Featuring articles on tirofiban for stroke, a five-year follow-up after transcatheter repair of secondary mitral regurgitation, diagnostic imaging for pediatric forearm fractures, and AKT pathway inhibition in HR-positive breast cancer; a review article on adipose tissue and insulin sensitivity; a Clinical Problem-Solving describing a wrong turn; and Perspective articles on ensuring a reliable platelet supply, on supporting robust teamwork, and on an invitation to lunch. Supplement to the New England Journal of Medicine, Vol. 388, No. 22.

2023-01-27 Join us as we discuss ChatGPT and the place it may have in the decentralized clinical trials space. Our hosts, Craig Lipset, Amir Kalali, and Jane Myles were joined by Joe Dustin (Medable) and Ritesh Patel (FINN Partners) for this riveting conversation.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-01-20 On this episode of TGIF-DCT, our hosts Craig Lipset & Jane Myles were joined by Jon Meyer (Life Sciences Strategy Group) to discuss his research on patient preference. 2/3 of study participants want to see trial have more in-home features and only 9% want fewer. And in-home activities in trials were associated with greater patient satisfaction than those involving travel.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

We believe in the power of the patient voice to provide inspiration and hope to others in similar situations. That’s why we were thrilled to sit down with John Linnell, an individual who lives with COPD and who, since his diagnosis, has been advocating for COPD awareness, resources, and research.   John Linnell, COPD Patient John was diagnosed in 2005 and his journey led him to key roles in advocacy, in which he is active. John is a member of the Board of Directors for the US COPD Coalition and is an Advocacy Captain for the COPD Foundation. He serves on the Executive Board of Directors for EFFORTS (an international support group for the COPD community), a member of the Governing Board for the COPD PPRN (Patient Powered Research Network), and the Board of Directors of Right2Breathe, a nonprofit emphasizing early diagnosis and patient education. John also sat as a Consumer Reviewer for CDMRP (Congressional Directed Medical Research Programs) for the Department of Defense and now mentors new Consumer Reviewers.   John was a Co-investigator for a 3-year PCORI-funded study at Johns Hopkins: “Impact of a Peer Support Program Amongst COPD Patients and Their Caregivers”.   CMS/Medicare recently appointed John to a term as a patient representative on a Technical Expert Panel for the 2024 Impact Assessment of CMS Quality and Efficiency Measures.He also was asked to join the Patient Engagement Collaborative for the FDA. He also is a Patient Scholar for DIA (Drug Information Association) and spoke at their annual international conference this past year.   In addition, John is a frequent speaker and/or panel member at numerous national conferences dealing with both respiratory issues as well as advising digital health start-up enterprises as a Patient Advisor.

Join hosts Craig Lipset and Amir Kalali as they discuss Patient Choice & Optionality in DCTs. Joined by Michelle Shogren (Innovate in what you do!), Kelly McKee (Medidata), Alexander Pastuszak (Now Contraline, preiously Vault Health), and Angela Radcliffe (BMS).Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

Featuring articles on hydrocortisone in severe community-acquired pneumonia, a meningococcal vaccine in Mali and Gambia, platelet transfusion before CVC placement in patients with thrombocytopenia, and upadacitinib therapy for Crohn’s disease; a review article on using AI to interpret medical images; a case report of a boy with depression and hypotension; and Perspective articles on U.S. law and discrimination in health care, on enhancing regulations to reduce exposure to PFAS, and on public health’s role in a post-Dobbs world. Supplement to the New England Journal of Medicine, Vol. 388, No. 21.

The commitment of pharmacy to address clinical trials has been a recurring topic this week. Craig Lipset was joined by Kendal K. Whitlock, MPH, Head of Digital Optimization, RWE Clinical Trials from Walgreens to discuss the state of the industry, commitment to the field, and progress to-date.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

The first full day of the #WHA76 - speeches and networking. (Not) Taiwan and Russia on the UN floor. Behind the scenes, efforts brewing to ensure we don't forget COVID, as the world prepares for the "polycrises" that face us... Elisha are joined by Lois Chingandu, Frontline AIDS. This is a special live streamed series with the Global Health Council.

