinated and have received your boosters. "I can’t say it enough. This is so hypercontagious that, regardless of having had three or four doses of vaccine or of having previous COVID-19, you still run an appreciable chance of getting COVID," explains Dr. Poland. "The risk in that case is not of death or hospitalization, but of the complications and long-haul symptoms of COVID-19. And that’s what we’re trying to prevent in people."  For parents, there is positive news this week, as the Food and Drug Administration (FDA) advisory panel voted unanimously to authorize emergency use of the Pfizer and Moderna COVID-19 vaccines for children under 5. For this age group, the Pfizer vaccine will be given in three doses while the Moderna vaccine will be given in two doses. The FDA panel's recommendation now goes to the Advisory Committee on Immunization Practices (ACIP) at the Centers for Disease Control and Prevention for approval before shots can be administered, possibly beginning as early as next week. On the Mayo Clinic Q&A podcast, Dr. Poland shares the latest COVID-19 news, answers listener questions, and discusses another infectious disease outbreak: monkeypox.  
June 22, 2022
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Assessing and Supporting Patients with Alcohol Use Disorder

Guest: Terry D. Schneekloth, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Unhealthy use of alcohol has the potential to affect not only the individual who consumes the alcohol, but a variety of others as well. Alcohol is the most used addictive substance, with an estimated prevalence of 7% of the United States population. Excessive alcohol use has the potential to cause damage to essentially every organ system and is thought to reduce one’s life expectance by approximately 10 years. Whereas treatment is available and has the potential to be very successful, it often requires an ongoing, lifetime of therapy. Our guest for this podcast is Terry D. Schneekloth, M.D., a psychiatrist and addiction medicine specialist at the Mayo Clinic in Scottsdale, Arizona. This podcast discusses when you should suspect alcoholism in your patients, how to make a diagnosis and which management techniques have been shown to be effective. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 21, 2022
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Headache Edition: Migraine Treatment

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Fred (Michael) M. Cutrer, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) It is estimated that nearly 40 million individuals in the United States have migraines and they’re responsible for a significant amount of lost productivity and healthcare costs. The estimates of the economic impact of migraines in the United States alone approaches $36 billion per year. Many of our patients struggle with adequate management of their migraines; healthcare providers are often confused about the many treatment options now available. This podcast will review and clarify the various treatments for migraines, both for abortive therapy as well as prevention. Our guest is Fred (Michael) M. Cutrer, M.D., a neurologist and headache specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 16, 2022
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Managing Patients with Lynch Syndrome

Guest: Eric J. Dozois, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) In the mid-1960’s Dr. Henry Lynch first described a condition characterized as the “cancer family syndrome” in which members of families demonstrated an increased risk of a variety of malignancies. This eventually became known as “Lynch Syndrome”. Lynch Syndrome is a genetic disorder and can be the underlying cause of premature colon cancer as well as other malignancies. There are some clues to its presence and specific recommendations for managing patients with the condition. The topic for this podcast is Lynch Syndrome and we’ll learn more about the disorder from our guest, Eric J. Dozois, M.D., a colorectal surgeon at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 14, 2022
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Headache Edition: Migraine

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Carrie (Beth) E. Robertson, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Migraine represents a major public health problem and is relatively common affecting an estimated 36 million individuals per year. It is much more likely to affect females and typically accounts for up to four million visits to the Emergency Department and over four million outpatient office visits per year. Migraines are most common in women of childbearing age and are associated with a significant loss of productivity, resulting in a major economic impact. In this podcast, we’ll continue our series on headache and will focus on migraine. We’ll review the diagnosis, what’s happening in the brain during a migraine attack and the benefits of lifestyle changes in the management of migraine. Our guest for this episode is Carrie (Beth) E. Robertson, M.D., a neurologist at the Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 9, 2022
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Headache Edition: Approach to the Evaluation of Headache

To claim credit for this episode, visit Mayo Clinic Talks Podcast: Headache Edition - Online CME Course. Guest: Jerry W. Swanson, M.D., M.H.P.E. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Everyone has experienced a headache and for most of us, they are just a minor inconvenience. Unfortunately for some, headaches represent a major health problem. The pain can be intense and may result in major lifestyle changes including sudden change in plans, loss of productivity, and strained relationships. As primary care providers, patients with chronic, recurrent headaches can represent some of the most challenging patients we see. Fortunately, only rarely do headaches represent a serious threat to one’s life, but one still needs to be alert to potential clues indicating the possibility of the headaches representing a serious medical condition. There have also been numerous new treatments available for the management of migraines. This will be the first in a series of podcasts dedicated to the topic of headache. We’re also going to honor one of the Mayo Clinic’s most prestigious physicians in the field of headache. Jerry W. Swanson, M.D., M.H.P.E. has been a neurologist at Mayo for 39 years and has been a specialist in the evaluation and management of patients with headaches. He brings experience and a wealth of knowledge to this topic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 7, 2022
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Pediatric Topics: Evaluation of a Suspected Inborn Error of Metabolism

Guest: Brendan C. Lanpher, M.D. Host: David J. Sas, D.O. (@davidsas1) Inborn errors of metabolism can present in a variety of ways depending on the specific type of disease.  The most critical presentation to identify occurs in the neonatal period when more severe diseases can cause acute decompensation.  These patients require appropriate evaluation and timely, expert management for good outcomes.  Diagnostic testing, including newborn screening, is advancing rapidly as are innovative treatment methods, making this an exciting field for clinicians. The guest for this episode is Brendan C. Lanpher, M.D., a board-certified geneticist at the Mayo Clinic Children’s Center in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 2, 2022
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Women and Depression

Host: Joshua D. Luciew, MPAS, P.A.-C.    Guest: Neeta Jain, M.D. Depression is a common condition that we see in our practices. It is a multifactorial disease that can affect patients of all ages. In this episode, we discuss women and depression, as women are twice as likely as men to receive this diagnosis. We will explore how this condition is diagnosed, depression subtypes, what effect hormones have on a woman’s mental health, and how we can help treat this condition for our patients through various parts of their life. The guest for today’s episode is Neeta Jain, M.D., Mayo Clinic Board Certified Psychiatrist at Mayo Clinic in Arizona. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 31, 2022
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Pediatric Topics: Undescended – Evaluation and Management

Guest: Candace F. Granberg, M.D. (@candacegranberg) Host: David J. Sas, D.O. (@davidsas1) Detection and management of undescended testicles (cryptorchidism) is a common issue for newborn and infant boys.  This episode discusses proper diagnostic techniques for cryptorchidism, including how to distinguish between a retractile testicle and a truly undescended testicle, as well as when to refer infants to a pediatric urologist for further evaluation and management.  Further, we identify the indications for surgical correction and what parents and pediatricians should expect from this surgery. The guest for this episode is Candace F. Granberg, M.D., a board-certified pediatric urologist at the Mayo Clinic Children’s Center in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 26, 2022
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Pediatric Topics: Undescended – Evaluation and Management

Guest: Candace F. Granberg, M.D. (@candacegranberg) Host: David J. Sas, D.O. (@davidsas1) Detection and management of undescended testicles (cryptorchidism) is a common issue for newborn and infant boys.  This episode discusses proper diagnostic techniques for cryptorchidism, including how to distinguish between a retractile testicle and a truly undescended testicle, as well as when to refer infants to a pediatric urologist for further evaluation and management.  Further, we identify the indications for surgical correction and what parents and pediatricians should expect from this surgery. The guest for this episode is Candace F. Granberg, M.D., a board-certified pediatric urologist at the Mayo Clinic Children’s Center in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 26, 2022
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Adrenal Insufficiency: Investigation and Management

Guest: Irina Bancos, M.D. (@IrinaBancos) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Fatigue, weakness, and loss of appetite are very vague and non-specific symptoms, and unfortunately relatively common complaints our patients describe to us. However, they may also be the presenting symptoms of adrenal insufficiency. If untreated, serious complications can develop, the most serious being an adrenal crisis. Adrenal insufficiency is relatively uncommon and unless we think about it, we’re likely to either make a delayed diagnosis or possibly miss the disorder altogether. The topic for this podcast is adrenal insufficiency. We’ll review its symptoms, the recommended evaluation and management with Irina Bancos, M.D., an endocrinologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 24, 2022
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Mayo Clinic Q&A: COVID-19 news update

This episode is shared from Mayo Clinic Q&A and was recorded in May 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The widespread availability of at-home COVID-19 tests have made it easier for people to know if they have the virus, and to take measures to protect themselves and others. But there is a downside. Because the majority of tests are now done at home and often not reported, the official counts on COVID-19 infection rates are not as accurate as they have been in past waves of the virus.  "Because the majority of testing is being done at home, we can no longer tell you accurately about the positivity rate for a given community for a given state like we used to be able to," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "And this is problematic. It means that we lose our ability to understand what's called genetic epidemiology — the ability to trace how these variants are moving, how fast they're moving, and whether they're changing and evolving into yet different subvariants or new variants. We've lost that ability now." The most recent omicron subvariant, BA 2.12.1, has cases on the rise again and the U.S. passed a tragic milestone last week, reaching 1 million COVID-19 deaths in the country. In an effort to capture a more accurate picture, the latest tool being used by public health officials to track COVID-19 infection rates is wastewater surveillance. By looking for the presence of the COVID-19 virus shed by people, wastewater surveillance can give a more accurate picture of how much virus is in the community. This detects virus not only from those who test at home, but also from people who are asymptomatic and, therefore, didn't get tested. On the Mayo Clinic Q&A podcast, Dr. Poland discusses the current state of COVID-19 in the U.S., including what we know about the latest subvariants.
May 19, 2022
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Evaluating Adrenal Incidentalomas

Guest: Irina Bancos, M.D. (@IrinaBancos) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The widespread use of CT and MRI scans has resulted in frequent serendipitous findings, including adrenal nodules. When these nodules are found, two questions need to be answered. Is the nodule malignant and is this nodule metabolically active? This podcast will address these incidentally found adrenal nodules, also known as adrenal incidentalomas. We’ll review when these nodules should be investigated, the likelihood they represent a malignancy and how to assess if they’re metabolically active. Our guest for this podcast is Irina Bancos, M.D., an endocrinologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 17, 2022
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Eating Disorders Edition: Adult Eating Disorders

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest(s):   Scott Crow, M.D.; Carol B. Peterson, Ph.D., L.P. Host:  Jocelyn R. Lebow, Ph.D., L.P. While eating disorders are often thought of as disorders of adolescence, they impact adult patients across their lifespan. While many of the characteristics of these disorders are similar for pediatric vs. adult patients, there are important differences in how a primary care provider should assess and treat these illnesses in adults. As with younger patients, most adults report presenting initially to their primary care provider with their eating concerns, and many never seek additional care. This episode focuses on best practices for primary care providers in assessing and treating adult patients with eating disorders. Our guests are Scott Crow, M.D., Adjunct Professor of Psychiatry at the University of Minnesota and Vice President of Psychiatry at Accanto Health, and Carol B. Peterson, Ph.D., L.P., Clinical Psychologist and Professor in the Department of Psychiatry and Behavioral Sciences at the University of Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 12, 2022
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The Role of Monoclonal Antibodies in the Treatment of COVID-19

Guest: Raymund R. Razonable, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Monoclonal antibodies are laboratory-synthesized and mimic our immune system in fighting harmful pathogens. In addition to convalescent plasma and anti-viral medication, monoclonal antibodies have played an important role in the treatment of infections due to COVID-19. The use of monoclonal antibodies has been shown to shorten the duration of symptoms as well as reduce the risk of hospitalization and mortality due to COVID-19. This podcast will focus on monoclonal antibodies and our guest is Raymund R. Razonable, M.D., from the Division of Infectious Disease at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. Resource: O’Horo J, Challener DW, Anderson RJ, Arndt RF, Ausman SE, Hall ST, Heyliger A, Kennedy BD, Sweeten PW, Ganesh R, Razonable RR, Rates of Severe Outcomes After Bamlanivimab-Etesevimab and Casirivimab-Imdevimab Treatment of High-Risk Patients With Mild to Moderate Coronavirus Disease-2019, Mayo Clinic Proceedings (2022), doi: https://doi.org/10.1016/j.mayocp.2022.02.009.
May 10, 2022
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Mayo Clinic Q&A: COVID-19 news update

This episode is shared from Mayo Clinic Q&A and was recorded in April 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) An estimated 3 out of 4 U.S. children and more than half of all adults have been infected with COVID-19, according to a report released on Tuesday, April 26 by the Centers for Disease Control and Prevention. But a Mayo Clinic expert says more information is needed to get the complete picture. "This was a convenient sample. In other words, people who were having blood drawn for other reasons were tested,"explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "That does not reflect the full population or differences by race or geographic location. And the detection of antibodies does not necessarily mean that you are protected from infection. So, there's a lot of nuance around understanding that headline." The research study looked at more than 200,000 blood samples and found that signs of past infection rose dramatically during the omicron surge between December 2021 and February. Other COVID-19 news this week includes a push to make treatments more available, the rising incidence of new omicron subvariants, and changes in mask recommendations. Dr. Poland cautions that COVID-19 is still present and encourages wearing a mask in crowded spaces, even when there isn't a requirement to do so. "If only one of us is wearing a mask and the other one isn't and is infected, you still have pretty high protection — but not the same level of protection as if both of us wearing one," says Dr. Poland. "So, it's it is not futile to be the only one wearing a mask. In fact, I think it sends a message." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news and answers listener questions.
May 6, 2022
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Eating Disorders Edition: Case Discussions

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guests:  Angela C. Mattke, M.D. (@DrAngelaMattke); Paige I. Partain, M.D. Host:  Jocelyn R. Lebow, Ph.D., L.P. Though the Diagnostic and Statistical Manual of Mental Disorders (DSM–5) is clear in classifying eating disorders, clinicians understand it is rare to be presented with a straightforward case. Patients present with comorbidities and family circumstances that muddy the clinical picture and the treatment plan. This case-based episode focuses on how primary care providers can treat children with eating disorders. This episode will examine complicated eating disorder cases, featuring guests Angela C. Mattke, M.D. and Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatricians, and colleagues and collaborators in the primary care child and adolescent eating disorder clinic at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 5, 2022
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Fragility Fractures

Guest: Ann E. Kearns, M.D., Ph.D.          Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) It is estimated that worldwide, one in three women, and one in five men over the age of 50 will experience osteoporosis fractures during their lifetimes. In this podcast, we discuss risk factors and management of fragility fractures and bone health with Ann E. Kearns, M.D., Ph.D., a Consultant Endocrinologist and Associate Professor within the Department of Medicine at Mayo Clinic in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 3, 2022
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Eating Disorders Edition: Basic Principles of Treatment for the Primary Care Provider

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guests:  Angela C. Mattke, M.D. (@DrAngelaMattke); Paige I. Partain, M.D. Host:  Jocelyn R. Lebow, Ph.D., L.P. We understand eating disorders are serious and evidence-based Family Based Treatment (FBT) is scarce but effective. This episode will discuss strategies informed by evidence based FBT principles that can be used by providers in primary care settings to address eating disorder symptoms. Though typically the responsibilities of primary care providers in eating disorder treatment are limited to case identification, referral, and medical management, these providers have vast experience empowering caregivers to help their children change behavior.  Equipping primary care providers to deliver evidence-based treatment for restrictive eating disorders has the potential to expand access to early intervention and improve outcomes. Our guests for this episode are Angela C. Mattke, M.D. and Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatricians, and colleagues and collaborators in the primary care child and adolescent eating disorder clinic at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
April 28, 2022
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The Use of Race in Clinical Algorithms

Guest: Ramla N. Kasozi, M.B., Ch.B., M.P.H. Host: Darryl S. Chutka, M.D. (@ChutkaMD) There is currently a debate regarding the use of race and ethnic categories in clinical decision-making. There are numerous studies which claim data from race is a factor and should be considered when designing practice guidelines and clinical algorithms. Some feel that any benefit is small compared to the potential harm that could occur regarding the past abuse of race used in medicine. Unfortunately, many questions remain unanswered. Is race a reliable proxy for genetic differences? Are there genetic differences which explain the basis behind race-based algorithms? And what are the potential dangers of using race-adjusted algorithms? This podcast reviews these topics with Ramla N. Kasozi, M.B., Ch.B., M.P.H., a family physician at the Mayo Clinic in Jacksonville, Florida. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 26, 2022
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Eating Disorders Edition: Treatment for Eating Disorders

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest(s):  Jocelyn R. Lebow, Ph.D., L.P. Host:  Angela C. Mattke, M.D. (@DrAngelaMattke) Eating disorders impact an estimated 3-15% of adolescents and, if left untreated, or only partially treated, can become chronic conditions. Relapse is also common in eating disorders with over 40% of patients reporting at least one relapse in some studies. Despite these sobering statistics, when adolescent patients complete a course of good, evidence-based treatment, they can expect to make and maintain a full recovery from their symptoms. Primary care providers play a critical role in helping patients and their families find care and determine whether the care they’re getting is having the right effect. This episode will concentrate on different types of eating disorder treatment: what’s out there and what the evidence says works best. Our guest is Jocelyn R. Lebow, Ph.D., L.P., a Mayo Clinic child and adolescent psychologist and collaborator in the Mayo Clinic primary care child and adolescent eating disorder clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 21, 2022
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Secondary Hypertension: Identifying Clues in Patients

Guest: Sandra J. Taler, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD)  Nearly half of all adults in the United States have some degree of hypertension and it’s one of the most common reasons patients are seen in an outpatient practice. The vast majority have essential or primary hypertension and they usually respond to a combination of lifestyle changes and often pharmacologic therapy. A small percentage of these cases have secondary hypertension and often do not respond to treatment unless the underlying cause is found and corrected. At times, it can be difficult to identify the cause of secondary hypertension as the clues may be quite subtle or even non-existent. Our guest for today’s podcast is Sandra J. Taler, M.D. from the Division of Nephrology and a hypertension specialist from the Mayo Clinic. We’ll discuss when you should suspect secondary hypertension, the clues the patient may give us regarding its cause and its management. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 19, 2022
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Eating Disorders Edition: Medical Management of Eating Disorders in Primary Care

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guests:  Marcie L. Billings, M.D.; Paige I. Partain, M.D. Host:  Angela C. Mattke, M.D. (@DrAngelaMattke) The medical evaluation for eating disorders is very important. It is the primary care provider’s role to rule out other causes of weight loss, especially when eating disorder signs might not be as apparent at the beginning or the patient isn’t entirely forthcoming. Additionally, the patient and their family have an inherent trust in a primary care provider as their long-term medical provider. This episode will focus on the medical evaluation and management of eating disorders – what vital signs are significant, what labs are necessary including how often they should be performed, how frequently patients need to be seen in collaboration with their therapist, and how to determine if a patient is medically unstable and needing immediate admission for monitoring and treatment. The guests for this episode are Marcie L. Billings, M.D. and Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatricians, and colleagues and collaborators in the primary care child and adolescent eating disorder clinic at Mayo Clinic.  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 14, 2022
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Treating Hypertension: Doing What’s Best for Your Patient

Guest: Ivan E. Porter, II M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Nearly half of all adults in the United States have hypertension and it’s one of the most common reasons for an outpatient visit. Despite this, it’s estimated that only about a fourth of those diagnosed with hypertension are adequately controlled and about 20% of adults with hypertension are unaware that they even have it. Since uncontrolled hypertension can increase the risk of cerebral, cardiac and renal events, it’s important to make an accurate diagnosis and appropriately manage patients with the condition. The topic for this podcast is hypertension and we’ll discuss the changes in blood pressure with aging, the definition of hypertension, the proper technique of checking blood pressure and helpful management techniques with today’s guest, Ivan E. Porter, II M.D., a nephrologist and hypertension specialist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 12, 2022
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Eating Disorders Edition: Identification and Assessment of Eating Disorders for the Primary Care Provider

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest:  Paige I. Partain, M.D. Host:  Jocelyn R. Lebow, Ph.D., L.P. Child and adolescent eating disorders are serious diseases, characterized by a range of physical and psychological consequences. They are often associated with a chronic course and numerous relapses. This episode focuses on how primary care providers can assess for and identify eating disorders in child and adolescent patients. We will discuss high yield assessment questions and tools that you can use in your primary care practice when you suspect a young patient may meet the criteria for an eating disorder. Our guest is Paige I. Partain, M.D., Mayo Clinic Children’s Center pediatrician and collaborator in the primary care child and adolescent eating disorder clinic at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 7, 2022
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Eating Disorders Edition: Eating Disorders 101: Background and Debunking Myths

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest:  Jocelyn R. Lebow, Ph.D., L.P. Host:  Angela C. Mattke, M.D. (@DrAngelaMattke) Eating disorders are a huge problem in our country. Whether realizing it or not, primary care providers who treat teenagers are likely caring for patients with eating disorders.  Though estimates vary, approximately 3-15% of adolescents will experience an eating disorder. Along with the numerous physical and psychological consequences of these illnesses, eating disorders also have the second-highest mortality rate of any mental illness: one in five patients will die from complications related to their eating disorder.  This episode is the first episode in our Eating Disorders edition, which focuses on how primary care providers may treat children with eating disorders. This episode will concentrate on the basics: what are eating disorders, what do they do to our patients, and what myths and misunderstandings exist that hinder effective identification and treatment. Our guest is Jocelyn R. Lebow, Ph.D., L.P., a Mayo Clinic child and adolescent psychologist, and collaborator in the Mayo Clinic primary care child and adolescent eating disorder clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 5, 2022
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Mayo Clinic Q&A: COVID-19 metrics improve, expert still urges caution

This episode is shared from Mayo Clinic Q&A and was recorded in March 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Hospitalizations and deaths due to COVID-19 continue to decline, leading to some optimism about the way forward from pandemic to endemic. But experts still urge caution as the omicron subvariant, named BA.2, has quickly become the dominant strain in the U.S. "When you look around the nation, all of the metrics, with the exception of BA.2, have fallen precipitously," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "But we need to be very cautious about pretending that the pandemic is over." Dr. Poland explains that each time there has been a waning number of COVID-19 infections, people have let down their guard and relaxed precautions, which has led to another surge. Dr. Poland still recommends masking in crowded indoor settings and urges people to be fully vaccinated and boosted against COVID-19 to reduce the chance of infection. "We're just coming down into a quiet period," says Dr. Poland. "But every time we've seen this set of markers in the past, we've had a new variant that's caused a surge. The question is, will it be BA.2, one of the newer variants that have been identified, or something completely unexpected? We just don't know." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news including potential changes to booster recommendations, data on vaccine protection for pregnant women, and the latest information on COVID-19 vaccines for children under 5.  
March 31, 2022
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Colorectal Cancer – Screening Guidelines Updates

Guest: John B. Kisiel, M.D. (@DrJohnKisiel) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Colorectal cancer is the third most commonly occurring cancer for both men and women and ranks second to lung cancer as a cause of cancer mortality. Yet it’s estimated that up to one quarter of eligible adults in the United States have never been screened for colorectal cancer and nearly one third are not up to date with their screening. We now have a variety of accepted screening tests for colorectal cancer and each carries its own risks and benefits. This podcast will review colorectal cancer screening, including when we should start screening, the various available screening tests, as well as their advantages and limitations. Our guest for this episode is gastroenterologist, Dr. John Kisiel from the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 29, 2022
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Post COVID Syndrome

Guest: Greg Vanichkachorn, M.D., M.P.H. (@DoctorGregVan) Host: Darryl S. Chutka, M.D. (@ChutkaMD) While most patients who have COVID-19 completely recover within a few weeks, there are some patients who continue to experience symptoms that can last for months. These patients may require our care for an extended period of time.  Although much has been learned about COVID-19 over the past couple of years, there is still a great deal that’s not known. The topic for this podcast is post-COVID syndrome and our guest is Greg Vanichkachorn, M.D., M.P.H., a preventive medicine physician and specialist in Public Health. We’ll discuss the typical symptoms, duration of symptoms, and who is most likely to develop post-COVID syndrome. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 22, 2022
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Mayo Clinic Q&A: COVID-19 Update

This episode is shared from Mayo Clinic Q&A and was recorded in March 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Last week marked two years since the World Health Organization declared COVID-19 to be a pandemic. While infection rates and hospitalizations in the U.S. continue to decline, there are some areas of concern globally. "China, Hong Kong, Ireland, the U.K. and Denmark are seeing surges back up again," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "These countries, many of us experts believe, prematurely dropped mask-wearing and nonpharmaceutical interventions, and really have stopped pushing and encouraging people to get vaccinated. I think that's a mistake." Dr. Poland explains that public health measures — and vaccination and boosters — are still the best way to protect yourself from COVID-19. "What can I say but what we have said all along," implores Dr. Poland. "Hands, face, space and vaccines. It works." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news, including a study on the true death toll of COVID-19, an update on the BA.2 variant and the latest on vaccines for children under 5.
March 17, 2022
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Skin Cancer and Skin Lesions: What to Look For

Guest: Dawn Marie R. Davis, M.D. Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) Did you know that skin cancer is the number one cancer in the United States, with an estimated 3.5 million cases a year? In fact, your lifetime incidence is 1 in 5, or 20%. In this week’s podcast, Dawn Marie R. Davis, M.D., a Pediatric and Adult Dermatologist at Mayo Clinic in Rochester, Minnesota, discusses all things skin cancer. She provides tips and tricks in the management of common forms of skin cancer that providers need to be aware of when patients present with skin lesions. Dr. Davis also discusses the role of skin-protecting creams and their applicability to persons of all skin colors. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
March 15, 2022
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Mild Cognitive Impairment, Dementia, and Alzheimer’s Disease

Guest: Ronald C. Petersen, M.D., Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Nearly six million people in the United States age 65 and older have Alzheimer’s Disease; of these about 80% are 75 years old and older. It is a devastating disease, not only for the patient, but also for the family of the patient involved. Unfortunately, currently available treatment for Alzheimer’s has been disappointing. Cure or even stability of the cognitive loss is not possible. The topics for today’s podcast include mild cognitive impairment and dementia, focusing on Alzheimer’s Disease, and our guest is Ronald C. Petersen, M.D., a Mayo Clinic neurologist and specialist in Alzheimer’s Disease and other dementias. We’ll discuss the evaluation, the current available treatment as well as what might be on the horizon in the management of this disease. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 8, 2022
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Heart Disease in Women

Guest: Sharonne N. Hayes, M.D. (@SharonneHayes) Host: Darryl S. Chutka, M.D. (@ChutkaMD)   Cardiovascular disease remains the leading cause of death for individuals in the United States. Many assume this is primarily a disease of men, but it also continues to be the leading cause of mortality in women, accounting for one of every three female deaths. There’s also evidence that symptoms of cardiovascular disease may be somewhat different than in males. As a result, women are often given a different evaluation and may receive different treatment than males. To help us sort this out, our guest for this podcast is Sharonne N. Hayes, M.D., a cardiologist and specialist in women’s heart disease from the Mayo Clinic. We’ll discuss the misconceptions of cardiovascular disease in women, the variety of symptoms they may develop and treatment considerations that may be different than men typically receive. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
March 1, 2022
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Amyloidosis: Recognition, Diagnosis and Treatment

Guest: Eli Muchtar, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Amyloidosis is an uncommon disease, possibly even considered rare. It has a variety of presentations and some varieties tend to occur in association with other diseases. The presenting symptoms depend on the organ system involved. Unless we think of the condition, we may miss the opportunity to diagnose it early. As a result, many patients are diagnosed with amyloidosis at a rather advanced stage. The topic for this podcast is amyloidosis and our guest is Eli Muchtar, M.D., from the Division of Hematology at the Mayo Clinic. We’ll discuss the common organ systems affected by amyloidosis, how it’s diagnosed, the available treatment and the research currently taking place in amyloidosis. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 22, 2022
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Mayo Clinic Q&A: COVID-19 News Update

This episode is shared from Mayo Clinic Q&A and was recorded in February 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) As the U.S. moves beyond the omicron surge of the COVID-19 pandemic, key indicators are dropping. "Both the acute indicators — number of cases — and the lagging indicators — hospitalizations and then deaths — are all dropping slowly, but they're surely dropping," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.  Experts warn that caution is still needed to protect yourself in certain situations, including masking in crowded indoor settings and making sure you are up to date with your COVID-19 vaccinations and boosters. While the latest surge wanes, COVID-19 research continues.  On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news, including a new study on the long-term effects of COVID-19 on the heart and why Pfizer is delaying the request for emergency use authorization of its COVID-19 vaccine for children under 5.
February 17, 2022
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Infertility in Males

Guest: Sevann Helo, M.D. (@Helo_MD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Approximately one in seven couples is considered infertile. In a significant number of these couples, male infertility plays a role. Many of these couples will initially present to their primary care provider for help. Depending on our practice, we may not see all that many patients with this concern and, as a result, we might not be comfortable with the evaluation of the infertile couple. Today’s podcast will review infertility in males and hopefully give us a better understanding of the causes of infertility and how to evaluate the infertile male. Our guest for today’s podcast is Sevann Helo, M.D., a urologist at the Mayo Clinic. We’ll discuss what it takes for fertilization to take place, risk factors for infertility in males, the evaluation of the male for infertility, potential treatment options and effectiveness of treatment. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 15, 2022
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Dental Infections in the Primary Care Setting

Guest: Olivia (Liv) M. Muller, D.D.S. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Dental caries and periodontal disease are commonly seen by primary care providers in the outpatient setting. In fact, dental caries is the most common disease in the United States, both in children and adults. Up to 50% of children have dental caries, and most adults have at least one tooth with decay or have a filling. Gingivitis is also quite common in adults; it is present in up to half of all individuals between the ages of 35 and 45. Yet, unless we go into dentistry, healthcare providers don’t get much training in the evaluation of dental conditions. The topic of discussion for this podcast is dental care and dental infections. Our guest is Olivia (Liv) M. Muller, D.D.S., an Assistant Professor of Dentistry at the Mayo Clinic. We’ll discuss which dental problems we’re likely to encounter in our patients, recommendations we can give them to prevent dental infections and some of the more common complications of dental infections. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 8, 2022
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Mayo Clinic Q&A: Omicron wave wanes, new variant arises

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The number of new COVID-19 cases in the U.S. is dropping as the omicron wave wanes in many places, but some parts of the country lag behind. "As a nation, it looks like we've kind of gotten to the peak and are now starting on the decline, but it's very uneven," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "That's what's happening in the big Northeast cities, and maybe in L.A., for example. But if you look at the rest of the nation, it's not clear that they have peaked yet." And on the heels of the latest surge, a new omicron subvariant — BA.2 — is emerging. Early indications are that the new subvariant may be more transmissible, but it does not appear to cause more severe disease than the original omicron strain. Mayo experts, including Dr. Poland, continue to urge COVID-19 vaccinations and boosters as the best defense against the latest variants.  "By getting two doses of vaccine and a booster, or a dose of Johnson & Johnson and a booster, you move yourself into a category of maximal protection such that if you have a normal immune system, you are probably going to have trivial or even asymptomatic disease if you get infected with COVID-19," explains Dr. Poland.  On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest information on COVID-19 and answers listener questions.
February 3, 2022
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Shining a Light on Seasonal Affective Disorder

Guest: Craig N. Sawchuk, Ph.D., L.P. Host: Darryl S. Chutka, M.D. (@ChutkaMD) It is quite common for individuals to go through periods where they feel somewhat sad and discouraged and often these mood changes tend to occur with the changes in seasons, especially during the winter months. In some cases, these mood changes become more serious and can result in depression. When people experience depressive episodes in the late fall and winter, this may represent Seasonal Affective Disorder. Our guest today is Craig N. Sawchuk, Ph.D., L.P., a psychologist in the Department of Psychiatry & Psychology at the Mayo Clinic. Our topic for this podcast is Seasonal Affective Disorder. We’ll discuss its frequency, how we can recognize it in our patients, and the available treatment options. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 1, 2022
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Mayo Clinic Q&A: COVID-19 testing scenarios — what test and when?

