Out of Patients with Matthew Zachary

Out of Patients with Matthew Zachary

A podcast that calls out all sorts of stupid BS in healthcare through raw conversations about advocacy, heroism, and the audacity of health. It is the voice of patient advocacy.

Latest From Series

Michele Rhee: Thyroid Cancer, a Benign Heart Tumor, and Traversing All Seven Continents

On the show today, I welcome Michelle Rhee, young adult cancer survivor of Thyroid Cancer (you know, “the good one” I’M KIDDING) whose ordeal left her having over a dozen major surgeries, including open heart surgery for a related underlying rare disease. Back in the heyday when the young adult cancer movement was taking off, Michele was looking to take an active role in our startup culture. After being introduced, I helped land her an internship at the Children’s Cause for Cancer Advocacy, a landmark organization that everyone should know about, which helped launch my career in founding Stupid Cancer. She received BOTH her MBA and MPH in three years and, because she’s such an underachiever, went on to pursue a storied career thus far representing the voice of the patient at every company she’s worked for; including The National Brain Tumor Society, Takeda Oncology, Bluebird Bio, and now as the VP of Patient Affairs at X4 Pharma. She’s also traversed ALL SEVEN continents in a quest to find herself, make sense of the madness, and live her life on her terms. So, prepare yourself for an inspirational conversation amongst friends, and if my “conversation amongst friends” I mean “eavesdropping on our first phone call in 7 years,” well, then you’re in for a treat. Learn more about the Children’s Cause for Cancer Advocacy
December 1, 2020

[BONUS] “Jen Horonjeff is Noncompliant” COVID-19 Vaccine Edition

Today's episode of "Jen Horonjeff is Noncompliant" riffs off the news of Pfizer's COVID-19 vaccine safety and efficacy data. Jen has a convo with Matthew Zachary that starts off about vaccines and quickly dives off the deep end into a sea of public perception, personal preferences, and medical ethics. Tune in as we wade through how ableism, veganism, and animal memorial services relate to life-saving medicines. It's all proof positive that developing a vaccine is only half the battle and must be coupled with a robust communication strategy if we want widespread adoption of a COVID-19 vaccine.
November 30, 2020

Is Our Healthcare System Working Exactly as Planned?

Today’s show takes us in a different but related direction into the dumpster fire of health insurance pertaining to employer-based care. Joining me is David Contorno, Founder of E Powered Benefits, which itself sounds jargony. Still, I assure you, he’s one of the more controversial and outspoken whistleblowers advocating in the space, and you may be surprised at all of the aha and gestalt moments revealed on the show. Everyone knows that there are benefits when we take a job, but what exactly are those benefits? Do we really read all the fine print? Does the employer genuinely have our interests in mind vs. the overly enticing cost-saving measures that limit your choices? Are we blindly accepting the iTunes Terms Of Service without reading all the fine print? It’s easy to confuse, comport, and conflate healthcare for health insurance. In the end, it all comes down to who writes the check on your behalf. Unfortunately the perversion of incentive-based care too often skews the medical establishment toward making recommendations and decisions on our behalf that are better for them than for us. It’s nice to say the healthcare system is broken, but the real conspiracy is that there isn’t one because this broken system is actually working by design and exactly as it was planned. Buckle up and enjoy the show. Learn more about David on LinkedIn.
November 24, 2020

3-2-1 Contact: The Medidata Show with Glen de Vries

On the show today, I welcome Glen DeVries, Co-CEO at Medidata, the most used platform for clinical trials worldwide. Not too shabby, I say. Among many other things, we dig into his new book, "The Patient Equation: The Precision Medicine Revolution in the Age of COVID-19". Glen is unique in the annals of woke brainiacs who live in the hyper multi-syllable world of science, data, and related semantic geekery AND YET he is hyperaware that average Jane's and Joe's like you and I prefer to actually understand the words emanating from the mouths of "science people" that may or may not be critical in helping us make life-altering medical decisions. Yes, Glen is The De-Jaronator, says me. He's a controversial and authentic personality. As a bonus, he's also an 80's nostalgia junkie like me, so prepare for some random pop culture references that you may or may not need to IMDB. We also chat about Moore's Law and how it applies to the intersection of biology and technology, how we might need to reframe the concept of an impending robot apocalypse, and whether HAL from 2001: A Space Odyssey could be our future gatekeeper to a clinical trial. This episode moves pretty fast. If you don't stop and listen around once in a while, you could miss our reference to SneakerNet. More at
November 19, 2020

[BONUS] “Jen Horonjeff is Noncompliant” with Gabe Howard

On today's episode of "Jen Horonjeff is Noncompliant," Jen talks with Gabe Howard, patient advocate, author of "Mental Illness is an Asshole," and host of the PsychCentral podcast. As a "mental health advocate," Gabe first unpacks how ridiculous it is that all mental health gets lumped together. And herein lies the problem: There is often a one-size-fits-all approach to mental health, one that usually leaves many people behind, especially those who lack essential resources like food, shelter, and insurance, as well as tech and broadband. Please tune in to hear the barriers many patients face when trying to improve and maintain their mental health, along with some of the best analogies you've ever heard. More about Gabe Howard here.
November 18, 2020

Introducing the #BCSM Podcast

Today, instead of my usual shenanigans, I’d like to treat you to something very special that we have been working on here at OffScrip Media.One of the privileges we have here besides creating and producing epic shows on our network like Am I Dying, Brave New Weed, and NORDpod, is the ability to diversity and expand to producing original series — and we think you’re really going to like what you’re about to listen to. We are handing over the entirety of today’s show to episode 1 of The #BCSM Podcast, a 3-part narrative about how breast cancer patients dared to be the change they wished to see, saw an opportunity to fill a need and created the Breast Cancer Social Media Community, or BCSM. What began in 2011 as a conversation on Twitter between two intrepid young adult breast cancer survivors has evolved into a global network of patients, caregivers, clinicians, and researchers dedicated to empowering those affected by breast cancer. Once you listen to this episode, I urge you to subscribe to the series by searching for B-C-S-M in your favorite podcasting app. This is a labor of love for us. I promise you: you will not be disappointed. And now, without further ado, please enjoy episode one of BCSM.
November 17, 2020

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Out of Patients with Matthew Zachary

Today's healthcare conversations are too polite. We're here to fix all that. Hosted by Matthew Zachary, a 25-year brain cancer survivor, and the Founder of Stupid Cancer, Out of Patients with Matthew Zachary is a podcast that calls out all sorts of stupid BS in healthcare through raw conversations about advocacy, heroism, and the audacity of health.
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Matthew Zachary

Matthew Zachary

My name is Matthew Zachary. I am your advocate.

Why? Because when you enter the "Shit Happens" store, there's no one to greet you. I spent most of my 20s in that store. For those like me, who are lucky enough to have completed their shopping, I believe it to be incumbent upon us to become the greeters we wished we had.

In 2007, I founded Stupid Cancer and gave birth to the young adult cancer movement. The Stupid Cancer Show broke all the rules and gave a voice to millions.

And now it's time to go OffScrip. Join me on this new adventure as I continue to galvanize the patient voice, blow up the status quo, and make big dents in the universe.

After all, we are all very fortunate to not have ordinary lives.

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