The Global Health Council is joining A Shot In The Arm Podcast to provide accessible, daily updates on all the news coming out of the 76th World Health Assembly. In this introductory episode, Ben Plumley and GHC President & CEO Elisha Dunn-Georgiou explore what to expect, from a pandemics treaty, Universal Health Coverage,  non-communicable diseases, a diagnostics declaration, to the fight to secure greater transparency & accountability in how decisions are made by this august body, in the age of polycrisis. https://globalhealth.org https://www.who.int/about/governance/world-health-assembly https://www.who.int https://unaids.org https://www.ashotinthearmpodcast.com #WorldHealthAssembly #WHA76 #WorldHealthOrganization #WHO #GlobalHealthCouncil #GHC #UNAIDS #pandemicspreparation #pandemicstreaty #UniveralHealthCare #UHC #UNAIDS #NonCommunicableDiseases #NCDs #mentalhealth #climatehealth #transparency

Featuring articles on transcatheter repair for tricuspid regurgitation, rifapentine in household contacts of persons with leprosy, peresolimab for rheumatoid arthritis, and emodepside for T. trichiura and hookworm infections; a review article on tricuspid regurgitation; a case report of a man with paresthesia of the arms and legs; and Perspective articles on advancing community living for people with disabilities, on essential steps for abolishing disability injustice, and on the thin pane. Supplement to the New England Journal of Medicine, Vol. 388, No. 20.

We had a delightful conversation with Dr. Kirk Hinkley and Matt Pavlichko, RT for at Vapotherm. We discuss their high velocity therapy and how it saved lives during the pandemic and continues to be an alternative method for patients who are mask-intolerant. Kirk Hinkley, MD, FACEP Dr. Kirk Hinkley is Vapotherm’s Director of Education and a board-certified Emergency Medicine Physician having completed his EM residency at Wright State University/Wright Patterson AFB in 2007. He is the Medical Director of Commonwealth Health EMS and City of Scranton Fire Dept, where he maintains clinical oversight of several EMS units, and practices as an Emergency Physician in the Scranton, PA area.  He went to medical school on a United States Air Force Scholarship and served in Operations Iraqi Freedom and Enduring Freedom as a critical care air transport team leader and flight surgeon. Dr. Hinkley is an experienced user of high velocity therapy for the adult and pediatric patient. Matthew S. Pavlichko, MS, RRT-NPS Matt is the Director of Professional Development and Education, Respiratory Therapy at Vapotherm. He has been in the respiratory therapy field for over 25 years, practicing in South Central Pennsylvania and North Carolina as a respiratory therapist, educator, manager, and director, managing all aspects of respiratory care.  We want to bring you the most relevant podcast, to do that we need your feedback. Please take our 5-to 7 minute survey, so that we can provide you an even better Podcast experience. Survey Link-https://lp.constantcontactpages.com/sv/qeVnHmK/PodcastSurvey     

Featuring articles on anti-CD20 antibodies and venetoclax in chronic lymphocytic leukemia, epicutaneous immunotherapy in toddlers with peanut allergy, cabozantinib in advanced renal-cell carcinoma, and racial inequality in the receipt of medications for opioid use disorder; a review article on HPV vaccination; a case report of a man with redness of the right eye; and Perspective articles on addressing serious illness care in Medicare Advantage, on corporate citizenship and institutional responses post-Dobbs, and on ethical conflicts for clinicians under Tennessee abortion law. Supplement to the New England Journal of Medicine, Vol. 388, No. 19.