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Matthew J. Binnicker, Ph.D. (@DrMattBinnicker) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Testing for COVID-19 is a part of the strategy to end the pandemic. But understanding testing — different types of tests and how and when to use them — can be confusing. Lab-run polymerase chain reaction, or PCR, tests and at-home antigen tests each have a role. "PCR tests are really sensitive, meaning we can detect really low levels of the virus in a sample," explains Dr. Matthew Binnicker, director of Clinical Virology at Mayo Clinic. "They're very specific, meaning we shouldn't get many false positive results with PCR tests." At-home antigen tests use a nasal swab and can produce results in 15 minutes, but they also have an increased chance of false-negative results, depending on when you test.  "At-home rapid antigen tests look for a viral protein in the patient sample," says Dr. Binnicker. "So they're quick and easy, but they also have some important limitations." So if you're worried you might have COVID-19, what test should you take and when?  On the Q&A podcast, Dr. Binnicker walks through various scenarios and makes testing recommendations for what to do if: You think you’ve been exposed but I don’t have symptoms. You have symptoms of COVID-19. You had COVID-19 and want to know if you're “in the clear” to return to work, school or activities.
January 27, 2022
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Chiropractic Care for Back Pain

Guest: Benjamin (Ben) D. Holmes, D.C., Ph.D. Host: Edward R. Laskowski, M.D. (@DrEdSportsMed) Low back pain is one of the most common conditions that physicians see in their practices. Studies indicate that, by the age of 50 years old, approximately 80% of people will experience low back pain in their lives. Joining us today is Benjamin D. Holmes, D.C., Ph.D. a practicing chiropractor and one of the spine specialists in the Mayo Clinic Spine Center. Dr. Holmes will discuss various treatment interventions for back pain, as well as misconceptions and assumptions regarding chiropractic treatment. Additional Resources: Foster, N. E., Anema, J. R., Cherkin, D., Chou, R., Cohen, S. P., Gross, D. P., ... & Woolf, A. (2018). Prevention and treatment of low back pain: evidence, challenges, and promising directions. The Lancet, 391(10137), 2368-2383. Bialosky, J. E., George, S. Z., Horn, M. E., Price, D. D., Staud, R., & Robinson, M. E. (2014). Spinal manipulative therapy–specific changes in pain sensitivity in individuals with low back pain (NCT01168999). The Journal of Pain, 15(2), 136-148. Cook, C., Learman, K., Showalter, C., Kabbaz, V., & O'Halloran, B. (2013). Early use of thrust manipulation versus non-thrust manipulation: a randomized clinical trial. Manual Therapy, 18(3), 191-198. Chou, R., Fu, R., Carrino, J. A., & Deyo, R. A. (2009). Imaging strategies for low-back pain: systematic review and meta-analysis. The Lancet, 373(9662), 463-472. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 25, 2022
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Mayo Clinic Q&A: Why getting infected with COVID-19 is still a bad idea

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) With the highly transmissible omicron variant spread across the U.S., it may seem inevitable that most people will get infected with COVID-19. But Mayo Clinic experts explain why it is important to continue to be vigilant and take measures to avoid COVID-19 infection.  "One of the many negatives about saying, 'Well, I'll just go ahead and get infected and get it over with' is you can spread the virus to highly vulnerable people," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "Parents, grandparents, people too young to be immunized, and people whose immune systems might not be working well are all at risk of more severe disease. While your case may be mild, theirs may not."  Dr. Poland cautions that the sheer number of infections is stressing the health care system, and treatments for omicron are more limited than they were for the delta variant. "The role of testing and of getting boosted is critical to our response to this, and remember, even though you might have mild disease, every time this virus infects somebody, it is the opportunity for further mutation." says Dr. Poland.  Vaccination, boosting and masking are all necessary to prevent the spread of omicron. "Your best chance of protecting yourself is to be fully vaccinated, wear a proper mask properly when in public, and to avoid crowded indoor settings," says Dr. Poland. On the Mayo Clinic Q&A podcast, Dr. Poland discusses the omicron surge and answers listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 20, 2022
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Improving Medication Adherence

Guest: Kristina M. Thurber, Pharm.D., R.Ph. Host: Darryl S. Chutka, M.D. (@ChutkaMD) There are a variety of outstanding pharmaceutical products we use to treat the multiple health problems our patients develop and every year, clinical research has provided us with new and improved therapeutic options. When we prescribe a medication to a patient, we generally assume they’ll take it exactly as prescribed. Unfortunately, that’s not necessarily true. Non-adherence to chronic medications is surprisingly common and can account for up to half of all treatment failures. Our guest for this podcast is Kristina M. Thurber, Pharm.D., R.Ph., a medication therapy pharmacist at the Mayo Clinic. We’ll discuss the prevalence of medication adherence, its causes, how we can recognize it in our patients and management strategies to improve adherence. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 18, 2022
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All Age-Related Changes May Not Be Inevitable: Senescent Cells and Anti-Aging

Guest: Nathan K. LeBrasseur, Ph.D., M.S. (@NKLeBRASSEUR) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The effects of aging occur in all our organs. In muscles, there is a reduction in strength and stamina; the brain shows a decrease in cognitive function and the ability to learn new information. Aging causes a reduced ability of the liver to metabolize drugs and the kidney’s ability to eliminate various waste products. Our guest for this podcast is aging researcher Nathan K. LeBrasseur, Ph.D., M.S., the senior author of a study recently published in the journal “Aging Cell.” The authors described significant benefits from exercise on a cellular level which correlated with an improvement in physical changes related to aging. We’ll discuss cellular changes which occur with aging, the significance of senescent cells and how exercise can reduce the impact of aging on both a cellular level as well as clinically. Specific topics: The effects of aging on a cellular level Variability in the rate of aging in individuals Function of senescent cells Effects of exercise on senescent cells Clinical correlations resulting from the elimination of senescent cells Recommendations clinicians can give their patients to reduce the effects of aging
January 11, 2022
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Mayo Clinic Q&A: January Bringing an Omicron Surge

This episode is shared from Mayo Clinic Q&A and was recorded in January 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The rapid spread of COVID-19 due to the omicron variant continues, and experts expect a January surge across the U.S.  "This is spreading unlike anything we've seen in the U.S.," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.  "Over the last seven days, we're now averaging about 400,000 or so new cases a day." While people who are fully vaccinated can get breakthrough infections and spread the virus to others, COVID-19 vaccines effectively prevent severe illness. Mayo Clinic experts urge people to protect themselves by getting vaccinated and wearing a mask. Being fully vaccinated, including getting a booster when eligible, offers the highest protection possible against COVID-19.  "The good news is, for those who are immunized and boosted, we are winning the battle," says Dr. Poland. "Getting immunized is basically a weapon against this virus." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the omicron surge and the importance of vaccines and boosters for COVID-19. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 6, 2022
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Temporal Arteritis

Guest: Andy Abril, M.D. (@andyabrilMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Temporal arteritis is a vasculitis involving medium-sized vessels and typically occurs in those over the age of 50. If diagnosed and treated early, there is an excellent likelihood of recovery. However, temporal arteritis often mimics other health problems and this commonly results in a delay in the diagnosis. If untreated, serious complications can occur, including permanent blindness or stroke. The topic for this podcast is temporal arteritis and our guest is Andy Abril, M.D., Chair of the Division of Rheumatology at the Mayo Clinic in Jacksonville, Florida. We’ll discuss the risk factors, presenting symptoms and complications of temporal arteritis, as well as the recommendations for establishing a diagnosis and initiating appropriate treatment. Specific topics discussed: Risk factors for temporal arteritis Presenting symptoms Complications of untreated temporal arteritis Extra-cranial artery involvement of patients with temporal arteritis Relationship of temporal arteritis and polymyalgia rheumatica Laboratory abnormalities in temporal arteritis Importance of an early temporal artery biopsy in establishing a diagnosis Treatment recommendations Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 4, 2022
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Nutritional Supplement Edition: Research and Regulation

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, PhD Host: Darryl S. Chutka, M.D. (@ChutkaMD) How can we tell if the claims made by nutritional supplement companies are factual?  In this episode we'll discuss the research currently being done in this field and whether the research findings are valid.  Finally, we’ll talk about regulation of nutritional supplements. Our guest for this podcast is Andrew R. Jagim, Ph.D., the director of Sports Medicine research at the Mayo Clinic. Specific topics: Importance of a foundation of good nutrition and exercise related to the benefits of nutritional supplements Amount and quality of research being done on nutritional supplements Regulation of nutritional supplements How healthcare providers and consumers can judge the many claims made by manufactures of nutritional supplements
December 30, 2021
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Lung Cancer Screening

Guest: Sebastian Fernandez-Bussy, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Lung cancer is the second most common malignancy in both men and women.  Survival rates depend on how early the cancer is discovered, with a survival rate much higher in localized disease than for patients with distant metastases. Therefore, an early diagnosis becomes extremely important. One of the problems with early diagnosis is that until recently, we’ve not had an effective screening test for lung cancer. In this podcast, we’ll be speaking with Sebastian Fernandez-Bussy, M.D., an Interventional Pulmonologist from the Division of Pulmonary and Critical Care at the Mayo Clinic in Jacksonville, Florida, and we’ll discuss proven techniques for lung cancer screening. Specific topics: Benefits in survival in finding lung cancer at an early stage Candidates for screening patients at an increased risk for lung cancer Evidence showing the benefits of lung cancer screening Differences in radiation for chest CT scans used for screening vs. a typical diagnostic chest CT scan Frequency of indeterminate pulmonary nodules found on chest CT Insurance and Medicare coverage for lung cancer screening Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 28, 2021
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Nutritional Supplements Edition: Family Medicine Case Studies

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guests: Andrew R. Jagim, Ph.D. Jakob R. Erickson, D.O. Host: Darryl S. Chutka, M.D. (@ChutkaMD) The care of athletes often requires special knowledge that many healthcare providers are less familiar with.  Athletes may have somewhat unique health problems related to their endurance or strength training.  They may also be taking a variety of nutritional supplements which could cause health issues.  This case-based podcast covers a couple different examples of health issues experienced by athletes. Featured guests include Andrew R. Jagim, Ph.D. and Jacob R. Erickson, D.O. from Sports Medicine at Mayo Clinic. We’ll discuss some of the medical issues often faced by athletes. Specific topics: Iron-deficiency anemia Relative Energy Deficiency in Sport Vitamin D deficiency and hypervitaminosis D Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 23, 2021
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Infertility in Females

Guest: Elizabeth A. Stewart, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Infertility can be related to health issues in the male, female or both. Whatever the reason, infertility can put a major strain on a couple’s relationship. To add to the stress, infertility often results in multiple exams, tests, injections and procedures for one or both of the couple. Fortunately, the cause of infertility can often be found and in some cases, treatment is effective, resulting in a successful pregnancy and birth. The topic of discussion for this podcast is infertility, specifically infertility in females. Our guest is Dr. Elizabeth (Ebbie) A. Stewart, a physician in the Department of Obstetrics and Gynecology and Division of Endocrinology and Infertility. We’ll review the prevalence of infertility in females, males and both, risk factors for infertility, the most common causes of infertility and the evaluation a primary care provider can perform. Specific topics discussed: Definition of infertility Prevalence of infertility Risk factors for infertility Recommended evaluation by primary care providers Specialized evaluation performed by an infertility expert Common causes of infertility in females Success of infertility treatment Invitro fertilization as a treatment alternative to infertility including cost, success rate and risk of multiple births Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 21, 2021
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Mayo Clinic Q&A: Experts urge COVID-19 boosters to fight omicron surge

This episode is shared from Mayo Clinic Q&A and was recorded in December 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) More Americans are now eligible for COVID-19 booster doses as the Centers for Disease Control and Prevention approved the Pfizer vaccine booster for 16- and 17-year-olds late last week. Previously, only those 18 and older were eligible. Early research suggests that a booster dose of the Pfizer COVID-19 vaccine improves protection against severe disease caused by the omicron variant, according to Pfizer. Mayo Clinic experts say, regardless of the variant, prevention of infection works. Getting a booster offers the highest protection possible against COVID-19. "Omicron infection rates are picking up rapidly," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "If we do not take the proper precaution over the holiday, we are going to see a January omicron surge." Dr. Poland explains that there are two threats — delta and omicron COVID-19 variants — but there is a solution. "Masking and boosting — those are key to protecting yourself and your family." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest on COVID-19 variants and shares advice on how to stay safe this holiday season. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 17, 2021
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Nutritional Supplement Edition: Weight Loss and Thermogenic Agents

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Are there supplements available that really assist with weight loss? How can you help your patients navigate the market? What is safe and what do they need to look out for? Andrew R. Jagim, Ph.D., the director for Sports Medicine research at the Mayo Clinic, answers these questions in this episode.  We discuss the importance of diet and exercise in weight loss and the benefits nutritional supplements may add.  We also discuss some of the more common supplements promoted to enhance thermogenesis and weight loss as well as their proposed mechanism of action. Specific topics: Popular nutritional supplements for enhancing weight loss Accuracy of claims for nutritional supplements Importance of diet and exercise in producing significant weight loss Potential benefits of a nutritional supplement in addition to exercise and diet in producing significant weight loss Common supplements promoted to enhance weight loss
December 16, 2021
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Influenza Vaccine 2021

Guest: Robert M. Jacobson, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Preventing influenza is important for a variety of reasons. Influenza is not a benign illness. In recent years, it’s accounted for up to 700,000 hospitalizations and over 50,000 deaths annually. The vaccine not only saves lives but also helps prevent hospitalizations as well as the need for the ICU. The occupancy rates of both have been severely stressed due to COVID. Despite the fact that the vaccine has been shown to be effective in all age groups, a significant percent of the population do not receive it. This podcast will discuss the influenza vaccine, it’s overall effectiveness in preventing the illness, the optimal time of year to receive the vaccine and tips on how to increase the likelihood that our patients will agree to receive it. Our guest is Dr. Robert M. Jacobson, a pediatrician and immunization expert at the Mayo Clinic. Specific topics: Possible impact on the susceptibility or severity of influenza for the 2021/2022 season given there was such a reduction in influenza cases last year The time of year the vaccine for the current influenza season is released The optimal time of year to receive the influenza vaccine The effectiveness of the influenza vaccine in preventing the illness The likelihood we’ll see testing for both COVID and influenza increase this winter Tips on increasing the number of patients who agree to receive the influenza vaccine Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 14, 2021
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Mayo Clinic Q&A: Post COVID-19 syndrome can be a long haul

This episode is shared from Mayo Clinic Q&A and was recorded in December 2021 Guest:  Greg Vanichkachorn, M.D., M.P.H. (@DoctorGregVan) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Most people who have COVID-19 recover completely within a few weeks. But some people — even those who had mild versions of the disease — continue to experience symptoms after their initial recovery.  Sometimes called “long haulers” or “long COVID," these patients can have fatigue, shortness of breath, brain fog and other symptoms long after the time of their infection. Post-COVID-19 syndrome conditions are generally considered to be effects of COVID-19 that persist for more than four weeks after you've been diagnosed with COVID-19 infection. A recent Mayo Clinic study on post-COVID-19 symptoms found that more women than men suffer long-term effects. Women predominantly showed symptoms of fatigue, followed by muscle pain and low blood pressure, while men primarily experienced shortness of breath. Research is also underway to better understand what may be causing post-COVID-19 syndrome. "We do have some research now that shows that some of the cells that are used to create immunity after an infection, they may be malfunctioning in this condition in patients with long-haul COVID," says  Dr. Greg Vanichkachorn, director of Mayo Clinic’s COVID Activity Rehabilitation Program. "We also now have some research that shows that patients with this condition can have antibodies against themselves, otherwise known as an auto-antibody. And this may be associated with the long-haul COVID state, so immune dysfunction and auto immunity, they may be at play here." The COVID Activity Rehabilitation Program at Mayo Clinic helps people experiencing post-COVID-19 syndrome by working with patients to decrease symptoms and improve overall functioning and quality of life.  On the Mayo Clinic Q&A podcast, Dr. Vanichkachorn discusses how treatment can help patients who suffer from post-COVID-19 syndrome. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 10, 2021
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Nutritional Supplements Edition: Strength, Power, and Performance

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Nutritional supplements are being promoted to enhance a variety of areas of physical fitness. This episode focuses on the impact on strength, power and overall performance. Our guest for this podcast is Andrew R. Jagim, Ph.D., the director of Sports Medicine research at Mayo Clinic. Specific topics: Activities that benefit from increased strength and performance Lifestyle strategies used to enhance strength and performance Common nutritional supplements used to increase strength and performance Safety concerns regarding the use of nutritional supplements Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 9, 2021
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Recommendation for Your Arthritic Patients – Keep Them Moving

Guest: Edward R. Laskowski, M.D. (@DrEdSportsMed)  Host: Darryl S. Chutka, M.D. (@ChutkaMD) Arthritis is one of the most common health conditions our patients have for eliminating exercise from their daily routine, yet the American College of Rheumatology feels that exercise should be one of the mainstays of treatment for those with arthritis. How do we convince our patients of the importance of continued exercise despite their arthritis? Are some types of exercise better than others? Can exercise make their arthritis worse? We’ll discuss these questions with Dr. Edward R. Laskowski, a Sports Medicine physician from the Department of Physical Medicine and Rehabilitation at Mayo Clinic. Specific topics: Benefits of exercise in patients who have arthritis Exercises that patients with arthritis should avoid What patients should do if they have increased joint pain after exercising Joint-friendly exercises that can be done by most patients Importance of performing resistance as well as aerobic exercise Recommended frequency and duration of exercise Exercises for the was with inflammatory arthritis Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 7, 2021
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Nutritional Supplement Edition: Exercise Endurance and Recovery

Guest: Andrew R. Jagim, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Can nutritional supplements help to increase exercise endurance? What types of supplements can help with short term – immediate improvements and which can assist with longer term recovery? Andrew R. Jagim, Ph.D., director of Sports Medicine research at Mayo Clinic joins us to discuss some of the claims that we can hear about nutritional supplements promoted to prove one's endurance, increase exercise economy, and improve tolerance of high-intensity exercise. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 2, 2021
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Mayo Clinic Q&A: Boosters reduce vulnerability to COVID-19 variants

This episode is shared from Mayo Clinic Q&A and was recorded in November, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Omicron, a new COVID-19 variant of concern, has been detected in all regions of the world, including North America. While research and clinical observations on the new strain are underway, it is not yet known what impact, if any, omicron will have on the immune response, transmissibility, or specific COVID-19 treatments. The emergence of omicron is a reminder to take important steps to protect yourself against COVID-19. "The answer is masking and boosters," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.  Dr. Poland is encouraged by vaccine booster rates in the U.S. "In a relatively short period of time, about 36% of adults who are eligible have indeed gotten a booster," says Dr. Poland. "There's plenty of vaccine available. So in the strongest possible terms, I would recommend getting that booster." Adults who are six months past completing their initial Moderna or Pfizer COVID-19 vaccination series are eligible to receive a booster dose, as are adults who are two months past completing their initial dose of the Johnson & Johnson vaccine. On the Mayo Clinic Q&A podcast, Dr. Poland discusses the omicron variant and COVID-19 boosters, and he answers some listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
December 1, 2021
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Nutritional Supplement Edition: A Critical Overview

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Nutritional Supplement Edition Guest:  Andrew R. Jagim, PhD Host: Darryl S. Chutka, M.D. (@ChutkaMD) Imagine taking a supplement that increases muscle mass, improves strength and endurance, promotes weight loss, helps prevent injury from exercise and promotes healing. Do these supplements exist and are they safe? This episode discusses nutritional supplements. We will discuss proven benefits as well as risks. Our guest for this podcast is Andrew R. Jagim, Ph.D., the director of Sports Medicine research at Mayo Clinic. Specific topics: Definition of nutritional supplements Common reasons to take these products Accuracy of claims that nutritional supplements improve fitness and enhance performance Research conducted on nutritional supplements Regulation of the nutritional supplement industry Potential safety issues in taking nutritional supplements Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 30, 2021
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Racism in Pain Medicine

Guest: Natalie H. Strand, M.D. (@DrNatStrand) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Racial biases can influence diagnosis and treatment decisions. It is important to normalize implicit biases and be aware of our own biases to reduce disparities and improve health care for patients. Joining us today is Natalie Strand, M.D., a consultant in the Department of Anesthesiology and Perioperative Medicine at the Mayo Clinic Hospital in Phoenix, AZ. She will discuss the unique, relevant and timely topic of racism in pain medicine, including the occurrence of racism in medicine at all levels – from patient care, diagnoses and outcomes to professional development of physicians. She describes our responsibility and how, if we want to engage in anti-racism, we must do it at all levels in medicine. Additional Resources: Strand, N. H., Mariano, E. R., Goree, J. H., Narouze, S., Doshi, T. L., Freeman, J.A., Pearson, A. C. S. (2021). Racism in Pain Medicine: We Can and Should Do More. Mayo Clinic Proceedings, 96(6), 1394-1400. https://doi.org/10.1016/j.mayocp.2021.02.030 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 23, 2021
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Mayo Clinic Q&A: Travel trends and colder temperatures could mean a COVID-19 holiday surge

This episode is shared from Mayo Clinic Q&A and was recorded in November, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Cold weather, increased travel, waning immunity and the potential for new variants may serve up the perfect recipe for a holiday COVID-19 surge, according to Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group.   "I have consistently said what's very likely to happen as we get to the cooler weather and see the trends in travel is that we will have another surge," says Dr. Poland. "We're in this unusual situation where the pandemic is actually getting worse because humans don't want to believe that the pandemic is just as important now as it was a year ago." In this Mayo Clinic Q&A podcast, Dr. Poland answers several listener questions and talks more about being vigilant against COVID-19 as the U.S. heads into a second winter with this coronavirus. He also addresses the recent news that wild deer have shown evidence of COVID-19 infection and what that might mean in the battle to eliminate the disease.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 22, 2021
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Genes and Your Health Series: Hot Topics in Phage Therapy

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Gina A. Suh, M.D. Host: Denise M. Dupras, M.D., Ph.D. What is Phage Therapy? When was it discovered? Where is it used? We know about antibiotics, antifungals, and antivirals, but this is a whole new world! Have no fear, this episode is here from the Genes & Your Health miniseries to help demystify all there is to know about Phages. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
November 18, 2021
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Hyperlipidemia

Guest: Monique A. Freund, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Hyperlipidemia is one of the major risk factors for cardiovascular disease. It’s known that a combination of lifestyle changes and pharmacologic therapy has proven effective in reducing the complications of cardiovascular disease. Despite this, it’s estimated that less than 35% of those patients with hyperlipidemia are adequately managed. Why aren’t we doing a better job at managing this major public health problem? In this podcast, we’ll be speaking with Monique A. Freund, M.D., a cardiologist at Mayo Clinic. We’ll discuss how to optimize management of hyperlipidemia, which lifestyle changes are beneficial, when to use pharmacologic therapy and how to manage patients with statin intolerance. Specific topics: Relative importance of elevated LDLc, low HDLc and elevated triglycerides Effective non-pharmacologic therapy for treating elevated LDLc, low HDLc and elevated triglycerides When to consider starting a patient on a statin Benefits of fish oil Mechanism of action of statins Statin intolerance When to use ezetimibe When to use one of the PCSK9-inhibitors Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 16, 2021
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Genes and Your Health Series: Predicting the Future: What Role is Artificial Intelligence Playing Today and What Can We Expect in the Future?

