Impulse – Meeting Healthcare Pioneers

What will the future of surgery look like? According to Dr. George Papagiannakis, we must count on virtual simulation. After all, simulators are an integral part of professional training in highly demanding fields like aviation or F1. So why not medicine? The approach might seem futuristic, but George and his team at ORamaVR share a vision that makes a lot of sense. Integrating extended reality in surgery means increasing the volume of hours spent operating. It means preparing each surgery on a virtual patient with properties close to the real case. It means simulating complications and unforeseen situations safely. And it means reducing the risk of errors in the real world. Following his motto "never first time with the real patient", George immerses us in the universe of extended reality and reveals its potential for medicine and surgery. What is extended reality? What makes a good virtual medical simulation? And what is the impact of this technology today and in the future? Many questions that George addresses with passion and enthusiasm, in a conversation reminiscent of Ready Player One! Timeline: 02:49 - Addressing the millions of fatal medical errors worldwide 05:20 - Defining extended reality and underlying technologies 07:31 - Medical applications of extended reality 10:52 - The impact of extended reality on medical training and practice 16:25 - What makes a virtual medical environment feel real 23:32 - How to recreate the feel of touch and dexterity virtually 29:28 - Enabling all healthcare professionals to create virtual environments with AI What we also talked about with George: Prof. Shafi Ahmed Apple Vision Pro Magic Leap Microsoft HoloLens NHS The Anatomy Lesson of Dr. Nicolaes Tulp by Rembrandt IKEA Global illumination Dall-E ChatGPT NotebookLM Frost & Sullivan Meta We cited with George some of the past episodes of the series: #9 - Creating the Gran Turismo of surgery - Raimundo Sierra - Virtamed #12 - Unleashing the power of digital health - Daniel Kraft - Digital.Health #32 - Accelerating radiology with AI - Amine Korchi - Radiologist #36 - Turning healthcare preventive with full-body MRI scans - Andrew Lacy As mentioned by George during the episode, we recommend taking a look at some of the simulations available on the official YouTube channel of ORamaVR, it will bring to life many aspects that we discuss in the episode! You can follow ORamaVR’s activities on LinkedIn, Instagram, and get in touch with George via LinkedIn! If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!

To discover the whole episode type "#42 - Extending reality to transform surgery - George Papagiannakis - ORamaVR" on your preferred streaming platform.

Our gut contains a world of microorganisms that impact many aspects of our health, well beyond the gastrointestinal system. In fact, more than 30 trillion bacteria, archaea, fungi, and viruses live in the digestive tract of every human, a number that is higher than the number of human cells that make up our body! Each microbiome is unique to an individual, and its genetic heritage represents approximately 100 times that of the human genome. This field is fascinating and science is advancing rapidly, as evidenced by the 2,000 publications generated monthly on the subject. A better understanding of this remarkable ecosystem might bring critical answers to address numerous pathologies and health disorders. This is the mission of Leo Grady and his team at Jona, whose technology enables microbiome analysis based on an at-home test, combined with artificial intelligence to reveal what the current literature says about each person's microbiome. Unveiling the propensity for certain disease risks, along with individual nutritional preferences, Jona can model the body's reaction according to potential changes in the microbiome, and provide valuable insights on behaviors and nutrition that can ultimately improve one’s health. A dive into the heart of the microbiome and its secrets, which today's technology is about to unlock! Timeline: 02:32 - Leo’s journey from his PhD in computer vision to AI applications in medicine 06:47 - The idea behind Jona and understanding the microbiome better 10:33 - What we do know and ignore about the microbiome 13:05 - The Jona test kit and what it can interpret from one’s microbiome picture 20:17 - The volume and complexity of studies around the microbiome 22:11 - The impact of Jona and Leo’s son's story 25:38 - Who is Jona for 29:00 - Leo’s vision for the future of Jona and AI in healthcare What we also talked about with Leo: Neural networks Siemens HeartFlow Paige AI Memorial Sloan Kettering Crohn’s disease Thomas Clozel We cited with Leo some of the past episodes of the series: #32 - Accelerating radiology with AI - Amine Korchi - Radiologist #35 - Making surgery smarter and safer - Björn Von Siemens - Caresyntax #36 - Turning healthcare preventive with full-body MRI scans - Andrew Lacy - Prenuvo #40 - Cracking biology through AI - Jean-Philippe Vert - Owkin As mentioned by Leo during the episode, we recommend looking at the Jona Journal which sheds light on the latest findings on the microbiome fueled by their research platform, and understanding the current literature. Leo also recommends listening to The Mind-Gut Conversation Podcast by Emeran Meyer to find out more, and We Contain Multitudes by Sarah Henstra as a complementary read. You can follow Jona’s activities on LinkedIn, X, Instagram, and YouTube, and get in touch with Leo via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!

To discover the whole episode type "#41 - Making sense of the gut microbiome - Leo Grady - Jona" on your preferred streaming platform.

