Clinical Research and Drug Discovery Podcasts
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Latest Episodes
NEJM This Week — January 21, 2021
Featuring articles on inhibiting BCL11A to treat sickle cell disease and β-thalassemia, a polypill with or without aspirin in primary prevention, and neutralizing-antibody therapy in Covid-19; a review article on the effects of infection on natural immunity; a case report of a pregnant woman with ventricular tachycardia and shock; and Perspective articles on testing in a pandemic, on the Supreme Court and pandemic controls, and on incarceration and social death. Supplement to the New England Journal of Medicine, Vol. 384, No. 3.
January 20, 2021
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If you give people coverage, they use it
Listen to Health Affairs Editor-in-Chief Alan Weil interview Dr. Jeral Self, a researcher at Mathematica and an adjunct faculty member at the Tulane School of Public Health and Tropical Medicine, on how Medicaid expansion affected health care utilization for adults experiencing homelessness in Arkansas.
January 19, 2021
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What could Medicaid and COVID-19 vaccine distribution look like under a Biden administration?
Listen to editors Chris Fleming and Jessica Bylander discuss the COVID-19 vaccine rollout and what the Biden administration may do with Medicaid block grants and work requirements.
January 15, 2021
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NEJM This Week — January 14, 2021
Featuring articles on omecamtiv mecarbil in systolic heart failure, sotagliflozin in diabetes with heart failure, sotagliflozin for heart failure in diabetes and kidney disease, bupropion and naltrexone for methamphetamine use, and procuring oligodendrocytes after spinal cord injury; a review article on Ewing’s sarcoma; a case report of a woman with lethargy and altered mental status; and Perspective articles on the Purdue Pharma opioid settlement, on drug-coated devices for peripheral arterial disease, and on the doctor as street-level bureaucrat. Supplement to the New England Journal of Medicine, Vol. 384, No. 2.
January 13, 2021
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And the value of an additional star for physicians and hospitals is…
Listen to Health Affairs Editor-in-Chief Alan Weil interview Adam Schwartz, associate professor of orthopedic surgery at the Mayo Clinic College of Medicine and Science, on the fiscal value of an additional hospital or physician star rating when choosing a provider for total joint replacement.
January 12, 2021
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Health policy on the table in 2021 with democratic Congress
Listen to editors Leslie Erdelack and Rob Lott start 2021 by discussing the Georgia runoff election, the fall of Haven, the coverage provisions in the 2021 appropriations and COVID-19 stimulus package, and what is all means for health policy.
January 8, 2021
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NEJM This Week — January 7, 2021
Featuring articles on sitagliptin for prevention of acute GVHD, tocilizumab in Covid-19 pneumonia, rilonacept in recurrent pericarditis, vaginal mother-to-child transmission of cancer, and on whether the melanoma epidemic is real; a review article on osteoarthritis of the knee; a Clinical Problem-Solving on breathing for two; and Perspective articles on human molecular genetics and genomics, on Covid-19 and the undocumented Latinx community, and on the stress of Bayesian medicine. Supplement to the New England Journal of Medicine, Vol. 384, No. 1.
January 6, 2021
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Value-based care isn’t transforming healthcare spending
Listen to Health Affairs Editor-in-Chief Alan Weil interview Sherry Glied, dean of the Robert F. Wagner Graduate School of Public Service at New York University, on national healthcare spending in 2019, whether value-based care will be transformational, and why public health is a desirable field to work in now.
January 5, 2021
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Overlooked health policy stories of 2020 – Part 2
Listen to Leslie Erdelack, Vabren Watts, and Jessica Bylander discuss some of health policy's overlooked stories thanks to the COVID-19 pandemic. In a special extended episode of Health Affairs This Week, the group highlights drug pricing and regulations, the public charge rule, and the increase in health literacy due to the pandemic.
December 31, 2020
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NEJM This Week — December 31, 2020
Featuring articles on the safety and efficacy of an RNA-based SARS-CoV-2 vaccine, dexamethasone in chronic subdural hematoma, sleuthing out a severe adult inflammatory disorder, hemoglobin transfusion thresholds in infants, and vaccinating against SARS-CoV-2; a review article on the pathophysiology of inflammatory bowel diseases; a case report of a man with memory loss and odd behavior; and Perspective articles on reimagining how policymakers identify safety-net hospitals, on Medicaid and child health equity, on the FDA approval of remdesivir, and on whiteouts. Supplement to the New England Journal of Medicine, Vol. 383, No. 27.
December 30, 2020
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From Colorado to Washington: Editor-in-Chief Alan Weil discusses his past, healthcare’s future
We turn the tables in this episode and ask Health Affairs Editor-in-Chief Alan Weil about his educational background, what it means to be the editor for the leading health policy journal, how empirical research has changed since the COVID-19 pandemic, his views on social determinants of health, and his health policy predictions for 2021.