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Christopher (Chris) A. Aakre (@ChrisAakreMD), M.D.; Bradley J. Erickson, M.D., Ph.D. Host: Denise M. Dupras, M.D., Ph.D. Artificial Intelligence has begun being utilized in Radiology. In fact, it was boldly predicted that Radiology would become an obsolete profession as a result! How has it altered this practice? How will it alter our practices moving forward? Join this episode of our Genes & Your Health miniseries from the Center of Individualized Medicine to learn these answers and more! Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 11, 2021
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The Eyes Have It: Common External Eye Conditions

Guest: Amir R. Khan, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) External eye disorders are commonly seen in a primary care provider’s office, yet very few of us have ever had any formal training in ophthalmology. Fortunately, most of the external eye problems are relatively benign, though not all. It’s important to be able to recognize these conditions since some may be associated with a variety of systemic diseases. In this podcast, Amir Khan, M.D., an ophthalmologist at Mayo Clinic, joins Dr. Chutka to discuss how to recognize commonly seen external eye conditions. Links to specific topics below include additional information and images for most of the covered conditions. Specific topics: Viral versus bacterial conjunctivitis: https://www.mayoclinic.org/diseases-conditions/pink-eye/symptoms-causes/syc-20376355 Scleritis and episcleritis Blepharitis: https://www.mayoclinic.org/diseases-conditions/blepharitis/symptoms-causes/syc-20370141 Sty (Hordeolum): https://www.mayoclinic.org/diseases-conditions/sty/symptoms-causes/syc-20378017 Ectropion versus entropion: https://www.mayoclinic.org/diseases-conditions/ectropion/symptoms-causes/syc-20351164; https://www.mayoclinic.org/diseases-conditions/entropion/symptoms-causes/syc-20351125 Subconjunctival hemorrhage: https://www.mayoclinic.org/diseases-conditions/subconjunctival-hemorrhage/symptoms-causes/syc-20353826 Herpes zoster ophthalmicus Corneal abrasions: https://www.mayoclinic.org/first-aid/first-aid-corneal-abrasion/basics/art-20056659 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 9, 2021
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Mayo Clinic Q&A: Building a wall of immunity against COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in November  3, 2021 Guest:  Elie F. Berbari, M.D. Host: Halena M. Gazelka, M.D. (@hmgazelkamd) In anticipation of more COVID-19 vaccine approvals this week, Dr. Elie Berbari, chair of the Division of Infectious Diseases at Mayo Clinic, says it's good news that younger children will now have more protection against COVID-19. "It's important that we reach a very high level of vaccination rates to achieve kind of a wall of immunity that could prevent transmission and prevent us from these repeated peaks that we've been dealing with over the last year and a half during this pandemic," says Dr. Berbari.  In this Mayo Clinic Q&A podcast, Dr. Berbari also talks about the rare cases of myocarditis and how the Food and Drug Administration is monitoring those cases. Dr. Berbari also addresses additional COVID-19 vaccine doses for immunocompromised people, the importance of masking, even if vaccinated, and he answers a number of listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 5, 2021
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Genes & Your Health Edition – Preparing Your Practice for the Increased Use of Genomics

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Megan A. Allyse, Ph.D. (@MAllyse); Jennifer (Jenny) L. Anderson, M.S., CGC; Radhika Dhamija, M.B.B.S. (@NeurogenesDr) Host: Denise M. Dupras, M.D., Ph.D. Genetic testing is increasingly becoming mainstream. Not only is it first-line testing for many different indications, but we have begun seeing an increase in predictive genomics for healthy patients as well. How can your practice prepare for what is here and what is to come? Tune in to this episode of the Genes & Your Health miniseries from the Center for Individualized Medicine to find out. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 4, 2021
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Developing Equitable Care Models for Diabetic Patients

Guest: Rozalina G. McCoy, M.D., M.S. (@RozalinaMD) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Diabetic research starts with understanding contemporary treatment practices (overtreatment and undertreatment, misuse or underuse of glucose-lowering medications, comparative effectiveness of different diabetes medications), the resulting impact on patient health and the disparities in both treatment practices and outcomes. In this episode Rozalina McCoy, M.D., M.S., associate professor of medicine and consultant in the Division of Community Internal Medicine at Mayo Clinic’s Rochester campus, joins us to discuss developing care delivery models that support high-quality, evidence-based, patient-centered, and equitable diabetes care. Additional resources: McCoy RG, Galindo RJ, Swarna KS, et al. Sociodemographic, clinical, and treatment-related factors associated with hyperglycemic crises among adults with type 1 or type 2 diabetes in the US from 2014 to 2020. JAMA Netw Open. 2021;4(9):e2123471. doi:1001/jamanetworkopen.2021.23471 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 2, 2021
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Genes & Your Health Edition – Genomics for Cardiovascular Health in Primary Care

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guest: Iftikhar J. Kullo, M.D. (@iftikhar_kullo) Host: Denise M. Dupras, M.D., Ph.D. What is familial hypercholesterolemia? Who should be tested for it? Are there genetic variants that are associated with cardiovascular diseases? How young do we start screening? This installment of the Genes & Your Health miniseries from the Center for Individualized Medicine is here to help answer these questions and more! Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 28, 2021
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Preserving Sight with Macular Degeneration

Guest: Sophie J. Bakri, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Macular degeneration is the most common cause of vision loss in individuals over the age of 50. The loss of central vision from macular degeneration can result in significant lifestyle changes in patients. They may no longer be able to read, write or drive. In this podcast, we’ll discuss macular degeneration with Sophie Bakri, M.D., an ophthalmologist at Mayo Clinic. She’ll review the two types and pathology of macular degeneration, its presentation, risk factors and preventive strategies, and new treatments on the horizon. Specific topics: Pathologic changes in macular degeneration Vision loss associated with macular degeneration Possible causes of macular degeneration Risk factors Typical course of macular degeneration The difference between wet and dry macular degeneration Treatment strategies Preventive strategies Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 26, 2021
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Mayo Clinic Q&A: Changing COVID-19 recommendations means the science is working

This episode is shared from Mayo Clinic Q&A and was recorded in October, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) As continuing research guides medical recommendations, it seems that there are COVID-19 updates released daily. These recommendations cover a range of topics, including whether COVID-19 booster vaccinations are necessary to whether COVID-19 vaccines can be mixed and matched. "The fact that recommendations are changing is not evidence people don't know what they're doing," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "It's evidence that they do know what they're doing and are paying close attention to new data that's coming along. Then they're adjusting recommendations based on the latest data." Dr. Poland continues to urge people to get the latest COVID-19 news from credible sources.  In this Mayo Clinic Q&A podcast, Dr. Poland walks through the recent recommendations, corrects misperceptions and answers a number of listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 22, 2021
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Genes & Your Health Edition – Cell-Free DNA: Implications in Practice

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Minetta C. Liu, M.D.; Myra J. Wick, M.D., Ph.D. (@MyraWickMD) Host: Denise M. Dupras, M.D., Ph.D. What is cell-free DNA? How does this type of DNA interact with our body? How is it useful in the clinical setting? Advances in technologies has expanded our understanding of cell-free DNA and its implications. Where are we now and what can we look for in the future? Find out these answers and more in the seventh episode of the Genes & Your Health miniseries from the Center for Individualized Medicine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 21, 2021
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A Neurologist’s Take on Syncope

Guest: Paola Sandroni, M.D., Ph.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Syncope is defined as the sudden and transient loss of consciousness and postural tone due to global reduction of blood flow to the reticular activating system. Syncopal episodes are followed by a rapid and spontaneous recovery.  Joining us today is Paola Sandroni, M.D., Ph.D., a neurologist at Mayo Clinic’s Rochester Campus. She will help us sort through the complicated subject of syncope, including its main etiologies and how to distinguish which is affecting your patient. She also outlines the nuances of evidence-based evaluation of syncope, which is largely guided by the patient’s presentation. Additional resources: Thiruganasambandamoorthy V, Kwong K, Wells GA, Sivilotti MLA, Mukarram M, Rowe BH, Lang E, Perry JJ, Sheldon R, Stiell IG, Taljaard M. Development of the Canadian Syncope Risk Score to predict serious adverse events after emergency department assessment of syncope. CMAJ. 2016 Sep 6;188(12):E289-E298. doi: 1503/cmaj.151469. Epub 2016 Jul 4. PMID: 27378464; PMCID: PMC5008955 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 19, 2021
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Genes & Your Health Edition – Why Does It Matter? Genes, Hormones, and Women’s Health

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Stephanie S. Faubion, M.D., M.B.A. (@StephFaubionMD); Kejal Kantarci, M.D. (@KejalKantarciMD); Juliana (Jewel) M. Kling, M.D., M.P.H. (@DrJewelKling) Host: Denise M. Dupras, M.D., Ph.D. Is hormone therapy good or bad for women? What are the myths surrounding it? Is the varying experience of menopause genetic? Join the sixth episode of Mayo Clinic Center for Individualized Medicine’s Genes & Your Health Edition to dive into women’s health and hormones and what you need to know for your practice.   Additional resources: • USPSTF Recommendations Statement for Breast Cancer: Medication Use to Reduce Risk https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction  • Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 14, 2021
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Using Artificial Intelligence to Combat COVID-19

Guest: Thomas Caulfield, Ph.D. Host: Amit K Ghosh, M.D., MBA (@AmitGhosh006) In this podcast, Dr. Thomas Caulfield from Mayo Clinic Florida describes a novel approach for SARS-CoV2 multi-drug targeting using artificial intelligence. Dr. Caulfield is leading a national team of investigators from Harvard, University of California, In Vivo Biosystems and Mayo Clinic to perform large-scale in silico and in vivo experiments on de novo drugs to better understand COVID-19 and halt its progression.  University of California hosts a live virus BSL3 facility for rapidly screening novel compounds that Dr. Caulfield's lab designs in silico and refines with feedback using machine learning techniques and data layering. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 12, 2021
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Genes & Your Health Edition – How Does Your Microbiome Impact Your Health?

To claim credit for this series, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guest: Purna C. Kashyap, M.B.B.S. (@KashyapPurna); Marina R. Walther-Antonio, Ph.D. Host: Denise M. Dupras, M.D., Ph.D. What is the microbiome? How does the microbiome interact with our body? How much of us is nurture, how much is nature? The whole concept of microbiome may be a new idea but have no fear this fifth episode of the Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine is here to help answer those questions and more! Additional resources: Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 7, 2021
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Mayo Clinic Q&A: Breaking Down COVID-19 Vaccine Booster Approvals

This episode is shared from Mayo Clinic Q&A and was recorded in September 29, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The path to approvals for a booster dose of the Pfizer COVID-19 vaccine has seemed complicated.  "This is a confusing set of recommendations," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "So let's look at the four groups approved for only the Pfizer booster, thus far. If you got a primary series of the Pfizer vaccine, you're 65 and older, and it's been six months or more, you are eligible for a booster. If you're 50–64 and you have medical conditions that place you at high risk, you are eligible for the booster. If you're 18–49, you may be able to get a booster based on a medical condition and if you talk with your health care provider to weigh risks and benefits. And, finally, for people 18–64 years old, who are health care providers in congregate living situations or who have occupations that place them at high risk for transmission, such as school teachers, they also may be eligible. That should happen very soon." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about the approval process for COVID-19 vaccine boosters, including for the Moderna and Johnson & Johnson COVID-19 vaccines. He also discusses the possibility that emergency use approval for children, down to age 5, could come before the end of October. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 6, 2021
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Breast Imaging for Patients with Dense Breast Tissue

Guest: Christina A. Dilaveri, M.D. (@CDilaveri) Host: Darryl S. Chutka, M.D. (@ChutkaMD)   Breast cancer is very treatable when detected early. Therefore, early detection becomes very important as it significantly reduces a patient’s risk of developing metastases and death. Breast imaging plays an extremely important role in the detection of early breast cancer, and we now have several modalities of breast imaging available, each with its advantages and disadvantages. Our guest for this podcast is Christina Dilaveri, M.D. a breast disease specialist, from Mayo Clinic’s Rochester Campus. We’ll discuss mammography, ultrasound, MRI, and molecular breast imaging, when they’re indicated, and the advantages of each. You’ll hear which patients should have more than a mammogram and how often it should be performed. Specific topics discussed: The various types of mammography available Indications for breast ultrasound Benefits of breast MRI When breast MRI should be performed Benefits of molecular breast imaging When molecular breast imaging should be performed Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 5, 2021
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Genes & Your Health Edition – Genomics and Cancer: Primary Care Impact and Research Advances

To claim credit for this series, visit: Mayo Clinic Talks Podcast: Genes & Your Health   Guest: Niloy Jewel J. Samadder, M.D. (@J_Samadder)   Host: Denise M. Dupras, M.D., Ph.D.   Can we find the cause of a patient’s cancer? Is it possible to provide targeted treatment to prevent future cancers by understanding what genetic predispositions a patient or their family members have? In a recently published study, nearly one in six to one in eight cancer patients, depending on which type of cancer they had, carried a genetic predisposition to the development of their cancer. How can we translate these findings into our practice for the benefit of our patients and their families? Tune in to episode four of our Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine. Additional resources: Samadder NJ, Riegert-Johnson D, Boardman L, et al. Comparison of universal genetic testing vs guideline-directed targeted testing for patients with hereditary cancer syndrome. JAMA Oncol. 2021;7(2):230–237. doi: 10.1001/jamaoncol.2020.6252 Uson, PLS. Riegert-Johnson, D. Boardman, L. Kisiel, J. et al. Germline cancer susceptibility gene testing in unselected patients with colorectal adenocarcinoma: a multicenter prospective study. Clin Gastroenterol Hepatol. 2021 April 20; doi: 10.1016/j.cgh.2021.04.013 Mayo Clinic’s Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 30, 2021
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The Evolution of COVID-19 Testing

Guest: Matthew J. Binnicker, Ph.D. (@DrMattBinnicker) Host: Amit K. Ghosh, M.D. (@AmitGhosh006)   In this podcast Matthew J. Binnicker, Ph.D. discusses the development of different types of testing available to diagnose SARS-CoV2 infection. Binnicker discusses the test characteristics of the rapid antigen tests and RT-PCR test and its variability based on the time when the test was performed. He also discusses the optimal timing of diagnostic testing (rapid testing, RT-PCR) and the role and limitations of antibody testing in COVID-19.   Additional resources: Shah AS, Tande AJ, Challener DW, O’Horo JC, Binnicker MJ, Berbari EF. Diagnostic stewardship: An essential element in a rapidly evolving COVID-19 pandemic. Mayo Clin Proc. 2020;95(9):S17-S19. DOI: https://doi.org/10.1016/j.mayocp.2020.05.039   Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 28, 2021
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Genes & Your Health Edition – Pharmacogenomics and its Value for Primary Care

To claim credit for this episode, visit: https://ce.mayo.edu/online-education/content/mayo-clinic-talks-podcast-genes-your-health#group-tabs-node-course-default1 Guest: Jessica A. Wright, Pharm.D., R.Ph. Host: Denise M. Dupras, M.D., Ph.D. Pharmacogenomics helps to identify how your patients’ DNA may affect their response to medications. But there's a lot of different genes! How do we get started? What resources are out there? Do we have to worry about every drug a patient is on? Find out these answers and more in episode three of the Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine. Additional resources: PharmGKB: pharmgkb.org Clinical Pharmacogenetics Implementation Consortium (CPIC®): cpicpgx.org Basic Pharmacogenomics Nomenclature: https://www.pharmgkb.org/page/glossary NIH’s National Human Genome Research Institute: Healthcare Provider Resources: https://www.genome.gov/For-Health-Professionals/Provider-Genomics-Education-Resources Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 23, 2021
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Regenerative Techniques for the Larynx

Guest: David G. Lott, M.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) About 60,000 Americans have had their vocal cords removed due to disease or trauma necessitating a laryngectomy. Post-laryngectomy, patients are unable to speak, are at risk for aspiration, and many suffer from significant anguish resulting in depression. Fortunately, there are several treatment options available, the first being laryngeal transplant. While laryngeal transplantation allows patients to smell, taste, swallow, and communicate, it has drawbacks. Currently only a small number of larynx transplants are done in the U.S., and only a select few patients with laryngectomy qualify for larynx transplant. In this episode, Dr. David Lott, division chair of laryngology at Mayo Clinic’s Arizona campus, discusses the role of regenerative medicine, which has shown promise in using 3D printing and a patient’s stem cells in creating a larynx. Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 21, 2021
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Genes & Your Health Edition – How Does Viral Genetics Influence Transmission, Diagnosis, and Severity of COVID-19?

To claim credit for this series, visit: https://ce.mayo.edu/online-education/content/mayo-clinic-talks-podcast-genes-your-health#group-tabs-node-course-default1 Guests: Andrew D. Badley, M.D. (@BadleyAndrew); Matthew J. Binnicker, Ph.D. (@DrMattBinnicker) Host: Denise M. Dupras, M.D., Ph.D. COVID-19. Variants. The future. Does one test fit all?  Will the vaccine continue to provide protection against future variants? What makes the Delta variant more transmissible? Join the second episode of our Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine to learn how viral genetics influence transmission, diagnosis, and severity of COVID-19. Additional resources: Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 16, 2021
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Genes & Your Health Edition – Genomics and Healthcare, Why Does it Matter?

To claim credit for this episode, visit: https://ce.mayo.edu/online-education/content/mayo-clinic-talks-podcast-genes-your-health#group-tabs-node-course-default1 Guests: Matthew J. Ferber, Ph.D. (@Matt_Ferber); Teresa M. Kruisselbrink, M.S., CGC (@T_Kruisselbrink); William C. Palmer, M.D. (@williampalmermd) Host: Denise M. Dupras, M.D., Ph.D. For so long we've heard Genetic Testing is coming. Well guess what, it’s here!  We have over 25 million people who have chosen to participate in direct-to-consumer testing alone. What does this mean for primary care, and does it matter? Find out in the first episode of our Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine. Additional resources: TAPESTRY Study: https://www.mayo.edu/research/clinical-trials/cls-20477323?_ga=2.268706548.460922620.1627479724-1519128218.1623079535 Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 14, 2021
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Variants, Virulence, and Vaccines, Oh My!

Guest: Elitza S. Theel, Ph.D. (@ElliTheelPhD) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Dr. Elitza Theel, Professor of Laboratory Medicine and Pathology and Director of Infectious Diseases Serology Laboratory at Mayo Clinic’s Rochester Campus, discusses our immune response to vaccination and natural infection and outlines the different types of antibody assays currently available. Dr. Theel also discusses the concept of herd immunity in the context of different circulating SARS-CoV-2 variants and the increased need to get higher rates of vaccination in the community as the infectivity and transmissibility of circulating SARS-CoV-2 variants changes. We also discuss the status of correlates of protective immunity against SARS-CoV-2 and the need for booster vaccine doses for immunocompromised individuals.  Additional resources: Interim Guidelines for COVID-19 Antibody Testing in Clinical and Public Health Settings https://www.cdc.gov/coronavirus/2019-ncov/lab/resources/antibody-tests-guidelines.html Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 7, 2021
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Evaluating Hematuria

Guest: Aaron M. Potretzke, M.D. (@potretzke)   Host: Darryl S. Chutka, M.D. (@ChutkaMD)   Microscopic hematuria, and less commonly gross hematuria, are conditions commonly seen by the primary care provider. Malignancy is the most ominous cause of hematuria. Fortunately, other causes are much more likely. Since this is a relatively common health condition, when should we investigate hematuria and what should the evaluation consist of? How do we evaluate a patient’s risk for urinary tract malignancy? Dr. Aaron Potretzke, a urologist at Mayo Clinic joins us to discuss these questions.   Specific topics: Definition of hematuria Benign causes of hematuria Risk of malignancy in low, medium, and high-risk patients Stratifying malignancy risk in patients for genitourinary malignancy Recommended evaluation for patients with hematuria How to manage patients with persistent hematuria despite a negative evaluation Role of urine cytology in the evaluation of hematuria Additional resources: American Urological Association hematuria guideline and algorithm: https://www.auanet.org/guidelines/guidelines/microhematuria Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 31, 2021
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Exercise is First-Line Treatment for Your Parkinson's Patients

Guest: Edward R. Laskowski, M.D. (@DrEdSportsMed) Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) Daily exercise has so many health and emotional benefits – it can help decrease your blood pressure, promote cardiovascular wellbeing, alleviate stress, and assist with weight loss and blood sugar control. Parkinson’s disease is a condition that affects the central nervous system, and in particular the brain, that can lead to shakiness, poor balance, and frequent falls. Joining us in this episode is Edward Laskowski, M.D., a professor of physical medicine and rehabilitation and sports medicine specialist at Mayo Clinic’s Rochester Campus, to discuss why exercise is first-line treatment for your Parkinson’s patients. Additional resources: Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055 The Michael J. Fox Foundation for Parkinson’s Research: https://www.michaeljfox.org/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 24, 2021
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Parkinson's Disease – It's More Than Just a Tremor

Guest: Jeremy K. Cutsforth-Gregory, M.D. (@JCGneuro) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Parkinson’s Disease is one of the more common neurodegenerative diseases, in fact, patients with Parkinson’s outnumber those with multiple sclerosis, ALS, and muscular dystrophy combined. It tends to affect older patients, although on rare occasions it can be seen in those under the age of 50. It can have a devastating effect on an individual’s lifestyle as the physical symptoms of the disease tend to gradually progress over years. This podcast will feature Dr. Jeremy Cutsforth-Gregory, a neurologist at the Mayo Clinic, as we discuss the evaluation and management of Parkinson’s Disease. Specific topics: Pathophysiology of Parkinson’s Disease Common presenting symptoms of Parkinson’s Assessing patients with tremor Complications of advanced Parkinson’s Pharmacologic management of Parkinson’s Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 17, 2021
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Working from the Ground Up to Impact Gender Disparities in COVID-19

Guest: Carol L. Kuhle, D.O., M.P.H. (@clkejd) Host: Anjali Bhagra, M.D. (@anjalibhagramd) Anjali Bhagra, M.D., and Carol L. Kuhle, D.O., M.P.H., discuss the narrative they recently published in Mayo Clinic Proceedings, which outlines and highlights the further widening of preexisting gender disparities in response to the COVID-19 pandemic. What can we do to identify and mitigate these issues? Additional resources: Nordhues, HC. Bhagra, A. Stroud, NN. Vencill, JA. Kuhle, CL. COVID-19 gender disparities and mitigation recommendations: a narrative review. Mayo Clin Proc. 2021 April 20; 96(7): 1907-1920. doi: https://doi.org/10.1016/j.mayocp.2021.04.009 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 10, 2021
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Mayo Clinic Q&A: The COVID-19 Delta Variant has Changed Everything

This episode is shared from Mayo Clinic Q&A and was recorded August, 2021 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd)   A fourth COVID-19 surge is blanketing the U.S., and the delta variant is the culprit. "Where did this delta variant come from? It came from unvaccinated people getting infected in large numbers allowing the virus to continue mutating," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. In the past, a person with COVID-19 might infect two to four people. But with the delta variant, one person can infect nine people, according to Dr. Poland. He says if you want to protect yourself and your family, wear a mask, especially indoors, and get vaccinated with an appropriate series of one of the COVID-19 vaccines. "These are the most studied vaccines in the history of the world," Dr. Poland emphasizes. "There have never been this many people who have received this many doses of vaccines during this amount of time with as much scrutiny as these COVID-19 vaccines have had." In this Mayo Clinic Q&A podcast, Dr. Poland answers questions about a person's waning immunity and the likelihood of COVID-19 booster shots. He also explains the two phases of immunity and goes into detail about the extensive Federal Drug Administration license approval process for COVID-19 vaccines. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 6, 2021
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Will We Be Replaced by Computers? Artificial Intelligence and Medicine

Guest: Steve G. Peters, M.D. Host: Sanjeev Kakar, M.D. (@sanjkakar) No doubt you’ve heard the term “artificial intelligence,” by now; but what is it exactly? How can medicine use AI to improve patient care and outcomes? Will it one day replace doctors’ years of training? Steve Peters, M.D. a pulmonary and critical care medicine consultant, with a special interest in AI, at Mayo Clinic’s Rochester campus. Dr. Peters will help us take a look into the not-so-distant future as we explore AI and its role in medicine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 3, 2021
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Mayo Clinic Q&A: Stopping the Spiral of the COVID-19 Delta Variant

This episode is shared from Mayo Clinic Q&A and was recorded July, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    Transmission of the COVID-19 delta variant is increasing. "We're in this constant spiral, right now,” says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. “The delta variant is so highly contagious,” he says. “The number of delta viral particles in the upper respiratory system is reportedly 1,000 times higher than with the original COVID-19 virus. If we can't find ways to get people vaccinated, we are going to be in a world of hurt. And I don't say that to be alarmist. I say it to be a realist, based on what’s happening right in front of us.” But Dr. Poland says the spiral can be stopped by getting higher rates of immunization.  "Getting a COVID-19 vaccine will prevent the development of worse and worse variants. It will prevent severe cases of hospitalization and death, even in the face of a variant,” he says. "The alternative is to lose another 600,000-plus Americans. Only this time it will, unfortunately, involve younger people." Dr. Poland explains further, "Every time somebody gets infected with the delta variant, there's the opportunity for that virus to mutate and transmit to other people," says Dr. Poland. "This means that immunization rates to control herd immunity will probably have to be in the 85% to 95% range." In this Mayo Clinic Q&A podcast, Dr. Poland continues to talk about the delta variant, breakthrough infections, booster shots and much more. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 30, 2021
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What’s That Sound? Maybe It’s Stridor

Guest: Shelagh A. Cofer, M.D. (@ShelaghCoferMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Stridor is a musical sound due to disrupted airflow in an individual’s airway. In many instances it’s due to a benign cause but it can also represent a serious problem, possibly even life-threatening. In today’s podcast, we’ll learn about the various causes of stridor and when we need to be concerned that it represents a serious health issue. Our guest for this podcast is Dr. Shelagh Cofer, a pediatric otolaryngology specialist at the Mayo Clinic. We’ll discuss how stridor differs from wheezing, the most common causes of stridor in both children and adults and what symptoms we should be watching for that might suggest a serious cause for stridor. We’ll also cover the evaluation of patients with stridor, which imaging studies may be helpful and when an ENT consultation is warranted. Specific topics: Definition of stridor Difference between stridor, stertor, and wheezing Most common causes of stridor in both children and adults Croup as a form of stridor Important questions we should be asking our patients about stridor to identify those at risk for airway obstruction – including the SPECS-R mnemonic Tests and imaging studies which may be helpful in the evaluation of a patient with stridor Treatments for the more common causes of stridor Additional resources: Zoumalan, R; Maddalozzo, J; Holinger, LD. Etiology of stridor in infants. Ann Otol Rhinol Laryngol. 2007; 116(5):329-334. doi: 10.1.1896.429 https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.896.429&rep=rep1&type=pdf Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 27, 2021
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Mayo Clinic Q&A: On the Verge of Predicted COVID-19 Surge with Delta Variant

This episode is shared from Mayo Clinic Q&A and was recorded July, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    The delta variant is being blamed for hot spots in the U.S. where cases of COVID-19 are on the rise. These hot spots account for most cases in the U.S. They are also the geographical areas that tend to have the lowest vaccination rates.  "It's no surprise that the two go together," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "This (delta variant) is the bad actor that we predicted it would be," adds Dr. Poland. "Our seven-day average is getting up to 19,000 cases a day in the U.S. We were down to 3,000. So we're starting to see, just as we predicted, a surge as people took masks off and as restrictions were lifted before we had achieved high rates of immunization." In this Mayo Clinic Q&A podcast, Dr. Poland expands on how the highly transmissible delta variant continues to spread. He also talks about the possibility of COVID-19 vaccine boosters, explains how the Vaccine Adverse Event Reporting System works, and much more as he answers listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 22, 2021
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Multidisciplinary Approach to Pelvic Pain

Guest: Isabel C. Green, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Pelvic pain can be challenging. It can have a variety of presenting symptoms since it can originate from a variety of organ systems. When pelvic pain becomes chronic, it becomes even more challenging. It’s associated with significant direct medical costs as well as indirect costs as it frequently results in work absenteeism. Patients with chronic pelvic pain are often initially evaluated by primary care providers, but referral to specialists is quite common. Due to the variety of symptoms associated with chronic pelvic pain, multiple specialties often are asked to evaluate these patients. This frequently results in patients being passed back and forth between various medical specialties. It therefore becomes important for primary care providers to become comfortable evaluating and managing patients with pelvic pain. Our guest for this podcast is Dr. Isabel Green, a physician from the Department of Obstetrics and Gynecology at the Mayo Clinic. We’ll discuss how to effectively evaluate patients with pelvic pain, “red flag symptoms” to watch for, useful laboratory tests to order, and common imaging studies which can be helpful in establishing a cause for the pain. We’ll also discuss the benefits of a multi-disciplinary approach to pelvic pain. Specific topics: Categorization of pelvic pain Appropriate evaluation of pelvic pain including the clinical history, physical exam, laboratory tests and imaging studies Relationship of chronic pelvic pain with other symptoms such as anxiety, depression, insomnia, and work/relationship issues Chronic pelvic pain representing a form of centralized pain Advantages of a multi-disciplinary approach to evaluating and managing chronic pelvic pain Additional resources: Chronic pelvic pain: ACOG practice bulletin, number 218. Obstet Gynecol. 2020 Mar; 135(3):e98-e109. doi: 1097/AOG.0000000000003716. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 20, 2021
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Identifying and Treating Urinary Urge Incontinence