All experts agree: if there's one sector that AI will transform, it's healthcare. Whether it's understanding pathologies, developing personalized treatments, the doctor-patient relationship, diagnostic methods, or creating tools to facilitate the work of healthcare professionals, everything is affected by the ongoing transformation! This revolution raises many expectations and questions about the real impact these new technologies will have on tomorrow's medicine. One of the leading figures in this movement on the international scene is none other than the French-American company Owkin, which aims to be "the first end-to-end AI biotech company," whose R&D activities are overseen by Jean-Philippe Vert, himself a true pioneer in the field of machine learning and computational biology. The first “AI-first” biotech company of its kind, bringing a breath of fresh air to an industry known for being extremely costly and time-consuming. So how does AI accelerate the development of new therapies? What is its role in identifying new molecules and targets? How can it be used to create new diagnostic tools? Can we leverage patient data without compromising their safety and privacy? And what can we expect from future models and their impact on our understanding of biology? These are all fascinating questions that Jean-Philippe breaks down with pedagogy and realism, shedding light on one of the most exciting fields of medicine in this era! Timeline: 04:21 - Jean-Philippe’s background at the interface of mathematics, computer science, and life sciences 07:10 - Owkin’s mission to become the first end-to-end AI biotech firm 09:48 - Leveraging AI for drug discovery and new treatment modalities 14:35 - Selecting target indications and therapeutic areas 17:13 - Changing the way we run clinical trials through AI 22:03 - Unlocking patient data across hospitals while preserving safety and privacy 25:40 - Developing AI-based diagnostics and driving clinical adoption 34:50 - Towards the first AI foundation model to understand biology What we also talked about with Jean-Philippe Google DeepMind Large Language Models (LLMs) Digital twins External control arms Federated learning Digital pathology MSIntuit CRC Bioptimus Neural networks As mentioned by Jean-Philippe during the episode, we recommend taking a look at Owkin and Bioptimus websites as well as their respective Publications & News section to learn more about their technology and stay posted on their latest activities. If you are a data scientist or machine learning enthusiast, you can tackle one of the many biology-related challenges proposed by Kaggle on their platform. To learn more about Owkin’s portfolio and the diversity of biomarkers and health conditions they cover, take a look at their Pipeline section. You can follow Owkin’s activities on LinkedIn, X, and YouTube, and Bioptimus on LinkedIn and X. To get in touch with Jean-Philippe, contact him over LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!

To discover the whole episode type "#40 - Cracking biology through AI - Jean-Philippe Vert - Owkin" on your preferred streaming platform.

Among pioneering companies in connected health devices, few have been as forward-thinking as Withings, a flagship of French technology. Their first connected scales date back to 2009 (when smartphones were still emerging!) and remain the industry standard today. For that time, it was a subtle blend combining sleek design, intuitive user experience, and medical precision. A formula that Withings has successfully applied and developed in many other areas, from smartwatches to sleep sensors, thermometers, blood pressure monitors, or even a urinalysis device for your toilet! Their portfolio covers a wide range of medical parameters and helps hundreds of thousands of individuals manage their health daily. Matthieu Menanteau is one of the minds behind Withings' creations over the past 8 years. In this highly insightful episode, he shares Withings' philosophy and approach to creating the ultimate connected health experience, one that allows everyone to better understand themselves and take control of their health journey. We discuss: Withings' philosophy to innovate successfully in today's connected health sector Three development pillars that form the essence of Withings products The ongoing integration of consumer health with health systems and telemedicine The power of continuous medical data in the age of AI and big data A conversation that brings new perspectives on the future of connected health, and how technology can integrate into our daily lives to guide us toward healthier behaviors! Timeline: 03:45 - Withings’ origins and vision for connected health 07:18 - Providing the ultimate health companion 10:03 - Biomarkers and indications covered by Withings 13:11 - A home urinalysis laboratory 17:44 - Bringing the medical check-up at home 21:11 - A dual approach to driving innovation in connected health 26:20 - Towards an overwhelming mass of connected health devices? 31:47 - Withings’ three pillars of product development 38:05 - The role of AI in creating the ultimate connected health experience What we also talked about with Matthieu: Type 2 diabetes Lean mass Visceral fat Hydration pH Vitamin C Ketones Oxygen saturation Cuffless blood pressure measurement Apple CE mark FDA Edge computing Doctolib Alan CES We cited with Matthieu some of the past episodes of the series: #21 - Transforming hypertension care with a bracelet - Jay Shah - Aktiia #23 - Disrupting the smart wearables industry - Leo Grünstein - Spiden As mentioned by Matthieu during the episode, we recommend taking a look at the Research section of the Withings website, to learn more about current and future publications surrounding their products. To learn more about their portfolio and the diversity of biomarkers and health conditions they cover, take a look at their Products section. You can follow Withings’ activities on LinkedIn, X, Instagram, and YouTube, and get in touch with Matthieu via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!

To discover the whole episode type "#39 - Crafting the best connected health experience - Matthieu Menanteau - Withings" on your preferred streaming platform