2023-04-28 TGIF-DCT discussed understanding and addressing site adoption barriers for DCT. Host Craig Lipset, Amir Kalali, and Jane Myles were joined by Michelle Shogren and Sarah McKeown-Cannon to discuss further.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-04-14 What favorite consumer experience should be included in clinical trials? Joe Dustin joined hosts Craig Lipset, Amir Kalali, and Jane Myles for this discussion. Joe's initial LinkedIn post sparked a lot of great interest and response from the Community so we brought it to the stage this week.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-03-10 This week we discussed the Form 1572 and whether or not it is an obstacle to innovative approaches for improving research access for patients. Hosts Craig Lipset, Amir Kalali, and Jane Myles were joined by Shaalan Beg (Science 37) and John Campbell (Walgreens) to discuss.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-03-03 In honor of Rare Disease Day, we discussed Patient Advisory Boards and Decentralized Trials with hosts Craig Lipset and Jane Myles. Our hosts were joined by Alicia Staley (Medidata) and Jen Horonjeff (Savvy Cooperative).Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-02-24 Join us to discuss special considerations for GDPR with eConsent and decentralized trials. Hosts Craig Lipset and Jane Myles were joined by Karen Maduschke (IQVIA) to talk about her recent article, linked here.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-02-17 Join us to discuss whether a community physician can "prescribe" a clinical trial and what the role of decentralized trial tools are to make that happen. Craig Lipset and Jane Myles were joined by Brad Hightower (Hightower Clinical) and Scott Stout (MedVector) to discuss more.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-02-11 We discussed the Best Practices Handbook created by the Initiative Team at DTRA. This team developed a Rubric thst will aid stakeholders in evaluating DCT best practices from program planning to trial close and analysis. Hosts Craig Lipset, Amir Kalali, and Jane Myles were joined by Mike DeMarco (PwC) and Dan DeBonis (EMA Wellness, formerly Signant Health) to discuss the work their team did to drive this deliverable forward for the community. You can review the Rubric at https://dtraresources.org/rubrics/.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-02-03 Join us to discuss sensors and wearables in clinical trials and what the unmet needs are to execute successfully. We also discussed what it will take to drive meaningful adoption in R&D. Hosts Craig Lipset, Amir Kalali, and Jane Myles were joined by Megan Parisi and Dr. Luke Koschalka (Syneos Health) to discuss more.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-03-31 Join hosts Craig Lipset and Jane Myles as they open the floor for an #AMA Ask Me Anything DCT Edition. We welcomed attendees to come to the stage and share their questions and ideas with the audience.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-03-24 Join us as we discuss DTRAs Patient Journey Maps for Decentralized Trials and how to use them to improve design and access for your next trial. Hosts Craig Lipset and Jane Myles were joined by Co Leads of the DTRA Initiative Team, Richie Kahn (Canary Advisors, formerly Medable), and Alicia Staley (Medidata Solutions) and Project Manager Deena Bernstein (Datacubed Health) to discuss the great work done at the DTRA to create this dynamic resource. View the Oncology, Vaccines, and Rare Disease journey maps at https://dtraresources.org/Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

2023-03-17 Join us to learn how study teams can best navigate the grwing new options of virtual/meta-sites, mobile research sites, retail pharmacy sites, pop-up sites, and more? Hosts Craig Lipset and Jane Myles were joined by Sandeep Bhat (GSK) and Darcy Forman (Science 37) for this conversation.Follow the Decentralized Trials & Research Alliance (DTRA) on LinkedIn and Twitter. Learn more about Membership and our work at www.dtra.org.

Featuring articles on interrupting therapy to attempt pregnancy after breast cancer, trifluridine–tipiracil and bevacizumab in colorectal cancer, imaging- or angiography-guided PCI for complex lesions, and idiopathic CD4 lymphocytopenia; a review article on neonatal seizures; a Clinical Problem-Solving describing a diagnostic sequence; and Perspective articles on combating West Nile virus disease, on falling insulin prices, on next steps in policy reforms to address the overdose crisis, and on the breast biopsy and the Buddhist half-smile. Supplement to the New England Journal of Medicine, Vol. 388, No. 18.