Guest: Brian J. Linder, M.D. (@brianjlinder) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Patients rarely mention urinary incontinence to us as a problem as many assume it’s a normal change of aging. However, it’s a major quality-of-life issue. Many with incontinence are reluctant to go out in public and those who do, usually know the location of all the nearby restrooms. Yet, with proper evaluation and treatment, essentially all patients can be helped, and in many cases, they can be cured. In this podcast, we’ll discuss urgency urinary incontinence, one of the most common forms of incontinence. We’ll cover the questions you should ask your patients to make a diagnosis, what evaluation you should do, and what treatment options are available. Our guest for this topic is Dr. Brian Linder, a urologist at the Mayo Clinic. Specific topics: The various types of urinary incontinence Important questions to ask patients to make a diagnosis Effective use of a voiding diary Physical exam recommendations Helpful laboratory tests When urodynamic studies are indicated Non-pharmacologic treatment options Medications useful in treating urgency incontinence Treatment options for the refractory patient Additional resource: https://www.auanet.org/guidelines/overactive-bladder-(oab)-guideline Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 13, 2021
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Mayo Clinic Q&A: Summer Travel and People Not in Your Bubble During COVID-19 Pandemic

This episode is shared from Mayo Clinic Q&A and was recorded June, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    "The reason we have the COVID-19 delta variant, the reason we have the delta plus variant is because of unimmunized people who get infected," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. He adds that 99.2% of the recorded COVID-19 deaths in the U.S. are in people not vaccinated against the virus.  This is why he cautions folks who may be traveling this Fourth of July holiday and throughout the summer.  "You don't know what variants people are carrying, how symptomatic they are, the health of their immune system, or if they've been vaccinated," says Dr. Poland. "When you are around groups of people indoors that are not in your bubble, so to speak, I think you should still wear a proper mask."  In this Mayo Clinic Q&A podcast, Dr. Poland explains why, even if you are fully vaccinated for COVID-19, you should still consider being masked in some situations. He also discusses breakthrough infections in certain subpopulations, and what that may mean for needing booster shots. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 7, 2021
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Postural Orthostatic Tachycardia Syndrome (POTS) in Adult Patients

Guest: Jeremy K. Cutsforth-Gregory, M.D. (@JCGneuro) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Postural Orthostatic Tachycardia Syndrome, or POTS, is a medical condition manifested by tachycardia that occurs after standing or prolonged sitting and is often associated with symptoms such as dizziness, fatigue, and occasionally syncope. POTS can be difficult to diagnose as patients often present with a variety of vague, and what seem like unrelated, symptoms. Management of patients with POTS can be equally difficult as there’s no one treatment which is effective in all patients. However, patients with POTS often have typical symptoms and objective findings on physical exam. Once a diagnosis is made, effective treatment is available and many patients with POTS can be helped with non-pharmacologic therapy. To help us understand POTS and its management, we’ll speak with Dr. Jeremy Cutsforth-Gregory, a neurologist at the Mayo Clinic. We’ll discuss the proposed theories regarding the cause of POTS, the different types of POTS, pathologic findings in patients with POTS, and the management of patient with POTS. Specific Topics: Typical symptoms of POTS Risk factors for POTS Theories regarding the cause of POTS Description of the varieties of POTS How to diagnose POTS Pathologic and pharmacologic abnormalities related to POTS Management of patients with POTS Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 6, 2021
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Regenerative Medicine Edition Ep.10: FDA Regulatory Process and Clinical Trials

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Drew M. Witter, CCRP Host: Darryl S. Chutka, M.D. (@ChutkaMD) “Stem Cell Clinics” throughout the U.S. promote stem cell therapy for a variety of health conditions including osteoarthritis, autism, macular degeneration, Parkinson’s Disease, Alzheimer’s Disease and most recently COVID-19 infections. How can our patients be assured that the regenerative medicine therapy effectively treats their health condition and the products they receive are safe? In this podcast, we discuss regulations regarding regenerative medicine, the process of obtaining FDA-approval and which regenerative medicine therapies are FDA-approved. Our guest will be Drew Witter, a Program Manager from the Office of Research and Regulatory Support at the Mayo Clinic. Specific topics discussed: Process of taking regenerative medicine from the research lab to the clinical practice How regulators ensure the safety and effectiveness of regenerative therapies The process of acquiring FDA-approval Regenerative medicine therapies that are FDA-approved How patients and clinicians learn of FDA-regulated regenerative medicine clinical trials Additional resources: Clinical Trials available at Mayo Clinic through the Center for Regenerative Medicine: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-trials U.S. National Library of Medicine: https://www.clinicaltrials.gov/ Center Watch: https://www.centerwatch.com/ Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
July 1, 2021
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Primary Care Management of the Post-Prostate Cancer Patient

Guest: Matthew K. Tollefson, M.D. (@MattTollefsonMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Other than skin cancer, prostate cancer is the most common cancer in men in the United States and will affect 1 in every 6 men 65 years and older. Fortunately, when detected early, it is very treatable. Long-term follow-up of patients with treated prostate cancer is usually performed by primary care providers. How often should these patients be seen? How much of an exam is recommended? Which tests should be ordered? When are imaging tests indicated and which studies are the most helpful? This podcast will address these questions and more as we discuss the primary care management of the post-prostate cancer patient with Dr. Matthew Tollefson, a urologist from the Mayo Clinic. Specific topics discussed: Current treatment options for prostate cancer Determinants for choosing one of the treatment options for prostate cancer When and how often patients should receive follow-up for prostate cancer Laboratory tests recommended for the follow-up of prostate cancer patients When a detectable PSA is concerning following prostate cancer treatment Imaging studies recommended for following prostate cancer patients and when they are indicated Treatment options for recurrent prostate cancer Future treatment options for prostate cancer which have potential Additional resources: https://www.auanet.org/guidelines/advanced-prostate-cancer https://www.mayoclinic.org/diseases-conditions/prostate-cancer/symptoms-causes/syc-20353087 https://www.mayoclinic.org/medical-professionals/urology Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 29, 2021
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Mayo Clinic Q&A: COVID-19 Vaccination Rates Stalling, Infections From the Delta Variant Rising

This episode is shared from Mayo Clinic Q&A and was recorded June 21, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    Summer and fall are going to be a dangerous time for people in the U.S. who have not been vaccinated for COVID-19, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.  "I really think this exponential rise in the number of sequences that are delta must be taken seriously," says Dr. Poland. "We are seeing a surge again, in hospitalizations in the UK, because of the delta variant in people who have not been vaccinated or who only got one dose of vaccine. This is a really critical message for the public to hear because in the U.S. we are stalled in vaccination rates." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about a possible COVID-19 surge and being emotionally ready for the pandemic to be over. He also answers listener questions about COVID-19 reinfection, the latest on antiviral development for COVID-19, and the latest news about COVID-19 vaccines affecting menstrual cycles and sperm quality. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 25, 2021
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Regenerative Medicine Edition Ep.9: Cardiac Regenerative Therapies

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Atta Behfar, M.D., Ph.D. (@AttaBehfar) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Traditional treatment of cardiac disease, especially advanced congestive heart failure has been limited. Transplantation has potential for benefit; however, organ shortage remains a barrier. It’s anticipated that regenerative medicine will help solve this unmet need with new treatment options to repair damaged heart tissue. This podcast will discuss regenerative medicine for cardiovascular disease with Dr. Atta Behfar, a Mayo Clinic cardiologist with expertise in advanced heart failure and transplantation. We’ll review the progress made in regenerative medicine in management of cardiovascular disease, what treatment options are currently available and the potential treatment options which will become available in the future. Specific topics discussed: Regenerative potential of the cardiovascular system Current challenges in management of patients with cardiovascular disease Progress in regenerative medicine for the cardiovascular system Limitations in regenerative cardiac therapy using regenerative medicine Future potential for regenerative medicine treatment of cardiovascular disease Patients who are candidates for cardiac regenerative therapies  Additional resources: Clinical Trials available at Mayo Clinic through the Center for Regenerative Medicine: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-trials U.S. National Library of Medicine: https://www.clinicaltrials.gov/ Center Watch: https://www.centerwatch.com/  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 24, 2021
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Mayo Clinic Q&A: Examining Reports of Heart Inflammation in Young People After Second COVID-19 Vaccine

This episode is shared from Mayo Clinic Q&A and was recorded June 14, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices is holding an emergency COVID-19 meeting this week to discuss COVID-19 vaccine safety as it relates to news that young people may develop myocarditis after receiving a second dose of a messenger RNA COVID-19 vaccine. Myocarditis, which is an inflammation of the heart muscle, is usually caused by a viral infection. But it can result from a reaction to a drug or be part of a more general inflammatory condition. Signs and symptoms include chest pain, fatigue, shortness of breath and arrhythmias. "There have been about 789 cases reported," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And that can happen for a whole variety of reasons."  In this Mayo Clinic Q&A podcast, Dr. Poland details the concerns about the myocarditis reports. He also discusses the latest news on the COVID-19 delta variant, and he explains what scientists are calling the "two-track pandemic." AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 23, 2021
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The Sobering Statistics of Alcohol Use Disorder

Guest: Terry D. Schneekloth, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) According to the 2019 National Survey on Drug Use and Health, nearly 26% of individuals 18 and older reported that they engaged in binge drinking and slightly over 6% engaged in heavy alcohol use within the past month. Binge drinkers were 70 to 90 times more likely to have an alcohol-related emergency department visit. Based on their data from this study, they estimated that nearly 15 million people ages 12 and older had alcohol use disorder. It’s also known that those with alcohol use disorder commonly seek care from primary care providers for alcohol-related medical problems. Our guest for this podcast is Terry Schneekloth, M.D., a psychiatrist and addiction specialist at Mayo Clinic. Specific topics discussed: Definition of alcohol use disorder Risk factors for alcohol use disorder Role of genetics Questions primary care providers should ask to explore the possibility of an alcohol use disorder in patients Physical exam or lab findings which could suggest an alcohol use disorder Available treatment options and their alcohol use disorder effectiveness Additional Resources: World Health Organization (WHO). Alcohol Use Disorders Identification Test (AUDIT). 2001 November 18; https://www.who.int/publications/i/item/audit-the-alcohol-use-disorders-identification-test-guidelines-for-use-in-primary-health-care National Institute on Alcohol Abuse and Alcoholism (NIAAA). National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study: https://www.niaaa.nih.gov/research/nesarc-iii Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 22, 2021
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Regenerative Medicine Edition Ep.8: Neuroregenerative Therapies

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Nathan Staff, M.D. (@NathanStaffMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The cells in our nervous system are extremely specialized, especially those in the brain. Unfortunately, nervous tissue does not have a great potential to regain function once it is lost. Exciting research is being done in the field of neuro-regenerative medicine which will give hope for improvement to those with chronic neurodegenerative disease or nerve damage from injury. Dr. Nathan Staff, a Mayo Clinic neurologist, joins us regarding the challenges with the current management of chronic neurodegenerative diseases and the future potential for treating such conditions as Parkinson’s Disease, Alzheimer’s Disease, ALS and other neurodegenerative disease with regenerative medicine therapies. Specific topics discussed: Current research in regenerative medicine treatment for chronic neurodegenerative disease Currently used regenerative medicine in neurologic conditions New treatment options on the horizon for chronic neurodegenerative disease using regenerative medicine therapy  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 17, 2021
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The Agony of Da Feet – Assessing Foot and Ankle Pain and Injury

Guest: Daniel B. Ryssman, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Generally, we take our feet for granted. It’s not unusual for a person to take 8- to 10-thousand steps per day. That translates to over 115,000 miles in a lifetime. By the time we reach 70 years old, the average person will have walked the equivalent of 4 times around the globe. Yet, we stop taking our feet for granted when they hurt, and it’s estimated that 75% of Americans will experience foot problems of varying degrees of severity during their lifetime. In this podcast, we’ll discuss foot and ankle pain with Daniel Ryssman, M.D., an orthopedist and sports medicine physician from Mayo Clinic. We’ll review some of the common injuries to the ankle such as sprains and fractures as well as common chronic conditions of the foot such as plantar fasciitis and bunions. Dr. Ryssman delves into the best ways to prevent, diagnose, and treat these conditions as well as what, if any, imaging to order. Specific topics discussed: Ankle sprains Ankle fractures Achilles’ tendon rupture Plantar fasciitis Bunions Metatarsalgia Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 15, 2021
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COVID-19 Miniseries Episode 75: Mayo Clinic Q&A – A Dangerous Phase of the COVID-19 Pandemic for Those who are Unvaccinated

This episode is shared from Mayo Clinic Q&A and was recorded June, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    If you've been vaccinated for COVID-19, you're able to go shopping, eat in restaurants and travel on airplanes without the same worry of becoming infected with COVID-19 that existed just months ago. But for those who are unvaccinated, getting infected with COVID-19 — even with just minor symptoms — should be a concern, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "For those who have been vaccinated, life is resuming back to a sense of normalcy," says Dr. Poland. "But for the unvaccinated, they now live in a dangerous phase of the pandemic, where we're seeing circulating variants that are much more transmissible and may cause worse cases of the disease than what happened last year at this time. I think the people who are unvaccinated may not realize that." In this Mayo Clinic Q&A podcast, Dr. Poland also offers information on more COVID-19 studies underway and he talks about COVID-19 vaccine research protocols that will be able to help scientists with other vaccine research, such as HIV vaccine research. Also, he answers listener questions, such as, "Does someone who has already been infected with COVID-19, really need to be fully vaccinated for COVID-19 or would just a booster be needed?" AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 11, 2021
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Regenerative Medicine Edition Ep.7: Preventing Osteoarthritis of the Knee

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Daniel Saris, M.D., Ph.D. (@sarisnl) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Osteoarthritis of the knee is extremely common, and it’s estimated that 1 in 2 people are likely to develop symptomatic knee osteoarthritis in their lifetime. Its known that damaged cartilage is the precursor to osteoarthritis. Many individuals have had partial or complete meniscectomies for meniscal tears in the past and those individuals were then likely to eventually develop knee osteoarthritis. What if damaged cartilage was repaired instead of surgically removed? Could that be an effective treatment recommendation we could give to our patients to help prevent or treat osteoarthritis? Our podcast guest today is Dr. Daniel Saris and he has some fascinating information related to cartilage damage and repair using regenerative medicine techniques. Specific topics discussed: How meniscal damage relates to osteoarthritis Ability of cartilage to repair itself when damaged Repairing a damaged meniscus instead of a partial or complete meniscectomy Specific techniques of repairing cartilage Success in treating patients with cartilage repair Future treatment options for osteoarthritis using regenerative medicine  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 10, 2021
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COVID-19 Miniseries Episode 74: The World is Flat – Addressing Anosmia in Post-COVID Patients

Guest: Erin K. O'Brien, M.D. (@ErinOBrienMD)  Host: Amit K. Ghosh, M.D. (@AmitGhosh006)  Erin O’Brien, M.D., division chair of Rhinology in Rochester, MN, joins us again to provide an evidence-based update on anosmia and its prevalence in post-COVID patients. She reviews the postulated mechanism by which anosmia occurs in this group of patients, and how this effects patients’ safety, mental health, and overall wellbeing. Dr. O’Brien also gives an overview of treatment options, such as various methods of olfactory training, and what physicians need to know when counseling their patients with post-COVID anosmia.  Additional resources:  Video on olfactory training: https://www.youtube.com/watch?v=Qrr0so6pFOs  Abscent – resources for patients with anosmia: https://abscent.org/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 8, 2021
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Regenerative Medicine Edition Ep.6: New Options for Treating Musculoskeletal Pain

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Shane A. Shapiro, M.D. (@ShaneShapiroMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Musculoskeletal pain is extremely common and when severe, patients often gain significant benefit from joint replacements. However, until our patients reach the point where surgery is an option, our efforts to help patients with the chronic joint pain often leave much to be desired. A relatively new treatment approach has appeared in the past decade, musculoskeletal regenerative medicine. But does the research back up the numerous claims of benefit? This podcast will review the current treatment options available and future potential of regenerative medicine for musculoskeletal problems with Dr. Shane Shapiro, a sports medicine physician in the Department of Orthopedics at the Mayo Clinic. We’ll discuss the current regenerative products and therapies available to optimize patient outcomes, potential adverse effects of the therapies and the numerous claims by many clinicians regarding the benefit potential for regenerative medicine in musculoskeletal disease.  Specific topics discussed: Challenges of currently available traditional treatment for musculoskeletal conditions Benefits of stem cell injections for osteoarthritis Potential adverse effects of stem cell injections Currently available regenerative medicine therapies that have shown benefit to patients Validity of the many claims made by clinicians regarding the benefits of stem cell injections  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 3, 2021
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Watching Out for Loperamide Abuse

Guest: Tyler S. Oesterle, M.D., M.P.H. (@OesterleMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Opioid abuse remains a significant problem, and as law enforcement and regulatory agencies tighten access to prescription analgesics, individuals are seeking alternatives. It’s been discovered that when taken at very high doses, loperamide can produce similar effects to the opioid analgesics and the drug is inexpensive when compared to the price of both illicit and prescription opioids. As a result, loperamide abuse has become a significant problem. In this episode we discuss loperamide abuse with Tyler Oesterle, M.D., M.P.H., a psychiatrist at Mayo Clinic’s Rochester campus. We’ll review the typical central nervous system effects of high dose loperamide and the associated safety issues. Specific topics: Current status of the opioid crisis in the U.S. Effects of loperamide in both therapeutic and excessive doses Reasons behind taking high dose loperamide in excessive doses Safety issues associated with high dose loperamide Potential of high dose loperamide leading to drug dependence Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
June 1, 2021
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COVID-19 Miniseries Episode 73: Mayo Clinic Q&A – Dissecting COVID-19 Research and Putting Data in Perspective

This episode is shared from Mayo Clinic Q&A and was recorded May 24, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    The number of COVID-19 cases, hospitalizations and deaths in the U.S. continues to decline. However, cases of COVID-19 are increasing in younger populations.  "It's becoming a childhood disease," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Children have composed over 16,000 hospitalizations for COVID-19 and about 300 have died." Meanwhile, each day brings fresh research news, including updates on possible side effects of the COVID-19 vaccines.  "We're collecting information as we go and have data on about 4.5 million people now," says Dr. Poland. "That's larger than we would have for any other vaccine."  In this Mayo Clinic Q&A podcast, Dr. Poland expands on these latest news items and puts the data in perspective. He also discusses vaccination rates, the possibility of mixing and matching vaccines for COVID-19 boosters, vaccination rates, and much more. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 28, 2021
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Regenerative Medicine Edition Ep.5: The Mission for Fluency and Safeguarding Patients from Stem Cell Tourism

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Saranya Wyles, M.D. (@SWylesMDPhD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Much of regenerative medicine is relatively new and some of the future treatment capabilities have the potential to significantly change the way we practice medicine. How do you educate established clinicians as well as clinicians in training regarding this new practice? How do you educate the general public which has been misled by a variety of false claims regarding which medical conditions regenerative medicine can currently effectively treat? This podcast discusses how a relatively new medical field puts together an education program to inform others of its potential. Our guest is Saranya Wyles, M.D., a resident in the Department of Dermatology who has considerable experience in regenerative medicine education.  Specific topics discussed: Specific groups who need educating regarding the capabilities of regenerative medicine The importance in training the medical workforce regarding regenerative medicine What regenerative medicine means for the next generation of healthcare providers How to incorporate regenerative medicine concepts into an established medical school curriculum How to educate more advanced learn years such as residents and healthcare providers Obtaining an advanced degree in the field a regenerative medicine Additional resources: International Society for Stem Cell Research (ISSCR): https://www.isscr.org/ The ISSCR Patient Handbook on Stem Cell Therapies: https://www.closerlookatstemcells.org/patient-resources/ Regenerative medicine curriculum for next-generation physicians: https://www.nature.com/articles/s41536-019-0065-8 Digital regenerative medicine and surgery pedagogy for virtual learning in the time of COVID-19: https://www.futuremedicine.com/doi/full/10.2217/rme-2020-0106 Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 27, 2021
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COVID-19 Miniseries Episode 72: Mayo Clinic Q&A – Guidelines and Nuances of Wearing a Face Mask

This episode is shared from Mayo Clinic Q&A and was recorded in May, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    Recent COVID-19 masking guidelines announced by the Centers for Disease Control and Prevention, continue to generate a public conversation. "The decision about masking needs to be nuanced," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Wearing a mask should be based on the risk of infection, the percentage of the population vaccinated, a person's own immune system, and then the role of vaccine variants with the durability of our immune response." In this Mayo Clinic Q&A podcast, Dr. Poland discusses masking guidelines in further detail. Also, he offers an update on COVID-19 vaccine research for children, and he shares positive news about the decreasing numbers of COVID-19 cases and deaths. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 26, 2021
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The M.I.A.M.I. Approach to Deciphering Lymphadenopathy

Guest: Carrie A. Thompson, M.D. (@CaThompsonMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) It’s common for a patient to see their primary care provider after they’ve discovered an enlarged lymph node and they’re usually concerned that it represents a serious illness. Fortunately, in most cases it’s due to a benign cause and most patients can be reassured once we perform a careful history and physical examination. However, on occasion lymphadenopathy can represent serious disease. Carrie Thompson, M.D. a hematologist, at Mayo Clinic’s Rochester campus joins us to discuss how to tell when lymphadenopathy is due to a benign or serious cause. We’ll review the characteristics of both benign and malignant lymph nodes and the evaluation which should be done both for an enlarged solitary lymph node as well as generalized lymphadenopathy. Specific topics discussed: Prevalence of malignancy in patients who seek a medical evaluation for lymphadenopathy Categories of disease which can have associated lymphadenopathy Characteristics of benign and malignant lymph nodes Diagnostic approach for a solitary enlarged lymph node Diagnostic approach or multiple or generalized lymphadenopathy Fine needle aspirate vs. excisional biopsy for evaluation of lymphadenopathy Additional resources: Gaddey, HL. Riegel, AM. Unexplained lymphadenopathy: evaluation and differential diagnosis. Am Fam Physician.2016 December 1; 94(11): 896-903. https://www.aafp.org/afp/2016/1201/p896.html Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 25, 2021
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Regenerative Medicine Edition Ep.4: The Curative Potential of Immunotherapy

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Saad J. Kenderian, M.B., Ch.B. (@kenderian_ss) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Regenerative immunotherapy is a treatment that uses the power of our own immune system to fight malignancy. It can include targeted antibodies, cancer vaccines, or tumor infecting viruses to name a few. Some immunotherapy treatments use genetic engineering to enhance our immune cell’s cancer fighting properties and can be used in combination with more traditional treatments including surgery, chemotherapy, or radiation. It’s FDA-approved as a first line treatment of multiple cancers and may also be effective in the management of malignancies that have been resistant to more traditional therapy. This podcast will address regenerative immunotherapy with Dr. Saad Kenderian, a hematologist at the Mayo Clinic. We’ll review the relationship between cancer and our immune system, how we can use our immune system to treat malignancy and which malignancies which have shown the best responses to regenerative immunotherapy.  Specific topics discussed: Relationship between cancer and our immune system How we can use our body’s immune system to fight malignancy Malignancies which can be currently be effectively treated with regenerative immunotherapy Malignancies which have had the best responses to regenerative immunotherapy Limitations in regenerative immunotherapy  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.  
May 20, 2021
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Identifying Breast Cancer in Men

Guest: Kathryn J. Ruddy, M.D. (@KathrynRuddyMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Breast cancer in men is very uncommon, about 1/100th as common as in women. It’s expected that this year, just under 3000 men are likely to be diagnosed with it, and just over 500 men will die from breast cancer. Because it’s so uncommon, there are very few good studies which have been completed to educate us about this disease. Kathryn Ruddy, M.D., an oncologist at Mayo Clinic’s Rochester campus joins us to discuss breast cancer in men and what we should do as primary care clinicians to care for our male patients who may be at increased risk to develop it. We’ll cover how breast cancer in males differs from that in females, its risk factors, how it’s diagnosed, and the survival rates of men with a diagnosis of breast cancer. Specific topics: Prevalence of breast cancer How most breast cancers in men are found The recommended evaluation of a male patient with suspected breast cancer Risk factors for breast cancer in men Treatment for male breast cancer Survival rates for breast cancer in men Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 18, 2021
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Regenerative Medicine Edition Ep.3: Perspectives in Reconstructive Surgery

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Richard E. Hayden, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Currently reconstructive surgery involves taking the patient’s tissue from one area of their body and using it elsewhere to rebuild diseased or damaged tissue. Regenerative reconstructive surgery will allow the patient to grow their own replacement tissue from stem cells. This has incredible potential for allowing significantly better reconstructive surgical results. Currently regenerative reconstructive surgery is in its infancy, however in the next several years this should develop into a new standard of care for patients who need reconstructive surgery. This podcast features Dr. Richard Hayden, a reconstructive surgeon/otolaryngologist. We discuss the future of reconstructive surgery using regenerative medicine techniques, the difficulties in enabling patient access to regenerative therapies, the education that’s needed for not only providers but also for patients, and the future of regenerative reconstructive surgery. Specific topics discussed: Role regenerative medicine plays and reconstructive surgery Importance in adopting and delivering regenerative care Challenges in current standard of care approaches in reconstructive surgery Difficulties enabling patient access to regenerative therapies Educational needs in regenerative reconstructive surgery The future of regenerative reconstructive surgery Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 13, 2021
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What You Need to Know About Eustachian Tubes and Tonsils

Guest: Laura J. Orvidas, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Tonsils and eustachian tubes often get taken for granted until they cause problems. Eustachian tube dysfunction is quite common and usually resolves on its own, however some patients will develop recurrent eustachian tube dysfunction and it can result in recurrent episodes of otitis media, especially in children. Although recurrent tonsillitis used to be the most common indication for tonsillectomy, more children are having this procedure for disordered breathing conditions, such as obstructive sleep apnea. In this episode, we’ll discuss disorders of the eustachian tube and tonsils with Laura J. Orvidas, M.D., an otolaryngologist at the Mayo Clinic. Specific topics discussed: Purpose of the eustachian tube Definition of eustachian tube dysfunction Physical exam findings of eustachian tube dysfunction Recurrent eustachian tube dysfunction in children and potential for recurrent episodes of otitis media When pressure equalization tubes are indicated Relationship between pharyngitis and tonsillitis Viral versus bacterial causes of tonsillitis How to suspect a peritonsillar abscess Indications for tonsillectomy Management of tonsil stones Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 11, 2021
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COVID-19 Miniseries Episode 71: Mayo Clinic Q&A – Ramping up COVID-19 Vaccination Rate in Race Against Virus

This episode is shared from Mayo Clinic Q&A and was recorded in May 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: DeeDee Stiepan (@deedeestiepan) COVID-19 cases are falling in the U.S. because 245 million doses of one of the available COVID-19 vaccines have been administered, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "But at the same time, there are still people who need more information about the safety and the value of getting a COVID-19 vaccine," says Dr. Poland. While still hopeful, Dr. Poland says he's concerned herd immunity won't be reached in the U.S. through vaccination. And that will mean more tragic deaths due to COVID-19 infection. "My guess is, because we're such an interconnected global community until everybody's safe, none of us are safe. And we're going to likely see continued circulation of the virus, and that virus will seek out whoever is not immune," says Dr. Poland. In this Mayo Clinic Q&A podcast, Dr. Poland also addresses when we will need COVID-19 vaccine boosters will be needed and the latest on masking guidelines from the Center for Disease Control and Prevention. Plus, he will provide an update on COVID-19 treatments and how to handle those who want to visit a newborn baby. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 7, 2021
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Regenerative Medicine Edition Ep.2: Between Hype and Hope – What’s Really Possible?