December 29, 2020
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Overlooked health policy stories of 2020 – Part 1
Listen to Leslie Erdelack, Chris Fleming, and Rob Lott discuss some of health policy's overlooked stories thanks to the COVID-19 pandemic. In a special extended episode of Health Affairs This Week, the group highlights the ACA turning 10, antitrust regulations, and environmental rollbacks.
December 24, 2020
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NEJM This Week — December 24, 2020
Featuring articles on ultrasound subthalamotomy for Parkinson’s disease, antenatal dexamethasone for early preterm birth, oral azacitidine maintenance therapy for AML, paclitaxel-coated devices in peripheral artery disease, and seizure frequency during pregnancy; a review article on estrogen receptor–positive breast cancer; a case report of a man with headache and Covid-19; and Perspective articles on the gift; on new order, new hope; on resilience in the face of Covid-19; and on holding up. Supplement to the New England Journal of Medicine, Vol. 383, No. 26.
December 23, 2020
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Healthcare take note: every greenhouse gas emission matters
Health Affairs Editor-in-Chief Alan Weil interviews Dr. Kristie Ebi, a professor in the Department of Global Health at the University of Washington, on the complex relationship between climate change and human health.
December 22, 2020
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Snow can’t stop the COVID-19 vaccine supply chain
Listen to Jessica Bylander and Vabren Watts enter the snow discourse and discuss the latest on COVID-19 vaccines.
December 18, 2020
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NEJM This Week — December 17, 2020
Featuring articles on SARS-CoV-2 transmission among Marine recruits, SARS-CoV-2 transmission on an aircraft carrier, an mRNA vaccine against Covid-19 in older adults, a phase 1 trial of an RNA-based Covid-19 vaccine, and the cardiomyocyte and the mighty mitochondrion; a review article on severe Covid-19; a case report of a boy with seizure and hypocalcemia; and Perspective articles on health coverage and care for transgender people, on rethinking sex designations on birth certificates, on being interviewed while Black, and on the caregiver. Supplement to the New England Journal of Medicine, Vol. 383, No. 25.
December 16, 2020
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Can climate change solutions be served with school lunches?
Health Affairs Editor-in-Chief Alan Weil interviews Mary Kathryn Poole, a PhD student in population health sciences at the Harvard T.H. Chan School of Public Health, on how school lunch programs could affect planetary health.
December 15, 2020
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Climate change and the future of health policy
Leslie Erdelack and Chris Fleming discuss why health policy is ready to enter the climate change discussion.
December 11, 2020
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NEJM This Week — December 10, 2020
Featuring articles on lipid lowering through activation of lipoprotein lipase, on a SARS-CoV-2 recombinant nanoparticle vaccine, on tocilizumab in Covid-19, and on survival with olaparib in prostate cancer; a review article on spontaneous coronary-artery dissection; a case report of a man with cancer and acute hypoxemia; and Perspective articles on the discovery of hepatitis C, on how Medicare Part D has failed to deliver savings to older adults, on a pandemic within a pandemic, and on Telephone. Supplement to the New England Journal of Medicine, Vol. 383, No. 24.
December 9, 2020
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When climate change impacts Indigenous identities, mental health suffers
Health Affairs Editor-in-Chief Alan Weil interviews Shasta Gaughen, director of the Pala Environmental Department for the Pala Band of Mission Indians, on how climate change is affecting the culture and health of Indigenous communities.
December 8, 2020
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Is a COVID-19 vaccine within reach?
Health Affairs' Jessica Bylander and Rob Lott chat about COVID-19, vaccine distribution, emergency use authorization for vaccines, toddlers' interpretations of masks, and mistrust over the healthcare industry.
December 4, 2020
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NEJM This Week — December 3, 2020
Featuring articles on pembrolizumab in microsatellite-unstable colorectal cancer, the effect of finerenone on chronic kidney disease outcomes, person-to-person spread of Andes virus, malaria chemoprophylaxis in sub-saharan Africa, and epigenetic regulation in prostate cancer; a review article on cytokine storm; a Clinical Problem-Solving on looking for the outsider; and Perspective articles on solving population-wide obesity, on the bottom of the health care rationing iceberg, on understanding questions and answers about Covid-19 vaccination, and on why we need black physicians in academic medicine. Supplement to the New England Journal of Medicine, Vol. 383, No. 23.
December 2, 2020
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‘What are we going to do about it?’: An essay on racism and health inequities
Listen to Brooke Cunningham, general internist and assistant professor at the University of Minnesota, reflect on how the health effects of racism become embodied for her and other Black Americans.
December 1, 2020
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NEJM This Week — November 26, 2020
We discuss the latest in medical research and ideas.
November 25, 2020
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