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The Science Behind PMDD: Hormonal Shifts, Brain Chemistry, and More

Hopeful Hints: An Infertility Podcast

The Science Behind PMDD: Hormonal Shifts, Brain Chemistry, and More

The Science Behind PMDD: Hormonal Shifts, Brain Chemistry, and More
November 14, 2023

The Science Behind PMDD: Hormonal Shifts, Brain Chemistry, and More

Why do hormonal fluctuations affect some individuals more than others? How does progesterone’s metabolite allopregnanolone traverse the blood-brain barrier to influence mood? And what role do neurotransmitters like serotonin and GABA play in the manifestation of PMDD? We’ll be dissecting these questions and give you an in-depth understanding of PMDD’s multifaceted nature.

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