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Dennis Wigle, M.D., Ph.D. (@DrWigle) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Regenerative Medicine has some amazing capabilities and in the near future, it’s likely to significantly change how we practice medicine. It faces some challenges in educating both the medical community as well as the general public regarding its current realistic capabilities. There are many unsubstantiated claims made by practitioners to the public regarding the benefits of regenerative medicine therapy. We’ll discuss how the true potential of regenerative medicine is conveyed to both clinicians and the public with Dr. Dennis Wigle, a thoracic surgeon and chair of the Division of General Thoracic Surgery at the Mayo Clinic. We’ll discuss some of the common misperceptions of regenerative medicine and how a consultation service can educate both the public and medical community regarding the benefits of regenerative medicine. Specific topics discussed: How to provide education to the public and the medical community When and why the regenerative consultation service was formed How the regenerative medicine consultation service works Common misperceptions community regarding the realistic benefits of regenerative medicine  Additional resources: For more information about Mayo Clinic’s Regenerative Medicine Consult Service, visit: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/regenerative-medicine-consult-service  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 6, 2021
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Regenerative Medicine Edition Ep.1: Transforming Care Towards Curative Solutions

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Fredric B. Meyer, M.D.; Andre Terzic, M.D., Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Imagine a patient who has suffered a massive myocardial infarction leaving a significant amount of damaged and non-functioning ventricular myocardium. Treatment for this patient’s subsequent congestive failure does not involve diuretics and beta blockers but rather an injection of the patient’s modified stem cells into surrounding viable ventricular myocardium resulting in the regeneration of new, functioning myocardial cells restoring the cardiac output. This is not science fiction but represents ongoing work by investigators in Regenerative Medicine. This week’s podcast will explore this amazing field of medicine which has the potential to change how medicine is practiced. We’ll discuss the origins of regenerative medicine, what currently be done in regenerative medicine as well as the potential for the future. Our guests today are Andre Terzic, M.D., Ph.D., director of the Mayo Clinic Center for Regenerative Medicine and Fredric B. Meyer, M.D., a neurosurgeon and the Executive Dean for Education at the Mayo Clinic.  Specific topics discussed: When the field of regenerative medicine began Which current medical conditions can currently be managed with regenerative medicine How to determine which patients have potential for regenerative medicine therapies Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 4, 2021
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Mayo Clinic Q&A: COVID-19 Vaccine Confidence and the Importance of That Second Dose

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  While the number of people being vaccinated for COVID-19 is dropping, the Centers for Disease Control and Prevention and other medical experts continue to strongly encourage people to get vaccinated for COVID-19. And that means that those who are being vaccinated with the Moderna and Pfizer COVID-19 vaccine should get their first and second doses on schedule. “About 8% of people who got their first dose have not returned for the second dose and this is concerning when you're getting close to 1 in 10," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "When you measure in the short term, one dose in a healthy person offers about 80% protection. But that's not 95% protection, like you get after two doses." In this Mayo Clinic Q&A podcast, Dr. Poland expands on why people need that second COVID-19 vaccine dose and he talks about whether people should mix and match the different COVID-19 vaccines for their second dose. He also speaks about the status of COVID-19 vaccines for young people, and he addresses listener questions about traveling, being together after vaccination, and the latest rise of additional COVID-19 variants. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 29, 2021
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Fact or Fiction: Erectile Dysfunction Treatments

Guest: Tobias S. Kohler, M.D., M.P.H. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Erectile dysfunction not only causes lifestyle changes, but it may also be the first symptom of peripheral vascular disease. Since many men are reluctant to mention erectile dysfunction to their healthcare provider, it’s important for us to ask our patients whether it is a problem and be knowledgeable in the appropriate evaluation of patients who have it. This reluctance may cause many to seek out readily available but ineffective treatments from questionable sources, even though there are a variety of proven, effective treatments that can be prescribed. Tobias S. Kohler, M.D., M.P.H., a Mayo Clinic Urologist, joins us to discuss the impact of erectile dysfunction, the currently available effective treatments, as well as the unproven, ineffective products currently being used. Specific topics discussed: The first historical appearance of treatments for erectile dysfunction Most common causes of dysfunction Appropriate evaluation of patients who present with erectile dysfunction Review of the currently available effective treatment options Reasons men are reluctant to mention the topic of erectile dysfunction to their provider Review of some ineffective treatments currently being promoted Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 27, 2021
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COVID-19 Miniseries Episode 70: Mayo Clinic Q&A – Breakthrough COVID-19 Infections and Booster Vaccines

This episode is shared from Mayo Clinic Q&A and was recorded on April 19, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group says COVID-19mutations and the virus spread are happening because of people who don't wear masks, who don't get vaccinated and who don't adhere to safety recommendations. "I believe that we should be radically transparent and honest," says Dr. Poland. "The more time this virus passes through one person after another, the more likely it continues to mutate. As a result of those mutations, two things are happening. Some of the mutations are making vaccines and plasma monoclonal antibodies less effective. The other thing is that the virus will likely become something that we have to live with for the rest of our lives." Dr. Poland reminds people that vaccine protection is not 100%. Breakthrough infections can occur. "Remember that in the clinical trials, 95% means that compared to unvaccinated people, your risk is reduced by 95% — not 100%," he says. "You might have a mild case of COVID-19,but you can still spread it to others, including those who are immune compromised, such as cancer patients. That's why we continue to wear masks until we get very widespread immunization." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about breakthrough infections and the Johnson & Johnson COVID-19 vaccine pause, and he answers listeners' questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 22, 2021
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Mayo Clinic Q&A: On the Verge of Another COVID-19 Surge

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    As spring break travelers return home and the highly transmissible U.K. COVID-19 variant is discovered in all 50 U.S. states, the country is on the verge of a fourth COVID-19 pandemic surge. That's according to a number of health experts, including Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.   However, Dr. Poland says there is some good news related to the transmission of COVID-19 on surfaces.  "Wisdom resides in changing your mind and your recommendations as new data and science becomes available," says Dr. Poland. "What the Centers for Disease Control and Prevention is doing is modifying those guidelines, saying that the risk of touching a contaminated surface and then getting infected is very low." In this Mayo Clinic Q&A podcast Dr. Poland explains more about the CDC guidelines and he addresses other COVID-19 topics in the news, including recent data that says men are more vaccine-hesitant than women. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 21, 2021
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Utilizing Artificial Intelligence to Evaluate Dizziness

Guest: Devin L. McCaslin, Ph.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Being dizzy means different things to different patients and most patients find dizziness difficult to describe. Providers find it difficult to evaluate patients with dizziness and also which specialties can be asked for help in managing the dizzy patient. Dr. Devin McCaslin is the Director of the Vestibular and Balance Laboratory at the Mayo Clinic and an expert in evaluating the dizzy patient. He will discuss such topics as the role of vestibular balance laboratory testing in assessing patients, the most common findings from these evaluations, the multi-disciplinary approach to evaluating patients with dizziness, and how artificial intelligence is being used in the evaluation of a patient complaining of dizziness. Specific Topics Discussed: The multi-disciplinary approach to evaluating patients complaining of dizziness. Most common findings in the evaluation of a patient with dizziness. The role of vestibular balance laboratory testing in assessing patients who are candidates for these tests. How artificial intelligence is being used in the evaluation of patients with dizziness. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 20, 2021
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Mayo Clinic Q&A: Vacation Travel, Vaccines for Teens and More COVID-19 News

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    If you're fully vaccinated for COVID-19 you can travel domestically and where travel is allowed internationally, according to new interim travel guidelines from the Centers for Disease Control and Prevention (CDC). Even with those recommendations the CDC continues to recommend not traveling unless it is essential. Regardless, the CDC strongly recommends people continue to wear a face mask, practice social distancing and sanitize their hands. Meanwhile, COVID-19 vaccine research is continuing in teenagers. "The early data show equal safety in young people aged 12 to 16," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "I think this is going to imply that, somewhere between this fall and Christmas, we're going to be able to offer the (COVID-19) vaccine to every age group." In this Mayo Clinic Q&A podcast, Dr. Poland answers a number of listener questions, including how long the COVID-19 vaccines are predicted to last and if the current transmission research still supports wiping down household items. Dr. Poland also explains why someone who has had COVID-19 should still get a COVID-19 vaccine. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 19, 2021
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This Podcast Will Make Your Head Spin

Guest: Scott D. Eggers, M.D. (@sdze) Host: Darryl S. Chutka, M.D. (@ChutkaMD)  The complaint of dizziness is a common symptom our patients experience. It has a variety of causes; fortunately, most of them are benign. Despite the fact we frequently see patients with this medical concern, we still struggle evaluating them. Part of the difficulty is that dizziness means different things to different people and the cause of dizziness can be caused by disorders in one of several organ systems. To help us evaluate dizziness, Dr. Scott Eggers, a neurologist at the Mayo Clinic, reviews why dizziness is so difficult to evaluate and how we should evaluate a patient who complains of dizziness. We also explore the most common causes of dizziness including benign positional vertigo and vestibular neuritis. Finally, Dr. Eggers reviews symptoms that are suspicious for an ominous cause of dizziness. Specific topics discussed: Why dizziness is difficult to evaluate How to evaluate the complaint of dizziness Most common causes of dizziness Dizziness symptoms which are ominous for serious disease Description of benign positional vertigo Description of vestibular neuritis Description of vestibular migraines Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 13, 2021
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COVID-19 Miniseries Episode 69: Post-Acute COVID-19 and Central Sensitization

Central sensitization (CS) describes pathophysiologic changes in the central nervous system, including alterations in neurochemistry, CNS receptors, endogenous opioid system hyperactivity, cytokine and HPA axis dysregulation, and sympathetic hyperactivity. Collectively, these changes result in amplification of pain and sensory signals, leading to widespread pain, fatigue and other sensory sensitivities. Fibromyalgia and Chronic Fatigue Syndrome are established diagnoses/manifestations of central sensitization. In the era of the COVID-19 pandemic, we continue to learn about Post-Acute COVID-19 Syndrome, a manifestation of central sensitization similar to other post-infectious forms of CS, which underlies the persistent symptoms that many people experience after initial recovery from COVID-19. Elizabeth C. Wight, M.D. joins us to talk about Mayo Clinic’s treatment approach to central sensitization, which is rooted in empowering patients with education and a framework for a self-management program. This includes stress management, moderation, positive thinking, decreasing focus on symptoms, sleep hygiene, and Cognitive Behavioral Therapy among others. Additional resources: Post-COVID Recovery on Mayo Clinic Connect: https://connect.mayoclinic.org/page/post-covid-recovery/ Mayo Clinic’s “A Systematic Approach to Medically Unexplained Symptoms 2021” course can be found at https://ce.mayo.edu/internal-medicine/content/systematic-approach-medically-unexplained-symptoms-2021#group-tabs-node-course-default1 Clauw DJ. Fibromyalgia: A clinical review. JAMA. 2014;311(15):1547-1555. doi:1001/jama.2014.3266 Clauw DJ. Fibromyalgia and related conditions. Mayo Clin Proc. 2015 May;90(5):680-92. https://doi.org/10.1016/j.mayocp.2015.03.014 Harte, SE, Harris, RE, Clauw, DJ. The neurobiology of central sensitization. J Appl Behav Res. 2018; 23(2): e12137. https://doi.org/10.1111/jabr.12137 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 6, 2021
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Your Patient Has a Thyroid Nodule – What Now?

Guest: Jan L. Kasperbauer, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Thyroid nodules are commonly found in patients by primary care providers, either by physical exam or incidentally by a variety of imaging studies. Fortunately, the vast majority of thyroid nodules are benign, however as primary care providers we need to be comfortable in evaluating them to rule out the possibility that they represent a thyroid cancer. Joining us is Dr. Jan Kasperbauer, an otolaryngologist at the Mayo Clinic. We discuss risk factors for thyroid cancer, how a primary care provider should evaluate and manage patients with thyroid nodules, various types of thyroid cancer, and treatment options as well as the recommended follow-up for patients with thyroid cancer. Specific topics discussed: Risk factors for thyroid cancer Detecting thyroid cancers How primary care provider should evaluate and manage patients with thyroid nodules Review of the various types of thyroid cancer Treatment options for thyroid cancer Recommendations for primary care providers in following patients with treated thyroid cancer Additional resources: Classification for risk stratification and follow up recommendations: Grant, EG, et al. Thyroid ultrasound reporting lexicon: white paper of the ACR thyroid imaging, reporting and data system (TIRADS) committee. J Am Coll Radiol. 2015 Dec; 12(12): 1272-1279. doi: https://doi.org/10.1016/j.jacr.2015.07.011 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 30, 2021
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Mayo Clinic Q&A: Viruses Cannot Mutate If They Cannot Replicate

This episode is shared from Mayo Clinic Q&A and was recorded in March, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  The COVID-19 virus mutates and replicates when people let down their guard and don't follow safety protocols, such as practicing social distancing and wearing a mask.  "I think most of us expect a major surge because of spring break travel and the relaxation of restrictions," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And the sort of COVID fatigue that all of us feel, in one way or another." In this Mayo Clinic Q&A podcast, Dr. Poland addresses the potential of a fourth COVID-19 surge, new information regarding the COVID-19 vaccines for pregnant women and he discusses research for next generation vaccines for COVID-19 variants. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 26, 2021
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COVID-19 Miniseries Episode 68: Skin Integrity in Patients with COVID-19

Guest: Jennifer L. Elmer, APRN, CNS, D.N.P.; Brianna M. Skrukrud, APRN, C.N.P. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Pressure injuries in bedridden patients present significant challenges​, which are compounded in the patient with a COVID-19 diagnosis. In this episode we discuss the problems encountered in preventing, diagnosing, and managing skin alterations in patients with COVID-19. Jennifer L. Elmer, APRN, CNS, D.N.P. and Brianna M. Skrukrud, APRN, C.N.P., two wound care experts at Mayo Clinic, discuss situations ​in which, despite best efforts, pressure injuries are unavoidable and why COVID-19 poses a great risk for skin alterations in hospitalized patients. They also discuss the 2020 position statement of National Pressure Injury Advisory Panel (NPIAP) on the management of skin alterations during the COVID-19 crisis. Additional resources: Unavoidable Pressure Injury during COVID-19 Pandemic: A Position Paper from the National Pressure Injury Advisory Panel https://cdn.ymaws.com/npiap.com/resource/resmgr/white_papers/Unavoidable_in_COVID_Pandemi.pdf Skin Manifestations with COVID-19: The Purple Skin and Toes that you are seeing may not be Deep Tissue Pressure Injury https://cdn.ymaws.com/npiap.com/resource/resmgr/white_papers/COVID_Skin_Manifestations_An.pdf Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 23, 2021
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Mayo Clinic Q&A: Rapid Pace of COVID-19 Vaccinations

This episode is shared from Mayo Clinic Q&A and was recorded in March 2021.  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: DeeDee Stiepan (@deedeestiepan)  Millions of people in the U.S. are being vaccinated for COVID-19. However, discussion is ongoing as to whether people who are immunocompromised, such as patients undergoing cancer treatment, or people who have autoimmune diseases, should be vaccinated for COVID-19.  "Both of those categories (of people) should be vaccinated," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Those are not contraindications. Those are indications to get the vaccine." He adds that research is ongoing, but current information demonstrates the benefits far outweigh the theoretical risks.  In this Mayo Clinic Q&A podcast, Dr. Poland talks about vaccine hesitancy, and patients who are immunocompromised or have autoimmune conditions. Also, he discusses next steps in the journey to vaccinate children for COVID-19. And he reviews recent guidance from the Centers for Disease Control and Prevention Control about in-person gatherings.  AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 19, 2021
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Can We Prevent Suicide?

* WARNING: This episode discusses suicide and suicidal ideation. * Guest: J. Michael Bostwick, M.D.(@DrBostwick) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) In this episode, professor of psychiatry and international authority on suicide risk and challenges in suicide prevention, J. Michael Bostwick, M.D.  from Mayo Clinic in Rochester joins us. He’ll discuss epidemiological-based research looking at the utilization patterns of medical care by individuals who have contemplated or committed suicide. Dr. Bostwick will describe the concept of suicide crisis including risk factors, current events/warning signs, and mental status/agitation. He’ll also explain self-agency, stigma of discussing mental illness, potential value-based societal approach to individuals in distress and despair, and potential solutions to the suicide prevention. Additional resources: Suicide Prevention in Primary Care Medicine; Huguet, Nathalie et al.; Mayo Clinic Proceedings, Volume 90, Issue 11, 1459 – 1461; https://doi.org/10.1016/j.mayocp.2015.09.011 Grappling With Suicide Risk; Sublette, M. Elizabeth; Mayo Clinic Proceedings, Volume 93, Issue 6, 682 – 683; https://doi.org/10.1016/j.mayocp.2018.04.006 Suicide Attempt as a Risk Factor for Completed Suicide: Even More Lethal Than We Knew; Bostwick, J. Michael et al.; Amer Journal of Psychiatry; Volume 173, Issue 11, November 01, 2016, 1094-1100; https://doi.org/10.1176/appi.ajp.2016.15070854 If you're feeling overwhelmed by thoughts of not wanting to live or you're having urges to attempt suicide, get help now. Call 911 or your local emergency number immediately. Call a suicide hotline. In the U.S., call the National Suicide Prevention Lifeline at 1-800-273-8255 any time of day — press "1" to reach the Veterans Crisis Line or use Lifeline Chat. For a list of suicide hotline numbers outside of the U.S., visit: https://www.opencounseling.com/suicide-hotlines Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 18, 2021
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Mayo Clinic Q&A: “Brain Fog” is a Lingering Condition for Many COVID-19 Long-Haulers

This episode is shared from Mayo Clinic Q&A and was recorded in March, 2021.  Guest:  Billie A. Schultz, M.D.  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)  Fatigue and what's being called "brain fog" are turning out to be some of the most common issues for long-hauler patients recovering from COVID-19. The National Institutes of Health calls these and other symptoms, which can last for several months, post-acute sequelae of SARS-CoV-2, or PASC. Those suffering from brain fog may experience short-term memory loss, confusion, difficulty concentrating, or just feeling different than they did before they had COVID-19, even if it was a mild case of the infection.  And Dr. Billie Schultz, a Mayo Clinic physical medicine and rehabilitation expert, says, though older patients more often to have these symptoms more often, younger people are also showing up with brain fog. In this Mayo Clinic Q&A podcast, Dr. Schultz says brain fog seems to be more inflammatory than infection, but there are more questions than answers about this neurological concern. Meanwhile, efforts are underway to develop rehabilitation programs to help patients recover. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 17, 2021
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COVID-19 Miniseries Episode 67: Finding a Solution for Every Long-Hauler

Guest: Ravindra Ganesh, M.B.B.S., M.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) It has been estimated that as many as 10-30% of patients who have recovered from COVID-19 have an array of symptoms, ranging from minor to disabling, that persist more than four weeks post-COVID infection. These symptoms have not only been identified in patients who had severe symptoms of COVID-19 requiring intensive care unit treatment, but also those who only experienced mild-to-moderate symptoms. The exact cause of this state, most popularly called post-COVID long hauler syndrome, is still under investigation. The symptoms range from mild to disabling fatigue, body aches, atypical chest pain, loss of sense of taste and smell, brain fog, among others and many of these patients need additional evaluation and management to deal with their disabling symptoms. In this podcast Dr. Ravindra Ganesh, the consultant in General Internal Medicine who leads the COVID Frontline Care Team (CFCT) efforts, as well as the Post-COVID Clinic, at Mayo Clinic Rochester, discusses the array of symptoms, management strategies, and research possibilities, as well as opening of an upcoming clinic in Mayo Clinic Rochester that would address the concern of the patient's and deal with the post COVID long hauler symptoms Additional Resources: Post-COVID Syndrome on Ask Mayo Expert: https://askmayoexpert.mayoclinic.org/  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 16, 2021
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Clostridium Difficile Infection: You Want to Transplant What?!

Guest: Maria I. Vazquez Roque, M.D. (@MVazquezRoqueMD)  Host: Darryl S. Chutka, M.D. (@ChutkaMD)  Clostridium difficile is a toxin-producing bacterium that can result in a severe form of antibiotic-associated diarrhea known as clostridium difficile infection or CDI. Cases can vary from mild diarrhea to severe colitis that at times can be fatal. There’s been a dramatic increase in the number as well as severity of CDIs in the U.S. over the past 20 years. Although CDI typically occurs following the use of antibiotics, it can also be spread from one individual to another, especially in hospitals and skilled nursing facilities. Antibiotics have been the traditional treatment for patients with CDI, however recurrent symptoms have been a problem. There’s now a new treatment for CDI, felt to be effective in over 90% of patients with the illness. Our guest to discuss this topic is Dr. Maria Vazquez Roque, a gastroenterologist at the Mayo Clinic. We’ll review the common presenting symptoms, laboratory tests needed to establish a diagnosis, and the current recommendations for treatment including the latest of fecal transplantation.  Additional resources:  Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): https://doi.org/10.1093/cid/cix1085  Specific topics discussed: The typical presentation of C. difficile infection Patients who are at increased risk for a C. difficile infection Laboratory tests to order to confirm a case of C. difficile infection Treatment options for C. difficile infection including fecal transplantation Potential benefit of probiotics for preventing a C. difficile infection Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 9, 2021
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Mayo Q & A: COVID-19 Variants and the Evolving Science

This episode is shared from Mayo Clinic Q&A and was recorded in February, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    People may be curious, confused or critical of what seem to be changing messages related to the COVID-19 pandemic. Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, reminds folks that messages change because data changes and the science evolves. "As we learn new science, we use that science to modify our recommendations," says Dr. Poland. "It's not that scientists are flip-flopping. It is that new data allows us to begin expanding those recommendations." For instance, COVID-19 cases and deaths in the U.S. are currently declining. But, Dr. Poland says, there are new data predicting the possibility of another surge of COVID-19 infections in March because of U.K. variant transmission. In this Mayo Clinic Q&A podcast Dr. Poland talks about several issues, including the U.K. variant, vaccine development and the public’s COVID-19 fatigue. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 3, 2021
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COVID-19 Miniseries Episode 66: Monoclonal Antibody Treatment for COVID-19

Guest: Ravindra Ganesh, M.B.B.S., M.D. and Raymund R. Razonable, M.D.  Host: Amit K. Ghosh, M.D. (@AmitGhosh006)  In this episode, Ravindra Ganesh, M.B.B.S., M.D. and Raymund R. Razonable, M.D. join Amit K. Ghosh, M.D. to review the use of monoclonal antibody as a new antiviral agent in the treatment of COVID-19 infection.  Who is most likely to benefit from monoclonal antibody infusions? Drs. Ganesh and Razonable, discuss recent studies on monoclonal antibody infusions in patients with mild to moderate COVID-19 infections. Also discussed are the logistical challenges faced and the innovative solutions that were implemented while administering this therapy, particularly navigating the acceptance of treatment, its real and perceived side effects, and lack of awareness due to inequity and poverty. Research on the development of subcutaneous or intramuscular administration for prophylaxis against COVID-19 in patients at high risk for complications or at high risk for being exposed to SARS-CoV-2 is also discussed in this episode.  Additional resources:  AskMayoExpert COVID-19 Navigator: https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Weinreich DM, Sivapalasingam S, Norton T, et al. REGN-COV2, a neutralizing antibody cocktail, in outpatients with Covid-19. N Engl J Med 2021;384:238-251.  Chen P, Nirula A, Heller B, et al. SARS-CoV-2 neutralizing antibody LY-CoV555 in outpatients with Covid-19. N Engl J Med 2021;384:229-237.  Gottlieb RL, Nirula A, Chen P, et al. Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial.JAMA. Published online January 21, 2021. doi:10.1001/jama.2021.0202  An EUA for Bamlanivimab—A Monoclonal Antibody for COVID-19. JAMA. Published online December 11, 2020. doi:10.1001/jama.2020.24415  Monoclonal Antibodies: Update on this COVID-19 Experimental Therapy  https://discoverysedge.mayo.edu/2021/02/17/monoclonal-antibodies-update-on-this-covid-19-experimental-therapy/  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 2, 2021
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COVID-19 Miniseries Episode 65: Restoring Function for Long-Haulers

Guest: Greg Vanichkachorn, M.D., M.P.H.Host: Amit K. Ghosh, M.D. (@AmitGhosh006)For some patients who have had COVID-19, symptoms of the disease may last long after the infection is over. Long-haulers syndrome due to COVID-19 could include profound fatigue, shortness of breath, and long-term neurological complaints, including headache, dizziness, or weakness. Mayo Clinic has launched the COVID Activity Rehabilitation Program, or CARP, to help these patients return to daily life and work. CARP is not just for folks who are trying to get back to work, but for anyone trying to get back to their baseline life.In this episode, Dr. Greg Vanichkachorn, a Mayo Clinic preventive, occupational and aerospace medicine specialist who leads the CARP program, gives an overview of COVID long haulers and how post-COVID symptoms affects patients. He also shares the goals and results of Mayo Clinic CARP program.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 16, 2021
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Answers From the Lab: The Impact of COVID-19 Variants

This episode is shared from Answers from the Lab and was originally published February 2, 2021. Guest: Matthew J. Binnicker, Ph.D. (@DrMattBinnicker)Host: William G. Morice, II M.D., Ph.D. (@moricemdphd)Matthew Binnicker, Ph.D., vice chair of practice for Mayo Clinic's Department of Laboratory Medicine and Pathology, joins William Morice II, M.D., Ph.D., president of Mayo Clinic Laboratories, for this week's "Answers From the Lab" leadership update. In this episode, Dr. Binnicker and Dr. Morice discuss the impact that emerging COVID-19 variants could have on virus testing, vaccine and spread.For more, follow the Mayo Clinic Labs on Twitter @mayocliniclabs or visit https://news.mayocliniclabs.com/podcast/answers-from-the-lab/ to check out all of their episodes.
February 9, 2021
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COVID-19 Miniseries Episode 64: Leveraging Community Care for Scalable Outpatient Management of COVID-19

Guest: Ravindra Ganesh, M.B.B.S., M.D.Host: Amit K. Ghosh, M.D. (@AmitGhosh006)The Mayo Clinic COVID Frontline Healthcare Team (CFCT) is an integrated team comprised of doctors and support staff, including nurses, remote monitoring technicians, medical assistants, and desk staff. These teams are responsible for evidence-based management of all newly diagnosed COVID-19 patients. We’re joined by CFCT Codirector Ravindra Ganesh, M.B.B.S., M.D., to discuss the essential roles of CFCT’s during the pandemic.Topics include how they:Notify all patients who receive a COVID positive test result in Mayo/Mayo Clinic Health service in the Midwest region through phone call or portal messaging with attached questionnaireConduct outpatient monitoring and follow-up as well as identify patient at high risk for decompensationPrevent COVID positive patients from coming to the Mayo Clinic facilities by remote monitoring and risk assessmentReinforce social isolation recommendations from public health to all COVID positive patients and assess safety to come off isolationConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 9, 2021
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COVID-19 Miniseries Episode 63: Mayo Clinic Q&A – #AskTheMayoMom about Sports Participation During COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in February, 2021To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  David B. Soma, M.D. (@DrDaveSoma); Talha Niaz, M.B.B.S.Host: Angela C. Mattke, M.D. (@DrAngelaMattke)There are many benefits to sports participation for children and adolescents. However, during the COVID-19 pandemic, activities such as youth sports have been put on hold or modified to decrease the spread of COVID-19. Also, the scientific community is learning about when it is safe to return to sports participation following COVID-19 infection.  On the Mayo Clinic Q&A podcast, "Ask the Mayo Mom" host and Mayo Clinic pediatrician, Dr. Angela Mattke is joined by Dr. David Soma, a pediatric sports medicine physician at Mayo Clinic Children's Center, to discuss sports participation during the COVID-19 pandemic and what you need to know about return to play after COVID-19 infection. Also joining Drs. Mattke and Soma is Dr. Talha Niaz, a pediatric cardiologist at Mayo Clinic. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
February 8, 2021
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COVID-19 Miniseries Episode 62: Mayo Clinic Q&A: COVID-19 Virus, Variants and Vaccines Update

This episode is shared from Mayo Clinic Q&A and was recorded in February, 2021To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@DrGregPoland)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)   When it comes to the COVID-19 pandemic, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, says there's some good news. "Case numbers are falling, masking and distancing do work, and we can control this if we do it right."  However, the not so good news is that variants are showing up in over 30 countries and are reportedly more transmissible. There also seems to be a reduction in vaccine efficacy against the new variants. "This is a desperate race between vaccine and virus, between time and opportunity, and we dare not lose that opportunity," emphasizes Dr. Poland. In this Mayo Clinic Q&A podcast, Dr. Poland discusses how COVID-19 viruses mutate into new variants. He also discusses recent COVID-19 research conducted by the NFL, plus he touches on the future of individualized vaccines. "I can see the development of a coronavirus vaccine against multiple types of coronavirus, including the one that causes the common cold, and very likely combine that with the influenza vaccine."AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 4, 2021
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COVID-19 Miniseries Episode 61: Mayo Clinic Q&A: Picking Up the Pace With Rollout of COVID-19 Vaccines

This episode is shared from Mayo Clinic Q&A and was recorded in January, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The distribution kinks for COVID-19 vaccines are getting ironed out, says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group."It's a logistics nightmare, but now you're seeing a plan to administer 1 million doses a day and I think that's very achievable," says Dr. Poland. "And the production of the vaccine is just going to accelerate."Dr. Poland also repeats the reminders about preventing transmission of COVID-19:Wear a mask.Wash your hands.Keep your social distance. "The current estimates are that in the next four weeks, we'll probably have about another 100,000 deaths," adds Dr. Poland. "It's stunning when you think about 1 out of every 860 Americans has now died of this."In this Mayo Clinic Q&A podcast, Dr. Poland talks more about the rollout, transmission and herd immunity, as well as fertility issues related to COVID-19, survivor brain fog and more.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
February 4, 2021
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Want to Know About Pediatric Enuresis? Well, Urine Luck

Guest: Patricio Gargollo, M.D. (@pgargollo)Host: Darryl S. Chutka, M.D. (@ChutkaMD)Enuresis is relatively common in children, estimated to be present in as many as 5 to 10% of 7-year-olds. This represents up to 7 million children in the United States. As you can imagine, it carries significant social implications for the child. Our guest for this podcast is Dr. Patricio Gargollo, a pediatric urologist at Mayo Clinic in Rochester, Minnesota. Dr. Gargollo will address the natural history of enuresis, how to evaluate the child with enuresis, how often it represents a structural urologic problem and how often a treatable cause is found. Practical advice for parents of children with enuresis is also discussed.Specific topics:Potential for children with enuresis to have bladder control problems when they develop into adulthood.Social impact of enuresis on a child.Potential risk factors and causes of enuresis.The role of genetics and enuresis.The natural history of enuresis.How often a structural urologic problem is found to explain enuresis.Pharmacologic treatment options.The evaluation of a child with enuresis.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
February 2, 2021
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Answers From the Lab: National COVID-19 Strategy

This episode is shared from Answers from the Lab and was originally published January 28, 2021. Guest: William G. Morice, II M.D., Ph.D. (@moricemdphd) Host: Bobbi S. Pritt, M.D. (@ParasiteGal) William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the new nationwide strategy that the Biden administration is rolling out to combat COVID-19.
January 28, 2021
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COVID-19 Miniseries Episode 60: Restoring Joy to Healthcare

Guest: Eric J. Cleveland; Danielle M. Teal (@dteal)Host: Amit K. Ghosh, M.D. (@AmitGhosh006)Joy has been defined as a human emotion — a state created as we experience positive, poignant, reflective and connective moments. It is transient, never persisting but imparting ripples that impact us long after the moment.Now more than ever there is a need to develop mindful initiatives that brings joy in our personal lives and in the workplace. In this episode we speak with Eric Cleveland and Danielle Teal, two leaders of the Joy at Mayo Clinic ([email protected]) initiative. We will discuss the joy equation, the Institute of Health Improvement’s (IHI) Framework for Improving Joy in Work and discuss examples of pragmatic initiatives that can bring joy at both the individual and team levels.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 26, 2021
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COVID-19 Miniseries Episode 59: Mayo Clinic Q&A – Expert Updates on COVID-19 Vaccines

This episode is shared from Mayo Clinic Q&A and was recorded on January 11, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The U.S. rollout of COVID-19 vaccines is reportedly ramping up with news that nearly all available doses will soon be released to the American public. "The new COVID-19 variants are traveling quickly, and this is a warning that we need to take precautions," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. Dr. Poland says these new variants are a consequence of an RNA virus being transmitted from human to human. "Even after we get our vaccines, we still need to wear masks out in public. We still need to maintain physical distancing. And we still need to wash our hands until about 80% of people get their COVID-19 vaccines," Dr. Poland emphasizes.In this Mayo Clinic Q&A podcast, Dr. Poland goes into detail about the COVID-19 vaccines, including "sterilizing immunity," testing for antibodies after receiving the vaccine, the possibility of booster doses in the future and much more. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 21, 2021
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Adult Eating Disorders

Guest: Leslie A. Sim, Ph.D., L.P. (@DrLeslieSim)Host: Darryl S. Chutka, M.D. (@ChutkaMD)A variety of eating disorders can occur in adults and they are associated with multiple potential health complications, including an increased risk of death. Some studies report that up to 20% of those with Anorexia Nervosa will die as a result of the condition. Would you recognize an eating disorder in the patients you see? What clues should you look for? In this week’s Mayo Clinic Talks, we’ll speak with Dr. Leslie Sim, a psychologist at the Mayo Clinic. We’ll discuss who is most likely to develop an eating disorder, important “red flag” symptoms, questions you should ask patients to help confirm a diagnosis, and how we should approach a patient we suspect has an eating disorder.Topics discussed:Definition of an eating disorderImportant “red flag” symptoms that may indicate an eating disorderHealth complications that can occur as a result of an eating disorderWho is most likely to have an eating disorderThe genetic component to eating disordersClues from their childhood that suggest patients may have an eating disorder as an adultEvents which can trigger an eating disorderWhen we should suspect an eating disorderHow we should approach a patient we suspect has an eating disorderManagement of eating disordersEffectiveness of treatmentConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 19, 2021
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COVID-19 Miniseries Episode 58: Mayo Clinic Q&A – #AskTheMayoMom about COVID-19 and School Children

This episode is shared from Mayo Clinic Q&A and was recorded in January, 2021.Guests: Emily R. Levy, M.D. (@EmilyLevy797); Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD)Host: Angela C. Mattke, M.D. (@DrAngelaMattke)Around the world, COVID-19 vaccinations are underway, but only in adults. Pfizer's vaccine has been authorized for ages 16 and up, while Moderna's vaccine is currently authorized for ages 18 and up. Vaccines are generally tested in adults first to ensure they are safe for pediatric trials. Both Pfizer and Moderna now have clinical trials underway to study the safety and effectiveness of COVID-19 vaccines in children. This edition of the Mayo Clinic Q&A podcast features an #AskMayoMom episode hosted by Dr. Angela Mattke, a pediatrician at Mayo Clinic Children's Center. Joining Dr. Mattke to discuss COVID-19, vaccines and children are Dr. Nipunie Rajapakse, a Mayo Clinic pediatric infectious diseases physician, and  Dr. Emily Levy, a Mayo Clinic pediatric critical care and infectious diseases expert. Dr. Levy also discusses multisystem inflammatory syndrome in children, also known as MIS-C.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 14, 2021
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Motion is Lotion: Staying Healthy While Working Remote

Guest: Corey M. Kunzer, P.T., D.P.T., SCS, (@KunzerCorey) and Edward R. Laskowski, M.D. (@DrEdSportsMed)Host: Darryl S. Chutka, M.D. (@ChutkaMD) Over the past decade more individuals have begun working remotely; the numbers have increased dramatically this past year with the COVID-19 pandemic. While there are some advantages to working remotely, there are also some potential problems associated with it. Those working from home often develop a variety of musculoskeletal problems including low back and neck pain, as well as shoulder and extremity discomfort. Drs. Edward Laskowski, a physician and Corey Kunzer, a physical therapist, both in the Department of Physical Medicine and Rehabilitation at the Mayo Clinic will discuss some of the musculoskeletal problems associated with working remotely.Specific topics discussed:Frequency of musculoskeletal problems associated with working from homeDifferences between working at home vs. the traditional officeIssues to consider when selecting a desk and chairRecommended positions of the monitor, keyboard and mouseBenefits of a standing workstation or working while walking on a treadmillConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 12, 2021
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Can Nutritional Supplements Turn You into an All-Star?

Guest: Andrew Jagim, Ph.D. (@AJagim)Host: Darryl S. Chutka, M.D. (@ChutkaMD) Billions of dollars per year are spent in the U.S. on nutritional supplements to enhance performance. Multiple nutritional supplements are commercially available and are marketed for enhancing endurance, building muscle strength, improving exercise efficiency, and decreasing the potential for injury. Do these supplements actually deliver the benefits they claim? Are they safe? What age athletes are taking these supplements?  We’ll discuss these topics and more with Dr. Andrew Jagim, the director of sports medicine research at the Mayo Clinic.Specific topics:Recommended approach to the athlete who wants to improve their performancePotential benefits of nutritional supplements for athlete'sAge of athletes taking nutritional supplementsSelecting a high-quality nutritional supplementReliable web sites reviewing the available nutritional supplements including potential benefits and safetyReview of commonly taken nutritional supplementsNutritional supplements which have potential harmAdditional Resources:Mayo Clinic Proceedings Article: https://www.mayoclinicproceedings.org/article/S0025-6196(20)30363-3/fulltextNIH – Office of Dietary Supplements: https://ods.od.nih.gov/factsheets/ExerciseAndAthleticPerformance-HealthProfessional/International Society of Sports Nutrition (ISSN): https://www.sportsnutritionsociety.org/Third-Party Testing Information: https://examine.com/Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
January 5, 2021
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Mayo Clinic Q&A: Opioid Crisis Worsens During COVID-19 Pandemic

This episode is shared from Mayo Clinic Q&A and was recorded in December, 2020. Guest: Tyler Oesterle, M.D., M.P.H. (@OesterleMD) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Stress, isolation and limited access to resources are fueling rising rates of substance abuse and overdoses during the COVID-19 pandemic. While coronavirus has been the focus of so much attention this year, the opioid crisis has continued unabated and has even worsened. More than 40 states have reported increases in opioid related deaths, according to the American Medical Association. On the Mayo Clinic Q&A podcast, Dr. Tyler Oesterle, a psychiatrist and addiction expert at Mayo Clinic, discusses opioid use disorders and treatment options, including virtual medicine available during the pandemic. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 4, 2021
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Mayo Clinic Q&A: COVID-19 Mortality Study Shows Effectiveness of Team-Based Care

This episode is shared from Mayo Clinic Q&A and was recorded in December, 2020. Guest: John (Jack) C. O'Horo, M.D., M.P.H. (@jcohoro) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) A recent Mayo Clinic study published in Mayo Clinic Proceedingsfound that patients with COVID-19 who received care at Mayo Clinic had lower mortality rates than the national average. Mayo Clinic patients were treated using an integrated, team-based approach for patient monitoring and treatment. On the Mayo Clinic Q&A podcast, Dr. John O'Horo, a Mayo Clinic infectious diseases physician and the study's first author, discusses the study results and explains how the Mayo Clinic Model of Care improves outcomes for patients. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
January 1, 2021
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Addressing the Burdens of Family Caregivers

Guest: Alisha Morgan, D.O. (@AAMORGAN_DO)Host: Darryl S. Chutka, M.D. (@ChutkaMD)It’s estimated that there may be over 30 million individuals in the U.S. who provide ongoing care to older adults, half of these to family members with some form of dementia. The majority of these caregivers are female and a significant percentage of these caregivers have their own major health problems. This has become a major social and economic issue in the care of our geriatric patients. Dr. Alisha Morgan, a family medicine and hospice physician at the Mayo Clinic joins us to address the challenges associated with being a caregiver, how healthcare providers should assess caregiver burden, potential financial resources available to assist caregivers, and interventions to reduce the impact of stress on caregivers.Specific topics:Morbidity and mortality of care giversThe amount of time caregivers devote to assisting older adultsFinancial burden of providing chronic care to older adultsHow primary care providers should acknowledge caregiversHow primary care providers should evaluateHow caregiver stress should be providedAvailable financial resources for caregiversCaregiver Resources: https://www.aarp.org/content/dam/aarp/entertainment/books/2015-04/Caregivers_Excerpt.pdfConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 29, 2020
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COVID-19 Miniseries Episode 57: Transcending the Valley of Death – COVID-19 mRNA Vaccine Update

This episode was recorded on December 18, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) It is projected that by March of 2021 1:700 Americans will have died of COVID-19. The historic pace of COVID-19 vaccine development was made possible by the countless sacrifices of many individuals across healthcare, research, health and human services, the Department of Defense, and other key sectors. This interprofessional collaboration required many to set life aside and work tirelessly to bring an effective vaccine to market, quickly. While mRNA vaccines have been in development since the 1990s, the COVID-19 vaccine efficacy rate of 95-100% across studied ages, race and ethnicities, and comorbidities is unprecedented. The questions left to answer are, how long will the efficacy last? In larger population studies, what is the safety/allergy/hypersensitivity profile? What impact does the vaccine have on asymptomatic carrier spread? Who shouldn’t get the vaccine? Dr. Greg Poland breaks down everything you need to know about the mRNA COVID-19 vaccines. Additional Resources:Mayo Clinic Vaccine Research Page https://www.mayo.edu/research/labs/vaccine-research-group/overview Vaccine education spectrum disorder: the importance of incorporating psychological and cognitive models into vaccine education https://www.sciencedirect.com/science/article/pii/S0264410X11011881 AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
December 21, 2020
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Sensorineural Hearing Loss

Guest: Matthew L. Carlson, M.D. (@MatthewLCarlso1)Host: Darryl S. Chutka, M.D. (@ChutkaMD) Issues surrounding hearing loss are discussed with Dr. Matthew Carlson, an ENT physician from the Mayo Clinic. Specific topics discussed include the following:Types of hearing loss (conductive vs. sensorineural)Social impact of hearing lossSymptoms patients notice with gradually progressive hearing lossTinnitus and it’s managementCauses of sensorineural hearing lossHigh frequency tone loss and problems with speech discrimination associated with sensorineural hearing lossHearing loss associated with loud noise exposure (acoustic injury and chronic noise exposure)Hearing loss associated with the use of firearmsCommon everyday activities which may result in hearing lossManagement of sensorineural hearing loss (hearing aids, cochlear implants)Recent advances and improvements in hearing aidsConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 15, 2020
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Immunizations: Let’s Get to the Point

This episode was recorded on October 23, 2020.Guest: Robert M. Jacobson, M.D. (@RobertJMD)Host: Darryl S. Chutka, M.D. (@ChutkaMD)It’s estimated that immunizations have saved more lives and prevented more disabilities than any other medical intervention. They’re also extremely cost effective and their benefits far outweigh the very small risks they carry. Yet there are individuals who choose to believe that immunizations are potentially harmful. Our guest for this podcast is Dr. Robert Jacobson, a Mayo Clinic pediatrician and expert in the field of immunizations. We cover topics including an update on the COVID-19 vaccine and when it will realistically be available on a large scale for the population. Other important issues discussed include which vaccines are important for children and adults and whether it’s safe to administer multiple vaccines at one time. Finally, many of the concern promoted by the anti-vaccine movement are discussed and dispelled.Specific topics discussed:Variety of vaccines in development for COVID-19Novel techniques being use in the development of the COVID-19 vaccineTiming on the availability of the COVID-19 vaccineImportant immunizations for childrenImportant immunizations for adultsAnti-vaccine concerns and myths surrounding vaccinesUpdates on the age recommendations for the HPV vaccineConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 8, 2020
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COVID-19 Miniseries Episode 56: Mayo Clinic Q&A – How Messenger RNA Vaccines Work

This episode is shared from Mayo Clinic Q&A and was recorded in December, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The first COVID-19 vaccines to reach the market are likely to be messenger RNA vaccines, or mRNA. According to the Centers for Disease Control and Prevention, mRNA vaccines work by teaching cells in the body how to make a protein that triggers an immune response. Unlike many vaccines that use a weakened or inactivated form of a virus, mRNA vaccines do not use the live virus that causes COVID-19. On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, explains how mRNA vaccines work, gives a status update on the pandemic and answers listener questions.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
December 3, 2020
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COVID-19 Miniseries Episode 55: Mayo Clinic Q&A – Managing the COVID-19 Surge

This episode is shared from Mayo Clinic Q&A and was recorded in November, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Elie F. Berbari, M.D. Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)The current COVID-19 surge numbers could worsen in coming days as experts prepare for a post-Thanksgiving holiday increase in cases. Increased positivity rates lead to more people needing hospitalization, straining the health care system and medical staff.On the Mayo Clinic Q&A podcast, Dr. Elie Berbari, chair of the Division of Infectious Diseases at Mayo Clinic, explains how Mayo Clinic is managing staff, supplies and space during the COVID-19 surge.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
December 3, 2020
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Be Safe Not Sorry: Teaching Patients Proper Handwashing Technique

Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Many of us learned how to wash our hands at a very early age and have relearned the importance and proper technique periodically along the way. Research suggests that many people may not be doing it correctly. Dr. Greg Poland a Professor of Medicine in Infectious Disease at the Mayo Clinic joins us for National Hand Washing Awareness Week to discuss some tips and tricks to share with your patients to ensure they’re reaching the full potential of this life-saving technique. He’ll also answer questions like does it matter if the water is hot? Is handwashing with soap more effective than anti-bacterial gel or lotions? And, when should we be washing our hands? Additional resources mentioned (not an endorsement or affiliation): Glo Germ: Visual Tool for Handwashing https://www.glogerm.com/  Jimmy Kimmel and Guillermo Learn How to Wash Their Hands https://youtu.be/sJfsyhQ0oBs Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
December 1, 2020
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COVID-19 Miniseries Episode 54: The Enigma of COVID-19 Long Haulers

This episode was recorded on November 17th, 2020.Guest: Raymund R. Razonable, M.D. (@RazonableMD)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)What causes some patients to develop Long Haul COVID-19? Dr. Raymund Razonable discusses what the current data is showing and what we’re hoping to learn from future research.Deeper dive:As Their Numbers Grow, COVID-19 “Long Haulers” Stump Expertshttps://jamanetwork.com/journals/jama/fullarticle/2771111AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 25, 2020
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Celiac Disease

Guest: Joseph A. Murray, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) The diagnosis and management of Celiac Disease is discussed with Dr. Joseph Murray, a gastroenterologist from the Mayo Clinic. Specific topics discussed include:Typical presentations of Celiac Disease in children and adultsDifficulties encountered in establishing a diagnosisSmall bowel pathology seen in Celiac DiseaseMechanism for malabsorption in Celiac DiseaseRisk factors for Celiac DiseaseCeliac Disease and pregnancyHow to confirm a diagnosis of Celiac DiseaseLaboratory testsNecessity of a small bowel biopsyManagement of Celiac DiseaseChallenges in maintaining a gluten-free dietPotential long-term complications of Celiac DiseaseConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 24, 2020
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Hepatits C

Guest: John J. Poterucha, M.D.Host: Darryl S. Chutka, M.D. (@ChutkaMD) The topic of Hepatitis C, including risk factors, evaluation and management was discussed with Dr. John Poterucha, a gastroenterologist from the Division of Gastroenterology and Hepatology. Specific topics discussed include:Serologic testing for hepatitis CSymptoms of hepatitis CRisk factors for hepatitis CTransmission of hepatitis C during pregnancyRisk of hepatitis C transmission following a needle-stick exposureIdentifying which patients should be tested for hepatitis CNatural history of hepatitis CPotential complications of hepatitis CAvailable pharmacologic treatmentPotential for reinfection with hepatitis CHepatitis C and liver transplantationPotential for an effective hepatitis C vaccineConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 17, 2020
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Mayo Clinic Q&A: Fighting COVID-19 with Mayo Clinic Laboratories

This episode is shared from Mayo Clinic Q&A and was recorded in November, 2020. Guest: William G. Morice, II, M.D., Ph.D. (@moricemdph)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd) When the COVID-19 pandemic began, one of the areas of science and research most affected was laboratory medicine. From developing tests that detect the virus, to testing for antibodies in patients who have recovered, Mayo Clinic Laboratories has been at the forefront of COVID-19 testing and research. On the Mayo Clinic Q&A podcast, Dr. William Morice II, president of Mayo Clinic Laboratories and chair of the department of Laboratory Medicine and Pathology at Mayo Clinic, explains how a reference lab works and how Mayo Clinic Laboratories quickly ramped up its testing capability to meet pandemic testing needs. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
November 12, 2020
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Influenza Vaccine: Nurses Call the Shots

Guest: Robert M. Jacobson, M.D. (@RobertJMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) It is extremely important that our patients receive the influenza vaccine this year. In previous years, less than half of the population has received it. Dr. Robert Jacobson, a pediatrician and vaccine specialist at the Mayo Clinic, joins us to discuss the reasons it’s so important for our patients to receive the influenza vaccine this season.  He’ll share tips for discussing common concerns from vaccine-hesitant patients and how you can increase your patient vaccination rates. Specific topics discussed: Importance of the influenza vaccine for our patients in 2020/2021 How and when the influenza vaccine is developed for the next influenza season Why we need an influenza vaccine on an annual basis The best time of the year to receive the influenza vaccine Whether we lose some immunity to influenza if we receive the vaccine too early in the year Which vaccine should be given to those 65 years and older Common myths surrounding the influenza vaccine Predictions for the severity of influenza for 2020/2021 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
November 10, 2020
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Caring for Patients with Dementia

Guest: Ericka E. Tung, M.D.Host: Darryl S. Chutka, M.D. (@ChutkaMD) The topic of Alzheimer’s Disease and other dementias was discussed along with the importance of providing care of the patient’s care-givers by Dr. Ericka Tung, a geriatrician in the Division of Community Internal Medicine at the Mayo Clinic. Specific topics discussed include:Common symptoms seen in early dementia.Mild cognitive impairment and its progression to dementia.Importance of stability of lifestyle in the life of patients with dementia.Discussing the diagnosis of dementia with the patient and family.Using a mental status exam in the evaluation of patients with suspected dementia.Establishing a diagnosis in patients with early dementia.The role of formal psychological testing in patients with suspected dementia.The needs of care-givers of dementia patients.Importance of respite care for the care-givers of dementia patients.Evaluating driving skills in patients with early dementia.Advanced care planning for dementia patients.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
November 3, 2020
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COVID-19 Miniseries Episode 53: Mayo Clinic Q&A – CDC Updates Close Contact Guidelines

This episode is shared from Mayo Clinic Q&A and was recorded in October, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The Centers for Disease Control and Prevention (CDC) has updated its guidelines for defining close contact with a person who is positive for COVID-19. Previously, close contact was defined as occurring when someone was within 6 feet of an infectious person for 15 consecutive minutes. Now close contact includes people who were within 6 feet for a total of 15 minutes over a 24-hour period, as the CDC now advises that repeated, brief encounters also carry a risk of transmission. On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, discusses the updated information from the CDC and the latest information from the Food and Drug Administration on COVID-19 treatments and vaccines. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 28, 2020
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Chronic Obstructive Pulmonary Disease (COPD)

Guest: Lewis J. Wesselius, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD)  The topic of COPD including risk factors, evaluation and management is discussed with Dr. Lewis Wesselius, a pulmonologist in the Division of Thoracic Disease at the Mayo Clinic. Specific topics discussed include the following:Review of the various types of COPD.Similarities and differences between emphysema and chronic bronchitis.Financial complications of COPD.Risk factors for COPD.Appropriate tests to order when evaluating patients suspected of having COPD.Determining the severity of COPD.Management of patients with COPD including the role of bronchodilators, inhaled corticosteroids, antibiotics and oxygen.COPD and the risk of lung cancer.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
October 27, 2020
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Allergies and Anaphylaxis

The topic of anaphylaxis is reviewed including its causes, management and potential complications by James T C Li, M.D., Ph.D., an allergist from the Division of Allergic Disease from the Mayo Clinic. Specific topics discussed include the following:Truths vs. myths regarding anaphylaxis Common manifestations and presentations of anaphylaxis Triggers which more commonly produce an anaphylactic reaction Anaphylaxis in patients without a history of allergies When to use antihistamines in treating an allergic reaction When and how to prescribe epinephrine in treating patients with a history of allergic reactions Issues related to epinephrine auto-injectors Natural history of allergies over time Developments in peanut allergies Management of an anaphylactic reaction Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 20, 2020
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Differentiating Common Causes of Shoulder Pain

Guest: Christopher Camp, M.D. (@ChrisCampMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The shoulder is unique in both structure and function. Injuries can occur acutely or overtime from wear and tear. If a patient presents with shoulder pain, when do you order imaging? What is role of steroid injections? When should a patient apply ice or apply heat? Dr. Christopher Camp, an orthopedist from Orthopedics and Sports Medicine at the Mayo Clinic joins us to discuss common injuries broken down by age demographic, treatment options, and when you may need to refer to a surgeon.   The following topics are discussed: Anatomy of the shoulder joint and what makes it a unique joint. Injuries which commonly occur in both younger and older patients. Review of common pathologic conditions of the shoulder: Rotator cuff injuries Impingement syndrome Bursitis of the shoulder  “Frozen shoulder”  When a steroid injection of the shoulder is of benefit.  When an X-ray or MRI of the shoulder is of benefit in the evaluation of shoulder pain.  Benefits of physical therapy in patients with shoulder pain/injuries.  The use of heat or cold in treating shoulder pain.  When patients should be referred to an orthopedist for evaluation of shoulder pain.  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 13, 2020
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COVID-19 Miniseries Episode 52: Mayo Clinic Q&A – How Do Antiviral Drugs Work?

This episode is shared from Mayo Clinic Q&A and was recorded in October, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Antiviral drugs are medicines that fight against viruses in the human body by impeding the infection process. Antivirals are commonly used to treat HIV/AIDS, influenza, herpes, and hepatitis B and C. The antiviral, Remdesivir, which was originally developed to fight Ebola, is now being used to treat  COVID-19. On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, explains how antivirals work to shorten the course of the disease.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 7, 2020
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The Evolution of Pharmacogenomics

Guest:  Richard Weinshilboum, M.D.Host: Darryl S. Chutka, M.D.In a similar way to how anesthesia changed the practice of surgery, pharmacogenomics will produce a similar change in how we prescribe medications. Listen in to world-renowned expert Dr. Richard Weinshilboum discuss the evolution of the field and how advances are accelerating its application at the bedside. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
October 6, 2020
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Mayo Clinic Q&A: Transplant Surgeries and COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in September, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Patrick G. Dean, M.D. Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) Transplants are identified as nonelective surgeries, and transplant patients have faced urgent medical needs during the COVID-19 pandemic. "Our practice, like many others across the country, did slow down in March and April of this year," says Dr. Patrick Dean, a Mayo Clinic transplant surgeon. "Patients and providers were concerned ― appropriately so ― about what would happen with this pandemic and whether it would be safe to have a transplant or for that matter any health care that wasn't absolutely emergent." In this Mayo Clinic Q&A podcast, Dr. Dean talks about taking care of transplant patients; overcoming surgery challenges during the pandemic; the increased risks transplant patients have of developing SARS-CoV-2, the virus that causes COVID-19, because of compromised immune systems; and the important need for COVID-19 testing. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 30, 2020
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Updates in the Evaluation and Treatment of Multiple Sclerosis

Guest: Eoin Flanagan, M.B., B.Ch., Department of Neurology, Mayo ClinicThis episode will review the following topics regarding Multiple Sclerosis (MS):- Common presenting symptoms- Risk factors, including the association of MS and vitamin D- Typical pathologic changes found in patients- The difference between the relapsing and progressive forms of MS- Laboratory and imaging studies which are helpful in confirming a diagnosis - Established and new treatment options available Available useful resources for patients with MS- Mayo Clinic website on Multiple Sclerosis- National MS Society
September 29, 2020
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Mayo Clinic Q&A: #AskTheMayoMom about COVID-19 and School Children

This episode is shared from Mayo Clinic Q&A and was recorded in September, 2020. Guest:  Angela C. Mattke, M.D. (@DrAngelaMattke) Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) The COVID-19 pandemic continues to create challenges, including returning to school with hybrid learning modules for children. There are also anxieties and uncertainties to navigate, while trying to follow COVID-19 guidelines. In this "Mayo Clinic Q&A" podcast, Dr. Angela Mattke, a Mayo Clinic pediatrician and host of #AskTheMayoMom, talks about the concerns her patients have, and what important things parents and caregivers should take into consideration when helping children stay healthy. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 22, 2020
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COVID-19 Miniseries Episode 51: Mayo Clinic Q&A – Bringing COVID-19 Vaccines to the Public

This episode is shared from Mayo Clinic Q&A and was recorded on September 14, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Danielle Stiepan Once a vaccine to prevent COVID-19 is approved, there will be logistics to consider. For example, who will receive the vaccine first, and how can the supply chain safely deliver the vaccine to 330 million Americans and potentially more than 7 billion people worldwide? In addition, multiple vaccines may be brought to market within weeks to months of each other, confusing consumers. On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, explains the challenges of rolling out a COVID-19 vaccine. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 17, 2020
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Updates for Diabetes Treatment and Monitoring

Guest:  Bithika M. Thompson, M.D. Host: Darryl S. Chutka, M.D. Dr. Bithika Thompson discusses the recognition and treatment of pre-diabetes, individualizing glycemic control goals for patients based on a series of variables, and recent advances in technology for monitoring that help to decrease the burden of care. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 15, 2020
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An Essential Update in Preventative Cardiology in the Time of COVID-19

To register for notification when the 94th Annual Clinical Reviews Course opens visit: https://mayocl.in/2GvecAd Guest:  Stephen L. Kopecky, M.D. With underlying cardiovascular disease as the most lethal comorbidity to have in association with COVID-19, what have we learned about how SARS-CoV-2 affects the heart and what correlation is seen between patients with cardiometabolic disorders and preventative health measures? Dr. Stephen Kopecky shares lessons learned for all cardiologists, all caregivers, and all patients. “The cardiovascular risk profile that we use from the American College of Cardiology, from the American Heart Association, looks at hypertension, looks at smoking, looks at diabetes, and looks at lipids. That risk profile predicts cardiovascular complications. So it not only predicts disease but it predicts the complications of COVID infection.” AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 8, 2020
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COVID-19 Miniseries Episode 50: Mayo Clinic Q&A – COVID-19 – Essential Updates with Dr. Poland

This episode is shared from Mayo Clinic Q&A and was recorded in July, 2020. Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, covers the latest news on the COVID-19 pandemic. Dr. Poland gives an update on progress towards a vaccine for COVID-19, discusses therapies for treating the virus and shares research on how effective face masks and physical distancing are in fighting the spread of the disease. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
September 4, 2020
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Mayo Clinic Q&A – A Healthy Mindset to Start the School Year

This episode is shared from Mayo Clinic Q&A and was recorded in August, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Craig N. Sawchuk, Ph.D., L.P. (@CraigSawchukPhD) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The start of a new school year is always a time that’s filled with excitement and anxiety. This year, COVID-19 is making back to school even more challenging for kids, teachers and parents. Whether in person, online or a hybrid approach, this school year will be different for students and staff. How can you and your child have a healthy mindset for this school year? On the Mayo Clinic Q&A podcast, Dr. Craig Sawchuk, chair of the Division of Integrated Behavioral Health at Mayo Clinic, shares helpful tips and strategies to be resilient and handle the challenges of a school year during the COVID-19 pandemic. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
September 2, 2020
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COVID-19 Miniseries Episode 49: Mayo Clinic Q & A – COVID-19 Back-To-School Recommendations

This episode is shared from Mayo Clinic Q&A and was recorded in August, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD) Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)Whether in person, online or a hybrid model of education, families and school districts are planning for how to safely teach students during the COVID-19 pandemic. No matter which plan is chosen by communities, this school year will be challenging.On the Mayo Clinic Q&A podcast, Dr. Nipunie Rajapakse, a pediatric infectious disease specialist at Mayo Clinic, discusses how students, teachers and staff can use public health measures already in place to minimize the risk of exposure to the virus and reduce community spread of COVID-19.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
August 31, 2020
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Regenerative Medicine Takes on Hair Loss

Guest: Alison J. Bruce, M.B., Ch.B. & Shane A. Shapiro, M.D. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Androgenic alopecia can have a significant impact on women across a spectrum of age. The psychological and social impact of hair thinning and hair loss can significantly decrease quality of life. Dr. Alison Bruce breaks down different types of hair loss, who’s a candidate, and new therapies on the horizon. Dr. Shane Shapiro will discuss the application of regenerative medicine to this condition and how platelet rich plasma has demonstrated efficacy at regrowing hair. Deeper Dive: A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women doi: 10.1097/DSS.0000000000002168 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
August 25, 2020
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COVID-19 Miniseries Episode 48: Neutralizing Antibody Assay, Explained

This episode is shared from Answers from the Lab and was originally published June 30, 2020. Guest: John R. Mills, Ph.D. Host: Bobbi S. Pritt, M.D. (@ParasiteGal) John Mills, Ph.D., is the co-director of the Neuroimmunology Laboratory at Mayo Clinic and the scientist who oversaw the development and validation of the new neutralizing antibody assay. Today he joins us to explain what the neutralizing antibody assay is, why it is different than other COVID-19 tests, and the science and innovation behind these efforts. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd 
August 21, 2020
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Answers from the Lab: Future of COVID-19 Laboratory Testing

This episode is shared from Answers from the Lab and was originally published June 25, 2020. Guest: William G. Morice, II M.D., Ph.D. (@moricemdphd) Host: Bobbi S. Pritt, M.D. (@ParasiteGal) William Morice, II, M.D., Ph.D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. In this episode, Dr. Morice discusses the future of testing for COVID-19, predicting who would be at the highest risk for severe disease, and challenges with existing diagnostics. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd 
August 19, 2020
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Sorting Out Knee Pain and Treatment Opportunities

Guest: Daniel B. Saris, M.D., Ph.D. (@sarisnl) Host: Darryl S. Chutka, M.D. (@ChutkaMD) With over 12 million outpatient visits annually in association with knee pain, it’s a common presentation in primary care. Dr. Daniel Saris discusses what questions we should be asking our patients, when to order imaging studies, and the common causes of pain broken down by age demographic. He’ll also discuss stem cell therapy, who is a good candidate, and who isn’t. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
August 18, 2020
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COVID-19 Miniseries Episode 47: Serology Testing for COVID-19

This episode is shared from Answers from the Lab and was originally published June 16, 2020. Guest: Elitza Theel, Ph.D. (@ElliTheelPhD) Host: Bobbi S. Pritt, M.D. (@ParasiteGal) Elitza Theel, Ph.D., Laboratory Director of the Infectious Diseases Serology Laboratory at Mayo Clinic, led the efforts to evaluate and implement the serologic antibody test for COVID-19. She gives an overview of Mayo Clinic’s COVID-19 antibody test, as well as the role of antibody testing during the pandemic, and how sensitivity, specificity, and prevalence play a large role in the positive predictive value of a test. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd 
August 17, 2020
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COVID-19 Miniseries Episode 46: Physician Leaders and the Science of Health Care Delivery

This episode was recorded August 6, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Lisa A. McGee, M.D. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) What are population centered care and health? How do we best use rationed resources within our health care system to most effectively meet these needs? Dr. Lisa McGee discusses the Science of Health Care Delivery,  the impact mass media messages have had on the current COVID-19 pandemic, and how we can use the information we have about population centered health to address key influential components of SARS-CoV-2’s continual spread. Suggested Readings: The effect of public health measures on the 1918 influenza pandemic in U.S. cities https://doi.org/10.1073/pnas.0611071104 Public health interventions and epidemic intensity during the 1918 influenza pandemic  https://doi.org/10.1073/pnas.0610941104 AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
August 11, 2020
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COVID-19 Miniseries Episode 45: There Is No Win-Win

This episode was recorded on June 26, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Pritish K. Tosh, M.D. (@DrPritishTosh) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Novel viruses causing outbreaks tend to do one of three things: disappear completely, become endemic in certain areas, or roll through populations with ongoing transmission until herd immunity is achieved or an effective vaccine is developed. Dr. Pritish Tosh states, “If natural infection doesn’t cause long-lasting protective immunity or the vaccines don’t do the same, this thing could be with us for a long time.” Take a walk through the past 100 years of pandemics as Dr. Tosh draws comparisons and lessons learned. The Economist - The Grim Calculus https://www.economist.com/leaders/2020/04/02/covid-19-presents-stark-choices-between-life-death-and-the-economy AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
August 4, 2020
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COVID-19 Miniseries Episode 44: Supply Chain Vulnerability – Why Don’t We Have Enough PPE?

This episode was recorded on June 26, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Pritish K. Tosh, M.D. (@DrPritishTosh) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) “Everybody has a plan until they get punched in the mouth.” - Mike Tyson Thin margins and economies of scale help lower costs but can create significant vulnerabilities. Often calculations of lives lost in the event of a shortage or costs to stockpile may not be factored in when sourcing supplies. Healthcare supply chain practices over decades have lead to significant weak points in our supply chains for some vital materials and we often have no view of this until it’s too late. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
July 28, 2020
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COVID-19 Miniseries Episode 43: Healthcare Disparities and Systemic Racism

This episode was recorded June 25, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Kenneth G. Poole, Jr. M.D., M.B.A. (@KPooleMD) Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Black, Latino, and Native American populations have been disproportionately affected by COVID-19. Underlying health inequities have been a major contributor. Dr. Kenneth Poole discusses social determinants of health and how these combined with systemic racism, predating COVID-19, laid the groundwork for the suffering we’re seeing unfold. What can we do to address it effectively? COVID-19 and African Americans - Clyde Yancy https://jamanetwork.com/journals/jama/fullarticle/2764789 AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
July 21, 2020
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COVID-19 Miniseries Episode 42: The Impact of Care Disruption for Patients with Non-Emergent Needs

This episode was recorded May 19, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  Sidna M. Tulledge-Scheitel, M.D., M.P.H.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) The COVID-19 pandemic has caused waves of care disruption for people around the world. What patient populations have faced unique risks? What signs of impact from the temporary restriction of medical outpatients services are we seeing? Dr. Tulledge-Scheitel shares what’s being seen at Mayo Clinic, what she anticipates we’ll be seeing in the coming months, and what she’d do should this need arise again in the future.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
July 14, 2020
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COVID-19 Miniseries Episode 41: Breaking Down the Impact of Smoking in COVID-19 Part 2

This episode was recorded June 17, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:   J. Taylor Hays, M.D. (@jtaylorhays), Robert Vassallo, M.D.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Is the act of smoking a risk factor for transmission? Does nicotine protect against severe COVID-19? Dr. Hays and Dr. Vassallo discuss what is currently known about the risks of smoking in regard to COVID-19 and treatment of patients who smoke, during the pandemic.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
July 9, 2020
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COVID-19 Miniseries Episode 40: Breaking Down the Impact of Smoking in COVID-19 Part 1

This episode was recorded June 17, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  J. Taylor Hays, M.D. (@jtaylorhays), Robert Vassallo, M.D.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Is smoking a risk factor for severe disease in COVID-19? How accurate is the documentation of smoking in COVID-19 cohorts currently published? What role should a smoking history play in the prognosis and management of COVID-19? Drs. Hays and Vassallo discuss the prevalence of smoking worldwide, the impact of documentation, and the role smoking may play in COVID-19.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
July 7, 2020
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COVID-19 Miniseries Episode 39: The Pro-Inflammatory Consequences of SARS-CoV-2 Infection

This episode was recorded May 20, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Joseph T. Poterucha, D.O. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) As documented infection rates pass the half-million mark, we check in with Dr. Joseph Poterucha, a Critical Care specialist at Mayo Clinic, to get an overview of what they’re seeing in the ICU with patients infected with SARS-CoV-2. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 30, 2020
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COVID-19 Miniseries Episode 38: The Enduring Power of Compassion

This episode was recorded on May 13, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  David J. Rosenman, M.D. (@davidrosenman)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) “At a time when most of the world in one way or another is suffering, it seems relevant to talk about ways to relieve some of that suffering and to help.” Studies have shown that patients value empathy over sympathy, and compassion over empathy. While measures to protect ourselves and understand the spread of COVID-19 and the clinical presentation of the disease are underway, the inconsistency of information across sources brings greater uncertainty for our patients and at times ourselves. Dr. Rosenman discusses what compassion is and the importance of compassion as a tool to help us and our patients, feel better mentally and physically. He recommends practicing self-compassion and will step through the practices of self-kindness, common humanity, and mindfulness. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 26, 2020
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COVID-19 Miniseries Episode 37: Movement is Medicine

This episode was recorded on May 28, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  Edward R. Laskowski, M.D. (@DrEdSportsMed)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) The world was already facing an epidemic of inactivity prior to the emergence and spread of SARS-CoV-2. Some have been able to focus more on self-care and fitness while under stay-at-home measures but with the necessity of social distancing and the widespread closure of fitness centers others have encountered significant challenges. What is the real cost of inactivity? Whether it’s the “Quarantine 15” or the psychological effects of being isolated in a world constantly changing, Dr. Laskowski shares one of the most effective treatments you can recommend to your patients.Deeper Dive:Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aginghttps://doi.org/10.4065/mcp.2011.0252Strength training: How-to video collectionhttps://www.mayoclinic.org/healthy-lifestyle/fitness/in-depth/strength-training/art-20046031Physical Activity Guidelines for Americanshttps://www.hhs.gov/fitness/be-active/physical-activity-guidelines-for-americans/index.htmlAskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 19, 2020
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Mayo Clinic Q & A – Medical Education During the COVID-19 Pandemic

This episode is shared from Mayo Clinic Q&A and was recorded in June, 2020.Guest:  Alexandra P. Wolanskyj-Spinner, M.D. (@apw01)Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)Across the world, one of the biggest changes forced by the COVID-19 pandemic is in the field of education. Programs from kindergarten through postsecondary have rapidly moved to a distance learning model. Online and remote instruction has its own unique challenges, and has required students and educators to be creative to stay connected.On the Mayo Clinic Q&A podcast, Dr. Alexandra Wolanskyj-Spinner, senior associate dean for student affairs at the Mayo Clinic Alix School of Medicine in Minnesota, discusses medical education during the COVID-19 pandemic.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 10, 2020
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COVID-19 Miniseries Episode 36: A Comprehensive Update on COVID-19

This episode was recorded on June 5, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest: Raymund R. Razonable, M.D. (@RazonableMD)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Up to about 50% of people infected with SARS-CoV-2 are asymptomatic spreaders. About 80% of those who are symptomatic, developing COVID-19, have mild disease displaying dry cough, fever, and fatigue. The resulting 20% of symptomatic patients accounts for those who develop progressive respiratory distress and sometimes multi-organ failure, among other complications. We’re learning more about anosmia, cardiac injury, and “COVID-toes.” What’s known about COVID-19 and SARS-CoV-2 continues to evolve. Dr. Raymund Razonable walks through a recently published update on the management of COVID-19. Time Stamps:1:18 - New signs and symptoms of COVID-19. 3:30 - Testing characteristics (sensitivity, specificity, and indications)  of the molecular and serologic testing for SARS-CoV-26:22 - Risk factors and the prediction of disease progression for patients hospitalized with COVID-199:28 - Hyper-inflammatory syndrome and progression to multi-system organ failure syndrome10:45 - Multisystem inflammatory syndrome in children (MIS-C) 11:22 - Cardiac complications - 3 factors12:50 - Diagnosis and treatment of co-infection in hospitalized patients (COVID-19 and flu, COVID-19 and pneumonia)16:31 - Evidence-based treatment based on the 3 phases of COVID-19 viremic phase, pneumonic phase, hyperinflammation phase18:06 - Remdesivir update21:00 - Hydroxychloroquine update23:25 - Favipiravir and lopinavir-ritonavir update23:53 - Treatment of the hyperinflammatory phase (sarilumab, tocilizumab, lenzilumab, anakinra,)27:13 - Convalescent plasma28:04 - Discharge and social determinants of health33:40 - Telehealth and remote monitoring35:40 - Health disparities and telehealth37:47 - What’s the next development Infectious Disease specialists are looking for in relation to the COVID-19 pandemic?See the article here:A Collaborative Multidisciplinary Approach to the Management of Coronavirus Disease-19 in the Hospital Setting https://doi.org/10.1016/j.mayocp.2020.05.010AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 8, 2020
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COVID-19 Miniseries Episode 35: Alternative Ventilation Strategies

This episode was recorded on May 12, 2020.Guest:  James E. Baker, R.R.T., L.R.T. &  Steven R. Holets, R.R.T., L.R.T.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) What are some alternative ventilation strategies we can use to treat patients with COVID-19? James Baker, R.R.T., L.R.T. and Steve Holets, R.R.T., L.R.T. discuss individualizing care, limitations based on device design, and supply chain concerns.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
June 3, 2020
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COVID-19 Miniseries Episode 34: Multi-System Inflammatory Syndrome (MIS-C) in Pediatric Patients

This episode was recorded on May 27, 2020.Guest:  Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Patients under 21 who present with fever, lab evidence of inflammation, multisystem involvement, and recent or current SARS-CoV-2 infection fall under the case definition for multisystem inflammatory syndrome. They commonly present with persistent fever and gastrointestinal symptoms and concerningly, shock. Why are we seeing disproportionate rates in children of racial and ethnic minorities? Dr. Nipunie Rajapaske concisely covers what’s known about this syndrome and the data supporting its emergence as a post-infection complication.CDC Health Advisory on Multisystem Inflammatory Syndrome in Children (MIS-C)https://emergency.cdc.gov/han/2020/han00432.aspAn outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort studyhttps://doi.org/10.1016/S0140-6736(20)31103-XAskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 29, 2020
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COVID-19 Miniseries Episode 33: Mayo Clinic Q&A – COVID-19 Transmission Risks and Precautions

This episode is shared from Mayo Clinic Q&A and was recorded on May 26, 2020.Guest:  Gregory A. Poland, M.D. (@drgregpoland)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)According to the Centers for Disease Control and Prevention, the most common mode of transmission for COVID-19 is through close contact from person to person. While it is possible that someone can get COVID-19 by touching a surface or object that has the virus on it and then touching their own mouth, nose or possibly their eyes, this isn’t thought to be the main way the virus spreads.On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, discusses virus transmission and steps to take to keep yourself safe.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 28, 2020
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COVID-19 Miniseries Episode 32: The Fierce Urgency of Now – Pursuing a Safe and Efficacious Vaccine

This episode was recorded May 22, 2020To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Gregory A. Poland, M.D. (@drgregpoland)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) SARS-CoV-2, as an RNA virus, has marked capacity for mutation and recombination events. How do we build an efficacious and safe vaccine against it? How could we safely speed up development? Is a vaccine neutralizing the spike protein enough? Dr. Greg Poland returns to give you an update from the front lines of research on vaccine development and ongoing clinical trials.Dr. Poland’s Editorial:Tortoises, hares, and vaccines: A cautionary note for SARS-CoV-2 vaccine developmenthttps://doi.org/10.1016/j.vaccine.2020.04.073 'I Have A Dream' Speech, In Its Entiretyhttps://www.npr.org/2010/01/18/122701268/i-have-a-dream-speech-in-its-entiretyOur 'Fierce Urgency of Now' -  Secretary Kathleen Sebeliushttps://obamawhitehouse.archives.gov/blog/2013/08/26/our-fierce-urgency-nowKing Legacy: 'Fierce Urgency of Now' Exists Today - Terri Moon Cronkhttps://www.defense.gov/Explore/Features/Story/Article/2059480/king-legacy-fierce-urgency-of-now-exists-today/AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 23, 2020
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COVID-19 Miniseries Episode 31: The Safety of Convalescent Plasma

This episode was recorded May 21, 2020Visit the program site here:  https://www.uscovidplasma.orgTo claim credit visit: https://ce.mayo.edu/covid19podcastGuest: Michael J. Joyner, M.D. (@DrMJoyner)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Convalescent plasma as a passive immunity strategy is not new. What nuances apply for it’s application to treating COVID-19? Is it safe? Is it efficacious? Dr. Michael Joyner, Principal Investigator for Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19, discusses what’s known about this treatment option, information that’s currently being gathered, and how you can get involved.AABB Coronavirus Resources: http://www.aabb.org/advocacy/regulatorygovernment/Pages/AABB-Coronavirus-Resources.aspxAskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 22, 2020
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COVID-19 Miniseries Episode 30: Mayo Clinic Q&A – Addressing Health Disparities Amplified by COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in May 2020.Guest: Irene G. Sia, M.D.; Mark L. Wieland, M.D.Host:  Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)Minorities are being affected disproportionately by the COVID-19 pandemic. Early data shows that African Americans and other U.S. ethnic minorities have contracted COVID-19 at a higher rate and experience greater sickness and a higher death rate than other Americans. On the Mayo Clinic Q&A podcast, Dr. Irene Sia, a Mayo Clinic infectious diseases expert, and Dr. Mark Wieland, a Mayo Clinic community internal medicine physician, discuss ethnic disparities and COVID-19, including research being done with the Rochester Healthy Community Partnership.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 20, 2020
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COVID-19 Miniseries Episode 29: Lab Medicine Rounds – Understanding COVID-Associated Coagulopathy

This episode is shared from Lab Medicine Rounds  and was recorded May 1, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest: Ariela L. Marshall, M.D. (@AMarshallMD)Host: Justin D. Kreuter, M.D. (@KreuterMD)What is COVID-Associated coagulopathy? Why is it so important to recognize early on? How does it differ from the typical disseminated intravascular coagulation (DIC) picture? Dr. Ariela Marshall details the lab patterns, implications for our patients, and what testing should be evaluated on patients being treated for COVID-19 and when.Time Stamps:00:00 Podcast Intro00:40 What is COVID-associated coagulopathy and why is it important to recognize this?02:45 How is this coagulopathy similar to or different from other coagulopathies that we commonly see in clinical practice?04:30 Is there recommended testing for COVID-associated coagulopathy?06:30 Can you explain what the soluble fibrin monomer test is?08:09 How is COVID-associated coagulopathy managed in terms of prophylactic anticoagulation, therapeutic anticoagulation, and prophylactic transfusion?14:23 What are a few lessons that you have learned during this pandemic so far?Resources: F.A. Klok, M.J.H.A. Kruip, N.J.M. van der Meer, et al., Incidence of thrombotic complications in critically ill ICU patients with COVID-19,Thrombosis Research (2020) https://doi.org/10.1016/j.thromres.2020.04.013  Thachil J, Tang N, Gando S, Falanga A, Cattaneo M...Iba T, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID‐19 https://doi.org/10.1111/jth.14810AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19ISTH COVID-19 ResourcesSubscribe to Lab Medicine Rounds here: https://news.mayocliniclabs.com/podcast/lab-medicine-rounds/Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 20, 2020
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COVID-19 Miniseries Episode 28: Reflections on Telehealth and Teaching

This episode was recorded April 30, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest: Christopher A. Aakre, M.D.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) How do you approach planning for telehealth visits? Dr. Chris Aakre discusses preparing by considering How am I going to assess this concern by video? What are you looking for? What are you hoping to see there? How are you best going to be able to instruct the patient? AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 19, 2020
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COVID-19 Miniseries Episode 27: Safely Individualizing the Approach to Treatment for COVID-19

This episode was recorded in May 6, 2020Claim credit here: https://ce.mayo.edu/covid19podcastGuest: Alice Gallo De Moraes, M.D.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Patients hospitalized with COVID-19 are presenting with and developing severe lung injury, thrombosis, heart injury, and renal insufficiency. What is the observed rate of ventilation? Dr. Alice Gallo De Moraes discusses an individualized approach to intubation for critical support of patients infected with SARS-CoV-2.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 15, 2020
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COVID-19 Miniseries Episode 26: Mayo Clinic Q&A – Atypical Kawasaki Disease, Recombination Events, and Antiviral Therapy Updates

This episode is shared from Mayo Clinic Q&A and was recorded in May 2020.To claim credit visit https://ce.mayo.edu/covid19podcastGuest:  Gregory Poland, M.D. (@drgregpoland)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, discusses how SARS-CoV-2 is mutating, atypical Kawasaki disease emerging in pediatric patients, updates in antiviral therapies and how scientists and researchers are rapidly gaining new knowledge about the virus and the disease that it causes.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 12, 2020
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COVID-19 Miniseries Episode 25: Mayo Clinic Q&A – Scaling Clinical Trials Through Teamwork

This episode is shared from Mayo Clinic Q&A and was recorded in May 2020.Click here to claim credit: https://ce.mayo.edu/covid19podcastGuest: Andrew D. Badley, M.D.Host: Halena M. Gazelka, M.D. (@hmgazelkamd)Thanks to its combination of practice, education, and research, Mayo Clinic has a strong foundation to respond quickly to a medical crisis such as COVID-19. As the SARS-CoV-2 virus spread worldwide, a research task force was formed at Mayo Clinic to review and approve research proposals related to the virus and the disease it causes. On the Mayo Clinic Q&A podcast, Dr. Andrew Badley, chair of Mayo Clinic’s COVID-19 research task force, gives an update on COVID-19 research activities at Mayo Clinic. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 11, 2020
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COVID-19 Miniseries Episode 24: AskMayoExpert COVID-19 Navigator

This episode was recorded on May 6, 2020.Guest:  Scott D. Eggers, M.D. (@sdze)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Wish you could find the easily digestible evidence-based information you're looking for with just a few clicks? AskMayoExpert COVID-19 Navigator is a free and open access point-of-care resource containing consensus-based clinical recommendations, protocols, and best practices. They’ve done the reviews, they’ve done the synthesis, so you can quickly read what you need to know and get back to your patients. Dr. Scott Eggers lays out how it was formed, how it’s being maintained, and what you can expect moving forward.Check out the tool here:AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19For more in-depth information on inpatient care for COVID-19 check out:https://ce.mayo.edu/criticalcareinsightsonlineConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 8, 2020
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Mayo Clinic Q&A: Disinfecting the Home After COVID-19 Infection

This episode is shared from Mayo Clinic Q&A and was recorded May 6, 2020.Guest:  Gregory Poland, M.D. (@drgregpoland)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)Spring has sprung, and, for many, spring cleaning is a ritual. During the COVID-19 pandemic, cleaning and disinfecting homes is more important than ever. The Centers for Disease Control and Prevention released new cleaning guidelines to help effectively fight COVID-19 as businesses, schools and public spaces reopen.On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, a Mayo Clinic infectious diseases expert, discusses effective cleaning tactics to combat coronavirus.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19CDC Guidelines: Reopening Guidance for Cleaning and Disinfecting Public Spaces, Workplaces, Businesses, Schools, and Homeshttps://www.cdc.gov/coronavirus/2019-ncov/community/reopen-guidance.htmlConnect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 8, 2020
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Mayo Clinic Q&A: The “Quarantine 15”

This episode is shared from Mayo Clinic Q&A and was recorded in May, 2020.Guest: Donald D. Hensrud, M.D., M.S. (@DonaldHensrudMD)Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar) It’s being called the "Quarantine 15" online — people poking fun at gaining weight while staying at home during the COVID-19 pandemic. Is it really a problem? Or does eating help cope with stress? And what about for kids? Public health researchers warn that COVID-19 related school closures will double out-of-school time this year, raising concerns about weight gain associated with summer recess for children. On the Mayo Clinic Q&A podcast, Dr. Donald Hensrud, director of the Mayo Clinic Healthy Living Program, discusses tips for healthy eating and exercising while staying at home. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 7, 2020
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COVID-19 Miniseries Episode 23: Mayo Clinic Q&A – Possible Neurological Effects of COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in May, 2020.Guest: Allen J. Aksamit, Jr. M.D.Host: DeeDee Stiepan (@deedeestiepan)Originally identified as a respiratory disease, some COVID-19 patients exhibit neurologic symptoms including stroke, loss of consciousness, headache, and even the loss of taste and smell. What's unknown is whether these are direct effects of the virus entering the nervous system, or consequences of the disease's effect on the body.On the Mayo Clinic Q&A podcast, Dr. Allen Aksamit Jr., a Mayo Clinic neurologist, discusses potential neurological effects of COVID-19.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 5, 2020
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COVID-19 Miniseries Episode 22: Mayo Clinic Q&A – Continuity of Care for Patients with Cancer

This episode is shared from Mayo Clinic Q&A and was recorded in May, 2020.Guest: Tanios S. Bekaii-Saab, M.D. (@GIcancerDoc)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)Because cancer treatments can weaken the immune system, cancer patients are at increased risk of complications from COVID-19. Despite these concerns, cancer patients often still need treatment, including going to the clinic or to the hospital, and many have questions about whether cancer should be treated differently during the COVID-19 pandemic.On the Mayo Clinic Q&A podcast, Dr. Tanios Bekaii-Saab, a Mayo Clinic oncologist, explains how cancer patients can safely continue their cancer treatment during the pandemic.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
May 4, 2020
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COVID-19 Miniseries Episode 21: Mayo Q & A – Maintaining Routine Vaccine Schedules During COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2020.Guest:  Tina Ardon, M.D. (@TinaArdon)Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)As the COVID-19 pandemic continues, the World Health Organization (WHO) says more than 117 million children in 37 countries may be missing out on the lifesaving measles vaccine. The WHO had issued some guidelines to help countries sustain immunization activities during the COVID-19 pandemic. On the Mayo Clinic Q&A podcast, Dr. Tina Ardon, a Mayo Clinic family medicine physician, discusses the importance of childhood vaccinations. Dr. Ardon also discusses masking guidelines for children during the COVID-19 pandemic.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 3, 2020
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COVID-19 Miniseries Episode 20: Leveraging Telehealth to Treat Patients with COVID-19 – Part 2

This episode was recorded on April 16, 2020.Guest: M. Nadir Bhuiyan, M.D. (@DrNadirMD); Ravindra Ganesh, M.B.B.S., M.D.; Ryan T. Hurt, M.D., Ph.D.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) While not all patients with COVID-19 will require hospitalization, many are seeking care and medical advice from their primary providers.  With public health measures limiting travel and clinical visits, the question facing many healthcare organizations is: how do they safely provide care and monitor patients with COVID-19?  In this two-part episode on telemedicine, Dr. Amit Ghosh speaks with Drs. Nadir Bhuiyan, Ravindra Ganesh, and Ryan Hurt about the Mayo Clinic COVID-19 Frontline Care Team and their efforts to establish a telemedicine practice for patients with COVID-19.  Listen as they share key steps to successfully providing remote care, address concerns of COVID-19 positive patients, and mobilize a multifunctional team of healthcare professionals.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 2, 2020
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COVID-19 Miniseries Episode 19: Leveraging Telehealth to Treat Patients with COVID-19 – Part 1

This episode was recorded on April 16, 2020.Guest: M. Nadir Bhuiyan, M.D. (@DrNadirMD); Ravindra Ganesh, M.B.B.S., M.D.; Ryan T. Hurt, M.D., Ph.D.Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) While not all patients with COVID-19 will require hospitalization, many are seeking care and medical advice from their primary providers.  With public health measures limiting travel and clinical visits, the question facing many healthcare organizations is: how do they safely provide care and monitor patients with COVID-19?  In this two-part episode on telemedicine, Dr. Amit Ghosh speaks with Drs. Nadir Bhuiyan, Ravindra Ganesh, and Ryan Hurt about the Mayo Clinic COVID-19 Frontline Care Team and their efforts to establish a telemedicine practice for patients with COVID-19.  Listen as they share key steps to successfully providing remote care, address concerns of COVID-19 positive patients, and mobilize a multifunctional team of healthcare professionals.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
May 1, 2020
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COVID-19 Miniseries Episode 18: Mayo Clinic Q&A – Pets, Ultraviolet Light, and Herd Immunity

This episode is shared from Mayo Clinic Q&A and was recorded on April 29, 2020To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  Gregory A. Poland, M.D.  (@drgregpoland)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)Each week, the Mayo Clinic Q&A podcast shares the latest information on the COVID-19 pandemic. On today's episode, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group, answers listeners' coronavirus questions. Topics include: pets and COVID-19, ultraviolet light and viruses, and herd immunity.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 30, 2020
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Mayo Clinic Q&A: The Critical Role of Respiratory Therapists

This episode was recorded in April, 2020.Guest: Daniel A. Diedrich, M.D.Host: Halena M. Gazelka, M.D. (@hmgazelkamd)COVID-19 was first identified late last year with a cluster of pneumonia cases caused by a new coronavirus. The COVID-19 disease process heavily affects the respiratory system, and patients often need oxygen support. The respiratory therapist plays a critical role in managing oxygen levels, placing breathing tubes, and managing the mechanical ventilator, when necessary.On the Mayo Clinic Q&A podcast, Dr. Daniel Diedrich, a Mayo Clinic anesthesiologist and critical care physician, discusses the role of the respiratory therapist from the time a patient presents with COVID-19 all the way through that patient's discharge.AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 29, 2020
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Mayo Clinic Talks COVID-19 Miniseries Episode 17: Rapid Data Collection for Development of Evidence-Based Guidelines

This episode was recorded on April 22, 2020.Guest:  Rahul Kashyap, M.B.B.S. (@Dr_SRKashyap)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Real time data collection is essential for developing evidence based guidelines when facing emerging pathogens. Dr. Rahul Kashyap discusses VIRUS, a multinational multicenter rapid data collection process and how you can participate. Discovery VIRUS COVID-19 Registry (@covid19registry) https://www.sccm.org/Research/Research/Discovery-Research-Network/VIRUS-COVID-19-Registry  NIH - Viral Infection and Respiratory Illness Universal Study[VIRUS]: COVID-19 Registry (COVID-19)  https://clinicaltrials.gov/ct2/show/NCT04323787  AskMayoExpert COVID-19 Resources:  https://askmayoexpert.mayoclinic.org/navigator/COVID-19  Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 29, 2020
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Mayo Clinic Q&A – Keeping Vulnerable Patient Populations Safe

This episode is shared from Mayo Clinic Q&A and was recorded in April, 2020.Guest:  Amanda Kubista OwenHost: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)People around the world have been under stay-at-home orders to prevent the spread of coronavirus. While this situation isn't ideal, it can be dangerous for some. For people in abusive situations, home may not be a safe environment.On the Mayo Clinic Q&A podcast, Amanda Kubista Owen, a Mayo Clinic social worker, discusses services available to help support people affected by domestic violence and why having a safety plan is important.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 24, 2020
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COVID-19 Miniseries Episode 16: Mayo Clinic Q&A – Outbreak Updates

This episode is shared from Mayo Clinic Q&A and was recorded April 22, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  Gregory A. Poland, M.D.  (@drgregpoland)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, covers the latest news on the COVID-19 pandemic. Dr. Poland discusses current outbreak numbers, why there may be a second wave of infections, and research on a vaccine.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 23, 2020
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COVID-19 Miniseries Episode 15: Recommendations for Care of Pregnant Patients

This episode was recorded on April 20, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest: Regan N. Theiler, M.D., Ph.D.  (@TheilerRegan)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Does pregnancy itself make a woman more susceptible to COVID-19? What advice should we be giving to pregnant women in the third trimester? How is remote monitoring being utilized? Dr. Regan Theiler discusses how they’re advising and caring for pregnant patients, what’s being reported as potential complications for pregnant patients who’ve been infected with SARS-CoV-2, and what isolation precautions should be applied during and after delivery.Deeper Dive:Mayo Clinic COVID-19 Resources for Providers  https://www.mayoclinic.org/medical-professionals/provider-relations/covid-19-resources-for-providersSociety for Maternal - Fetal Medicine: Clinical Guidance on COVID-19  https://www.smfm.org/covidclinicalSociety for Obstetric Anesthesia and Perinatology - COVID-19 Toolkit  https://soap.org/education/provider-education/expert-summaries/interim-considerations-for-obstetric-anesthesia-care-related-to-covid19/Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 22, 2020
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Mayo Clinic Q&A – Inside Mayo Clinic’s COVID-19 Research Task Force

This episode is shared from Mayo Clinic Q&A and was recorded April, 2020.Guest:  Andrew Badley, M.D. (@BadleyAndrew)Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)As the SARS-CoV-2 virus spread worldwide, a race began to develop testing protocols and ramp up research. Mayo Clinic's COVID-19 research task force is studying the virus, predicting hot spots, and working towards effective treatments and a vaccine.On the Mayo Clinic Q&A podcast, Dr. Andrew Badley, chair of Mayo Clinic’s COVID-19 research task force, gives an update on COVID-19 research activities at Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 22, 2020
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Mayo Clinic Q&A – How Public Health Measures Can Help Reopen the Country

This episode is shared from Mayo Clinic Q&A and was recorded on April 20, 2020.Guest:  Gregory Poland, M.D. (@drgregpoland)Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)As the COVID-19 pandemic continues, efforts are underway to find a new normal and begin to re-open the country and the economy. While people are eager for strict social distancing rules to end, public health measures, including testing and tracing for the virus, will be important tools needed to control the spread of the virus and prevent an uptick in new infections.On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, discusses the steps needed to reopen businesses, schools and other activities as the fight to control COVID-19 continues.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 21, 2020
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Mayo Clinic Q&A – Serology Testing for SARS-CoV-2 Antibodies

This episode is shared from Mayo Clinic Q&A and was recorded April 2020.Guest:  Elitza S. Theel, Ph.D.Host: Halena M. Gazelka, M.D. (@hmgazelkamd)A new serology test from Mayo Clinic Laboratories is being used to identify the presence of immune response to SARS-CoV-2, the virus that causes COVID-19. The serology test is intended only to detect antibodies to the virus. It does not diagnose recent or active infection. Mayo Clinic Laboratories also offers a molecular test to diagnose very recent or active infection. Both tests are important tools in the pandemic response. On the Mayo Clinic Q&A podcast, Dr. Elitza Theel, director of Mayo Clinic’s Infectious Diseases Serology Laboratory, explains why serology testing is initially focused on identifying people in areas where potential immunity is key, including front-line health care workers.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 20, 2020
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COVID-19 Miniseries Episode 14: An Overview of Pulmonary Critical Care for COVID-19 Patients

This episode was recorded on April 15, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  Alexander S. Niven, M.D. (@niven_alex)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) When a patient presents with dyspnea how can we reliably predict who will progress to respiratory failure? How can phenotypes of disease progression be utilized for optimizing selection of treatment modalities? Dr. Alex Niven discusses Fleischner Society recommendations for imaging as a COVID-19 screening tool, cytokine storm, ventilator-associated lung injury, post-ICU care syndrome, and humanity in critical care.Deeper Dive:Mayo Clinic COVID-19 Resources for Providers https://www.mayoclinic.org/medical-professionals/provider-relations/covid-19-resources-for-providersFleischner Society GuidelinesRubin G, Haramati L, Kanne J, et al. The role of chest imaging in patient management during the COVID-19 pandemic: A multinational consensus statement from the Fleischner Society. Radiology. 2020 April 07; p.201365. https://doi.org/10.1148/radiol.2020201365The Berlin DefinitionThe ARDS Definition Task Force. Acute Respiratory Distress Syndrome: The Berlin Definition. JAMA. 2012;307(23):2526–2533. doi:10.1001/jama.2012.5669Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 16, 2020
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Turning Down the Heat on Fibromyalgia

Guest: Sanjeev Nanda, M.D. (@SNandaMD)Host: Darryl S. Chutka, M.D. (@ChutkaMD)In 2016, diagnostic criterion was established, finally removing fibromyalgia as a “diagnosis of exclusion.” Still, given the number of manifestations, it’s a challenging disorder to evaluate and treat. Sanjeev Nanda, M.D., shares his expert insights on this complicated condition.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 14, 2020
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COVID-19 Miniseries Episode 13: Mayo Clinic Q&A – Pregnancy and COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in April 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD)Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)How is SARS-CoV-2 affecting pregnant women? Is breastfeeding safe? How can a pregnant woman protect herself from the disease? On the Mayo Clinic Q&A podcast, Dr. Nipunie Rajapakse, a pediatric infectious diseases specialist, will discuss COVID-19 and pregnancy.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 13, 2020
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COVID-19 Miniseries Episode 12: Harnessing Telehealth Without Sacrificing Safety

This episode was recorded on April 8, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest:  Christopher S. Russi, D.O. (@csrussi)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) How can telehealth be used to care for COVID-19 patients? How can we leverage telehealth to bring resources to rural facilities? Collaboration through telehealth can provide care where it’s convenient for patients, help offload cognitive burden from colleagues, and mitigate exposure and PPE challenges during this pandemic. Dr. Christopher Russi walks through how the process works and how it’s being leveraged at Mayo Clinic under typical circumstances and how it’s being utilized to triage and inform care for suspected and confirmed COVID-19 patients.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 9, 2020
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Mayo Clinic Q&A: Medical vs. Public Masking

This episode is shared from Mayo Clinic Q&A and was recorded on Monday, April 6th, 2020.Guest:  Gregory A. Poland, M.D.  (@drgregpoland)Host: Halena M. Gazelka, M.D. (@hmgazelkamd)To prevent the spread of COVID-19, the Centers for Disease Control and Prevention (CDC) now recommends that Americans wear cloth masks in public settings where other social distancing measures are difficult to maintain. The CDC considers cloth masks an additional, voluntary public health measure.On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, a Mayo Clinic COVID-19 expert, explains the difference between medical masking and public masking, and discusses the proper way to put a mask on and off to prevent the spread of disease.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. Deeper Dive:Use of Cloth Face Coverings to Help Slow the Spread of COVID-19
April 7, 2020
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Advanced Directives in Healthcare

Guest: Janet Vittone, M.D.Host: Darryl S. Chutka, M.D. (@ChutkaMD)Janet Vittone, M.D., outlines the difference between different advanced directive documents and the importance of discussing these with all of your patients. She shares tips on when and how to broach the topic with patients, especially those in early adulthood. Drs. Vittone and Chutka also discuss ensuring that the right people are aware of your wishes, should you become incapacitated.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.Deeper Dive:Living wills and advance directives for medical decisions, by Mayo Clinic: https://www.mayoclinic.org/healthy-lifestyle/consumer-health/in-depth/living-wills/art-20046303Patient education video: https://www.mayoclinic.org/healthy-lifestyle/consumer-health/multimedia/advance-directives-awarness/vid-20114292
April 7, 2020
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COVID-19 Miniseries Episode 11: Mayo Clinic Q&A – Antibody Testing and Collaboration in Science

This episode is shared from Mayo Clinic Q&A and was recorded on April 3, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest:  Gregory A. Poland, M.D.  (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) Dr. Greg Poland returns to share an update on the COVID-19 pandemic in this episode shared from Mayo Clinic Q&A to discuss the latest in antibody testing, coronavirus immunity, and whether or not it’s safe to wear contact lenses. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 6, 2020
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COVID-19 Miniseries Episode 10: How to Mitigate Drug-Induced Sudden Cardiac Death From Hydroxychloroquine

This episode was recorded on April 3, 2020Claim credit here: https://ce.mayo.edu/covid19podcastGuest:  Michael J. Ackerman, M.D., Ph.D. (@MJAckermanMDPhD)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)The administration of hydroxychloroquine and azithromycin, along with other very common medications could result in drug-induced sudden cardiac death caused by drug-induced QT prolongation, in some patients. In order to avoid the wrong medication, for the wrong patient, at the wrong time, Dr. Michael Ackerman shares how to assess your patient’s risk, how to find and measure their QTc value, and neutralize the threat.Deeper Dive:Link to Journal Pre-Proof:https://mayoclinicproceedings.org/pb/assets/raw/Health%20Advance/journals/jmcp/jmcp_covid19.pdfLink to COVID-19 QTc Calculator and other resources:https://www.covidqtc.com/#WRchTxt7-12veGiudicessi JR, Noseworthy PA, Friedman PA, Ackerman MJ. Urgent guidance for navigating and circumventing the QTc prolonging and torsadogenic potential of possible pharmacotherapies for COVID-19 [published online ahead of print March 25, 2020]. Mayo Clin Proc. https://doi.org/10.1016/j.mayocp.2020.03.024.FDA Emergency Use Authorization (EUA) of hydroxychloroquine sulfate: https://www.fda.gov/media/136538/downloadMayo Clinic Connected Care - Genetic Heart Rhythm Diseases https://connect.mayoclinic.org/page/genetic-heart-rhythm-disorders/tab/covid-19/#Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
April 3, 2020
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Mayo Clinic Q&A: The ‘Unprecedented Challenge’ of Fighting COVID-19

This episode is shared from Mayo Clinic Q&A.Guest: Elie Berbari, MD (@DODElie)Host: Tom Shives, MD and Tracy McCray (@TracyMcCray)The ongoing fight against the COVID-19 pandemic has heavily burdened front-line health care providers. "Our nation and our medical community is facing an unprecedented challenge," says Dr. Elie Berbari, chair of the Division of Infectious Diseases at Mayo Clinic. On the Mayo Clinic Q&A podcast, Dr. Berbari discusses how Mayo Clinic is minimizing exposure to staff, while providing safe and compassionate care to patients. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
April 2, 2020
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Mayo Clinic Q&A: How Does SARS-CoV-2 Make People Sick?

This episode is shared from Mayo Clinic Q&A and was recorded on March 31, 2020.Guest:  Gregory Poland, M.D.Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)A novel coronavirus is a new strain that has not been seen before in humans. SARS-Co-V2 is a novel virus, causing the disease COVID-19. Because COVID-19 is a new disease, much is still being learned about how it spreads and the severity of illness it causes. On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, infectious disease expert and head of Mayo Clinic’s Vaccine Research Group, explains the science behind how the virus makes people sick, and what the virus does to the body. Dr. Poland will also discuss the latest information on clinical trials and vaccine research to fight the disease outbreak.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 31, 2020
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A Rheumatologist’s Approach to Osteoarthritis

Guest: Alicia M. Hinze, M.D., M.H.S. (@alicia_hinze)Host: Darryl S. Chutka, M.D. (@ChutkaMD)Alicia M. Hinze, M.D., M.H.S., provides an overview of osteoarthritis and other rheumatologic conditions. Dr. Hinze shares her approach to distinguishing between osteoarthritis and inflammatory arthritis, along with risk factors for developing osteoarthritis over time, including genetics, professions, prior injuries, and age. She shares recommendations for conservative therapies and at what point surgical intervention should be considered.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 31, 2020
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COVID-19 Miniseries Episode 9: Recommendations on Ibuprofen

This episode was recorded on Monday, March 30, 2020.Claim credit here: https://ce.mayo.edu/covid19podcastGuest:  Matthew P. Van Cuyk, Pharm.D., R.Ph. Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Should we be using ibuprofen to treat patients with COVID-19? Does this fall into the modifiable risk category? Dr. Matthew Van Cuyk breaks down recent events and literature around ibuprofen use in patients with COVID-19. Deeper Dive:Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? The Lancet Respiratory Medicine. March 2020. https://doi.org/10.1016/S2213-2600(20)30116-8HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19ASHP Coronavirus Resource Center: https://www.ashp.org/Pharmacy-Practice/Resource-Centers/CoronavirusAssessment of Evidence for COVID-19-Related Treatments: Updated 3/27/2020For the most up to date COVID-19 information: CDC: https://www.cdc.gov/coronavirus/2019-ncov/index.htmlWHO: https://www.who.int/emergencies/diseases/novel-coronavirus-2019
March 31, 2020
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Mayo Clinic Q&A: Point-of-Care Manufacturing to Help Fight COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded on March 26, 2020.Guest:  Jonathan M. Morris, M.D. & Mark WehdeHost: Tom Shives, MD and Tracy McCray (@TracyMcCray)When it comes to fighting the COVID-19 pandemic, Mayo Clinic is relying not only on clinicians, but also engineers. Supply chain management and manufacturing capabilities are being readied to help in the fight against COVID-19.On the Mayo Clinic Q&A podcast, Dr. Jonathan Morris, co-director of Mayo Clinic's 3D Anatomic Modeling Lab, and Mark Wehde, chair of Mayo Clinic's Division of Engineering, discuss personal protective equipment and mobilizing the manufacturing sector to help in the fight. They’ll share how they’re utilizing 3D printing to jump start conventional scalable manufacturing processes to retro-engineer pieces of respiratory equipment and solve today’s problems in the fight against COVID-19.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 30, 2020
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COVID-19 Miniseries Episode 8: Azithromycin and Hydroxychloroquine

This episode was recorded on March 27, 2020.To claim credit visit: https://ce.mayo.edu/covid19podcastGuest: Christina G. Rivera, Pharm.D., R.Ph.; Ryan W. Stevens, Pharm.D. (@Stevens_AK)Host: Raymund R. Razonable, M.D. (@RazonableMD)Chloroquine emerged as an early COVID-19 treatment option in China and there has been increasing interest in the use of hydroxychloroquine and azithromycin. What data is available for the safety and efficacy of the drugs in the fight against SARS-CoV-2? Dr. Christina Rivera and Dr. Ryan Stevens provide a breakdown of recent research.Deeper Dive:Gautret P, Lagier JC, Parola P, et al. Hydroxychloroquine and Azithromycin as a treatment of COVID-19: preliminary results of an open-label non-randomized clinical trial. International Journal of Antimicrobial Agents. March 2020. https://doi.org/10.1016/j.ijantimicag.2020.105949Yao X, Ye F, Zhang M, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clinical Infectious Diseases. March 2020. https://doi.org/10.1093/cid/ciaa237Guidance on patients at risk of drug-induced sudden cardiac death from off-label COVID-19 treatments https://mayocl.in/2WQhxzIFor the most up to date COVID-19 information:CDC: https://www.cdc.gov/coronavirus/2019-ncov/index.htmlWHO: https://www.who.int/emergencies/diseases/novel-coronavirus-2019Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 27, 2020
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Mayo Clinic Q&A: Shifting from Me to We

This episode is shared from Mayo Clinic Q&A and was recorded on March 25, 2020.Guest: Greg Poland, MD (@drgregpoland)Host: Tom Shives, MD and Tracy McCray (@TracyMcCray)Greg Poland, MD, answers trending questions from listeners. Is it safe to order take-out or have groceries delivered? Can pets get coronavirus? What about our summer plans? What’s next for social distancing and is it working?Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 26, 2020
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Opioid Edition 10: Side Effects Management

Guest: Molly A. Feely, M.D. (@mollyfeelymd)Host: Tracy McCrayEpisode 10 of 10: Dr. Molly Feely, who is board-certified in palliative care, internal medicine, and family medicine now practicing full-time palliative care at Mayo Clinic in Rochester, talks about best practices for Management of Opioid Side Effects. Claim CME credit at ce.mayo.edu/opioidpc. This episode is required to be compliant with controlled substance prescribing guidelines in the state of Minnesota.
March 26, 2020
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COVID-19 Miniseries Episode 7: Anosmia – What’s Currently Known

This episode was recorded on March 25, 2020.Guest:  Erin K. O'Brien, M.D. (@ErinOBrienMD)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) Claim credit here: https://ce.mayo.edu/covid19podcastWhat’s currently known about anosmia as a symptom of COVID-19 infection? Should we be using it as a screening tool? What causes it to occur when someone is infected with SARS-CoV-2 and what’s the prevalence in symptomatic vs otherwise asymptomatic individuals? Dr. Erin O’Brien gives an up-to-date overview of current reports, treatment options, and what you need to know about anosmia.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 25, 2020
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COVID-19 Miniseries Episode 6: Mayo Clinic Q&A – The Latest Updates

Guest:  Greg Poland, MD (@drgregpoland)Host: Tom Shives, MD and Tracy McCray (@TracyMcCray)Claim credit for this episode at https://ce.mayo.edu/covid19podcastOn today's Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious disease expert and head of Mayo Clinic's Vaccine Research Group, shares the latest information on the COVID-19 pandemic. Dr. Poland discusses the importance of testing for SARS-CoV-2, work being done on antiviral medications; and how long social distancing might need to last, emerging reports of loss of smell in survivors, and the use of azithromycin and hydroxychloroquine.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 24, 2020
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Answering any Question You’ve Ever Had About Liver Function Testing

Guest: John J. Poterucha, M.D.Host: Darryl S. Chutka, M.D. (@ChutkaMD)You can think of liver functions tests as falling into two buckets – markers of inflammation and perturbation and markers of liver function. Dr. John Poterucha answers any question you’ve ever had about liver function testing, including how to interpret the results plus when and what additional testing may need to be ordered as follow up.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 24, 2020
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Mayo Clinic Q&A: Coping with Uncertainty

This episode is shared from Mayo Clinic Q&A.Guest: Beth Rush, PhDHost: Tom Shives, MD and Tracy McCray (@TracyMcCray)We are in the midst of uncertain times. Dr. Beth Rush, a Mayo Clinic neuropsychologist, shares tips for you and your patients about coping with uncertainty by creating a structured schedule. Listen in as she shares more tips for taking care of your mental health and finding comfort amid the uncertainty.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 23, 2020
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Mayo Clinic Q&A: Inflection Point

This episode is shared from Mayo Clinic Q&A and was recorded on March 19, 2020.Guest: Greg Poland, MDHost: Tom Shives, MD and Tracy McCrayHave we acted sufficiently to flatten the curve? When will we know? What does effective safe isolation look like?Infectious diseases expert Dr. Gregory Poland, a Mayo Clinic infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, answers new questions on COVID-19. How are we as a nation faring? What do you do when someone in your house is sick? Dr. Poland discusses preventive measures to stop the spread of the virus, what to do if you do get sick, and the potential for effective treatments and a vaccine.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
March 20, 2020
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Mayo Clinic Q&A: Isolation and Flattening the Curve

This episode is shared from Mayo Clinic Q&A and was recorded March 18, 2020.Guest: Clayton T. Cowl, M.D., M.S. (@ChestPresident) Host: Tom Shives, M.D. and Tracy McCrayIn epidemiology, the idea of slowing a virus' spread so that fewer people need to seek treatment at any given time is known as "flattening the curve." It's a phrase you've likely heard in the news, and it is an important goal for governments and health care leaders during the COVID-19 pandemic.On the Mayo Clinic Q&A podcast Dr. Clayton Cowl, chair of Mayo Clinic's Division of Preventive, Occupational and Aerospace Medicine, explains how isolation can stop a spike in the number of new coronavirus cases. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 
March 19, 2020
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Opioid Edition 9: Monitoring and Considerations for Tapering

Guest: Halena M. Gazelka, M.D. (@hmgazelkamd) Host: Tracy McCrayEpisode 1 of 10: Dr. Halena Gazelka, an anesthesiologist boarded in pain and palliative medicine at Mayo Clinic in Rochester, talks about best practices for Opioid Monitoring and Considerations for Tapering. This podcast is brought to you by the Opioid conference held each year as a part of Mayo Clinic’s Continuing Medical Education.Claim CME credit at ce.mayo.edu/opioidpc. This episode is required to be compliant with controlled substance prescribing guidelines in the state of Minnesota.
March 19, 2020
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Mayo Clinic Q&A: Taking Precautions in Long Term Care Facilities

This episode is shared from Mayo Clinic Q&A and was recorded March 17th, 2020. Guest: Brandon P. Verdoorn, M.D.Host: Tom Shives, MD and Tracy McCrayLong-term care facilities are taking steps to prepare and respond to the COVID-19 (coronavirus) outbreak. With guidance from the Centers for Disease Control and Prevention and the Centers for Medicare and Medicaid Services, long-term care facilities are restricting visitors in most cases.On the Mayo Clinic Q&A podcast, Dr. Brandon Verdoorn, a Mayo Clinic geriatrician and medical director of Charter House, a continuing care retirement community affiliated with Mayo Clinic in Rochester, explains how staff are taking steps to keep residents safe and prevent spread of the coronavirus.Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.